ライフサイエンスコーパス: phenyl

1 ylation that restores the aromaticity of the phenyl.

2 techniques, which revealed cubes linked with phenyls.

3 enzylated 3-fluoro and 4-fluoro analogues of phenyl 1-thioglucosazide and galactosazide donors and ev

4 4-((4-(4-Bromophenyl)piperazin-1-yl)sulfonyl)phenyl)-1-propylxanthine (34, PSB-1901) was the most pot

5 tatically coated with a ~0.1 mum layer of 5% phenyl-1% vinyl-methylpolysiloxane (SE-54) stationary ph

6 PP(+) ) cell model and an in vivo 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) of PD were used

7 on the subacute dosing regimen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), producing bila

8 gnificantly down-regulated in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse m

9 ntials during normal sleep and in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkins

10 that several endogenously formed 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mimicking chemi

11 antia nigra (SN) and the serum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated hemiparkin

12 l-DOPA delivery to the putamen in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated rhesus monkeys

13 and muscle ARNT-like 1 (BMAL1) in 1-methyl-4-phenyl-1,2,4,5-tetrahydropyridine (MPTP)-treated mice re

14 The reaction of ABCDs with 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD) catalyzed by Yb

15 with the dienophiles maleic anhydride and 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD) to determine th

16 Ebselen (EBS), 2-phenyl-1,2-benzisoselenazol-3(2H)-one, is an organoselen

17 anisotropy of the probe N,N,N-Trimethyl-4-(6-phenyl-1,3,5-hexatrien-1-yl) was found to be the basic p

18 as PPT, 2,2',2"-(1,3,5-benzinetriyl)-tris(1-phenyl-1-H-benzimidazole) (TPBi), and poly(methyl methac

19 on) which primarily formed 3-(methylamino)-1-phenyl-1-propanol (TP 166) and 4-(trifluoromethyl)phenol

20 These data suggest the formation of 1-phenyl-1-propyne (C(6)H(5)CCCH(3)) via the barrierless a

21 In particular, 4-chlorobenzyl-4-hydroxy-2-phenyl-1-thia-2,7-diazaspiro[4,4]nonane 1,1-dioxide (com

22 of zinc(II) (5,15-bis[3,4,5-tri(2-butyloctyl)phenyl]-10,20-bis(ethynyl)porphyrinate) with N, N'-bis(

23 -(3-{2-[(4-oxo-4H-chromen-7-yl)oxy]acetamido}phenyl) (12j).

24 xy-4-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-phenyl-1H-imidazol-5-yl)phenol (H23), as a first-in-clas

25 Bronsted diacid ligand, H(2) L (H(2) L=2-[5-phenyl-1H-pyrazole-3-yl] 6-benzimidazole pyridine), show

26 form of [2,6-bis(5-(2,4,6-trimethylphenyl)-3-phenyl-1H-pyrrol-2-yl)pyridine].

27 A new strategy for the construction of 3-phenyl-1H-pyrrolo-imidazo[1,2-a]pyridine backbone is des

28 ycosylation, to show also high efficiency of phenyl 2-azido-2-deoxy-selenogalactosides as glycosyl do

29 ansporting large-bandgap polymer (poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine (PTAA)) is employed

30 l-1,2,4-oxadiazoles 3a-c into the relevant 2-phenyl-2 H-1,2,3-triazoles (4a-c) have been measured in

31 hesized and characterized, where Hphbpy = 6'-phenyl-2,2'-bipyridyl, and N-N = bpy (2,2'-bipyridine),

32 ) in acetonitrile (MeCN) with 1,3-dimethyl-2-phenyl-2,3-dihydro-1H-benzo[d]imidazole (BIH) as sacrifi

33 e the sacrificial behavior of 1,3-dimethyl-2-phenyl-2,3-dihydro-1H-benzo[d]imidazole as an electron d

34 5 x 10(-3) m), and a photoinitiator (lithium phenyl-2,4,6-trimethylbenzoylphosphinate at 1 x 10(-3) m

35 a recently discovered cascade assembly of N-phenyl-2,5-dimethylpyrrole from one molecule of aniline

36 The alternative mechanism of N-phenyl-2,5-dimethylpyrrole self-assembly, which involves

37 e synthesized new nNOS inhibitors based on 7-phenyl-2-aminoquinoline and assayed them against rat and

38 s confirmed by mutagenesis studies, making 7-phenyl-2-aminoquinolines the first aminoquinolines to in

39 anism for the binding of the ditopic guest N-phenyl-2-naphthylammonium cation (Ph-AH(+)-Np) to cucurb

40 de-, carbamate-, and carbonate-substituted 2-phenyl-2-oxazolines with mixed lithium-magnesium amides

41 eramide analog d-threo-1-(3,4,-ethylenedioxy)phenyl-2-palmitoylamino-3-pyrrolidino-1-propanol (EtDO-P

42 3-Methyl-1-phenyl-2-phospholene 1-oxide was used as a precatalyst a

43 ring FDM, including 4-vinylcyclohexene and 2-phenyl-2-propanol.

44 tion of N-[4-(1-cyclobutyl-piperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide dihydrochloride (17v

45 ation of 5-[4-fluoro-2-(1-methyl-4-piperidyl)phenyl]-2-oxo-N-pentyl-oxazole-3-carboxamide 32b as a po

46 ion in the conversion of the single-bonded 3-phenyl-2H-1,4-benzothiazine dimer 2 to the Delta(2,2('))

47 rearrangement of benzonitrile imine forms 3-phenyl-3 H-diazirine, which is a precursor of phenyldiaz

48 ted monosaccharides were then labeled with 1-phenyl-3-methyl-5-pyrazolone (PMP) followed by separatio

49 The carbon analogue of EBS, namely, 2-phenyl-3H-isoindol-1-one, was included as a reference co

50 rted a 3-(2-methoxyphenyl)-9-(3-((4-methyl-5-phenyl-4 H-1,2,4-triazol-3-yl)thio)propyl)-3,9-diazaspir

51 muscle cells treated with the NO scavenger 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide or

52 itionally, the synthetic usefulness of the 3-phenyl-4-(phenylselanyl)isoquinoline-2-oxide was demonst

53 ) 0.0192 muM) and N-[3,5-bis(trifluoromethyl)phenyl]-4-chloro-2-hydroxybenzamide (14, IC(50) 0.0231 m

54 he photochemical CO release from 3-hydroxy-2-phenyl-4H-chromen-4-one, a pai-extended 3-hydroxyflavone

55 rocoumarin derivative (2-(cyclohexylamino)-3-phenyl-4H-furo[3,2-c]chromen-4-one, FH), exhibits strong

56 One of the prepared compounds, 3-phenyl-5-((phenylselanyl)methyl)-isoxazoline, demonstrat

57 Electrostatic effects on a range of 2-phenyl-5-methyltetrazoles, 2-methyl-5-phenyl-tetrazoles,

58 potent compounds, N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide (1, IC(50) 0.0192 mu

59 The 9-phenyl-9-fluorenyl (PhF) group has been used as an N(alp

60 ence (TADF) compound, 3-(4-(9H-carbazol-9-yl)phenyl)acenaphtho[1,2-b]pyrazine-8,9-dicarbonitrile (CzP

61 lopropyl methyl, cyclopentyl methyl, benzyl, phenyl, acetate, and acetamide groups, which smoothly pr

62 one, ethyl 2-[2,3,4-trimethoxy-6-(1-octanoyl)phenyl]acetate (TMPA), and three high-throughput screeni

63 Cu(20) H(11) {S(2) P(O(i) Pr)(2) }(9) ] with phenyl acetylene in the presence of Pd(PPh(3) )(2) Cl(2)

64 The boron persulfide formally inserted phenyl acetylene into the B-S bond in the presence of Li

65 eport glutathione (GSH) reaction rates for N-phenyl acrylamides with varied substitutions at the alph

66 y, we provide compelling evidence on a novel phenyl-addition/dehydrocyclization (PAC) pathway leading

67 Introducing a phenyl aglycon moiety next to the galactoside ligands on

68 pyridine scaffold is a good bioisostere for phenyl, allowing the further optimization of this molecu

69 nge and one, 2-((4-fluoro-3-(trifluoromethyl)phenyl)amino)-3-(methylthio)naphthalene-1,3-dione (1), d

70 ( R)-2-((2-ethoxy-4-(1-methylpiperidin-4-yl)phenyl)amino)-7-ethyl-5-methyl-8-((4-methylthiophen-2-yl

71 y the TAAR1 agonist RO5166017 ((S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine) in c

72 lightly more sterically demanding than their phenyl analogue but considerably less flexible.

73 Unlike the methyl-substituted analogue, the phenyl analogue exhibits a dual emission (cyan and red)

74 -thiols and their 3-nitro-5-(trifluoromethyl)phenyl analogues.

75 the SubPz electronic properties produced by phenyl and biphenyl moieties attached to the vinylene en

76 ations containing the p-(pentafluorosulfanyl)phenyl and m-(pentafluorosulfanyl)phenyl groups have bee

77 mension ((1)D), and five (C18, amide, cyano, phenyl and PFP) in the second dimension ((2)D) were comb

78 -tuning of the dihedral angle between the C4 phenyl and the dihydropyrimidine core of the heteroaryld

79 Indol-1-yl, pyrrol-1-yl, phenyl, and naphtylallenes might be used.

80 e rate of deprotection for the corresponding phenyl aryl sulfonates increases with decreasing electro

81 on of a number of asymmetrically substituted phenyl azides in acetonitrile was studied.

82 e protocol is also equally effective for the phenyl aziridine with excellent regio- and stereoselecti

83 of a variety of N-sulfonyl heterocycles and phenyl benzenesulfonates to the corresponding desulfonyl

84 n of N,N'-dimethylurea derivatives to a meso-phenyl-beta,beta'-dioxoporphyrin, followed by oxidative

85 tion of pharmaceutical compounds (Metformin, Phenyl biguanide, and Phenformin) of varied hydrophilici

86 w the successful incorporation of a range of phenyl bioisosteres during the open-source optimization

87 ence of sodium tetrakis[(3,5-trifluoromethyl)phenyl]borate (NaBARF).

88 ve complexation of glucose and fructose with phenyl boronic acid (PBAc) followed by ethyl-acetate ext

89 Key synthetic transformations include phenyl boronic acid-mediated 6pai-electrocyclization rea

90 nduced reaction of pentyl bromide (PeBr) and phenyl bromide (PhBr) on Cu(110) at 4.6 K, observed by s

91 ene, as well as a chemoselective coupling of phenyl bromides in the presence of phenyl chlorides.

92 w bench-stable trifluoromethylation reagent, phenyl bromodifluoroacetate, converts readily available

93 l-4-yl)butyl]-4-{(1E,3E)-4-[4-(dimethylamino)phenyl]buta-1,3-dienyl}-2,6-dimethylpyridinium hydrotrif

94 yl-(11)C](+/-)-7-methoxy-3-(4-(4-(methylthio)phenyl)butyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ol

95 hyperoxia, the free radical scavenger alpha-phenyl-butyl-tert-nitrone (alphaPBN), and the N-methyl-D

96 ting ER stress with the chemical chaperone 4-phenyl butyric acid (4-PBA).

97 l4a1 mutant mice with the chemical chaperone phenyl butyric acid (PBA), which reduced adult ICH.

98 D administered with 0.5 g/kg bodyweight of 4-phenyl butyric acid (PBA, a small chaperone known to eas

99 emonstrate tandem devices using the PDTIDTBT:Phenyl-C(61)-butyric acid methyl ester (PC(60)BM) blend

100 We demonstrate OPVs based on the PDTIDTBT:Phenyl-C(61/71)-butyric acid methyl ester (PCBM) blend w

101 ted from the 19 structural isomers of bis[60]phenyl-C61-butyric acid methyl ester, using them to eluc

102 upling of phenyl bromides in the presence of phenyl chlorides.

103 22) was found to be equipotent to its parent phenyl compound and showed significantly improved metabo

104 Plasmodium falciparum compared to the parent phenyl compound; however, these changes resulted in a re

105 4-position with variations of cyclohexyl- or phenyl-containing fragments to reduce rotatable bonds an

106 s, Ir[TpXPC)]L(2), where TpXPC = tris(para-X-phenyl)corrole (X = CF(3), H, Me, and OCH(3)) and L = py

107 perhalogenation of five ReO meso-tris(para-X-phenyl)corroles, Re[TpXPC](O) (X = CF(3), H, F, CH(3), a

108 The 6-cyclohexyl-6-phenyl derivative 3b, with a cis configuration between t

109 that efficient iSEF is only observed for the phenyl-derivative in ~2.4 ps while absent in the other t

110 lectronic structure calculations reveal that phenyl-DPP bridge localizes alpha- and beta-spin densiti

111 Sixfold phenyl embraces are well-established aromatic interactio

112 efficient electronic delocalization over the phenyl ends as the oligophenylene branch is enlarged.

113 LOQs using FLD for flavanols, stilbenes and phenyl ethanol analogues were improved between 65 and 10

114 e, diethyl succinate, hydroxylinalool, and 2-phenyl ethanol was responsible for describing the BRS Ru

115 hasic hydrogenolysis of (13)C-labeled benzyl phenyl ether (BPE, a model compound for the major beta-O

116 Exocyclic 2,4,6-tris(trifluoromethyl)phenyl ((F) Mes) groups serve not only to further withdr

117 ed to a more potent agent, 2-(fluorosulfonyl)phenyl fluorosulfate with IC(50) 0.24 muM and greater th

118 2) (pin=pinacolato, trip=2,4,6-tri(isopropyl)phenyl) for 15 min is sufficient for efficient generatio

119 A new additive, methyl(phenyl)formamide (MPF), is introduced for the glycosylat

120 As determined by PBE+D3 calculation, the phenyl fragment reveals strong pai-pai interaction for s

121 formation of covalently-linked hexadecyl and phenyl functionalized magnesium silicates (MSil-C16 and

122 11)C]methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide], a positron-emitting, high-a

123 cyclo[3.2.2]nonan-4-yl(5-(3-(trifluoromethyl)phenyl)furan-2-yl)methanone (NS6740).

124 T (N-[N-(3,5-Difluorophenacetyl)-l-alanyl]-S-phenyl glycine t-butylester) abrogates GH-induced epithe

125 olenine moiety, with either an n-propyl or a phenyl group alongside a methyl group, were synthesized

126 Hydrazones bearing EDGs at the stator phenyl group are an exception and show up to 6 orders of

127 fluorescent protein (GFP) chromophore with a phenyl group at C(2) of the imidazolone has been synthes

128 bination with a four-carbon chain carrying a phenyl group at position-3 and a linear propyl group at

129 The indolenine precursors with a phenyl group attached at the chiral center were asymmetr

130 m via intramolecular metal-metal cooperative phenyl group C(sp(2))-H oxidative addition to the dinick

131 The pendant phenyl group can be used to modify the intrinsic optoele

132 in of the dual emission was dependent on the phenyl group in the Z-isomer, which stabilizes the Franc

133 n step in which the substrate's carboxylated phenyl group makes a nucleophilic attack to form the pyr

134 s is highly affected by the existence of the phenyl group on the alkyne terminus.

135 ors the enantiomorph containing a deuterated phenyl group over the protio or (13)C version, and the p

136 in the active site, with the pai-face of the phenyl group positioned over the heme iron atom.

137 differ only in the isotopic composition of a phenyl group positioned remote from the chiral center.

138 n of the PP or SP with a 3,4-(methylenedioxy)phenyl group was also examined.

139 ethylene linker, (ii) replacing the terminal phenyl group with less lipophilic heterocycles, or (iii)

140 as resistant to nintedanib analogs lacking a phenyl group.

141 ha-carbon preceding functionalization of the phenyl group.

142 e Ru atom is coordinated by the P atom and a phenyl group.

143 ptical properties, where the introduction of phenyl groups caused a progressive red-shift and reducti

144 rphyrin), where the 2-position of one of the phenyl groups contains -NH(2), -N(CH(3))(2), and -N(CH(3

145 hdrawing and -donating substituents on the 3-phenyl groups has been prepared and characterized.

146 rosulfanyl)phenyl and m-(pentafluorosulfanyl)phenyl groups have been characterized by low-temperature

147 er family, consist of alternating alkene and phenyl groups in conjugation.

148 teractions with the piperazine, anilino, and phenyl groups of nintedanib, providing a structural basi

149 YNPHOS) containing 3,5-bis(trimethylgermanyl)phenyl groups on phosphorus and applied this ligand to t

150 nation interactions restrict the rotation of phenyl groups on tetraphenylethene units, these metallac

151 ties to ortho- or para-positions of the meso-phenyl groups.

152 =CPh(2) [1b: Ar(F) = 2,6-bis(trifluoromethyl)phenyl] have been prepared, isolated, and characterized.

153 mode reversed-phase chromatography, on a CSH Phenyl-Hexyl column, to accomplish mixed-mode anion-exch

154 coupler carbonyl cyanide p-(trifluoromethoxy)phenyl-hydrazone (FCCP); the mitochondrial calcium unipo

155 In this study, the benzene/phenyl hydride equilibrium is explored for the {WTp(NO)(

156 n pathways connecting the eta(2)-benzene and phenyl hydride isomers, due to the relatively flat energ

157 tional theory calculations of the benzene-to-phenyl hydride landscape suggest a single linear sequenc

158 clooctadiene, IMes = 1,3-bis(2,4,6-trimethyl-phenyl)imidazole-2-ylidene) in the presence of an excess

159 study, three stationary phases (C18, PFP and phenyl) in the first dimension ((1)D), and five (C18, am

160 ion based on the readily available 2-azido-2-phenyl-indan-1,3-dione is described.

161 ors (e.g., ZCZ011) featured a 3-nitroalkyl-2-phenyl-indole structure.

162 droxy-3-((E)-((4-hydroxyphenyl)imino)methyl) phenyl)isobenzofuran-1(3H)-one (HMBP) was designed as a

163 accessible l-proline derived aminocatalyst, phenyl l-prolinamide, for asymmetric tandem oxa-Michael-

164 In situ-formed dibromo(phenyl)-lambda3-iodane (PhIBr(2)) is proposed as the rea

165 electrophilic cyanating reagent, 2-methyl-2-phenyl malononitrile (MPMN).

166 reversibly join two [3-(1-acylpiperidin-4-yl)phenyl]methanamine core ligands, we have successfully pr

167 table phosphane probe (2-(diphenylphosphanyl)phenyl)methanol as a C-terminus activator has been demon

168 ET ligand (11)C-PBR28 (N-((2-(methoxy-(11)C)-phenyl)methyl)-N-(6-phenoxy-3-pyridinyl)acetamide) binds

169 Methods: (11)C-PBR28 (N-((2-(methoxy-(11)C)-phenyl)methyl)-N-(6-phenoxy-3-pyridinyl)acetamide) PET s

170 ons [4-(tert-butyl)-propofol and 4-(hydroxyl(phenyl)methyl)-propofol] bind with ~10-fold higher affin

171 c-2,3-dimethylacrylamides and proceeded with phenyl migration in the case of an N-Boc-2-phenylacrylam

172 ane (BCP) have been used as highly effective phenyl mimics.

173 port the synthesis and characterization of P-phenyl modified phosphorus- and nitrogen-containing phos

174 =5 mM), whereas the inclusion of the smaller phenyl moiety in CB[7] (CB[7]@Ph-AH(+)-Np) is transient.

175 he Na(+) ion stabilizes the inclusion of the phenyl moiety in CB[7] by capping the portal of CB[7].

176 This stabilization of the phenyl moiety inclusion in CB[7] by Na(+) leads to the f

177 C-Alkoxycarbonyl- C-phenyl- N-aryl ketenimines bearing 1,3-dithiolan-2-yl or

178 ylbutyl)oxazole-3-carboxamide 8a and 2-oxo-5-phenyl-N-(4-phenylbutyl)oxazole-3-carboxamide 12a, which

179 al optimization of our initial hits, 2-oxo-4-phenyl-N-(4-phenylbutyl)oxazole-3-carboxamide 8a and 2-o

180 acid (BA) using N-3,5-bis-(trifluoromethyl)-phenyl-N-4-vinylphenyl urea (1) as the functional host m

181 New derivatives of alpha-phenyl-N-tert-butyl nitrone (PBN) bearing a hydroxyl, an

182 chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide).

183 emote C-H activation, a synthetically useful phenyl nitrile functional group could also direct remote

184 ere is that the simple swap of 1-methyl to 1-phenyl on 1-(benzoyloxymethyl)CPEs elicited strikingly d

185 x) moieties connected to an aromatic bridge (phenyl or bithiophene) by ethylenic junctions.

186 the N-tert-butyl moiety and para-substituted phenyl or naphthlyl moieties were synthesized.

187 lene) wires with one tetrapodal anchor and a phenyl or pyridyl head group.

188 notably for a compounds with either a rigid (phenyl) or flexible (butyl) unit at the core.

189 tion of substrate selectivity toward indole, phenyl, or hydroxyphenyl amino acids in plant AAADs.

190 Here, we identified N-phenyl oxamic acid as a highly potent and selective mono

191 ng functional groups such as p-hydroxymethyl phenyl, p-hydroxyphenyl, p-cyanophenyl, p-nitrophenyl, a

192 ormation product of N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), a globally ubiquitous

193 atrices, namely 1,5-diaminonaphthalene and N-phenyl-p-phenylenediamine were applied that yield ISD ma

194 tuted benzhydryl benzoate Ar(2)CH-OBz to the phenyl(perfluorophenyl)iodonium ion was found to follow

195 Herein, we propose a strategy to strengthen phenyl-perfluorophenyl polar-pai interactions by encapsu

196 Phenyl-perfluorophenyl polar-pai interactions have been

197 potentials are tuned by the substitution of phenyl (Ph), 3,4,5-trifluorophenyl (PhF(3)), or 2,3,4,5,

198 (3)Au-C=CR, where R = nitrophenyl (PhNO(2)), phenyl (Ph), thiophene (Th), bithiophene (biTh), and dim

199 R; R = Alkane (Ak), ethylene glycol (EG) and phenyl (Ph).

200 = 5.0, non-CEST-detectable enzyme substrate phenyl phosphate was converted to CEST-detectable phenol

201 e free energy surfaces of the reduction of 1-phenyl phospholane 1-oxide with four different silanes.

202 iated imprinting of the mono- or dianions of phenyl phosphonic acid (PPA), phenyl sulfonic acid (PSA)

203 o-tetra(alpha,alpha,alpha,alpha-o-pivalamido-phenyl)porphyrin, or TpivPP, 1-MeIm = 1-methylimidazole)

204 s-2-bis[4-(2-hydroxy-3-methacryl-oxypropoxy)-phenyl]-propane (Bis-GMA) and 2-hydroxyethyl-methacrylat

205 that flavanoid pathway, lignin biosynthesis, phenyl propanoid pathway, pigment biosynthesis, and othe

206 The required enantiopure phenyl propanoid unit was prepared from readily availabl

207 scaffold linked via a benzodioxane ring to a phenyl propanoid unit, resulting in the compound being a

208 ives of benzoic acid, phenylacetic acid, and phenyl propionic acid in the cecal contents following ce

209 e 6-endo-dig cyclization of [2-(butylselanyl)phenyl]propynols promoted by the cooperative action betw

210 and dCF(3)ppy is 2-(3,5-bis(trifluoromethyl-phenyl)pyridine), were found to be remarkably strong pho

211 Recently, we identified phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimida

212 y exploring these reaction mechanisms of the phenyl radical with biphenyl/naphthalene theoretically a

213 uinazolinone core and the 4'-position of the phenyl residue.

214 with one-dimensional hexagonal channels and phenyl-rich pore surfaces for the recognition and sensin

215 ducing an additional phenyl ring to the N-10 phenyl ring (subtype 11) or to the N-3 site of the deaza

216 s bioisosteric replacements of a fluorinated phenyl ring and properties such as lipophilicity, solubi

217 unctional group reveals the influence of the phenyl ring and the pyridine ring, respectively.

218 g materials with various substituents on the phenyl ring and varied functional moieties, producing st

219 the fastest 1,5-H shift is achieved when one phenyl ring carries an electron-donating group and the o

220 en atom addition to the ipso position of the phenyl ring concerted with C-O scission.

221 unds with either no substitutions on the TPE phenyl ring containing the antiestrogenic side chain of

222 elationships of PSNCBAM-1 (2) at the central phenyl ring directly connected to the urea moiety.

223 eads to a close approach between PS2 and the phenyl ring edge of Phe-232 that is surrounded by pairs

224 tems, and aldehydes/ketones, having an alpha-phenyl ring have been employed successfully to afford th

225 o optimize these properties, we replaced the phenyl ring in the compound with a pyridine ring and syn

226 ctivity of the alkyne terminus not bearing a phenyl ring is because the cyclization is thermodynamica

227 sponding Re complexes (Re-1-3), in which the phenyl ring of 2-phenylbenzothiazole or 2-phenylbenzimid

228 Adding an ortho substituent on one phenyl ring of a prochiral diazo enhances enantioselecti

229 rption through a strong interaction with the phenyl ring of acetophenone activates the Pt(111) and Pt

230 4-addition of two central silicon atoms to a phenyl ring of an amidinate ligand coordinated to the Si

231 onditions, hydroxyl radicals can oxidize the phenyl ring of phenylalanine, producing the abnormal tyr

232 talyst to activate the ortho-C-H bond of the phenyl ring of the benzylamine.

233 peb), are induced by rotation of the central phenyl ring of the linker, from a coplanar arrangement t

234 ndium(III) and that meta-substituents on the phenyl ring of the substrate significantly influenced th

235 idely adopted in medicinal chemistry as para-phenyl ring replacements(2).

236 tiestrogens with a free para-hydroxyl on the phenyl ring that contains an antiestrogenic side chain i

237 of the complexes and the substituents on the phenyl ring that was explained within the context of cha

238 By introducing an additional phenyl ring to the N-10 phenyl ring (subtype 11) or to t

239 This modularity is achieved by appending a phenyl ring with different para-substituents from one ur

240 the ring-closed form is delocalized into the phenyl ring, and/or (ii) the lowest energy conformation

241 breaking the aromaticity of the neighboring phenyl ring, leading to rapid cleavage.

242 2-yl substituents at ortho position of the C-phenyl ring, respectively, transform into isoquinoline-1

243 In contrast to the phenyl ring, the pyridine ring has a very different effe

244 ed binding pocket to accommodate spiperone's phenyl ring, which probably contributes to the selectivi

245 y and sterically diverse substituents on the phenyl ring.

246 idues appended by different linkers on the 6-phenyl ring.

247 tivity relationship (SAR) studies on the two phenyl rings and amide nitrogen of the sulfonamide group

248 including destructive QI in meta-substituted phenyl rings and constructive QI in para-substituted phe

249 ophysics is governed by the twist of lateral phenyl rings and intramolecular and intermolecular CT tr

250 ings and constructive QI in para-substituted phenyl rings containing terminal oxazole groups with the

251 Lemniscates with four to eight phenyl rings in each loop having the N-N, C=C, or B-N bo

252 on of the boron atoms from the planes of the phenyl rings they are attached to.

253 The para-OH on the phenyl rings was beneficial for binding affinity while a

254 Surprisingly, meta-substituted phenyl rings with nonequivalent constitutions (i.e., O(4

255 i-HIV/EV71 activity is the presence of extra phenyl rings, bearing one or two carboxylates, at the C2

256 of halogen substitution in position 4 of the phenyl rings.

257 cs of a vibrational probe (the CN stretch of phenyl selenocyanate) in poly(methyl methacrylate) show

258 The effect of ethyne, ethene, and phenyl spacer units between the radical center and the i

259 ample of an isolated oxaphosphetane having a phenyl substituent at C3 of the ring.

260 o-(Trifluoromethyl)phenyl substituent contributes to stereoselectivity of 1

261 ed by incorporation of a radical-stabilizing phenyl substituent on the cyclopropyl group.

262 substituted with the p-(pentafluorosulfanyl)phenyl substituent, deviations from linearity when the H

263 interactions are absent in the complex with phenyl substituents on the borate backbone.

264 tral acene is encapsulated by the peripheral phenyl substituents, and as a result, the molecule is re

265 group adopting a sharp kink, and its N-CF(3)-phenyl substituted piperazine group reaching out to the

266 d for the production of both 1-methyl- and 1-phenyl-substituted 2,3-dihydroxybutanones at yields betw

267 ituted 3,4-dihydroxypentan-2-ones or 1,4 bis-phenyl-substituted butanones, respectively.

268 revealed a slightly twisted geometry for the phenyl-substituted cisoid squaraine derivative, whereas

269 d by aldol condensation with the pentamethyl phenyl-substituted ketone to form an enone containing th

270 Reduction of the phenyl-substituted phospholone resulted in the formation

271 docking studies suggested that the 4-methoxy-phenyl-substituted tetrahydroquinazolinamine compound 4c

272 -3-(N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid) allosterically activates

273 In experimental models of diabetes, phenyl sulfate administration induces albuminuria and po

274 Together, our results suggest that phenyl sulfate contributes to albuminuria and could be u

275 etary tyrosine before it is metabolized into phenyl sulfate in the liver, reduces albuminuria in diab

276 In a diabetic patient cohort, phenyl sulfate levels significantly correlate with basal

277 using untargeted metabolomics that levels of phenyl sulfate, a gut microbiota-derived metabolite, inc

278 in we report the optimization of a series of phenyl sulfonamides that exhibit a novel mode of binding

279 Instead, 3,5-bis(trifluoromethyl)phenyl sulfones were employed, thereby simultaneously re

280 or dianions of phenyl phosphonic acid (PPA), phenyl sulfonic acid (PSA), and benzoic acid (BA) using

281 ormed upon delithiation leads to several new phenyl sulfoselenide compounds which are confirmed by HP

282 l-imino form, in which the enol is part of a phenyl system and a strong O-H...N intramolecular hydrog

283 e of 2-phenyl-5-methyltetrazoles, 2-methyl-5-phenyl-tetrazoles, and 2,5-diphenyl-tetrazoles follow si

284 tBu)POCOP = 2,6-bis(di-tert-butylphosphinito)phenyl) that catalyzes CO(2) hydrogenation to formate wi

285 tzsch cyclization reaction forming 2-amino-4-phenyl thiazole from phenacyl bromide and thiourea.

286 bution in a series of pentacene dimers using phenyl-, thienyl- and selenyl- flanked diketopyrrolopyrr

287 bitors were identified among the synthesized phenyl(thio)phosphon(amid)ates 3-22.

288 activation-based glycosylation approach with phenyl thioglycosides.

289 V(-1) s(-1) ) for poly(3-(2-(4-hexylbenzoyl)phenyl)thiophene) was found to be significantly higher t

290 Poly(3-(2-(4-hexylbenzoyl)phenyl)thiophene) was found to have lower frontier orbit

291 Increasing the side chain size from phenyl to pyrenyl results in a rate acceleration of more

292 The 3-(4-(methoxycarbonyl)phenyl)triazapentalene is a highly fluorescent small mol

293 ilic Bi(V) species, which rapidly eliminates phenyl triflate.

294 in one high-yielding glycosylation with an N-phenyl trifluoroacetimidate donor.

295 facially stacked molecular pairs for varying phenyl units and reveal that orbital delocalization is r

296 n = 5-12, where n is the number of repeating phenyl units).

297 razin-1-yl)pyrimidin-4-ylamino]-thiazol-5-yl}phenyl)urea (10a) as a potent inhibitor against unactiva

298 4-(N,N-Diphenylamino)phenyl was chosen as the donor group and thien-2-yl dicy

299 chains (2-benzoylphenyl or 2-(4-hexylbenzoyl)phenyl), which influence the optical and electronic prop

300 ersus sigma(C(+)) or sigma(+) of classical 4-phenyl-X substituted carbocations also provides a means