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1 lting selenomelanin is a structural mimic of pheomelanin.
2 , neuromelanin, pyomelanin, allomelanin, and pheomelanin.
3 hair growth produces the red/yellow pigment pheomelanin.
4 the two major melanin classes, eumelanin and pheomelanin.
5 g protein (ASP) results in the production of pheomelanin.
6 and red hair contains 67% eumelanin and 33% pheomelanin.
7 e a ratio of two fluorophores, eumelanin and pheomelanin.
8 withc in melanin synthesis from eumelanin to pheomelanin.
12 ondestructively differentiates eumelanin and pheomelanin and can be used to quantify melanin distribu
13 the case of pigments containing a mixture of pheomelanin and eumelanin, of which NM is an example, ph
14 and blond hair contain 95% eumelanin and 5% pheomelanin; and red hair contains 67% eumelanin and 33%
15 results demonstrate that both eumelanin and pheomelanin are redox-active, they can rapidly (sec-min)
16 Hair shaft melanin components (eu- or/and pheomelanin) are a long-lived record of precise interact
18 model would predict a structural motif with pheomelanin at the core and eumelanin at the surface, wh
19 ontaining eumelanin are undistinguishable to pheomelanin-bearing organelles of extant vertebrates.
20 r X-ray protector than the sulfur-containing pheomelanin because the X-ray absorption coefficient is
21 contains approximately 99% eumelanin and 1% pheomelanin, brown and blond hair contain 95% eumelanin
22 lanocytes switch from producing eumelanin to pheomelanin concomitant with the down-regulation of mela
25 extended that work for imaging eumelanin and pheomelanin distributions on a subcellular scale, allowi
26 nd longer spectral emission (580-625 nm) and pheomelanin-enriched lighter pigmented HCM regions mappe
27 resent differing pigmentation types, such as pheomelanin, eumelanin, and non-pigmented areas within t
28 in and eumelanin, of which NM is an example, pheomelanin formation occurs first with eumelanin format
30 studies to date, some research suggests that pheomelanin has a better absorption coefficient for X-ra
32 is is the first time, to our knowledge, that pheomelanin has been visualized and spatially localized
37 elanin in black mice was three times that of pheomelanin in yellow mice, pheomelanin had 3-fold great
38 e of pigment synthesized, i.e., eumelanin vs pheomelanin, in mice carrying the black-and-tan mutation
39 duced photoprotection due to less eumelanin, pheomelanin-induced phototoxicity, and lower protection
40 ar color traits in Bengal cats, charcoal and pheomelanin intensity, are explained by selection of leo
41 cytes between the production of eumelanin or pheomelanin involve the opposing action of two intercell
44 strategy in vitro to in vivo with synthetic pheomelanin, isolated melanocytes, and the Mc1r(e/e), re
45 ce suggesting the red/blond pigment known as pheomelanin may elevate melanoma risk through both UV ra
46 nin is classified into five types-eumelanin, pheomelanin, neuromelanin, allomelanin, and pyomelanin-b
47 ude that UV-irradiated melanin, particularly pheomelanin, photosensitizes adjacent cells to caspase-3
49 that Slc7a11 is a major genetic regulator of pheomelanin pigment in hair and melanocytes, with minima
51 skin polymorphisms, produces the red/yellow pheomelanin pigment, whereas increasing MC1R activity st
53 that modulate the production of eumelanin or pheomelanin pigments involve the opposing effects of two
56 cle between oxidized and reduced states, and pheomelanin possesses a more oxidative redox potential.
58 complex mechanisms involved in the switch to pheomelanin production, and that these modulated genes m
60 sed as the ratio of the loge of eumelanin to pheomelanin ratio, with a dosage effect evident: MC1R ho
62 organosulfur-Zn complexes are indicators of pheomelanin (red pigment) in extant and fossil soft tiss
65 ay to melanoma carcinogenesis and implicated pheomelanin's pro-oxidant properties that act through th
68 wn melanogenic genes during the eumelanin to pheomelanin switch in murine hair follicle melanocytes a
69 strate that up-regulation of ITF2 during the pheomelanin switch is functionally significant and revea
70 od that actively measures both eumelanin and pheomelanin synthesis by fate tracing [U-(13)C] L-tyrosi
71 to produce cysteinyldopas, the precursors of pheomelanin synthesis made in melanosomes via cysteine o
74 we introduce this novel selenium analogue of pheomelanin through chemical and biosynthetic routes usi
76 s upon hydriodic acid hydrolysis showed that pheomelanin was also not produced by the fungus in vivo.
77 f a significant fraction of the red pigment, pheomelanin, which is characterized by a higher oxidatio
78 o compare the redox properties of human hair pheomelanin with model synthetic pigments and natural eu
79 ility to identify, characterize, and monitor pheomelanin within skin is vital for improving our under
80 atively profile the heterogeneous eumelanins/pheomelanins within in situ HCMs, and visualize melanoso