ライフサイエンスコーパス: phosphocholine

1 ol (e.g., glutathione, acetate, betaine, and phosphocholine).

2 and POPC (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine).

3 thickest bilayer (1,2-dierucoyl-sn-glycero-3-phosphocholine).

4 lower concentrations of choline, betaine and phosphocholine.

5 lar vesicles of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine.

6 ion between ATP and choline to yield ADP and phosphocholine.

7 nalyses reveal steric discrimination against phosphocholine.

8 olipid 1-palmitoyl-2-arachidonoyl-sn-glycero-phosphocholine.

9 embly of stable 1,2-diphytanoyl-sn-glycero-3-phosphocholine 1,2-diphytanoyl-sn-glycero-3-phosphocholi

10 hospholipid [1,2-dihexadecanoyl-sn-glycero-3-phosphocholine, 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'

11 1-palmitoyl-2-(9-oxo-nonanoyl)- sn-glycero-3-phosphocholine, 1-palmitoyl-2-azelaoyl- sn-glycero-3-pho

12 d of POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosph

13 into DMPC/DHPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine/1,2-dihexanoyl-sn-glycero-3-phosphoc holi

14 D-reconstituted 1,2-dimyristoyl-sn-glycero-3-phosphocholine/1,2-dimyristoyl-sn-glycero-3-phospho- (1'

15 asymmetric 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/1,2-dimyristoyl-sn-glycero-3-phosphocholi

16 nsisting of 1:1 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycero-3-phosphochol ine

17 cles composed of 1,2-distearoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycero-3-phosphocholine/

18 n GUVs composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine/1,2-palmitoyl-sn-glycero-3-phosphocholin

19 coli in mixed 1,2-diheptanoyl-sn-glycerol-3-phosphocholine/1-myristoyl-2-hydroxy-sn-glycero-3-p hosp

20 y hydrated 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/1-palmitoyl-2-oleoyl-sn-glycero- 3-phosph

21 ronment in 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/1-palmitoyl-2-oleoyl-sn-glycero-3-phospho

22 s, 14 amino acids, 9 lysophosphocholines, 72 phosphocholines, 10 sphingomyelins and sum of hexoses) a

23 the tear lipocalin-bearing fractions showed phosphocholines (104 ng/mL).

24 spholipid 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-PC), previously proposed to re

25 p methylation of phosphoethanolamine to form phosphocholine, a critical step in the synthesis of phos

26 rs prepared using 1,2-dilauroyl-sn-glycero-3-phosphocholine, a lipid with 12 carbon acyl chains, yiel

27 ed of zwitterionic 1,2-dioleoyl-sn-glycero-3-phosphocholine, a model for cell membranes, was reduced

28 structure of human alk-SMase in complex with phosphocholine, a reaction product.

29 excitations in 1,2-dipalmitoyl-sn-glycero-3-phosphocholine above and below the main transition tempe

30 s successively to their substrate to produce phosphocholine, an important precursor for phospholipid

31 anogels composed of dimyristoyl-sn-glycero-2-phosphocholine and 1,2-dihexanoyl-sn-glycero-3-phosphoch

32 mimics of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine and 1,2-dipalmitoyl-sn-glycero-3-phosphoc

33 oxy-3-methoxy) cinnamoyl-2-acyl-sn-glycero-3-phosphocholine and 1-(4-hydroxy-3,5-dimethoxy) cinnamoyl

34 symmetric 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine and asymmetric 1-palmitoyl-2-oleoyl-sn-gl

35 se) converts the lipid sphingomyelin (SM) to phosphocholine and ceramide and has optimum activity at

36 nts than into standard liposomes composed of phosphocholine and cholesterol using passive incubation.

37 ASD pup livers, with lower concentrations of phosphocholine and glycerophosphocholine in liver and hi

38 cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine and incorporating Na3[1-(2'-B10H9)-2-NH3B

39 The dynamics of phosphocholine and maltoside micelles, detergents freque

40 g and the exploration of ways to better tune phosphocholine and PC synthesis to environmental conditi

41 table isotope labeling, we demonstrated that phosphocholine and phosphatidylcholine biosynthesis was

42 together, our results indicate that enhanced phosphocholine and phosphatidylcholine synthesis support

43 We demonstrated previously that phosphocholine and phosphocholine-modified macromolecule

44 ratios of DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) and POPC (1-palmitoyl-2-oleoyl-sn-glycer

45 (5,8-dioxo-8-hydroxy-6-octenoyl)-l-glycero-3-phosphocholine, and others] in the aged lungs.

46 -Ficoll, production of natural antibodies to phosphocholine, and survival after intranasal pneumococc

47 [1-palmitoyl-2-(5-oxo-valeroyl)-sn-glycero-3-phosphocholine], and 1-palmitoyl-2-glutaroyl-sn-glycero-

48 functionality of polyclonal human IgG to the phosphocholine antigen was determined and showed that Ig

49 , and two zinc ions and one reaction product phosphocholine are identified in a histidine-rich active

50 Specifically, phosphocholines are frequently used detergents in NMR st

51 n) in water with 1,2-dihexanoyl-sn-glycero-3-phosphocholine as detergent.

52 r analog CLR1404, 18-(p-iodophenyl)octadecyl phosphocholine, as a scaffold for tumor-targeted radioth

53 ating samples of 1,2-distearoyl-sn-glycero-3-phosphocholine at 60 degrees C for 24-72 h yielded an in

54 in (alm) pore in a 1,2-dioleoyl-sn-glycero-3-phosphocholine bilayer at 313 K indicates that approxima

55 y hydrated 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine bilayer environment.

56 compound through a 1,2-dioleoyl-sn-glycero-3-phosphocholine bilayer is determined by molecular dynami

57 d show that in the 1,2-dioleoyl-sn-glycero-3-phosphocholine bilayer, charged residues of the protein

58 versely, in the 1,2-dimyristoyl-sn-glycero-3-phosphocholine bilayer, the overall hydrophobic-hydrophi

59 HLIP and a 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine bilayer.

60 ions results on the interaction of NaCl with phosphocholine bilayers have to be reconsidered and revi

61 f GA dimers from 1,2-distearoyl-sn-glycero-3-phosphocholine bilayers were significantly different for

62 supported DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) bilayers, deposited via the Langmuir-Blo

63 al divergence leading to the alteration of a phosphocholine binding pocket found in the staphylococca

64 es only the lipid class via formation of the phosphocholine cation.

65 o-3-phosphocholine/1,2-dioleoyl-sn-glycero-3-phosphocholine/cholesterol = 0.39/0.39/0.22 and a suppor

66 d lipid bilayer of 1,2-dioleoyl-sn-glycero-3-phosphocholine/cholesterol = 0.8/0.2, we observed the ex

67 Here, we show that phosphocholine (ChoP), a reaction product of the phospha

68 ange flux, the alkaline Pi-pool, and glycero-phosphocholine concentrations between the groups.

69 CTP:phosphocholine cytidylyltransferase (CCT) interconverts

70 Previous studies have shown that CTP:phosphocholine cytidylyltransferase (CCT) is an importan

71 CTP:phosphocholine cytidylyltransferase (CCT) is the key reg

72 CTP:phosphocholine cytidylyltransferase (CCT), the rate-limi

73 id, phosphatidylcholine, is catalyzed by CTP:phosphocholine cytidylyltransferase (CCT), which is regu

74 dylcholine biosynthesis is catalysed by CTP: phosphocholine cytidylyltransferase (PfCCT), which has a

75 Macrophage-specific knockout of phosphocholine cytidylyltransferase A (CCTalpha), the ra

76 conserved prokaryotic choline kinase and CTP:phosphocholine cytidylyltransferase activities with a 1,

77 he CDP-choline pathway for PC synthesis, CTP:phosphocholine cytidylyltransferase alpha (CCTalpha) is

78 The reversible association of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha) wit

79 mTORC1 promoted TAG secretion by regulating phosphocholine cytidylyltransferase alpha (CCTalpha), th

80 a key phospholipid biosynthetic enzyme (CTP:phosphocholine cytidylyltransferase alpha) and altered m

81 N-methyltransferase and hepatic-specific CTP:phosphocholine cytidylyltransferase alpha.

82 CTP:phosphocholine cytidylyltransferase-alpha (CCTalpha) and

83 way for PC biosynthesis was catalyzed by CTP:phosphocholine cytidylyltransferase.

84 pah1 pah2 is suppressed by disruption of CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE1 (CCT1), which encod

85 C) but not in thin 1,2-dioleoyl-sn-glycero-3-phosphocholine (DC(18:1)PC) lipid bilayer.

86 nction in a thick 1,2-dierucoyl-sn-glycero-3-phosphocholine (DC(22:1)PC) but not in thin 1,2-dioleoyl

87 line (DC22:1PC) or 1,2-dioleoyl-sn-glycero-3-phosphocholine (DC18:1PC) lipid vesicles using a fluores

88 nge of gA between 1,2-dierucoyl-sn-glycero-3-phosphocholine (DC22:1PC) or 1,2-dioleoyl-sn-glycero-3-p

89 e were identified in the presence of dodecyl phosphocholine detergent micelles.

90 th rhodopsin in 1,2-diheptanoyl-sn-glycero-3-phosphocholine (DHPC) micelles is investigated by soluti

91 oline (DMPC) and 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DHPC) self-assemble to form thermo-respo

92 In 1,2-dilauroyl-sn-glycero-3-phosphocholine (diC(12:0)PC) liposomes, the post-adsorpt

93 multibilayers of 1,2-dilauroyl-sn-glycero-3-phosphocholine (dilauroylphosphatidylcholine, DLPC) are

94 icles formed from 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC), we measured the frequency of blin

95 n the phospholipids dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and 1,2-dihexanoyl-sn-glycero-3-ph

96 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and its mixtures with different am

97 uid crystalline 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and POPC/POPS 3:1 liposomes retain

98 he phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and the saponin glycyrrhizin in th

99 tterionic lipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) are investigated as constructs for

100 in and MelP5 in 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) are repeated in POPC.

101 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes were the model system ch

102 ing kinetics in 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes, suggesting that lateral

103 phospholipids (1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phos

104 gle bilayers of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC)/1,2-dipalmitoyl-sn-glycero-3-phosp

105 man (liposomes of 1,2-dimyristoyl-sn-glycero-phosphocholine, DMPC) and the bacterial (liposomes of 1,

106 In stark contrast to choline, phosphocholine does not evoke ion current responses in X

107 the phosphocholine unit, a highly effective phosphocholine donor was synthesized.

108 composed of either 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) (fluid at room temperature) or 1,2

109 n efficiently bind 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) in nonpolar solvents.

110 TB) to a GM1-doped 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) lipid bilayer were investigated by

111 of an FDA-approved 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) lipid monomer.

112 scale, fluid-phase 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) liposomes contacting a titanium di

113 y of miR-630 using 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) nanoliposomes resulted in increase

114 cles membranes made of dioleoyl-sn-glycero-3-phosphocholine (DOPC) or 1-palmitoyl-2-oleoyl-sn-glycero

115 by spreading giant 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) vesicles on porous anodic aluminum

116 phocholine (DPPC), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), and 1-palmitoyl-2-oleoylphosphati

117 sed of zwitterionic 1,2-dioleoyl-sn-glyero-3-phosphocholine (DOPC), as well as DOPC vesicles, were us

118 ut not the control 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), binds directly to S6K and causes

119 ure SM/cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), focusing on the importance of the

120 pids investigated, 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)-based proteoliposomes were found t

121 ed lipids, such as 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC).

122 es in a bilayer of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC).

123 choline (POPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC).

124 holine (DPhPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)/1,2-dihexadecanoyl-sn-glycero-3-ph

125 lamellar vesicles [1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)/1,2-dipalmitoyl-sn-glycero-3-phosp

126 -phosphocholine 1,2-diphytanoyl-sn-glycero-3-phosphocholine (DPhPC) and 1,2-dioleoyl-sn-glycero-3-pho

127 temperature) or 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) (gel at room temperature) with a r

128 ary mixtures of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and asialo-(GA1), disialo-(GD1b) a

129 l properties of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayers using atomic force micros

130 cholesterol and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in the liquid-ordered (l(o)) and l

131 rtitioning into 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) lipid vesicles as a function of so

132 ffer, gel-phase 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) liposomes verified that the LSPR m

133 oline (DOPC)/1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) membranes.

134 having either a 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) or mixed-DPPC/cardiolipin membrane

135 ocholine (DMPC)/1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) phospholipid mixtures using quartz

136 bilayer lipids, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-dioleoyl-sn-glycero-3-phospho

137 ase behavior of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1-palmitoyl-2-oleoyl-sn-glycero-3

138 choline (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and 1-palmitoyl-2-oleoyl-sn-glyce

139 rs derived from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC).

140 ocholine (DOPC)/1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)], we report a dramatic influence o

141 o phospholipids, 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and 1,2-dipalmitoyl-sn-glycero-3-p

142 mes composed of 1, 2-distearoyl-sn-glycero-3-phosphocholine (DSPC), cholesterol and dimethyldioctadec

143 ted phospholipid 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), mixed with varying amounts of the

144 he structure we show that NetB does not bind phosphocholine efficiently but instead interacts directl

145 oline, 1-palmitoyl-2-azelaoyl-sn-glydecero-3-phosphocholine, efficiently opposes the miscibility tran

146 SM) hydrolyzes sphingomyelin to ceramide and phosphocholine, essential components of myelin in neuron

147 osphocholine and 1,2-dihexanoyl-sn-glycero-3-phosphocholine exhibit thermally reversible viscosity wi

148 3,5-dimethoxy) cinnamoyl-2-acyl-sn-glycero-3-phosphocholine exhibited excellent antioxidant activity

149 -methoxy) cinnamoyl-2-palmitoyl-sn-glycero-3-phosphocholine exhibited good antibacterial activity aga

150 droxy-3-methoxy) benzoyl-2-acyl-sn-glycero-3-phosphocholine exhibited good antifungal activity agains

151 imethoxy) cinnamoyl-2-palmitoyl-sn-glycero-3-phosphocholine exhibited good antioxidant activity with

152 fPMT methylates phosphoethanolamine (pEA) to phosphocholine for use in membrane biogenesis.

153 Its production involves the transfer of phosphocholine from phosphatidylcholine onto ceramide, a

154 LA2 and ENPP6 may act in concert to generate phosphocholine from the matrix vesicle membrane during s

155 n of S-adenosylmethionine, betaine, choline, phosphocholine, glyceophosphocholine, cystathionine, cys

156 ntified were choline, glycerophosphocholine, phosphocholine, glycine betaine, N-methylproline, prolin

157 partate (NAA) and glycerophosphocholine plus phosphocholine (GPC + PC), metabolites that are markers

158 Glycero-3-phosphocholine (GPC), the product of the complete deacyl

159 ng compounds (ie, glycerophosphocholine plus phosphocholine (GPC+PC)) in bipolar disorder using in vi

160 tosyl residues in glycosphingolipids and the phosphocholine group in phospholipids.

161 lipids consisting of the neutral loss of the phosphocholine head group was verified.

162 ored the effects of reducing the size of the phosphocholine headgroup (removing one, two, or three me

163 se results indicate that PC acyl editing and phosphocholine headgroup exchange between PC and diacylg

164 he enzyme that catalyzes the transfer of the phosphocholine headgroup from PC to DAG.

165 ith an HC surfactant carrying a zwitterionic phosphocholine headgroup gives rise to two coexisting mi

166 , accommodation of ceramide under the larger phosphocholine headgroup of SM could contribute to their

167 sodium ions with the phosphate moiety of the phosphocholine headgroups had a condensing effect on our

168 A small-molecule inhibitor of pCRP (1,6-bis(phosphocholine)-hexane), which blocks the pCRP-microvesi

169 tic target, we stabilized pCRP using 1,6-bis(phosphocholine)-hexane, which prevented dissociation in

170 Preincubation of these oocytes with phosphocholine, however, attenuated choline-induced ion

171 sphocholine and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine in the liquid-ordered (lo) and liquid-dis

172 ation with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, in bilayers with equal acyl chain order.

173 1-palmitoyl-2-(5'-oxovaleroyl)-sn-glycero-3-phosphocholine, in the lungs.

174 cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine, incorporating K[nido-7-CH3(CH2)15-7,8-C2

175 A structure in complex with phosphocholine indicates that the protein recognizes thi

176 mpounds exhibit a dose-dependent decrease of phosphocholine, inhibition of cell growth, and induction

177 In this study, we demonstrate that phosphocholine inhibits ion-channel function of ATP rece

178 ol% alpha-tocopherol in 1-palmitoyl-2-oleoyl-phosphocholine inhibits leakage of phenol red dye from l

179 The optimal binding frequency of CRP-phosphocholine interaction was determined to be 100 Hz.

180 es, the low binding affinity between CRP and phosphocholine is exploited in a "low-sensitive" sandwic

181 reatment of mice with the PHOSPHO1 substrate phosphocholine is sufficient to induce cold tolerance, t

182 ically distinct 1,2-dimyristoyl-sn-glycero-3-phosphocholine large unilamellar vesicle populations exh

183 ant lipid-related alterations were increased phosphocholine levels (increased 70% in endometrial canc

184 atment with the Akt inhibitor MK2206 reduced phosphocholine levels in MDA-MB-468 cells.

185 In a 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine lipid bilayer and a plasma membrane envir

186 w, using supported 1,2-dioleoyl-sn-glycero-3-phosphocholine lipid bilayers in different saline soluti

187 in was dispersed in diphytanoyl-sn-glycero-3-phosphocholine lipid bilayers, and the spectra and an ex

188 er carbonyl stretching vibration in hydrated phosphocholine lipid bilayers, we are able to measure a

189 erted into 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine lipid nanodiscs and the kinetics of activ

190 In this study, inverse phosphocholine lipids (CP) are used, directly exposing t

191 el membranes of 1,2-dimyristoyl-sn-glycero-3-phosphocholine lipids at pH > pHagg, we found that membr

192 onstituted into 1,2-dimyristoyl-sn-glycero-3-phosphocholine liposomes by (31)P MAS NMR.

193 ry with the aid of 1,2-dioleoyl-sn-glycero-3-phosphocholine liposomes.

194 rionic diC12:0PC (1,2-dilauroyl-sn-glycero-3-phosphocholine) liposomes and negatively charged 80:20 d

195 tic redox DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) liposomes by single collisions at 10 mum

196 ic) than in 1-lauroyl-2-hydroxy-sn-glycero-3-phosphocholine (LLPC, zwitterionic) micelles.

197 (POVPC), 1-palmitoyl-2-glutaroyl- sn-glycero-phosphocholine, lysophosphocholine, 1-palmitoyl-2-(9-oxo

198 induced ion current changes, suggesting that phosphocholine may act as a silent agonist.

199 -supported 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine membranes doped with different phosphoino

200 c membranes but mostly beta-sheet in neutral phosphocholine membranes.

201 tion structure of huntingtin 1-17 in dodecyl phosphocholine micelles and the topology of its helical

202 Rp were conducted in the presence of dodecyl phosphocholine micelles to solvate the membrane anchor o

203 maltoside micelles are more restricted than phosphocholine micelles.

204 that acetylcholine, choline, phosphocholine, phosphocholine-modified LPS from Haemophilus influenzae,

205 onstrated previously that phosphocholine and phosphocholine-modified macromolecules efficiently inhib

206 Of note, we identify receptors for phosphocholine-modified macromolecules that are synthesi

207 odified LPS from Haemophilus influenzae, and phosphocholine-modified protein efficiently inhibit ATP-

208 demonstrated in a step-wise manner that the phosphocholine-modified screen-printed carbon electrodes

209 ogical pH, is for substances bearing exposed phosphocholine moieties.

210 aviour of DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) multilamellar vesicles.

211 at citrate increased by HS, whereas choline, phosphocholine, N-acetylcarbohydrates, lactate, and B-hy

212 ry effects on companion pathway genes in the phosphocholine network.

213 holine, 1-palmitoyl-2-azelaoyl- sn-glycero-3-phosphocholine, O-1-O-palmitoyl-2-O-(5,8-dioxo-8-hydroxy

214 ormed with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine or cholesterol, phosphatidylserine, and p

215 inds to zwitterionic detergents that contain phosphocholine or phosphatidylcholine head groups and ph

216 ized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine [Ox-PAPC]) and proinflammatory cytokines

217 ized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (OxPAPC) and its derivatives were identif

218 ized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine [OxPAPC]) promote endothelial cell (EC) b

219 lyltransferases (PntCs) that prefer AEP over phosphocholine (P-Cho) - a similar substrate used by the

220 s of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (PAPC) oxidation that contain cyclopenthe

221 C isomers, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (PC(16:0/18:1)) and 1-oleoyl-2-palmitoyl-

222 18:1)) and 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine (PC(18:1/16:0)), were subjected to this i

223 phore featuring spatially separated urea and phosphocholine (PC) groups forms a macrocyclic "head-to-

224 Zwitterionic phosphocholine (PC) lipids are highly biocompatible, rep

225 nd 1,2-dioleoyl-sn-glycerophospholipids with phosphocholine (PC) or phosphoethanolamine (PE) substitu

226 s from Lip to yield diacylglycerol (DAG) and phosphocholine (PC) products, leading to the decompositi

227 phosphatase that catalyzes the hydrolysis of phosphocholine (PC) to choline.

228 rolysis of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (PC), a zwitterionic lipid.

229 Measures of phosphocholine (PC), glycerophosphocholine, and choline

230 sicle were made with varying compositions of phosphocholine (PC), phosphoethanolamine (PE), cholester

231 naling pathway and resulted in a decrease in phosphocholine (PC), total choline (tCho) and lactate le

232 Phosphocholine (PC)-containing OxPL (OxPC) present on pl

233 d as 1-hexadecyl-2-octadecenoyl-sn-glycero-3-phosphocholine [PC(16:0e/18:1)] using tandem mass spectr

234 This study shows that complexed CRP (phosphocholine [PC]:CRP) (formed by binding of CRP to PC

235 nds to cells and molecules that have exposed phosphocholine (PCh) groups.

236 The involvement of the phosphocholine (PCh)-binding property of CRP in its anti

237 Phosphocholine (pCho) is a precursor for phosphatidylcho

238 teryl esters (C18:2, C18:1, C16:0, C18:3), 8 phosphocholines (PCs) (C36:4 PC-A, C34:3 PC plasmalogen,

239 oyl-2-(5,6-epoxyisoprostane E2)-sn-glycero-3-phosphocholine, PEIPC, a proinflammatory molecule that a

240 d lipid, 1-palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine (PGPC), and each of the three bilayer lip

241 PC) and 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine (PGPC), are two major oxidation products

242 Phosphocholine phosphatase-1 (PHOSPHO1) is a phosphocholine phosphatase that catalyzes the hydrolysis

243 Phosphocholine phosphatase-1 (PHOSPHO1) is a phosphochol

244 rticle, we show that acetylcholine, choline, phosphocholine, phosphocholine-modified LPS from Haemoph

245 ng to produce Pi PHOSPHO1 is a dual-specific phosphocholine/phosphoethanolamine phosphatase enriched

246 y the transfer of the phosphoethanolamine or phosphocholine polar head group, respectively, to the di

247 1-palmitoyl-2-(9'-oxononanoyl)-sn-glycero-3-phosphocholine (PONPC), is of major interest as they pla

248 spholipids 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1,2-dioleoyl-sn-glycero-3-phos

249 omposed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1-palmitoyl-2-oleoyl-sn-glycer

250 icelles and a 1-palmitoyl-2-oleoyl-glycero-3-phosphocholine (POPC) bilayer showed that LPPG micelles

251 (HAs) with 1-palmitoyl-2-oleoyl-Sn-glycero-3-phosphocholine (POPC) large unilamellar vesicle (LUV) mo

252 nd neutral 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) liposomes.

253 ly bind to 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membranes, whereas Cl(-) ions stay

254 ructure of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membranes.

255 lations in 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) of hexamers of these peptides star

256 ospholipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) the two-state model was found to b

257 DPPC), and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)), and the average GM1 and choleste

258 ne (DPPC), 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), and cholesterol lipid membranes.

259 (DOPC) or 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), by irradiating methylene blue pre

260 the ApoA1-1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)-based particles are disk shaped wi

261 osition of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)-containing PDs at neutral pH diffe

262 1-palmitoyl-2-(5'-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC) and 1-palmitoyl-2-(9'-oxononanoyl

263 , 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC) and 1-palmitoyl-2-glutaroyl-sn-gl

264 f 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC) or 1-palmitoyl-2-glutaroyl-sn-gly

265 s [1-palmitoyl-2-(5-oxovaleroyl)- sn-glycero-phosphocholine (POVPC), 1-palmitoyl-2-glutaroyl- sn-glyc

266 ermine that SMase and its enzymatic product, phosphocholine, prevent Th2-mediated increases in alpha

267 on structures of PfPMT with pEA (substrate), phosphocholine (product), sinefungin (inhibitor), and bo

268 and inhibition of PHOSPHO1 or enhancement of phosphocholine represent innovative approaches to manage

269 CD36 in reducing inflammation induced by the phosphocholine residues of pneumococcal lipoteichoic aci

270 eta-(1 -> 3)-GalNAc; and phosphoglycerol and phosphocholine residues which have not been previously o

271 A modifications with D-alanyl, glycosyl, and phosphocholine residues will be discussed along with the

272 te that S. pneumoniae binds to cells via its phosphocholine residues, and suggest a role for CD36 in

273 ith S-adenosylhomocysteine and either pEA or phosphocholine reveal how mutation of Asp-128 disrupts a

274 e of PsaA in complex with both galactose and phosphocholine reveals separate receptor binding sites t

275 ry lipid mixtures (1,2-dioleoyl-sn-glycero-3-phosphocholine/sphingomyelin/cholesterol) into liquid-di

276 We used phosphocholine spin labels on the lipid headgroup and di

277 trations of the alkaline Pi-pool and glycero-phosphocholine, suggesting the possibility of using high

278 ethanolamine, glucose, lactate, myoinositol, phosphocholine, sylloinositol, and valine showed statist

279 oline kinase alpha, an enzyme that catalyzes phosphocholine synthesis and was strikingly increased in

280 )ben zyl]oxy]carbonyl]nonanoyl]-sn-glycero-3-phosphocholine, the association of PMCA to actin produce

281 atch produced by a 1,2-dioleoyl-sn-glycero-3-phosphocholine thicker bilayer could be a structural fou

282 hylation pathway, which forms the head-group phosphocholine through the triple methylation of phospho

283 )ben zyl]oxy]carbonyl]nonanoyl]-sn-glycero-3-phosphocholine to the protein.

284 Specifically, 1,2-dimyristoyl-sn-glycero-3-phosphocholine transfer and flip-flop kinetics display l

285 VPC) or 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine, two oxidized phospholipids (oxPLs) that

286 To install the phosphocholine unit, a highly effective phosphocholine d

287 nal channel domain that mediated glucose and phosphocholine uptake across the outer membrane in an M.

288 ate functional nanopores in DIBs composed of phosphocholine using the protein alpha-hemolysin (alphaH

289 a-barrel) and two different detergent types (phosphocholines versus an alkyl sugar) with respect to p

290 ipid domains in 1,2-dimyristoyl-sn-glycero-3-phosphocholine vesicles is observed to occur in as fast

291 -phosphocholine/1,2-dimyristoyl-sn-glycero-3-phosphocholine vesicles was quantified from proton NMR m

292 citric acid and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine was linear following intraperitoneal admi

293 In bicellar systems comprising 14-C phosphocholines, we observe that protein-lipid interacti

294 to the pneumococcal polysaccharide component phosphocholine were significantly lower in A181E-heteroz

295 e], and 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine, were identified in the extracted lipid p

296 lipid in eukaryotic cells, into ceramide and phosphocholine, which are then utilized by Mtb as carbon

297 idylcholine found in MV membranes to produce phosphocholine, which PHOSPHO1 can hydrolyze to liberate

298 here are no other reports on interactions of phosphocholine with nAChR.

299 ontaining either a carbonate or zwitterionic phosphocholine within the polymer backbone.

300 ning POPC (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine) yielded an equilibrium dissociation cons