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1 53924, which causes the substitution R70C in phospholemman.
2  in myocytes lacking the regulatory protein, phospholemman.
3 tion alters the interaction of Na/K-pump and phospholemman.
4 ar to the Na(+),K(+)-ATPase regulator, FXYD1/Phospholemman.
5               We observed down-regulation of phospholemman (a phosphoprotein associated with anion ch
6     We previously identified FXYD1 (encoding phospholemman; a protein containing the motif phenylalan
7                             We conclude that phospholemman and Na/K-pump are in very close proximity
8 r inward-rectifier Cl- channels, e.g. ClC-2, phospholemman and the channel in Xenopus oocytes.
9 y of small membrane proteins, represented by phospholemman and the gamma subunit of Na,K-ATPase, was
10 t (CFP/YFP) fusion proteins of Na/K pump and phospholemman and whether phospholemman phosphorylation
11                                              Phospholemman antibodies precipitated all three Na,K-ATP
12 pitation and functional studies suggest that phospholemman associates with the Na/K-pump (NKA) and me
13 PKA targets, such as phospholamban at Ser16, phospholemman at Ser68 and cardiac myosin-binding protei
14  of the Na(+),K(+)-ATPase modulating protein phospholemman at serine residue 63 (S63 PLM).
15 Much like phospholamban regulation of SERCA, phospholemman exists as both a sodium pump inhibiting mo
16  not NKA-alpha1 was coupled to a decrease in phospholemman expression and phosphorylation, which woul
17                                 Furthermore, phospholemman (FXYD1) inhibits pump function without sig
18                                              Phospholemman (FXYD1) is a homolog of the Na,K-ATPase ga
19                                              Phospholemman (FXYD1) is a single-transmembrane protein
20 ed variants of the transmembrane lipoprotein phospholemman (FXYD1).
21 dies, phospholemman knock-in mice (PLM(3SA); phospholemman [FXYD1] in which the 3 phosphorylation sit
22 sure (BP), the role of its accessory protein phospholemman has not been characterized.
23  isoform and consistent with the presence of phospholemman in both neurons and glia.
24 hed human genomic databases for mutations in phospholemman in the region of the phosphorylation sites
25                            Here we show that phospholemman is highly expressed in selected structures
26 8, and 69 are mutated to alanines), in which phospholemman is rendered unphosphorylatable, were used
27                            In mouse studies, phospholemman knock-in mice (PLM(3SA); phospholemman [FX
28 t nearly abolished when co-expressing excess phospholemman lacking YFP.
29 e-spanning membrane proteins such as cardiac phospholemman, Mat-8 and renal CHIF, large ion conductan
30 sphorylation signature associates with other phospholemman molecules but not with the pump.
31 ospholemman phosphorylation, consistent with phospholemman multimerization.
32                                              Phospholemman oligomers exist in cardiac muscle.
33 olubilized crude membranes using either anti-phospholemman or anti-Na,K-ATPase antibodies.
34 without any differences in membrane markers (phospholemman, phosphalamban, dihydropyridine-binding co
35 s of Na/K pump and phospholemman and whether phospholemman phosphorylation alters such FRET.
36  very close proximity (FRET occurs) and that phospholemman phosphorylation alters the interaction of
37                                              Phospholemman phosphorylation at Ser63 and Ser68 limited
38 ic kidney cells, the R70C mutation prevented phospholemman phosphorylation at Ser68.
39                                Prevention of phospholemman phosphorylation in the PLM(3SA) mouse prof
40  These studies demonstrate the importance of phospholemman phosphorylation in the regulation of vascu
41 horylatable, were used to assess the role of phospholemman phosphorylation in vitro in aortic and mes
42                             This agreed with phospholemman phosphorylation measurements: by protein k
43 f this study was to test the hypothesis that phospholemman phosphorylation regulates vascular tone in
44 an embryonic kidney cells, and its effect on phospholemman phosphorylation was determined using Weste
45  photobleach), and this FRET was enhanced by phospholemman phosphorylation, consistent with phosphole
46 nt experimental approaches demonstrated that phospholemman physically associated with the Na,K-ATPase
47                                    In heart, phospholemman (PLM) inhibits NKA activity by reducing it
48                                              Phospholemman (PLM) is a member of the FXYD ('fix-it') f
49                                              Phospholemman (PLM) is a small (72-amino acid) transmemb
50                                              Phospholemman (PLM) is a small transmembrane cardiac pro
51 e NKA-associated small transmembrane protein phospholemman (PLM) mediates beta-adrenergic-induced NKA
52                                              Phospholemman (PLM) or FXYD1 is a major cardiac myocyte
53                                              Phospholemman (PLM) phosphorylation mediates enhanced Na
54                   The cardiac phosphoprotein phospholemman (PLM) regulates the cardiac sodium pump, a
55                                      Because phospholemman (PLM) regulates the Na(+)/K(+) pump (NKA)
56                      The sarcolemmal protein phospholemman (PLM) was found associated with the Na/K A
57 afficking of two FXYD family members, FXYD1 (phospholemman (PLM)) and FXYD7.
58         We have demonstrated previously that phospholemman (PLM), a 15-kDa integral sarcolemmal phosp
59                           Here, we show that phospholemman (PLM), a 15-kDa integral sarcolemmal phosp
60  Previous reports have demonstrated that the phospholemman (PLM), a 72-residue plasma-membrane protei
61                                              Phospholemman (PLM), a major membrane substrate for phos
62                           We have found that phospholemman (PLM), a member of the FXYD family and reg
63                                              Phospholemman (PLM), a member of the FXYD family of prot
64                                              Phospholemman (PLM), a member of the FXYD family of smal
65 arts) expression of Na/K-ATPase isoforms and phospholemman (PLM), a putative Na/K-ATPase regulatory s
66 eased, the palmitoylated regulatory protein, phospholemman (PLM), and the cardiac Na/Ca exchanger (NC
67                                              Phospholemman (PLM), the principal quantitative sarcolem
68                                              Phospholemman (PLM), the principal sarcolemmal substrate
69 eraction with a small transmembrane protein, phospholemman (PLM).
70                      Phospholamban (PLB) and phospholemman (PLM, also called FXYD1) are small transme
71 a key modulatory partner is the FXYD protein phospholemman (PLM, FXYD1), but the stoichiometry of the
72                     Serine 68-phosphorylated phospholemman (pSer-68-PLM) inhibits NCX1 activity.
73  Antibodies against the C-terminal domain of phospholemman reduced Na,K-ATPase activity in vitro with
74                                              Phospholemman regulates the plasmalemmal sodium pump in
75                     In aging wild-type mice, phospholemman was hypophosphorylated, and this correlate
76                                              Phospholemman was particularly enriched in choroid plexu
77        In cardiac muscle, a subpopulation of phospholemman with a unique phosphorylation signature as