ライフサイエンスコーパス: phosphoribosyltransferase

1 purine recycling enzyme hypoxanthine-guanine phosphoribosyltransferase.

2 ounts for the allosteric inhibition of MtATP-phosphoribosyltransferase.

3 eficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase.

4 D biosynthetic enzymes, namely, nicotinamide phosphoribosyltransferase.

5 r catalysis in one of these enzymes, adenine phosphoribosyltransferase.

6 at the site of the upt gene encoding uracil phosphoribosyltransferase.

7 city is funnelled exclusively through uracil phosphoribosyltransferase.

8 -glucuronidase and cytosine deaminase/uracil phosphoribosyltransferase.

9 lic factors rather by the specificity of the phosphoribosyltransferase.

10 ovo pathway gene, nadC, encoding quinolinate phosphoribosyltransferase.

11 as a fluorescent substrate for yeast adenine phosphoribosyltransferase.

12 lytically poised reaction complex for type I phosphoribosyltransferases.

13 cores, an element common to all known purine phosphoribosyltransferases.

14 a structural theme found in all known purine phosphoribosyltransferases.

15 dehydrogenase (GAPDH), hypoxanthine-guanine phosphoribosyltransferase 1 (HPRT1), DNA-directed RNA po

16 nished by adding nicotinic acid (NA) in a NA phosphoribosyltransferase 1 (NAPRT1)-dependent manner, b

17 target HPRT1, the gene encoding hypoxanthine phosphoribosyltransferase-1 (HPRT1), and POU5F1, the gen

18 gulated (thymidine kinase, 2.9-fold; orotate phosphoribosyltransferase, 2.3-fold; uridine monophospha

19 for the specificity of hypoxanthine-guanine phosphoribosyltransferase, a key enzyme in the purine sa

20 e generated mice overexpressing nicotinamide phosphoribosyltransferase, a rate-limiting enzyme for NA

21 1778 is a specific inhibitor of nicotinamide phosphoribosyltransferase, a rate-limiting enzyme requir

22 d characterized physically, for their uracil phosphoribosyltransferase activity and for their ability

23 ing, bioinformatic analyses, and an assay of phosphoribosyltransferase activity in Mycobacterium smeg

24 Indeed, the quinolinate (Qa) phosphoribosyltransferase activity of NadC from S. pyoge

25 B. burgdorferi showed low but detectable phosphoribosyltransferase activity with hypoxanthine eve

26 lation of pyr genes in vivo and their uracil phosphoribosyltransferase activity, which is catalyzed b

27 enhancing factor, known to have nicotinamide phosphoribosyltransferase activity.

28 show that a novel mycobacterial mannosylated phosphoribosyltransferase acts as a virulence and immuno

29 ccompanied by suppressed SIRT1, nicotinamide phosphoribosyltransferase, AGE receptor 1, and PPARgamma

30 hose without renal-risk variants; nicotinate phosphoribosyltransferase also displayed gene expression

31 circadian expression of NAMPT (nicotinamide phosphoribosyltransferase), an enzyme that provides a ra

32 rasite lacking hypoxanthine-xanthine-guanine phosphoribosyltransferase and a T. gondii cDNA library.

33 ities, Km values, and Vmax values of adenine phosphoribosyltransferase and of hypoxanthine phosphorib

34 The last two enzymes of the pathway, orotate phosphoribosyltransferase and orotidine-5-monophosphate

35 g MTA from the polyamine pathway via adenine phosphoribosyltransferase and recycling MTR to methionin

36 to FK866-mediated inhibition of nicotinamide phosphoribosyltransferase and stimulates glycolysis in c

37 Two of these, uridine kinase-uracil phosphoribosyltransferase and thymidine kinase, are uniq

38 is encoded on an operon with nicotinic acid phosphoribosyltransferase and, in some Pseudomonads, wit

39 Purine and pyrimidine phosphoribosyltransferases and nucleoside N-ribosyl hydr

40 SirT1, nicotinamide phosphoribosyltransferase, and NAD may, therefore, provi

41 Bacillus subtilis xpt gene encoding xanthine phosphoribosyltransferase, and the S-adenosyl-methionine

42 ily of salvage and biosynthetic enzymes, the phosphoribosyltransferases, and catalyzes the transfer o

43 Using the adenine phosphoribosyltransferase (APRT(+)) --> APRT(-) forward

44 he contrary, we found no evidence of adenine phosphoribosyltransferase (APRT) activity when parasites

45 major parallel pathways mediated by adenine phosphoribosyltransferase (APRT) and guanine phosphoribo

46 Adenine phosphoribosyltransferase (APRT) deficiency is a rare, h

47 Adenine phosphoribosyltransferase (APRT) deficiency is a rare, h

48 ed and nontranscribed strands of the adenine phosphoribosyltransferase (APRT) gene in Chinese hamster

49 ations in the second intron of the adenosine phosphoribosyltransferase (APRT) gene in Chinese hamster

50 lification and overexpression of the adenine phosphoribosyltransferase (APRT) gene.

51 the CpG island upstream of the mouse adenine phosphoribosyltransferase (Aprt) gene.

52 nation between direct repeats at the adenine phosphoribosyltransferase (APRT) locus in ERCC1-deficien

53 iciently repaired in both strands of adenine phosphoribosyltransferase (APRT) locus, in either a tran

54 Knockdown for adenine phosphoribosyltransferase (APRT) or nicotinamide phospho

55 Adenine phosphoribosyltransferase (APRT, EC 2.4.2.7) catalyzes t

56 The adenine phosphoribosyltransferase (APRTase) from Giardia lamblia

57 Adenine phosphoribosyltransferase (APRTase) is a widely distribu

58 and relies primarily on adenine and guanine phosphoribosyltransferases (APRTase and GPRTase) constit

59 Here, we developed an adenine phosphoribosyltransferase (APT)-based RNAi technology (A

60 ltered expression of a gene encoding adenine phosphoribosyltransferase (APT1), an enzyme that convert

61 sis has shown that the anthranilate synthase-phosphoribosyltransferase (AS-PRT) enzyme complex, invol

62 Phosphoribosyltransferase assays revealed that, in gener

63 ATP-phosphoribosyltransferase (ATP-PRT) is a hexameric enzym

64 ATP-phosphoribosyltransferase (ATP-PRT), as the first enzyme

65 ATP-phosphoribosyltransferase (ATP-PRT), the first enzyme of

66 osteric domain.Active and inactive state ATP-phosphoribosyltransferases (ATP-PRTs) are believed to ha

67 of biomass in E. coli were identified as ATP phosphoribosyltransferase, ATP synthase, methylene-tetra

68 Unlike all known phosphoribosyltransferases, beta-RFA-P synthase catalyze

69 cleotide binding to PyrR is similar to other phosphoribosyltransferases, but Mg2+ binding differs.

70 Purine phosphoribosyltransferases catalyze the Mg2+ -dependent

71 MtATP-phosphoribosyltransferase catalyzes the first and commit

72 Hereditary deficiency of adenine phosphoribosyltransferase causes 2,8-dihydroxyadenine (2

73 and activity of a cytosine deaminase-uracil phosphoribosyltransferase (CD-UPRT) fusion enzyme expres

74 diac-specific overexpression of nicotinamide phosphoribosyltransferase (cNAMPT) as examples.

75 he hydroxybenzimidazole synthase BzaAB/BzaF, phosphoribosyltransferase CobT, and three methyltransfer

76 void of NaMN:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase (CobT) activity was used to is

77 otide (NaMN):5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase (CobT) from Salmonella enteric

78 onucleotide (NaMN):5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enteric

79 ized by nicotinate mononucleotide (NaMN):DMB phosphoribosyltransferases (CobT in Salmonella enterica)

80 nthetic enzyme complex anthranilate synthase-phosphoribosyltransferase, composed of the TrpD and TrpE

81 The structure represents a new fold for a phosphoribosyltransferase, consisting of three continuou

82 reased dosage of NPT1, encoding a nicotinate phosphoribosyltransferase critical for the NAD(+) salvag

83 ft loss in patients with undiagnosed adenine phosphoribosyltransferase deficiency and the need for im

84 ls led to accumulation of cells with adenine phosphoribosyltransferase deficiency and UPD.

85 Adenine phosphoribosyltransferase deficiency is a rare autosomal

86 Patients with adenine phosphoribosyltransferase deficiency showed similar hist

87 We describe a patient with adenine phosphoribosyltransferase deficiency who was diagnosed d

88 eatures associated with hypoxanthine-guanine phosphoribosyltransferase deficiency.

89 agnosis of all forms of hypoxanthine-guanine phosphoribosyltransferase deficiency.

90 phoribosyltransferase (APRT) or nicotinamide phosphoribosyltransferase did not change the antiviral a

91 fic noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, does not alter glycolysis or

92 residues required for the reorganization of phosphoribosyltransferase domain "flexible loop" that le

93 nonucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase (EC 2.4.2.21) enzyme that synt

94 a protein called extracellular nicotinamide phosphoribosyltransferase (eNampt; also known as pre-B c

95 identified a novel mannosylated glycoprotein phosphoribosyltransferase, encoded by Rv3242c from M. tu

96 The reversible adenine phosphoribosyltransferase enzyme (APRT) is essential for

97 a decrease in expression of the nicotinamide phosphoribosyltransferase enzyme that recycles the nicot

98 NAD+ levels by interfering with nicotinamide phosphoribosyltransferase expression rendered tumor cell

99 similarities to other members of the type 1 phosphoribosyltransferase family but do not reveal the s

100 yeast fusion gene, cytosine deaminase/uracil phosphoribosyltransferase (FCU).

101 led that the functional domain has a type II phosphoribosyltransferase fold that may be a common arch

102 ified with the micronucleus and hypoxanthine phosphoribosyltransferase forward mutation assays.

103 Guanine phosphoribosyltransferase from Giardia lamblia, a key en

104 termined the crystal structure of nicotinate phosphoribosyltransferase from Themoplasma acidophilum (

105 urification of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Thermus thermophilus (TtH

106 Orotate phosphoribosyltransferases from Plasmodium falciparum an

107 For the X-linked human hypoxanthine phosphoribosyltransferase gene (HPRT), this difference i

108 geted correction of a defective hypoxanthine phosphoribosyltransferase gene in hematopoietic progenit

109 black patients revealed that the nicotinate phosphoribosyltransferase gene, responsible for NAD bios

110 th and mutations at the hypoxanthine-guanine phosphoribosyltransferase gene.

111 le mutation rate of the hypoxanthine-guanine phosphoribosyltransferase gene.

112 Of the two phosphoribosyltransferase genes found in the H. pylori g

113 By investigating candidate phosphoribosyltransferase genes in the genome, we determ

114 phosphoribosyltransferase (APRT) and guanine phosphoribosyltransferase (GPRT) that constitute the pri

115 Hypoxanthine-guanine-(xanthine) phosphoribosyltransferase (HG(X)PRT) is crucial for the

116 Hypoxanthine-guanine-[xanthine] phosphoribosyltransferase (HG[X]PRT) is considered an im

117 ood inhibitors of human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and Plasmodium falcipa

118 rines primarily through hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and xanthine phosphori

119 demonstrate that human hypoxanthine guanine phosphoribosyltransferase (HGPRT) converts T-705 into it

120 Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is the key enzyme in p

121 y was determined at the hypoxanthine-guanine phosphoribosyltransferase (HGPRT) locus.

122 urine recycling enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt).

123 purine salvage enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGPRT).

124 t salvage of guanine by hypoxanthine-guanine phosphoribosyltransferase (HGPRT).

125 h LND and its variants (hypoxanthine-guanine phosphoribosyltransferase [HGprt]-related neurological d

126 phosphorylase (PNP) and hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) catalyze N-ribosidi

127 The hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRTase), a type I PRTase,

128 ine biosynthetic enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) cause the intractable n

129 toid cells in the human hypoxanthine-guanine-phosphoribosyltransferase (HPRT) gene and compared with

130 mouse ES cells having a mutant hypoxanthine phosphoribosyltransferase (Hprt) gene and grown on feede

131 moter and exon 1 of the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene in the mouse and h

132 e enzyme designed to target the hypoxanthine phosphoribosyltransferase (HPRT) gene located on human c

133 factor (VWF) and Flt-1, to the hypoxanthine phosphoribosyltransferase (Hprt) gene locus.

134 geted cells by co-targeting the hypoxanthine phosphoribosyltransferase (HPRT) gene.

135 functional, the complete human hypoxanthine phosphoribosyltransferase (HPRT) locus contained within

136 The hypoxanthine phosphoribosyltransferase (Hprt) locus has been shown to

137 tion frequencies at the hypoxanthine guanine phosphoribosyltransferase (HPRT) locus in diploid human

138 with cRSS sites at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in peripheral T c

139 somatic mutation events at the hypoxanthine phosphoribosyltransferase (HPRT) locus in peripheral T l

140 We found that hypoxanthine phosphoribosyltransferase (HPRT) mutation frequencies we

141 on the frequency of spontaneous hypoxanthine phosphoribosyltransferase (HPRT) mutations that can be d

142 sed by mutations of the hypoxanthine guanine phosphoribosyltransferase (HPRT) purine biosynthesis gen

143 Here we present the hypoxanthine-guanine phosphoribosyltransferase (HPRT) reporter gene mutationa

144 through the activity of hypoxanthine-guanine phosphoribosyltransferase (HPRT) to supply the cell with

145 romosomal disease gene encoding hypoxanthine phosphoribosyltransferase (HPRT), we monitor the relativ

146 mutations (Mfs) at the hypoxanthine-guanine phosphoribosyltransferase (HPRT)-reporter gene in childr

147 oribosyltransferase (XGPRT) and hypoxanthine phosphoribosyltransferase (HPRT).

148 e purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT).

149 hromosome-linked enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT).

150 Hypoxanthine phosphoribosyltransferase (HPRT1) is a key enzyme in the

151 riant aspartic acid (Asp137) in hypoxanthine phosphoribosyltransferases (HPRTs) was examined by site-

152 salvage 6-oxopurines, including hypoxanthine phosphoribosyltransferases (HPRTs), are potential target

153 enes included those for hypoxanthine-guanine phosphoribosyltransferase (hpt), adenylosuccinate syntha

154 by the enzymes hypoxanthine-xanthine-guanine phosphoribosyltransferase (HXGPRT) and adenosine kinase

155 n of T. gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase (HXGPRT) in stable transgenic

156 Conversely, mice lacking nicotinamide phosphoribosyltransferase in hepatocytes exhibited impai

157 previously unrecognized role for a conserved phosphoribosyltransferase in NAD(+) biosynthesis.

158 f transcriptional repression of nicotinamide phosphoribosyltransferase in the NAD(+) salvage pathway.

159 tween the two families of ATP-PRTs and among phosphoribosyltransferases in general, we determined the

160 Two phosphoribosyltransferases in the purine salvage pathway

161 imiting enzyme in this pathway, nicotinamide phosphoribosyltransferase, increases total and mitochond

162 g [NAD(+)](i) by FK866-mediated nicotinamide phosphoribosyltransferase inhibition decreased the mitog

163 7.5 MBq, intravenously) or the nicotineamide phosphoribosyltransferase inhibitor GMX1778 (100 mg/kg/w

164 he slr0788 gene is a nicotinamide-preferring phosphoribosyltransferase involved in the first step of

165 idence indicates that PBEF is a nicotinamide phosphoribosyltransferase involved in the mammalian salv

166 l filtration experiments indicate that MtATP-phosphoribosyltransferase is a hexamer in solution, in t

167 MsmRv3242c infection models, we proved that phosphoribosyltransferase is involved in mycobacterial v

168 -ribose-1-diphosphate:decaprenyl-phosphate 5-phosphoribosyltransferase is known to be essential for t

169 Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is a protein with several sug

170 nalysis has authenticated L. donovani uracil phosphoribosyltransferase (LdUPRT), an enzyme not found

171 the NAD salvage pathway enzyme nicotinamide phosphoribosyltransferase led to changes in NAD levels,

172 mbles bacterial ComF proteins and includes a phosphoribosyltransferase-like module.

173 alpha or Yalpha and the hypoxanthine guanine phosphoribosyltransferase locus (HPRT1).

174 eporter gene 5' of the X-linked hypoxanthine phosphoribosyltransferase locus in mouse embryonic stem

175 (Tg; inserted into the hypoxanthine-guanine phosphoribosyltransferase locus) that enables inducible

176 nock-in approach at the hypoxanthine-guanine phosphoribosyltransferase locus, we generated a transgen

177 potential new target is hypoxanthine-guanine phosphoribosyltransferase (MtHGPRT), a key enzyme of the

178 In mammals, nicotinamide phosphoribosyltransferase (NAMPT) and nicotinamide monon

179 he NAD biosynthesis mediated by nicotinamide phosphoribosyltransferase (Nampt) and nicotinamide/nicot

180 pharmacological inhibitors for nicotinamide phosphoribosyltransferase (NAMPT) are promising therapeu

181 ss of cancer drugs that targets nicotinamide phosphoribosyltransferase (NAMPT) as a new strategy to i

182 Nicotinamide phosphoribosyltransferase (NAMPT) catalyzes the first ra

183 taining inhibitors of the human nicotinamide phosphoribosyltransferase (NAMPT) enzyme were identified

184 own-regulated expression of the nicotinamide phosphoribosyltransferase (Nampt) gene encoding the rate

185 Nicotinamide phosphoribosyltransferase (NAMPT) has been extensively s

186 enine dinucleotide (NAD(+)) via nicotinamide phosphoribosyltransferase (Nampt) has emerged as a media

187 We recently demonstrated that Nicotinamide phosphoribosyltransferase (Nampt) inhibition depletes in

188 Here, we show that nicotinamide phosphoribosyltransferase (NAMPT) inhibition suppresses

189 ion between PPM1D mutations and nicotinamide phosphoribosyltransferase (NAMPT) inhibition.

190 NAD+ depletion via concomitant nicotinamide phosphoribosyltransferase (NAMPT) inhibition.

191 With the example of a novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitor, we demonstr

192 Nicotinamide phosphoribosyltransferase (NAMPT) is a key enzyme involv

193 Nicotinamide phosphoribosyltransferase (Nampt) is a promising antican

194 Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enz

195 Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enz

196 Nicotinamide phosphoribosyltransferase (Nampt) is a rate-limiting enz

197 Nicotinamide phosphoribosyltransferase (NAMPT) is highly evolved to c

198 Nicotinamide phosphoribosyltransferase (NAMPT) is located in both the

199 e NAD(+) salvage pathway, where nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting e

200 Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting e

201 Nicotinamide phosphoribosyltransferase (Nampt) is the rate-limiting e

202 Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting e

203 and analyzed adipocyte-specific nicotinamide phosphoribosyltransferase (Nampt) knockout (ANKO) and br

204 cell nuclear antigen (PCNA) and nicotinamide phosphoribosyltransferase (Nampt) levels.

205 s of SIRT1 protein, NAD(+), and nicotinamide-phosphoribosyltransferase (NAMPT) mRNA in several cell t

206 , we report that stimulation of nicotinamide phosphoribosyltransferase (NAMPT) produced robust neurop

207 NR supplementation decreases nicotinamide phosphoribosyltransferase (NAMPT) protein abundance in s

208 d compounds in complex with the nicotinamide phosphoribosyltransferase (Nampt) protein were utilized

209 the NAD(+)-synthesizing enzyme nicotinamide phosphoribosyltransferase (NAMPT) reduces liver NAD(+) l

210 Human nicotinamide phosphoribosyltransferase (NAMPT) replenishes the NAD po

211 One approach is activation of nicotinamide phosphoribosyltransferase (NAMPT) to increase production

212 Nicotinamide phosphoribosyltransferase (NAMPT) upregulation in human

213 on of NAD+ biosynthesis enzyme, nicotinamide phosphoribosyltransferase (NAMPT) via myocyte enhancer f

214 lony-enhancing factor (PBEF) or nicotinamide phosphoribosyltransferase (Nampt)) is a pleiotropic medi

215 ere raised by observations that nicotinamide phosphoribosyltransferase (NAMPT), a key enzyme in mamma

216 de increase their expression of nicotinamide phosphoribosyltransferase (NAMPT), a key enzyme in NAD(+

217 Nicotinamide phosphoribosyltransferase (NAMPT), an adipokine that pla

218 Protein levels of nicotinamide phosphoribosyltransferase (NAMPT), an essential NAD(+) b

219 nucleotide (NAD+) biosynthesis, nicotinamide phosphoribosyltransferase (NAMPT), and levels of NAD+ di

220 nhibitors, specifically against nicotinamide phosphoribosyltransferase (NAMPT), as preclinical studie

221 bition with FK866 of the enzyme nicotinamide phosphoribosyltransferase (NAMPT), catalyzing the first

222 adenylyltransferase (NMNAT) and nicotinamide phosphoribosyltransferase (NAMPT), mainly replenishes NA

223 gnificant decrease of SIRT1 and nicotinamide phosphoribosyltransferase (NAMPT), SIRT1 activity and ph

224 e NAD(+) salvage pathway enzyme nicotinamide phosphoribosyltransferase (NAMPT), synergizes with MMS t

225 We demonstrate that nicotinamide phosphoribosyltransferase (Nampt), the equivalent enzyme

226 is derivative was found to bind nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enz

227 show that levels of NAD(+) and nicotinamide phosphoribosyltransferase (Nampt), the rate-limiting enz

228 d pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enz

229 sustained endotoxin tolerance, nicotinamide phosphoribosyltransferase (Nampt), the rate-limiting enz

230 ates the myeloid cell levels of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enz

231 Here, we show that nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enz

232 Here, we report nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting ste

233 tment reduced the expression of nicotinamide phosphoribosyltransferase (NAMPT), thus limiting IDH2 ac

234 and we found that inhibition of nicotinamide phosphoribosyltransferase (Nampt), which synthesizes sub

235 om nicotinamide is performed by nicotinamide phosphoribosyltransferase (Nampt).

236 ethyl)benzamide (CB38065, 1) is nicotinamide phosphoribosyltransferase (Nampt).

237 e NAD(+) salvage pathway enzyme nicotinamide phosphoribosyltransferase (NAMPT).

238 ion on lysine 74 and 78 via the nicotinamide phosphoribosyltransferase (NAMPT)/sirtuin 2 (SIRT2) path

239 synthesis to exclusive usage of nicotinamide phosphoribosyltransferase (NamPT); 2) the occurrence of

240 Human nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12) catalyzes

241 tracellular enzymatic activity (nicotinamide phosphoribosyltransferase, Nampt) leading to NAD synthes

242 wly described endolysosomal activities of NA phosphoribosyltransferase (NAPRT) and NMN adenyltransfer

243 motes epigenetic silencing of nicotinic acid phosphoribosyltransferase (NAPRT), a key gene involved i

244 re, we show the gene encoding nicotinic acid phosphoribosyltransferase (NAPRT), a second NAD(+)-produ

245 g the NAD+ salvage pathway enzyme nicotinate phosphoribosyltransferase (Naprt1), sensitizing to NAD+

246 rate by the NAD(+) salvage pathway enzyme NA phosphoribosyltransferase (Npt1).

247 ic pathway including NtPMT1a and quinolinate phosphoribosyltransferase (NtQPT2), and lowers nicotine

248 needed for drugs targeting the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi, etiologi

249 izing effects of inhibition of nicotineamide phosphoribosyltransferase on (177)Lu-DOTATATE treatment

250 (UMP) biosynthesis are catalyzed by orotate phosphoribosyltransferase (OPRT) and orotidine 5'-monoph

251 Orotate phosphoribosyltransferase (OPRT) is an indispensible com

252 Orotate phosphoribosyltransferases (OPRT) catalyze the formation

253 kinetic mechanism ascribed to yeast orotate phosphoribosyltransferase (OPRTase) has been shown to be

254 Orotate phosphoribosyltransferase (OPRTase, EC 2.4.2.10) catalyz

255 Orotate phosphoribosyltransferases (OPRTs) form and break the N-

256 Nicotinamide phosphoribosyltransferase overexpressing mice were mildl

257 alciparum (Pf) hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT).

258 Two putative nicotinic acid phosphoribosyltransferases, PncB1 (Rv1330c) and PncB2 (R

259 both nicotinic acid and quinolinic acid (QA) phosphoribosyltransferases (PRTase) despite low sequence

260 Unlike most PRT proteins, which are phosphoribosyltransferases (PRTases), PurR lacks catalyt

261 m (Pf) and Plasmodium vivax (Pv) 6-oxopurine phosphoribosyltransferases (PRTs).

262 Quinolinate phosphoribosyltransferase (QAPRTase, EC 2.4.2.19) cataly

263 Quinolinate phosphoribosyltransferase (QAPRTase, EC 2.4.2.19) cataly

264 Quinolinic acid phosphoribosyltransferase (QAPRTase, EC 2.4.2.19) forms

265 lastic astrocytes, expressed quinolinic acid phosphoribosyltransferase (QPRT) to use quinolinic acid

266 Because a required quinolinic acid phosphoribosyltransferase (QPRTase) is not encoded in it

267 R, B. caldolyticus PyrR catalyzes the uracil phosphoribosyltransferase reaction but with maximal acti

268 ysis, demonstrate unique overlapping ATP and phosphoribosyltransferase sites, and establish reaction

269 ctural neighbors to APRTases are the orotate phosphoribosyltransferases, suggesting different paths o

270 er reports of Ping Pong kinetics for various phosphoribosyltransferases that do not form the phosphor

271 nly in muscle by overexpressing nicotinamide phosphoribosyltransferase, the rate-limiting enzyme in t

272 . maripaludis hpt gene encoding hypoxanthine phosphoribosyltransferase to confer sensitivity to the b

273 Moreover, targeting nicotinamide phosphoribosyltransferase to the mitochondria also enhan

274 These novel phosphoribosyltransferase transition states are similar

275 how high structural homology to anthranilate phosphoribosyltransferase (TrpD) and nucleoside phosphor

276 was reconstituted in vitro with anthranilate phosphoribosyltransferase (TrpD), threonine dehydratase

277 ned that the conserved uridine monophosphate phosphoribosyltransferase (UMPS), which acts in pyrimidi

278 Uracil phosphoribosyltransferase (UPP) catalyzes the initial st

279 tively encode uridine kinase (UK) and uracil phosphoribosyltransferase (UPRT) bifunctional enzymes we

280 e combination of spatially restricted uracil phosphoribosyltransferase (UPRT) expression with 4-thiou

281 Uracil phosphoribosyltransferase (UPRT) is a member of a large

282 Uracil phosphoribosyltransferase (UPRT) is a pyrimidine salvage

283 Cre-induced expression of uracil phosphoribosyltransferase (UPRT) provides spatial specif

284 l (TU) in cells expressing transgenic uracil phosphoribosyltransferase (UPRT), a method known as TU-t

285 st enzyme in pyrimidine biosynthesis, uracil phosphoribosyltransferase (UPRT), a salvage enzyme, or b

286 mice that express cell-type-specific uracil phosphoribosyltransferase (UPRT), an enzyme required for

287 herichia coli cytosine deaminase (CD)/uracil phosphoribosyltransferase (UPRT).

288 PyrR also catalyzes the uracil phosphoribosyltransferase (UPRTase) reaction even though

289 ss I homologue) and HPRT (human hypoxanthine phosphoribosyltransferase), was accomplished.

290 uanosine deaminase, and hypoxanthine guanine phosphoribosyltransferase, we demonstrate that purine nu

291 hosphoribosyltransferase and of hypoxanthine phosphoribosyltransferase were the same in extracts from

292 lucuronidase and a cytosine deaminase/uracil phosphoribosyltransferase, which activate the prodrugs 9

293 63), in contrast to the hypoxanthine-guanine phosphoribosyltransferases, which use two Mg2+ ions; and

294 G. lamblia expresses an unusual purine phosphoribosyltransferase with a high specificity for gu

295 two purine salvage enzymes: xanthine-guanine phosphoribosyltransferase (XGPRT) and hypoxanthine phosp

296 phyla Firmicutes and Bacteroidetes, xanthine phosphoribosyltransferase (XPRT) is a purine salvage enz

297 sphoribosyl-transferase (HGPRT) and xanthine phosphoribosyltransferase (XPRT) using gene replacement

298 Recombinant LdPEX5 bound xanthine phosphoribosyltransferase (XPRT), a PTS-1 containing gly

299 osphoribosyltransferase (HGPRT) and xanthine phosphoribosyltransferase (XPRT).

300 9) mutants), yeast cytosine deaminase:uracil phosphoribosyltransferase (yCD:UPRT) and nitroreductase