ライフサイエンスコーパス: phosphotransfer

1 ich in most phytochromes direct differential phosphotransfer.

2 rdinates with Ser75, the residue involved in phosphotransfer.

3 ated with adenosine triphosphate binding and phosphotransfer.

4 n of domains in a state seemingly poised for phosphotransfer.

5 riant residues necessary for ATP binding and phosphotransfer.

6 ing the possibility of a histidine to serine phosphotransfer.

7 ed for dimerization, autophosphorylation and phosphotransfer.

8 various response regulators and the rates of phosphotransfer.

9 consistent with a dissociative mechanism of phosphotransfer.

10 c challenge is regulated by adenylate kinase phosphotransfer.

11 indeed contributes to the rapid kinetics of phosphotransfer.

12 P turnover rate or creatine kinase-catalyzed phosphotransfer.

13 CheA active site and properly positioned for phosphotransfer.

14 hilic histidine and activating glutamate for phosphotransfer.

15 te for the next stage; and 3) is involved in phosphotransfer.

16 s as product release may obscure the rate of phosphotransfer.

17 g the mutational change in measured in vitro phosphotransfer.

18 anism involving both inter- and intraprotein phosphotransfer.

19 -protein complex formation and in reversible phosphotransfer.

20 re not observed in histidine kinase-mediated phosphotransfer.

21 ric, as a proxy for increasing or decreasing phosphotransfer ability between TCS proteins.

22 ty, inhibition of adenylate kinase-catalyzed phosphotransfer abolished nuclear import.

23 of "split kinases" where the ATP binding and phosphotransfer activities of a conventional histidine k

24 vity, but is not essential for autokinase or phosphotransfer activities.

25 ophosphorylation activities as well as their phosphotransfer activities.

26 domains with impaired autophosphorylation or phosphotransfer activities.

27 is regulated by a fine equilibrium of three phosphotransfer activities: phosphorylation by the kinas

28 MP-dependent protein kinases (cGKs) suppress phosphotransfer activity at the catalytic cleft by compe

29 nscription to parent levels, suggesting that phosphotransfer activity of HPr and EI is important for

30 of regulation suggested that changes in the phosphotransfer activity of the sensor kinase, possibly

31 n the mitochondrial intermembrane space with phosphotransfer activity using mitochondrial ATP to rege

32 Mutants harboring HPr proteins altered for phosphotransfer activity were unable to restore atxA tra

33 of enzyme I (EIC) was shown to reconstitute phosphotransfer activity with recombinant N-terminal dom

34 TYK2 JH2 did not show phosphotransfer activity, but it binds ATP and the nucle

35 and show that although ULK4 has no apparent phosphotransfer activity, it can strongly bind ATP.

36 pseudokinases bind ATP, but only few retain phosphotransfer activity, leaving the functional role of

37 ne triphosphate production from PEP-mediated phosphotransfer, allowing for the high rate of glycolysi

38 However, hybrid kinases phosphotransfer almost exclusively to their covalently a

39 mplex is sufficient to stimulate the rate of phosphotransfer amongst the phosphorelay proteins in vit

40 Tar vs. H1-2-Tar) give opposite responses in phosphotransfer and cellular assays, despite similar bin

41 202A) and PhoP(D203A), had a reduced rate of phosphotransfer and could dimerize but could not bind DN

42 in A (67 residues) responsible for histidine phosphotransfer and dimerization, and domain B (161 resi

43 aining a phosphorylatable catalytic His with phosphotransfer and phosphatase activities over an effec

44 ponsible for dimerization of EnvZ, histidine phosphotransfer and phosphatase activities, and domain B

45 e multifunctional enzymes having autokinase, phosphotransfer and phosphatase activities, and most of

46 0F and the DHp domain, which is required for phosphotransfer and phosphatase activities.

47 us post-translational modification cascades, phosphotransfer and phosphorelay networks, T-cell kineti

48 s for the mechanisms of autophosphorylation, phosphotransfer and response-regulator dephosphorylation

49 Here, remodelling of phosphotransfer and substrate utilization networks in re

50 /-) hearts suggesting that rearrangements in phosphotransfer and substrate utilization networks provi

51 cillus subtilis, comprising snapshots of the phosphotransfer and the dephosphorylation reactions.

52 gulator via a series of autophosphorylation, phosphotransfer, and dephosphorylation reactions.

53 the tyrosine and primes it for the catalytic phosphotransfer, and it may lower the activation barrier

54 nsic modularity that separates signal input, phosphotransfer, and output response; this modularity ha

55 ome interactions thought to be important for phosphotransfer are missing in the ATP-containing struct

56 rk, we have used fluorescence anisotropy and phosphotransfer assays to examine OmpR interactions with

57 ieS and used them in autophosphorylation and phosphotransfer assays.

58 0 mM) and that the rate constant (kphos) for phosphotransfer at saturating phosphodonor concentration

59 nd transduce signals intracellularly through phosphotransfer between cognate histidine kinases (HKs)

60 Phosphotransfer between PhoR approximately P or PhoR(C30

61 o performed in vitro assays and showed rapid phosphotransfer between the CheA domain of FrzE and each

62 the domains responsible for recognition and phosphotransfer between the sensor histidine kinase and

63 enylate kinase-dependent inhibition involved phosphotransfer between two nucleotide diphosphates.

64 Inhibition of phosphotransfer by domain interfaces provides an explana

65 KDR kinase catalyzes phosphotransfer by formation of a ternary complex with A

66 it is possible for Ser75 to be activated for phosphotransfer by H-bonding to nearby residues rather t

67 f one IRAK4 monomer precisely positioned for phosphotransfer by its partner.

68 ve CFTR channel gating but is unsuitable for phosphotransfer by PKA, and CFTR mutants lacking phospho

69 Thus, although lack of AK1 phosphotransfer can be compensated in the absence of met

70 port, we assess the properties and potential phosphotransfer capability of a putative two-component r

71 drial CK have diminished PCr turnover, total phosphotransfer capacity and intracellular energetic com

72 Creatine kinase phosphotransfer, captured by 18O-assisted 31P NMR, coord

73 ansferase system (PTS) is a highly conserved phosphotransfer cascade that participates in the transpo

74 sor, which in turn relays a signal through a phosphotransfer cascade to the cognate cytoplasmic respo

75 ansferase system (PTS) is a highly conserved phosphotransfer cascade whose components modulate many c

76 subunits of protein kinase A, as well as the phosphotransfer catalytic activity of protein kinase A,

77 The phosphotransfer center is asymmetric, poised for dissoci

78 These phosphotransfer changes were associated with reduced lev

79 nase (AK), glycolytic and guanine nucleotide phosphotransfer circuits.

80 lation of the RR promotes the formation of a phosphotransfer-competent complex.

81 e deletion blunted vascular adenylate kinase phosphotransfer, compromised the contractility-coronary

82 es in the statistical goodness of fit of the phosphotransfer data to the kinetic model.

83 ified residues in the dimerization/histidine-phosphotransfer (DHp) domain of KinA that are functional

84 ene response sensor 1 dimerization histidine phosphotransfer (DHp) domains and the solution structure

85 e [comprising the dimerization and histidine phosphotransfer domain (DHp domain), connected to the AT

86 t signaling system, the histidine-containing phosphotransfer domain (the "P1" domain) of CheA receive

87 ly folding domains: the histidine-containing phosphotransfer domain and the ATP-binding kinase domain

88 reas phosphorylation of the histidine of the phosphotransfer domain by back reactions from Spo0F~P ap

89 a novel protein with a histidine-containing phosphotransfer domain homologous to the budding yeast Y

90 a small protein homologous to the histidine phosphotransfer domain of ArcB from E. coli, HptA.

91 elical region (residues 112 to 133) from the phosphotransfer domain of CheA interacts with CheZ and b

92 r-helix bundle serving as a dimerization and phosphotransfer domain, and domain B functions as the AT

93 action between Sda and the KinA dimerization/phosphotransfer domain.

94 ications for interactions with the substrate phosphotransfer domain.

95 lix bundle in the dimerization and histidine phosphotransfer domain.

96 ng) domain and a DHp (Dimerization Histidine phosphotransfer) domain for class I, or a CA domain and

97 a CA domain and an HPt (Histidine-containing Phosphotransfer) domain for class II histidine kinases.

98 Structures of various histidine phosphotransfer domains (HPt) complexed with their cogna

99 otypical family member, indicates that these phosphotransfer domains are likely to share a similar fo

100 uctive interaction between the catalytic and phosphotransfer domains of KinA.

101 contains input and output domains but lacks phosphotransfer domains typical of two-component systems

102 ance of this reaction in cardiac energetics, phosphotransfer dynamics were determined by [(18)O]phosp

103 onance spectroscopy to capture intracellular phosphotransfer dynamics.

104 rec functions both as a phosphate sink and a phosphotransfer element linking Hpt4-6 to Hpt2-3.

105 maining minor AK isoforms and the glycolytic phosphotransfer enzyme, 3-phosphoglycerate kinase.

106 ing that synapsins function as ATP-dependent phosphotransfer enzymes.

107 design a probe that enables detection of the phosphotransfer event; however, analysis of the phosphoh

108 Phosphotransfer experiments using isolated CheA-P showed

109 erfused hearts triggered a redistribution in phosphotransfer flux with significant increase in creati

110 l two-component systems (TCSs) use a central phosphotransfer for signaling; however, in vivo characte

111 residue in the receiver domain, usually via phosphotransfer from a cognate histidine kinase, stabili

112 ar response to an extracellular stimulus via phosphotransfer from a cognate sensor histidine kinase t

113 Two-component signal transduction based on phosphotransfer from a histidine protein kinase to a res

114 wn covalent phosphorylation and can catalyze phosphotransfer from a partner sensor kinase or autophos

115 We propose that the FlgR CTD prevents phosphotransfer from AcP so that FlgR is solely responsi

116 ate kinase enzyme (GK(enz)), which catalyzes phosphotransfer from ATP to GMP, evolved into the GK dom

117 ide and closed ones that enable catalysis of phosphotransfer from ATP to GMP.

118 of a glycine-rich motif that is critical for phosphotransfer from ATP.

119 ions downstream of these kinases to catalyze phosphotransfer from DivJ and PleC.

120 dent control of HnoK autophosphorylation and phosphotransfer from HnoK to three response regulators.

121 There was rapid phosphotransfer from Hpt2-6 to ChpArec and from Hpt3 to

122 HPr, its presence is essential for effective phosphotransfer from IIA(Glc) to the membrane-bound IIBC

123 ine-tuning role in determining the levels of phosphotransfer from its sensor kinase domain to the Ats

124 Sda also slows the rate of phosphotransfer from KinA approximately P to its target,

125 represents an enzyme intermediate just after phosphotransfer from PEP and before a conformational tra

126 n, 1.5, the overall equilibrium constant for phosphotransfer from PEP to HPr is 80, somewhat higher t

127 presence of PhoR require Mg(2+), the reverse phosphotransfer from PhoP approximately P to PhoR does n

128 he phosphoryl-protein intermediate(s) during phosphotransfer from PhoR approximately P to PhoP, which

129 vitro, CheY can be phosphorylated either by phosphotransfer from phospho-CheA or by acquiring a phos

130 The autophosphorylation of EnvZc and the phosphotransfer from phosphorylated EnvZc to OmpR were n

131 Phosphotransfer from RegB to RegA (overexpressed and pur

132 Analysis of phosphotransfer from small molecule phosphodonors has re

133 mation that is catalytically incompetent for phosphotransfer from small molecule phosphodonors.

134 osynthesis in Campylobacter jejuni stimulate phosphotransfer from the FlgS HK to the FlgR RR to promo

135 results indicate mechanistic differences in phosphotransfer from the kinase CheA versus that from sm

136 The specific Asp residue-dependent in vitro phosphotransfer from the kinase domain to the putative c

137 While it has been established that phosphotransfer from the kinase FrzE to the response reg

138 n the presence of ADP, which can mediate the phosphotransfer from the phospho-NDP kinase to the targe

139 n T + 2 likely reflect structural mimicry of phosphotransfer from the sensor kinase histidyl phosphat

140 Furthermore, phosphotransfer from the sensor kinase PhoR was enhanced

141 In the subsequent reactions, phosphotransfer from YPD1 to SSK1-R2 is very rapid (160

142 This phosphotransfer function renders adenylate kinase an imp

143 CheA-CheY phosphotransfer generates phospho-CheY, CheY-P.

144 yl group to RmFixJ in an oxygen-independent "phosphotransfer." Here we show that the mode of substrat

145 -directed mutagenesis of the two most likely phosphotransfer His residues (H121 and H168) did not abo

146 e Escherichia coli ArcB histidine-containing phosphotransfer (HPt) domain and the P1 domain of the Ch

147 rn-helix DNA binding domain, and a histidine phosphotransfer (HPt) domain.

148 chanism often involve a histidine-containing phosphotransfer (HPt) domain.

149 ains; six are canonical histidine-containing phosphotransfer (Hpt) domains and two have a threonine (

150 sor kinases to the Mpr1 histidine-containing phosphotransfer (HPt) protein and finally to the Mcs4 re

151 The histidine-containing phosphotransfer (HPt) protein YPD1 is an osmoregulatory

152 romyces cerevisiae, the histidine-containing phosphotransfer (HPt) protein YPD1 transfers phosphoryl

153 istidine kinase SLN1, a histidine-containing phosphotransfer (HPt) protein YPD1, and two response reg

154 st insight into the key step of MSP-mediated phosphotransfer in a eukaryotic system, the phosphorylat

155 , with an increased contribution to cellular phosphotransfer in heart failure.

156 recognition specificity and the fidelity of phosphotransfer in signal transduction pathways.

157 the mechanisms of molecular recognition and phosphotransfer in these systems.

158 okaryotic sensor kinases that are central to phosphotransfer in two-component signal transduction sys

159 ed failing heart, adenylate kinase-catalyzed phosphotransfer increased by 134% and contributed 21% to

160 For CheA-->CheY phosphotransfer, increasing ionic strength resulted in i

161 Phosphotransfer induces further ordering of the loop reg

162 partner to produce the ideal environment for phosphotransfer is addressed in this review in the light

163 ineer autoinhibition into the kinase so that phosphotransfer is possible only upon binding to the sca

164 phosphoryl group to Nla28 in vitro, that the phosphotransfer is specific, and that a substitution in

165 -type CheY, allowing us to explore CheA-CheY phosphotransfer kinetics and binding kinetics without in

166 binding one side of a dimerization/histidine phosphotransfer-like (DHpL) domain.

167 he helices in the dimerization and histidine phosphotransfer-like domain, where the phosphoacceptor h

168 kinase activity, indicating that Stk uses a phosphotransfer mechanism similar to the mechanism used

169 rmation from the two systems is relayed by a phosphotransfer mechanism to a shared integrator protein

170 e and the transduction of this signal, via a phosphotransfer mechanism, to the response regulator Chr

171 and this signal is transduced by a conserved phosphotransfer mechanism.

172 Alternative phosphotransfer mechanisms were explored; adenylate kina

173 re comprised of a single histidine-aspartate phosphotransfer module, are the dominant signaling pathw

174 Rather, the integrated phosphotransfer network was required for delivery of hig

175 e K(ATP) channel complex, anchoring cellular phosphotransfer networks and facilitating delivery of mi

176 Thus, the plasticity of phosphotransfer networks contributes to the effective fu

177 nucleotide- and glycolytic enzyme-catalysed phosphotransfer networks in supporting the adaptivity an

178 ion protein resulted in a 3-fold increase in phosphotransfer over that of the dark state.

179 ne kinases (KinA, KinB, KinC, and KinD) by a phosphotransfer pathway composed of Spo0F and Spo0B.

180 PhoP is activated in turn through a classic phosphotransfer pathway that is typical in such systems.

181 Histidine-aspartic acid phosphotransfer pathways are central components of proka

182 This suggests the existence of alternative phosphotransfer pathways in the myocardium, the identity

183 a new tool to study histidine-aspartic acid phosphotransfer pathways.

184 ntal standard free energies of hydrolysis (a phosphotransfer potential benchmark) is correlated with

185 phate bonding and connection to experimental phosphotransfer potential is presented.

186 iophospho-group in these proteins has a high phosphotransfer potential, similar to that of the phosph

187 aration: inclusion of the load driver's fast phosphotransfer processes restores the capability of a s

188 Phosphotransfer profiling was used to map the connectivi

189 ng a systematic biochemical technique called phosphotransfer profiling we have identified a multicomp

190 sponse regulator, and a new technique called phosphotransfer profiling, in which a purified histidine

191 n signalling inhibitor ARABIDOPSIS HISTIDINE PHOSPHOTRANSFER PROTEIN 6 (AHP6), is involved in regulat

192 The phosphotransfer protein IIA(Glc) of the bacterial phosph

193 stems channel information into the histidine phosphotransfer protein, LuxU, and/or the response regul

194 domain in the same protein; from there to a phosphotransfer protein, RcsD; and from there to RcsB.

195 Our results suggest that the histidine phosphotransfer protein, RdeA, and the response regulato

196 The histidine-containing phosphotransfer protein-B (HptB; PA3345) is an intermedi

197 xin signaling triggers ARABIDOPSIS HISTIDINE PHOSPHOTRANSFER PROTEIN6 (AHP6), which then represses cy

198 Arabidopsis thaliana histidine phosphotransfer proteins (AHPs) are similar to bacterial

199 ansferred to cytosolic Arabidopsis histidine phosphotransfer proteins (AHPs), which have been suggest

200 are similar to bacterial and yeast histidine phosphotransfer proteins (HPts), which act in multistep

201 In contrast, the histidine-containing phosphotransfer proteins (OsHPs) and response regulators

202 ed by a multistep phosphorelay system of His phosphotransfer proteins and different classes of respon

203 hway, including histidine kinases, histidine phosphotransfer proteins and response regulators.

204 His phosphotransfer proteins of Charophyceae seemed to be mo

205 ves hybrid histidine protein kinase sensors, phosphotransfer proteins, and regulators as transcriptio

206 nsor histidine kinases, histidine-containing phosphotransfer proteins, and response regulators (ARRs)

207 stems, involving His kinases, His-containing phosphotransfer proteins, and response regulators, have

208 ases and the downstream histidine-containing phosphotransfer proteins, but is independent of the ARRs

209 on of 54 His protein kinases, His-containing phosphotransfer proteins, response regulators, and relat

210 gulators, and sometimes histidine-containing phosphotransfer proteins.

211 Here we report that the phosphotransfer rate increases approximately 25-fold whe

212 ocardium, the net adenylate kinase-catalyzed phosphotransfer rate was 10% of the total ATP turnover r

213 Here, we report the phosphotransfer rates between two genetically constructe

214 CheA also makes significant contributions to phosphotransfer rates in chemotactic signaling.

215 and combined effects of NaCl and glycerol on phosphotransfer rates within the SLN1-YPD1-SSK1 phosphor

216 sensory systems that are built around a core phosphotransfer reaction between histidine kinases and t

217 le autokinase reaction and/or the reversible phosphotransfer reaction between PhoR approximately P an

218 ars to be a transition state analogue in the phosphotransfer reaction between the proteins.

219 ng site for CheY, which might facilitate the phosphotransfer reaction by tethering CheY in close prox

220 The importance and mechanism of this phosphotransfer reaction for energy-consuming processes

221 thymidylate kinase (TMPK) that catalyzes the phosphotransfer reaction for formation of dTDP from dTMP

222 While the autokinase reaction, the forward phosphotransfer reaction from PhoR approximately P to Ph

223 the contribution of P2 to the CheA --> CheY phosphotransfer reaction in the Escherichia coli chemota

224 lows an in-line, predominantly dissociative, phosphotransfer reaction mechanism, and that closure of

225 combined effects of glycerol and NaCl on the phosphotransfer reaction rates are different from the in

226 The phosphotransfer reaction was halted with a MisR/D52A mut

227 In addition to the canonical kinase phosphotransfer reaction, the conversion requires cleava

228 5 are appropriately stationed for an in-line phosphotransfer reaction.

229 d it may lower the activation barrier of the phosphotransfer reaction.

230 ansition state analogue in a protein-protein phosphotransfer reaction.

231 phosphorylation (aspartate 53) abolishes the phosphotransfer reaction.

232 econd order rate constants that describe the phosphotransfer reactions (phospho-IIA(Glc) to IICB(Glc)

233 Whereas the two-component autokinase and phosphotransfer reactions are well-understood, the mecha

234 e rate constants for the forward and reverse phosphotransfer reactions between IIA(Glc) and IICB(Glc)

235 meters capturing the cognate and non-cognate phosphotransfer reactions between the systems.

236 Phosphotransfer reactions between YPD1 and SLN1-R1 or SK

237 , MprA and MprB were shown to participate in phosphotransfer reactions characteristic of two-componen

238 Phosphotransfer reactions integrate ATP-consuming with A

239 The in vivo order of phosphotransfer reactions is believed to proceed from SL

240 mical methodology needed to adequately model phosphotransfer reactions with a reasonable description

241 hosphoaspartate serves as an intermediate in phosphotransfer reactions, and in P-type ATPases, also m

242 To promote rapid phosphotransfer reactions, CheA contains a phosphoaccept

243 ate the second-order rate constants for both phosphotransfer reactions.

244 In vitro analysis of phosphotransfer relationships revealed that LuxU can spe

245 es that constitute this signaling pathway: a phosphotransfer relay, an EIN2-based unit, a ubiquitin-m

246 drial oxidative phosphorylation coupled with phosphotransfer relays provides an efficient energetic u

247 that was dependent on HahK and its putative phosphotransfer residues.

248 th the wild type, had a blunted AK-catalyzed phosphotransfer response, lowered intracellular ATP leve

249 center, sheds light on the evolution of TCS phosphotransfer reversibility.

250 n this motif, a single histidine kinase (HK) phosphotransfers reversibly to two separate output respo

251 on systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved componen

252 In Glc uptake, the phosphotransfer sequence is: phosphoenolpyruvate --> Enz

253 The first two reactions in the phosphotransfer sequence of bacterial phosphoenolpyruvat

254 Enzyme I (EI) is the first protein in the phosphotransfer sequence of the bacterial phosphoenolpyr

255 zyme IICB(Glc), the last two proteins in the phosphotransfer sequence of the phosphoenolpyruvate:gluc

256 t mitochondrial switch with dual function in phosphotransfer serving local GTP supply and cardiolipin

257 I (EI), the first component of the bacterial phosphotransfer signal transduction system, undergoes on

258 pt that its putative histidine and threonine phosphotransfer sites have been replaced with glutamine.

259 Without high phosphotransfer specificity between cognate HKs and RRs,

260 brid kinases exhibit a dramatic reduction in phosphotransfer specificity in vitro relative to canonic

261 Here we report that the in vitro phosphotransfer specificity is relaxed in hybrid two-com

262 In contrast, phosphotransfer specificity is retained in classical two

263 airs coevolve unique interfaces that dictate phosphotransfer specificity.

264 o-phosphorylation of CqsS whereas subsequent phosphotransfer steps and CqsS phosphatase activity are

265 r energy state, yet the contribution of this phosphotransfer system in coupling myocardial metabolism

266 otic "two-component" histidine-aspartic acid phosphotransfer system, enabling a comparison of the tra

267 , in the compartmentalized cell environment, phosphotransfer systems shunt diffusional barriers and s

268 e find that single stage phosphorylation and phosphotransfer systems that transmit signals from a kin

269 By contrast, phosphotransfer systems, and single and double phosphory

270 film formation is hindered in the absence of phosphotransfer through the PTS(Ntr), but only in the pr

271 ETR1 histidine kinase activity and phosphotransfer through the receiver domain are not requ

272 AK1 phosphotransfer thus transduces stress signals into adeq

273 te (ATP) and orients the gamma phosphate for phosphotransfer to a reactive histidine on the phosphoac

274 an stimulate autophosphorylation followed by phosphotransfer to a response regulator (RR) in the two-

275 orylation of a DosS His residue, followed by phosphotransfer to an Asp residue of the response regula

276 or control normally but had reduced rates of phosphotransfer to CheB and CheY.

277 ped-flow fluorescence experiments to monitor phosphotransfer to CheY from phosphorylated wild-type Ch

278 revealed that LuxU can specifically reverse phosphotransfer to CqsS, LuxQ, and VpsS.

279 Glc N terminus caused a 20-fold reduction in phosphotransfer to membrane-bound IICBGlc from Salmonell

280 e contribution of adenylate kinase-catalyzed phosphotransfer to myocardial energetics.

281 the cytoplasmic NarX autokinase activity and phosphotransfer to NarL, the cognate response regulator.

282 try with Asp1144 from the SLN1-R1 domain for phosphotransfer to occur.

283 servative mutation E67Q dramatically reduces phosphotransfer to P1 without significantly affecting th

284 n multiple rounds of autophosphorylation and phosphotransfer to PhoP, which, in turn, drives the expr

285 hat prokaryotes and eukaryotes alike utilize phosphotransfer to regulate cellular functions.

286 d (160 s(-)(1)) and is strongly favored over phosphotransfer to SKN7-R3.

287 8Q-YPD1 mutant was significantly affected in phosphotransfer to SSK1-R2 ( approximately 680-fold decr

288 We used in vitro analysis of phosphotransfer to start to determine why R.sphaeroides

289 HmpE, was capable of autophosphorylation and phosphotransfer to the CheY homologue HmpB.

290 the wavelength-dependence of photostimulated phosphotransfer to the E. coli flagellar motor response

291 toluene exposure initiated an intramolecular phosphotransfer to the response regulator domain that re

292 Because the rate constants for phosphotransfer to/from HPr were largely unaffected, we

293 nd the phosphorylated His-189 is in-line for phosphotransfer to/from the ligand.

294 ted signaling reactions: autophoshorylation, phosphotransfer (to a partner Response Regulator (RR) pr

295 Up-regulation of creatine kinase phosphotransfer, to mimic metabolic conditions of adult

296 Rate comparisons of D314N Csk-promoted phosphotransfer using a series of fluorotyrosine-contain

297 Selective phosphotransfer was observed from CheA(3)-P to the respo

298 Although phosphotransfer was slower with CheADeltaP2 (k(cat)/K(m)

299 ing affinity as well as the rate of chemical phosphotransfer, whereas Lys+2 and Lys+3 both serve to e

300 ve conformation that binds ATP and catalyzes phosphotransfer without Mg2+.