ライフサイエンスコーパス: photoactivation

1 diffusion of PpSB1-LOV is not influenced by photoactivation.

2 or the monochromatic UV light enabling rapid photoactivation.

3 tein binding sites utilizing benign, near-UV photoactivation.

4 ns with other membrane proteins upon in-cell photoactivation.

5 to phycobilisomes, but is not essential for photoactivation.

6 formational rearrangements that occur during photoactivation.

7 nd global structural changes in the OCP upon photoactivation.

8 ecular brightness of TagRFP-T and negligible photoactivation.

9 tudy molecules exhibiting photobleaching and photoactivation.

10 A domain from an inhibited conformation upon photoactivation.

11 uronal GABAA receptors following ultraviolet photoactivation.

12 proteins enables directed HNE delivery upon photoactivation.

13 romyography with hypercapnia and optogenetic photoactivation.

14 ve conjugates against cancer cell lines upon photoactivation.

15 lical content did not change measurably upon photoactivation.

16 fluorescence emission spectra that accompany photoactivation.

17 ha factor into the ligand-binding site after photoactivation.

18 tosystem II (PSII) reaction center is termed photoactivation.

19 strom labeling radius for the diazirine upon photoactivation.

20 e ion mobility mass spectrometry adapted for photoactivation.

21 time of postsynaptic GABAergic currents upon photoactivation.

22 en these neurons and T4 cells using neuronal photoactivation.

23 lysate and showed robust labeling only upon photoactivation.

24 ection of undissociated precursor ions after photoactivation.

25 ulatory domain that senses light and induces photoactivation.

26 sed to measure methacrylate conversion after photoactivation (700 mW/cm(2) x 60s) and after 72 h.

27 Upon UVA photoactivation, 8-methoxypsoralen alkylates both strand

28 with Ca(2+) stabilizes the intermediates of photoactivation, a feature especially evident at long in

29 Upon photoactivation, a fraction of Rh1 is internalized and d

30 Labeled worms showed very bright signal upon photoactivation after hatching, which allowed us to exam

31 monitoring activity; Channelrhodopsin-2 for photoactivation; allatostatin receptor for inactivation

32 the same isoforms of recoverin and GRK1, and photoactivation also triggers a calcium decline in cones

33 ered to colitic WT mice immediately prior to photoactivation, also afforded protection against thromb

34 Photoactivation and biochemical approaches show that lys

35 pigment epithelial lipofuscin, subsequent to photoactivation and cleavage, serve to activate compleme

36 distorted conformation of the retinal after photoactivation and decelerates energy transfer into the

37 sed on the role of the OCP N-terminal arm in photoactivation and excitation energy dissipation.

38 We used photoactivation and fluorescence recovery after photoble

39 hese elements influence the dynamic range of photoactivation and how activation can be improved to li

40 Here, we used T-cell receptor (TCR) photoactivation and imaging methodology to demonstrate t

41 the nucleus, we have demonstrated that both photoactivation and nuclear localization of UVR8 are req

42 m illumination and was verified by quantized photoactivation and photobleaching.

43 ve compared the use of DRONPA and Dendra2 in photoactivation and photoconversion experiments.

44 Photoactivation and photodissociation have long proven t

45 lity (SA) changes at key OCP residues during photoactivation and relaxation.

46 t side-chain dynamics play a crucial role in photoactivation and signaling of PpSB1-LOV via modulatio

47 Photoactivation and thermal decay of rhodopsin proceed s

48 The photoactivation and visualization are nearly simultaneou

49 large Stokes shifts, (ii) photoconversions, photoactivation, and photoswitching, (iii) phototoxicity

50 enerated using laser-coupled rose Bengal dye photoactivation, and the infarct localized using tetrazo

51 This process, known as photoactivation, appeared to support the LO model since

52 , we used a refined fluorescence decay after photoactivation approach and single-molecule tracking.

53 tions that will facilitate extension of this photoactivation approach to other proteins.

54 However, photoactivation approximately 1 min after the induction

55 e fluorescent probes were obtained with fast photoactivation ( approximately 1 min) and high fluoresc

56 singly, two effects of locus coeruleus TH(+) photoactivation are sensitive to hippocampal D1/D5 recep

57 the extent of small molecules released after photoactivation as well as pinpoint the location at whic

58 Under photoactivation at 365 nm, they are even more powerful a

59 Photoactivation at F579AzF, a residue behind the selecti

60 This avoids photoactivation at low irradiance.

61 gnal transmission mechanisms involved in its photoactivation brought about through a cis-trans photoi

62 dehydrocoupling catalyst and not to require photoactivation, but otherwise operated via a two-step m

63 ing complete domain dissociation, occur upon photoactivation, but with alteration of secondary struct

64 b, Photoactivation by blue light enhanced voltage signals e

65 Upon photoactivation by blue-green light, OCP binds to the ph

66 in photoprotection, the precise mechanism of photoactivation by this protein is not well-understood.

67 of the PRG can also be brought about without photoactivation, by raising the pH of the enzyme (pKa of

68 namic remodeling of adherens junctions using photoactivation, calcium switch, and coimmunoprecipitati

69 The fact that green-light triggered photoactivation can be efficiently performed both with t

70 s induced by iridium photosensitizers during photoactivation can increase the levels of enzymes invol

71 The photoactivation capability of our CRISPR-plus method is

72 model that describes the first steps of the photoactivation cascade in spatiotemporal detail and sin

73 ted rats breathing room air, bilateral ArchT photoactivation caused a very small BP reduction that wa

74 Photoactivation causes oxidative damage to specific hist

75 pH stability, faster photoactivation, higher photoactivation contrast and better photostability.

76 In vivo, CL photoactivation could be shown by using the tumor-specif

77 ith <10 nm localization precision, while the photoactivation/deactivation mode offers slower imaging,

78 bers lack GABA, the aversion evoked by their photoactivation depended on glutamate- and GABA-receptor

79 em with a new imaging approach called PhADE (PhotoActivation, Diffusion and Excitation).

80 to identify movements of other helices upon photoactivation, double electron-electron resonance (DEE

81 Using concurrent IR photoactivation during electron transfer dissociation (E

82 of its modular design and tunability of the photoactivation efficiency and photophysical properties,

83 ng nanoparticles are described that, upon UV photoactivation, enable controlled acidification of impa

84 tome in vivo analysis (TIVA) tag, which upon photoactivation enables mRNA capture from single cells i

85 a quantitative relation between a pigment's photoactivation energy and its peak-absorption wavelengt

86 l, which is much larger than the 60-kcal/mol photoactivation energy at 500 nm.

87 Photoactivation evoked a rapid depolarization, increased

88 ved the quantum yield and sensitivity of the photoactivation experiment by employing PSII microcrysta

89 Fluorescence photobleaching and photoactivation experiments also revealed that 1) althou

90 ency of the hollow-core fiber for conducting photoactivation experiments and perform various intact p

91 Photoactivation experiments demonstrated that diffusion

92 Photoactivation experiments indicate that microvillar ac

93 Real-time dynamics and photoactivation experiments of hTR in Cajal bodies (CBs)

94 spectrometer for robust, efficient, and safe photoactivation experiments.

95 ilitates single agent-mediated deeper tissue photoactivation, extended imaging and theranostic multim

96 Fluorescence decay after photoactivation (FDAP) and fluorescence recovery after p

97 tial measurements of fluorescent decay after photoactivation (FDAP) of Dronpa-labeled actin.

98 Using a novel in vitro photoactivation fluorescence assay, the EBP50-ezrin inte

99 itution reduced the excitation light-induced photoactivation from the dark to fluorescent state.

100 ger states, especially those evoked via AgRP photoactivation, fundamentally altered sequences of beha

101 ster maturation, better pH stability, faster photoactivation, higher photoactivation contrast and bet

102 ferred tag for two-color diffraction-limited photoactivation imaging and for super-resolution techniq

103 Photoactivation in PRSX8-ArchT rats reduced breathing fr

104 w that individual cells encode the timing of photoactivation in relation to the sniff in both the tim

105 site-specific anxiolytic effects on in situ photoactivation in the brain.

106 ciently generate radical PE lipids following photoactivation in the gas phase.

107 In contrast, PV photoactivation indirectly induced theta-band-limited, e

108 ements confirmed that in the nanodiscs, SRII photoactivation induces helix movement in the HtrII memb

109 theory, the prevalence of two mechanisms of photoactivation (internal photoemission versus interband

110 This photoactivation involves a unique series of structural c

111 pectroscopic analysis suggests that PATagRFP photoactivation is a two-step photochemical process invo

112 tion-state structural data, reveals that OCP photoactivation is accompanied by a 12 angstrom transloc

113 also show that the opening of the OCP during photoactivation is caused by the movement of the C-termi

114 neration of the visual pigment following its photoactivation is critical for the function of cone pho

115 relatively low overall quantum efficiency of photoactivation is explained by the requirement of corre

116 Photoactivation kinetics were assessed from the rate of

117 Their photoactivation led to cell death as measured by ion lea

118 ble-plane detection scheme with fluorescence photoactivation localization microscopy (FPALM) enabling

119 Fluorescence photoactivation localization microscopy (FPALM) images b

120 obtained using superresolution fluorescence photoactivation localization microscopy (FPALM) in nonpo

121 Using quantitative high-speed fluorescence photoactivation localization microscopy (FPALM), we prob

122 oteins in mammalian cells using fluorescence photoactivation localization microscopy (FPALM).

123 luorescence (TIRF) microscopy, and live-cell photoactivation localization microscopy (PALM) demonstra

124 Photoactivation localization microscopy (PALM) is used t

125 tion microscopy methods such as fluorescence photoactivation localization microscopy and photoactivat

126 New work using high-speed fluorescence photoactivation localization microscopy now reveals the

127 This study uses single-particle tracking and photoactivation localization microscopy to analyze cell-

128 Here, we applied dual color photoactivation localization microscopy using photoactiv

129 (3D), super-resolution biplane fluorescence photoactivation localization microscopy with Eos-conjuga

130 ly formed spines, using a technique based on photoactivation localization microscopy.

131 Here, we used photoactivation, localization, and tracking in live Esch

132 The effective photoactivation makes thio-caged fluorophores promising

133 volved in the initial steps of the rhodopsin photoactivation mechanism and their optical spectra.

134 plored the role of this residue, Y21, in the photoactivation mechanism of the BLUF protein AppABLUF b

135 n of a stable light state, consistent with a photoactivation mechanism that involves proton transfer

136 n adenine dinucleotide (FAD) and an internal photoactivation mechanism.

137 PAmCherry1 mutants, we propose the detailed photoactivation mechanism.

138 which is vital to determining the rhodopsin photoactivation mechanism.

139 ble progress has been made in uncovering the photoactivation mechanisms of both LOV and BLUF domains.

140 n design and a deeper understanding of their photoactivation mechanisms will allow the development of

141 These particles have been tested for photoactivation-mediated cytotoxicity using near-visible

142 , including conventional diffraction-limited photoactivation microscopy, super-resolution photoactiva

143 intercellular flux of small molecules using photoactivation microscopy.

144 To broaden photoactivation modalities, here we report a new strateg

145 nt of the field, including the design of new photoactivation modalities, the continuous expansion of

146 Photoactivation occurs within a range of skin type model

147 ase changes to the cone outer segment, where photoactivation occurs.

148 Photoactivation of "snap-top" stoppers over the pore ope

149 ely occurs via a free-radical mechanism upon photoactivation of 1.

150 UVA photoactivation of 6-TG, ciprofloxacin and ofloxacin was

151 We also achieve 2P photoactivation of a metabotropic receptor, LimGluR3, wi

152 teria, the trigger for this mechanism is the photoactivation of a soluble carotenoid protein, the ora

153 sphopeptide product ions due to the infrared photoactivation of AI-ETD and show that modifying phosph

154 Photoactivation of aqueous chlorine could promote degrad

155 Here, using photoactivation of BDNF or syt-IV (a regulator of exocyt

156 Photoactivation of bioactive molecules allows manipulati

157 n fact, these operating principles allow the photoactivation of BODIPY fluorescence with large bright

158 phototoxicity and emit UV light locally, for photoactivation of caged compounds and, in particular, u

159 in a microfluidic device and illuminated for photoactivation of channelrhodopsin-2 to induce contract

160 ning photostimulation glutamate uncaging and photoactivation of channelrhodopsin-2 were used to probe

161 assemblies is based on the enantio-selective photoactivation of chiral NPs and clusters, followed by

162 We found that photoactivation of ChR2 in genetically defined populatio

163 VTA photoactivation of ChR2-expressing mice reinforced instr

164 It is established that blue-light (BL) photoactivation of CRY is sufficient to depolarize and a

165 CL photoactivation of Cy7 azide in vitro showed significant

166 Furthermore, photoactivation of DAG itself was sufficient to induce t

167 nelrhodopsin ChRmine to achieve transcranial photoactivation of defined neural circuits, including mi

168 Here, we demonstrate that UVA photoactivation of DNA S(4)TdR does not generate reactiv

169 a CL dose-dependent manner in vitro using CL photoactivation of DOX azide.

170 In the presence of diaminobenzidine (DAB), photoactivation of dye-filled vesicles yields an osmioph

171 ese metrics on units that were suppressed by photoactivation of either SOM(+) or PV(+) neurons.

172 turation, and antitumor immunity through the photoactivation of engineered chemokine receptors and ca

173 Direct photoactivation of excitatory neurons, which did not cha

174 tion of radical pairs of electrons requiring photoactivation of flavin adenine dinucleotide (FAD) bou

175 Profound transient photoactivation of G(i/o) signaling by (b)isoRho led to

176 c adenosine monophosphate, whereas transient photoactivation of G(q) signaling by (h)Mo enhanced worm

177 racellular antibodies, and demonstrated that photoactivation of gelsolin and beta2-adrenergic recepto

178 2PE-compatible photoswitches (section 1) for photoactivation of genetically modified glutamate recept

179 Local photoactivation of genetically targeted LiGluR, ChR2, or

180 Comparison of sequence coverages upon UV photoactivation of HA and of the HA.antibody complex ind

181 at were biotinylated following rebinding and photoactivation of labeled GAPDH, aldolase, lactate dehy

182 feasibility of achieving cell-type-specific photoactivation of macaque neocortical neurons.

183 Here we report that nAcc photoactivation of mesoaccumbens glutamatergic fibers pr

184 We report the in vivo photoactivation of meta-azipropofol, a potent analog of

185 We successfully applied the strategy to the photoactivation of mifepristone (RU-486), an antiprogest

186 After photoactivation of mKikGR near the surface, rapid diffus

187 -depolarizing optogenetic tools for targeted photoactivation of neuron firing.

188 ity for imaging thick specimens or selective photoactivation of neuronal networks.

189 Photoactivation of nonfluorescent NQMP-caged 3-allyloxyf

190 Finally, we show how photoactivation of opto-beta2AR in vivo modulates neuron

191 We demonstrate that photoactivation of PA-GFP is the result of a UV-induced

192 Furthermore, the photoactivation of paAIP2 expressed in amygdalar neurons

193 The photoactivation of paAIP2 in neurons for 1-2 min during

194 Photoactivation of paNPs in fatty acid-treated INS1 cell

195 Photoactivation of parvalbumin-positive interneurons (PV

196 We further show specific photoactivation of parvalbumin-positive interneurons in

197 Here we show that the photoactivation of phytochromes triggers the expression

198 We found that photoactivation of PPTg glutamate cell bodies could serv

199 i1 diffusion using single-particle tracking, photoactivation of protein ensembles, and Monte Carlo si

200 ns, nor did it prevent protrusion induced by photoactivation of Rac.

201 es within a microfluidic device, subcellular photoactivation of Rac1, diffusion of cytoplasmic rheolo

202 When a new lamellipodium was triggered with photoactivation of Rac1, the nucleus moved toward the ne

203 rent model for the formation of A2E requires photoactivation of rhodopsin and subsequent release of a

204 The translocation of Grb14 requires photoactivation of rhodopsin, but not signaling through

205 Upon photoactivation of rhodopsin, the heterotrimeric G prote

206 mammalian cells and neurons by visible-light photoactivation of signaling molecules.

207 nstrate this approach in vivo in mice, where photoactivation of SNAP-mGluR2 in the medial prefrontal

208 Photoactivation of tetrazoles to form nitrile imines pri

209 oxygen and nitrogen species are generated by photoactivation of the anticancer platinum(IV) complex t

210 This transformation allowed the heterolytic photoactivation of the Ar-Cl bond in protic media and th

211 of this catalyst are ascribed to the in situ photoactivation of the BDDL surface during the photoelec

212 ically respond to hypercapnia or optogenetic photoactivation of the C4 cervical cord.

213 of charge reduced precursor ions or infrared photoactivation of the entire ion population concomitant

214 of the charge reduced precursors or infrared photoactivation of the entire ion population during the

215 tical electrophysiology, although blue light photoactivation of the FlicR1 chromophore presents a cha

216 This mechanism is induced by photoactivation of the Orange Carotenoid Protein (OCP).

217 dynamics of the crucial W104 residue during photoactivation of the protein.

218 Thus, photoactivation of the recently developed neutral organi

219 without affecting novelty responses, whereas photoactivation of the same neurons reduces exploration

220 By single-cell photoactivation of the T cell antigen receptor (TCR), we

221 By single-cell photoactivation of the T cell antigen receptor, we show

222 Highly efficient photoactivation of the taxoid-tetrazoles inside the mamm

223 s recent advancements in the use of UCNs for photoactivation of therapeutic agents.

224 albumin GABAergic interneurons and that nAcc photoactivation of these fibers drove AMPA-mediated cell

225 Photoactivation of these long-lived, reactive states is

226 ooming-evoked defensive flight behavior, and photoactivation of these neurons resulted in defense-lik

227 Photoactivation of these neurons reversed social avoidan

228 In addition, our results indicate that photoactivation of these projections modulates other beh

229 However, photoactivation of these terminals did not induce self-s

230 In sucrose operant conditioning, the photoactivation of these terminals increased nose-poking

231 Here, we exploit the selectivity of photoactivation of thiocarbonylthio compounds to impleme

232 Photoactivation of titanium dioxide nanoparticles (TiO2N

233 Sustained photoactivation of VALopA not only suppresses spontaneou

234 arried out by a signaling pathway that links photoactivation of visual pigments in retinal photorecep

235 Vision relies on photoactivation of visual pigments in rod and cone photo

236 We found that photoactivation of VTA glutamatergic neurons produced ro

237 Photoactivation of VTA slices from ChR2-expressing mice

238 Here, we test whether local photoactivation of VTA VGluT2 neurons expressing Channel

239 signaling properties of opsin, stemming from photoactivation or arrestin binding.

240 Super-resolution fluorescence imaging by photoactivation or photoswitching of single fluorophores

241 switchable tethered ligands (PTLs) to enable photoactivation, or photoantagonism, while preserving no

242 Supplemental infrared photoactivation outperforms collisional activation for m

243 After photoactivation, PAiRFPs slowly revert back to initial s

244 rsor ions remains undissociated after the UV photoactivation period in order to prevent overdissociat

245 response across tone frequencies, whereas PV photoactivation preserved normal specificity of learning

246 We observed a biphasic photoactivation process in which carotenoid migration pr

247 ArchT photoactivation produced similar BP changes in CaMKII-Ar

248 terial and following a clinically acceptable photoactivation protocol.

249 test this hypothesis, we used a fluorescence photoactivation pulse-escape technique to compare the ki

250 the pausing behavior, we used a fluorescence photoactivation pulse-escape technique to measure the ra

251 t for quantitative spectroscopic analysis or photoactivation purposes.

252 ze the active conformation of rhodopsin upon photoactivation (R*).

253 ion of cryptochrome supposedly arises from a photoactivation reaction involving radical pair formatio

254 ative imaging using fluorescence decay after photoactivation recordings of photoactivatable GFP-tagge

255 Under anesthesia, ArchT photoactivation reduced sympathetic nerve activity and B

256 ert back to initial state, enabling multiple photoactivation-relaxation cycles.

257 ermined, the molecular mechanisms underlying photoactivation remain elusive.

258 Photoactivation results in a slightly larger resilience

259 We propose a photoactivation scheme that maximally separates the acti

260 Photoactivation significantly modifies the flexibility a

261 cells using cell fusion, photobleaching, and photoactivation strategies in combination with conventio

262 on proteins and then used photoconversion or photoactivation strategies to create distinct population

263 urther expand the established utility of the photoactivation strategy in biological applications by o

264 Photoactivation studies demonstrated irreversible adduct

265 Photoactivation studies suggest that the soluble pool of

266 ed proteins change little or not at all upon photoactivation, suggesting that rigid-body motions of h

267 e recovery after photobleaching, uncaging or photoactivation/switching as well as single-particle tra

268 We used the pulse-escape fluorescence photoactivation technique to analyze neurofilament trans

269 the MeRho-Az scaffold is less susceptible to photoactivation than other commonly used azide-based sys

270 ocleavage experiments demonstrate that, upon photoactivation, the conjugate cleaves the DNA backbone

271 After photoactivation, the fluorophore is bright and photostab

272 On photoactivation, the OCP converts from a stable orange f

273 Upon photoactivation, the re-exposed hydroxy group on D-F07 t

274 Upon photoactivation, the second messenger of phototransducti

275 Upon photoactivation, these probes can provide 10(4)-10(6) ph

276 ability of synaptically evoked spiking after photoactivation; this did not occur with a proton pump.

277 In-depth photoactivation through tissue phantoms and in vivo acti

278 s, are photoreceptors requiring simultaneous photoactivation to interact, enabling high spatiotempora

279 ser-scanning microscopy and two-photon laser photoactivation to measure their rate of turnover in ind

280 ssociation (AI-ETD) uses concurrent infrared photoactivation to promote product ion generation and ha

281 stimulation parameters determined to confine photoactivation to targeted neurons, simultaneous excita

282 PhotoGate bypasses the requirement of photoactivation to track single particles at surface den

283 ell-permeable ubiquitin probe that undergoes photoactivation upon 365 nm UV treatment and enables int

284 wide dynamic range, low background, and fast photoactivation using a low-intensity light while render

285 with near diffraction-limited confinement of photoactivation using two-photon illumination and 3D loc

286 -assembly of the Mn(4)CaO(5) cluster, termed photoactivation, utilizes the same highly oxidizing spec

287 blue exclusion) was observed at 20 muM, and photoactivation was demonstrated in HeLa cells using red

288 Photoactivation was tuned by adjusting the length of the

289 Using in situ photoactivation, we demonstrated that B cells migrate fr

290 Furthermore, for fast, multi-region photoactivation, we describe the use of 2P-digital holog

291 To define the structural basis of PAmCherry1 photoactivation, we determined its crystal structure in

292 further insights into structural details of photoactivation, we investigated the full-length Agp1 ba

293 Using photoactivation, we measured the movement of PA-GFP-TPX2

294 ge conformational changes in rhodopsin after photoactivation, we propose that ordered waters contribu

295 r thickness upon rhodopsin incorporation and photoactivation were mostly absent.

296 ations, neither opsin-arrestin complexes nor photoactivation were necessary for cell loss.

297 heir all-trans-retinal chromophore following photoactivation, which necessitates the existence of pat

298 To facilitate deep-tissue photoactivation with near-infrared light, we measured th

299 After photoactivation with spatially restricted light, SPOT2.1

300 tes through state-selective (E and Z isomer) photoactivation with visible light.