ライフサイエンスコーパス: phytoestrogen

1 , we examined whether resveratrol might be a phytoestrogen.

2 ctones, which are mycotoxins and not natural phytoestrogen.

3 rcuma comosa Roxb., has been identified as a phytoestrogen.

4 contained lower amounts of naturally present phytoestrogens.

5 wn to be a suitable method for hydrolysis of phytoestrogens.

6 gency-sponsored quality assurance scheme for phytoestrogens.

7 in engineering plants to contain isoflavone phytoestrogens.

8 tofu), soy protein, or urinary excretion of phytoestrogens.

9 bone density may be favorably influenced by phytoestrogens.

10 s, including the naturally occurring dietary phytoestrogens.

11 e of the biological effects of diets rich in phytoestrogens.

12 ense properties, as well as similar roles as phytoestrogens.

13 f the biological and medicinal properties of phytoestrogens.

14 , was investigated for 29 mycotoxins and two phytoestrogens.

15 ibitors belonging to the coumestan family of phytoestrogens.

16 phytoestrogens or on a chow nearly devoid of phytoestrogens.

17 s under the stimulation of estrogens but not phytoestrogens.

18 ning diet [(P-600); that had 600 microg/g of phytoestrogens].

19 diets containing plant-derived isoflavones (phytoestrogens) afford protection against CVDs, suppleme

20 h, menopause, and climacteric, combined with phytoestrogens, alternative medicine, herbal medicine, t

21 t comprehensive suite of natural hormone and phytoestrogen analytes examined to date across a livesto

22 Resveratrol, a well-established phytoestrogen and chemopreventive agent, has gained much

23 We conclude that resveratrol is a phytoestrogen and that it exhibits variable degrees of e

24 T1A10 is important for detoxifying estrogens/phytoestrogens and aromatic acids with complementary act

25 Research on the relation between phytoestrogens and breast cancer risk has been limited i

26 Phytoestrogens and environmental xenoestrogens will fall

27 However, both phytoestrogens and estrogen inhibited RANKL-induced Ikap

28 attenuation of natural steroid hormones and phytoestrogens and estrogenic activity were assessed acr

29 Phytoestrogens and mycoestrogens, which are produced by

30 s due to their biological activity as strong phytoestrogens and potent cancer chemopreventive agents.

31 Isoflavones are classified as both phytoestrogens and selective estrogen receptor modulator

32 nd to contain lower amounts of contaminating phytoestrogens and showed increased enzyme activity for

33 ethod has been developed for the analysis of phytoestrogens and their conjugates in human urine using

34 These phytoestrogens and their metabolites have many potent ho

35 ological evidence is needed on the levels of phytoestrogens and their metabolites in foods and biolog

36 alyzed for 12 phytotoxins (5 alkaloids and 7 phytoestrogens) and 2 widely used herbicides (atrazine a

37 ne and a variety of EDCs produced by plants (phytoestrogens), and that the diversity of organic EDCs

38 Targeted analysis revealed 13 xenobiotics, phytoestrogens, and endogenous hormones in the AF extrac

39 study, the distribution of steroid hormones, phytoestrogens, and estrogenic activity was thoroughly c

40 broad class of nonsteroidal estrogens called phytoestrogens, and in the past decade there has been co

41 Phytoestrogens appear to have little effect on breast ca

42 Phytoestrogens are a group of polyphenolic plant metabol

43 hough epidemiological data are inconclusive, phytoestrogens are considered to be beneficial for a var

44 Interestingly, several dietary phytoestrogens are known to stimulate or inhibit the act

45 Phytoestrogens are non-steroidal estrogens produced from

46 Phytoestrogens are plant-derived compounds found mainly

47 Phytoestrogens are plant-produced secondary compounds th

48 nce that the pro- or anti-obesity effects of phytoestrogens are related to their relative agonist/ant

49 though natural toxins, such as mycotoxins or phytoestrogens are widely studied and were recently iden

50 veral legumes, including red clover, produce phytoestrogens as stress defense molecules, and climate

51 to that of cntnap2 mutants and show that the phytoestrogen biochanin A specifically reverses the muta

52 , these data present the first evidence that phytoestrogens can affect aggressive behavior and, concu

53 on to naturally occurring estrogens, dietary phytoestrogens can affect sexual differentiation.

54 emiological data suggest that consumption of phytoestrogens can be protective against the development

55 vironmental estrogen-like molecules, such as phytoestrogens, can also affect cardiac physiology in bo

56 that the pro- or anti-adipogenic activity of phytoestrogen chemicals is related to the ability to act

57 Phytoestrogen composition did not vary between FRG and C

58 G; free-range, FRG) and month on retail milk phytoestrogen composition was assessed for 12 consecutiv

59 correlated with concentrations of individual phytoestrogen compounds and total phytoestrogens in red

60 In red clover, exposure to eT reduced total phytoestrogen concentration by 50%, from 3.9 to 1.9 mg/g

61 Phytoestrogen concentrations in cowpea vegetative tissue

62 (eCO(2)), both alone and in combination, on phytoestrogen concentrations in red clover and cowpea.

63 Seasonal variation in milk phytoestrogen concentrations was higher for ORG than CNV

64 In urine, all of the phytoestrogen conjugates hydrolyzed within 2h under stan

65 6 proved to be detrimental to hydrolysis of phytoestrogen conjugates, especially those in plasma.

66 The authors' findings suggest that dietary phytoestrogen consumption may partially defeminize adult

67 the beneficial and/or detrimental impacts of phytoestrogen consumption through commercial rodent diet

68 have yielded conflicting outcomes, in which phytoestrogen consumption was both positively and negati

69 mals fed a phytoestrogen-free (P-free) vs. a phytoestrogen-containing diet [(P-600); that had 600 mic

70 mbined with an enzyme "blank" to correct for phytoestrogen contamination was shown to be a suitable m

71 The finding that variability in phytoestrogen content in commercial rodent diets, both w

72 or the general public, reliable data on the phytoestrogen content of food is necessary.

73 igher than the P-free values and the mbh-poa phytoestrogen content was 8-fold higher than the P-free

74 xposure duration and timing, dietary fat and phytoestrogen content, or lack of sophisticated phenotyp

75 nesis less effectively than the nonselective phytoestrogen daidzein, which effectively reproduced eff

76 initial experiments using estradiol and the phytoestrogens daidzein and genistein (compounds known t

77 Additionally, phytoestrogens decreased body weight but increased consu

78 Phytoestrogens, derived from plants possesses structural

79 on with females of both genotypes on the low phytoestrogen diet.

80 ensors and biosensors for all the classes of phytoestrogens done so far since 2019.

81 Exposure to these phytoestrogens early in life may have long-term health b

82 e cancer-preventative "mammalian" lignan or "phytoestrogen" enterolactone, formed in the gut followin

83 holesterol, fatty acids, vitamins, minerals, phytoestrogens, ethanol, and polyphenols, are either ben

84 rge range in both the amount and the type of phytoestrogens excreted.

85 idual variation seen in urinary isoflavonoid phytoestrogen excretion, we conducted a series of 3 huma

86 Early-life soy phytoestrogen exposure has been shown in Eker rats to in

87 Phytoestrogen exposure is much higher than that of ED-PP

88 support for persistent effects of early life phytoestrogen exposure on the uterus.

89 We hypothesized that phytoestrogen exposure regulates PTEN protein expression

90 he relation between uterine fibroid risk and phytoestrogen exposure.

91 tion between exposure to fungicides, dioxin, phytoestrogens, flame retardants, heavy metals and child

92 dietary xenobiotics including glycosides of phytoestrogens, flavonoids, simple phenolics and cyanoge

93 Genistein, a phytoestrogen found abundantly in soy products, is thoug

94 Resveratrol, a natural phytoestrogen found in red wine and a variety of plants,

95 ls (via Western analysis) from animals fed a phytoestrogen-free (P-free) vs. a phytoestrogen-containi

96 We used a phytoestrogen (PE) and a phytoestrogen-free (PE-Free) diet to determine whether o

97 either a phytoestrogen-rich (Phyto-600) or a phytoestrogen-free (Phyto-free) diet.

98 ales, which are nonagouti, were fed either a phytoestrogen-free control diet or one of six experiment

99 -6 weeks of age, transgenic males were fed a phytoestrogen-free diet (AIN-76A) containing 0, 100, 250

100 nts may provide the health benefits of these phytoestrogens from consumption of more widely used grai

101 wt(-1) x d(-1)), whereas the intake of these phytoestrogens from human milk is negligible (<0.01 mg/d

102 Female mice exposed neonatally to the phytoestrogen genistein (GEN) at doses similar to those

103 flammatory gene expression, because both the phytoestrogen genistein and low doses of EE were effecti

104 The phytoestrogen genistein is able to modulate uterine estr

105 with these findings, STX, tamoxifen, and the phytoestrogen genistein were able to increase SF-1 trans

106 uman TRPV6 in complex with the plant-derived phytoestrogen genistein, extracted from Styphnolobium ja

107 either methyl donors like folic acid or the phytoestrogen genistein, negated the DNA hypomethylating

108 For example, dietary intake of phytoestrogen, genistein (Gen), seems to play a preventi

109 y study has been pursued on the nonsteroidal phytoestrogen, genistein.

110 The soy isoflavone phytoestrogens, genistein and daidzein, and equol (a dai

111 enis) was associated with maternal intake of phytoestrogens, given their potential impact on estrogen

112 diet) and soy protein from which most of the phytoestrogens had been extracted (low-isoflavone diet)

113 bDiet 5001) as compared to chow with minimal phytoestrogens (Harlan 2016 Teklad) was associated with

114 Formononetin (FN), a typical phytoestrogen has attracted substantial attention as a n

115 Phytoestrogens have a similar structure to estradiol and

116 Furthermore, phytoestrogens have antineoplastic effects with inhibiti

117 ared with soy protein from which most of the phytoestrogens have been extracted, soy protein with int

118 The phytoestrogens have certain similarities to 'designer ho

119 Phytoestrogens have many beneficial medicinal properties

120 Phytoestrogens have the ability to bind estrogen recepto

121 ate intakes of soy protein containing intact phytoestrogens (high-isoflavone diet) and soy protein fr

122 ucibility and can be easily adapted to other phytoestrogens if required.

123 Genistein, a phytoestrogen implicated in reducing cardiovascular infl

124 exposure to 17beta-estradiol or genistein (a phytoestrogen in soy protein-based diets), and neonatal

125 the first generic method for the analysis of phytoestrogens in food, using automated solid-phase extr

126 s of the metabolism and disposition of these phytoestrogens in humans.

127 large body of evidence documents the role of phytoestrogens in influencing hormone-dependent states.

128 individual phytoestrogen compounds and total phytoestrogens in red clover.

129 Evidence regarding dietary phytoestrogens in relation to mortality remains limited.

130 For individual phytoestrogens in relation to total mortality, the poole

131 amental plants) increase the distribution of phytoestrogens in surface waters.

132 egume seeds and sprouts are a rich source of phytoestrogens in the form of isoflavonoids.

133 In summary, phytoestrogens, in the form of dietary isoflavones, repr

134 fants fed soy formula receive high levels of phytoestrogens, in the form of soy isoflavones, during a

135 Broadly defined, phytoestrogens include isoflavones, coumestans, and lign

136 urine, and prostatic fluid concentrations of phytoestrogens, including genistein.

137 Phytoestrogens, including isoflavones and lignans, can a

138 A higher intake of total phytoestrogens, including isoflavones, lignans, and coum

139 Primary food sources of phytoestrogens, including tofu, soy milk, whole grains,

140 have been extracted, soy protein with intact phytoestrogens increases HDL-cholesterol and apolipoprot

141 Excreta also contained phytoestrogens indicative of a soy-based diet, particula

142 The characterization of phytoestrogen intake and cancer risk has been hindered b

143 represents the first large-scale analysis of phytoestrogen intake and hypospadias.

144 sex/gender difference exists in response to phytoestrogen intake and what the possible underlying me

145 colorectal, and prostate cancers relative to phytoestrogen intake on the basis of a comprehensive dat

146 For example, the odds ratio for total phytoestrogen intake was 0.7 (95% confidence interval: 0

147 r multivariable adjustment, the higher total phytoestrogen intake was associated with lower risk of t

148 Phytoestrogen intake was not associated with breast canc

149 Phytoestrogen intake was not associated with breast canc

150 ontrols) cancers were calculated relative to phytoestrogen intake.

151 Individual phytoestrogen interventions such as dietary and suppleme

152 e P-free group, demonstrating the passage of phytoestrogens into brain.

153 terest in engineering the synthesis of these phytoestrogens into plants.

154 Phytoestrogen isoflavone intervention to engage the neur

155 Genistein is a phytoestrogen isoflavone that exerts agonist and antagon

156 From a panel of phytoestrogen isoflavones, biochanin A (BCA) was identif

157 Phytoestrogens (isoflavones and lignans) are of increasi

158 Thus, the exposure to the main PPPs and to phytoestrogens known as endocrine disruptors (EDs) is es

159 mized rats (9 weeks) on chow containing high phytoestrogen levels (Purina LabDiet 5001) as compared t

160 mice to a commercial rodent diet with higher phytoestrogen levels facilitates uterine growth in the p

161 Elevated CO(2) did not influence total phytoestrogen levels in red clover but reduced daidzein

162 plus maze and body weight were unaffected by phytoestrogen levels in the diet.

163 P-600 plasma phytoestrogen levels were 78-fold higher than the P-free

164 implantation compared with a diet with lower phytoestrogen levels.

165 significantly: (1) elevate plasma and brain phytoestrogens levels and (2) decrease brain calcium-bin

166 In the ArKO females raised on a diet high in phytoestrogens, lordosis was reduced in comparison with

167 Phytoestrogens may act as natural selective estrogen rec

168 Dietary phytoestrogens may contribute to the risk of colorectal

169 It may be logical to postulate that phytoestrogens may regulate proteins that control cellul

170 Genistein, a phytoestrogen, may have estrogenic cardioprotective acti

171 nt studies suggest that flavonoids, known as phytoestrogens, may inhibit the PD-1/PD-L1 axis.

172 humans with a soy challenge, a comparison of phytoestrogen metabolism when subjects consumed fermente

173 In addition, dietary phytoestrogens modified mammary development and tumor la

174 Here, we identify Icaritin, a phytoestrogen molecule enhances self-renewal of mouse em

175 Phytoestrogens, naturally occurring plant chemicals, hav

176 Liquiritigenin was found to be the principle phytoestrogen of the licorice extracts; however, it exhi

177 isolates and contain significant amounts of phytoestrogens of the isoflavone class.

178 This review is focused on the effects of phytoestrogens on cognition by examining clinical and an

179 needed to evaluate the long-term effects of phytoestrogens on obesity and diabetes mellitus and thei

180 The agonist/antagonist activities of phytoestrogens on PPARgamma were further assessed by qua

181 s study characterized the effects of dietary phytoestrogens on the expression of body and prostate we

182 s study characterized the effects of dietary phytoestrogens on the expression of body weight, consumm

183 er on a standard mouse chow that was rich in phytoestrogens or on a chow nearly devoid of phytoestrog

184 e interactions between tamoxifen and dietary phytoestrogens (or isoflavones) by dose and form in vivo

185 uded plasticizers, phthalates, metals, PCBs, phytoestrogens, PAHs, heterocyclic amines, antioxidants,

186 ndicate that women ingesting high amounts of phytoestrogens, particularly as isoflavones in soy produ

187 doxically, high consumption of plant-derived phytoestrogens, particularly soybean isoflavones, is ass

188 We used a phytoestrogen (PE) and a phytoestrogen-free (PE-Free) di

189 Phytoestrogen [plant estrogenic-like molecule(s)] resear

190 Evidence is emerging that dietary phytoestrogens play a beneficial role in obesity and dia

191 nd cell culture systems suggest that dietary phytoestrogens play an important role in prevention of m

192 Natural phytoestrogen polyphenols, including resveratrol (RES),

193 Phytoestrogens present in soybeans and other plant produ

194 occurring estrogen-like molecules in plants (phytoestrogens), present via soy, in animal diets can al

195 occurring estrogen-like molecules in plants (phytoestrogens), present via soy, in animal diets, exert

196 Phytoestrogens produced anxiolytic effects in both male

197 r data provide evidence that a mechanism for phytoestrogens' protective nature is partially through i

198 ng naturally occurring amounts of isoflavone phytoestrogens reduced lipid peroxidation in vivo and in

199 etection to 37 and 68 ng/L for alkaloids and phytoestrogens, respectively.

200 imental protocols, animals were fed either a phytoestrogen-rich (Phyto-600) or a phytoestrogen-free (

201 Phytoestrogen-rich soy is known to ameliorate menopause-

202 However, little is known about phytoestrogen's effects on the CNS.

203 Black cohosh and foods that contain phytoestrogens show promise for the treatment of menopau

204 and Asian populations and clinical studies, phytoestrogens show promise to improve health and brain

205 ondary aim was to evaluate the effect of soy phytoestrogen (SPE) treatment on the severity of OA.

206 metabolite equol was by far the predominant phytoestrogen species, with daidzein, genistein, formono

207 Plant-derived phytoestrogens specifically have received much attention

208 Increased intake in phytoestrogens stemmed from the search for safe alternat

209 Concomitantly, phytoestrogen stimulation resulted in decreased Akt phos

210 Soy products, which contain phytoestrogens such as genistein, are one source of expo

211 ere is a dearth of studies on its content in phytoestrogens such as isoflavones and lignans.

212 Moreover, phytoestrogens such as liquiritigenin which is common in

213 or increased consumption of other sources of phytoestrogens such as whole grains, vegetables, fruits,

214 re slightly increased in cells stimulated by phytoestrogens, suggesting that the mechanism for increa

215 trials suggests that composite and specific phytoestrogen supplementations were associated with mode

216 cts of 2 popular, commercially available soy phytoestrogen supplements on anxiety in male, diestrus f

217 D3 is a weakly acting phytoestrogen that mimics the mitogenic responses produc

218 Taken together, BCA represents a natural phytoestrogen that mitigates stroke-induced injury by in

219 The isoflavones are a group of phytoestrogens that are present in high concentrations i

220 in (FORM) is an isoflavone from the group of phytoestrogens that exhibits a broad spectrum of physiol

221 is a rich source of isoflavones--a class of phytoestrogens that has both antiestrogenic and anticarc

222 ds are rich in isoflavones, a major group of phytoestrogens that have been hypothesized to reduce the

223 cts of endogenous T-derived E2 and exogenous phytoestrogens, the authors used an aromatase knockout (

224 Despite the potential benefits of phytoestrogens, their low solubility, bioavailability, a

225 re no dietary recommendations for individual phytoestrogens, there may be great benefit in increased

226 edlings can serve multiple purposes, e.g. as phytoestrogens they can provide health benefits and as n

227 Similar to broad conversion of phytoestrogens, UGT1A10 metabolized estrogens and their

228 Because phytoestrogen use in nutritional and pharmaceutical appl

229 hindered by the absence of accurate dietary phytoestrogen values.

230 These data suggest that consumption of phytoestrogens via a soy diet for a relatively short int

231 These data suggest that consumption of phytoestrogens via a soy diet, significantly: (1) decrea

232 Use of phytoestrogens was associated with a decrease in the num

233 Previously, food analysis for phytoestrogens was performed using either HPLC-UV or GC/

234 Daidzein, another phytoestrogen, was ineffective, but equimolar concentrat

235 nformation, we hypothesized that soy-derived phytoestrogens, weak estrogen-like substances in the soy

236 Individual phytoestrogens were also significantly associated with l

237 total isoflavones, total lignans, and total phytoestrogens were associated with reduced risks; odds

238 All of these phytoestrogens were found to be photolabile under certai

239 first time, average levels of all the above phytoestrogens were measured in samples of urine collect

240 Phytoestrogens were often more abundant than steroidal e

241 logical variables measured concurrently with phytoestrogens were weakly correlated with concentration

242 improved solubility, and bioavailability of phytoestrogens which has ultimately reduced the required

243 We report an assay for phytoestrogens which is sensitive, accurate, and uses lo

244 otection products (PPPs) or they can contain phytoestrogens which may exhibit endocrine effects.

245 estrogen agonist is the plant-based group of phytoestrogens, which include isoflavones, lignans and c

246 hnology in enhancing therapeutic benefits of phytoestrogens while minimizing their potential side eff

247 ver sprouts can be considered as a source of phytoestrogens with high biological activity and as a di

248 s trace minerals and phenolic compounds, and phytoestrogens, with potential hormonal effects.