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1 with a lower limit of quantification of 0.1 picomoles.
4 profiling of digest aliquots containing low picomole amounts of carbohydrate structures either enzym
6 ctrometry (LC-ESI-MS) to detect femtomole to picomole amounts of reporter molecules results in an ult
7 ionic liquid matrices allow the detection of picomole amounts of the sodium salts of a disaccharide,
8 been possible to rapidly sequence femto- to picomole amounts of tissue-derived complex polysaccharid
11 y (R(2) > 0.9996), resolution (R(s) 1.5) and picomole detection limits, and was successfully applied
12 R(2) > 0.9996), resolution (R(s) >= 1.5) and picomole detection limits, and was successfully applied
13 This allowed better performances for the picomole detection of low mass analytes like arginine, f
16 nescent ions, accumulation of some femto- to picomoles in a neon matrix (over a time scale of tens of
19 trate that small hydrophilic peptides at the picomole level can be desalted and characterized by matr
20 e level in solution-phase digests and at the picomole level in digests of samples separated on SDS-PA
22 ligosaccharides are detected at only the low picomole level with DHB, alternative matrices were scree
29 e ADHP-neoglycolipids are well retained, and picomole levels can be detected using monoclonal carbohy
31 full-scan electrospray mass spectra for low-picomole levels of cytochrome c contained in a 1536-well
34 ration range and can accurately quantify sub-picomole levels of released glycans, providing a needed
36 n PNA purity and sequence information at low picomole levels will be important as greater quality con
37 ntification of catechins at femtomole to low-picomole levels without extraction or sample pretreatmen
45 tein was detected at a concentration of 44.6 picomoles/mg protein, along with its redox partner NADPH
57 ay format, limits of detection down to a few picomoles of and excellent specificity for each dNTP aga
58 ar assembly yet examined; second, only a few picomoles of Arp2/3 was required for individual experime
59 polypeptides in a mixture, using only a few picomoles of each substrate and physiological amounts of
66 Thus, MAbs selectively identify and quantify picomoles of remaining protecting groups on antisense th
76 r hour of indole-3-acetyl-myo-inositol and 1 picomole per plant per hour of indole-3-acetic acid to t
77 onth-old normal and VPP mice were 425 +/- 90 picomoles per eye and 115 +/- 33 picomoles per eye, resp
80 al and hepatic sinusoidal insulin levels (in picomoles per liter) during the experimental period were
81 ontrols (median, 18.8 muIU/mL [to convert to picomoles per liter, multiply by 6.945]) and maternal sa
82 asting insulin (-2.75 muIU/mL [to convert to picomoles per liter, multiply by 6.945]; 95% CI, -4.50 t
83 94 muIU/mL; 95% CI, 1.28-2.61 [to convert to picomoles per liter, multiply by 6]; P < .001), glycated
87 it has a high specific activity of about 100 picomoles per minute per microgram in the presence of Ca
88 atmospheric mole fractions ranging from low picomoles per mol (ppt) to nanomoles per mol (ppb), depe
90 Technology (NIST) developed and reported on picomoles per mol standards containing 18 nonmethane hyd
93 alactoside in the endosperm supplies about 2 picomoles per plant per hour of indole-3-acetyl-myo-inos
95 face DMHg and the highest DMHg evasion (~9.4 picomoles per square meter per hour) found in upwelling
96 in burned animals at 7 days (125.4 +/- 15.5 picomoles [pmol]; p = .01) and at 14 days (216.7 +/- 50.
97 is fast (a few minutes) and operates best on picomole quantities of analyte in sample volumes less th
99 sults support the possibility of identifying picomole quantities of crosslinked peptides by similar s
103 tabilities rapidly and accurately using only picomole quantities of material and readily accessible l
104 id chromatography (HPLC) assay for measuring picomole quantities of nitrosothiol in biological sample
105 tly reported a simple procedure by which low picomole quantities of peptides can be modified to the c
107 lows the quantification of precursors at low picomole quantities with linear responses up to the nano
108 o allow analysis of biomolecules at nano- or picomole quantities, reducing the required amount of mat
109 osylation was directly identified in the low picomole range by collision-induced dissociation (CID) o
110 HLA)/peptide combinations in the nanomole to picomole range with minimal run time, reconciling the sy
112 tection and quantification, resulting in the picomole range, and sensitivity as well was not signific
115 pharmaceuticals is conducted at the nano- to picomole scale, conventional chemical characterization t
117 a valuable platform for the ultrasensitive, picomole-scale screening of small-molecule drugs against
119 We show that high-resolution NMR can reach picomole sensitivity for micromolar concentrations of an
122 between log ion intensity and quantity from picomole to femtomole amounts by liquid chromatography-e
123 were generated for concentrations in the low picomole to nanomole range, with correlation coefficient