ライフサイエンスコーパス: pituitary gland

1 neuropeptides from tissue in situ (i.e., rat pituitary gland).

2 atasets (brain; blood; thyroid, adrenal, and pituitary glands).

3 vate the promoters of genes expressed in the pituitary gland.

4 ifferentiate into the endocrine cells of the pituitary gland.

5 cell specification and in the adult anterior pituitary gland.

6 e's pouch to ensure the proper growth of the pituitary gland.

7 n that extends to and activates hGH-N in the pituitary gland.

8 ls, resulting in a greatly enlarged anterior pituitary gland.

9 ted to Rathke's pouch, the primordium of the pituitary gland.

10 tes the synthesis and release of GH from the pituitary gland.

11 thke's pouch, the progenitor of the anterior pituitary gland.

12 al for development of the mammalian anterior pituitary gland.

13 ulate the release of growth hormone from the pituitary gland.

14 and functional patterning of the vertebrate pituitary gland.

15 res via the median eminence to the posterior pituitary gland.

16 ction in IL-6-like material in the posterior pituitary gland.

17 ses through communication with the endocrine pituitary gland.

18 ithelial cells in the adenohypophysis of the pituitary gland.

19 cluding brain, skeletal muscle, and anterior pituitary gland.

20 sively expressed in the developing mammalian pituitary gland.

21 n in the liver, pancreas, heart, joints, and pituitary gland.

22 begin to differentiate within the developing pituitary gland.

23 the hormone-producing cells of the anterior pituitary gland.

24 hat SHH is required for proliferation of the pituitary gland.

25 ximity to the optic chiasm, hypothalamus and pituitary gland.

26 found to induce the production of GH by the pituitary gland.

27 eatic neuroendocrine cells, and the anterior pituitary gland.

28 beta subunit (LHbeta) gene expression in the pituitary gland.

29 y infiltration of T and B lymphocytes in the pituitary gland.

30 vere defects of the limbs, lung and anterior pituitary gland.

31 data suggest that the tumors arise from the pituitary gland.

32 same cells that contained DARPP-32-IR in the pituitary gland.

33 ng a loxP-modified SF1 locus in the anterior pituitary gland.

34 udy is to identify proton sensors in the rat pituitary gland.

35 ncludes the thyrotrope cells of the anterior pituitary gland.

36 ion of autoreactive T and B cells within the pituitary gland.

37 salivary gland, mammary gland, stomach, and pituitary gland.

38 thke's pouch, the primordium of the anterior pituitary gland.

39 ss elevated levels of CRH-BP in the anterior pituitary gland.

40 moderate levels in spinal cord, stomach, and pituitary gland.

41 growth hormone release from the rat anterior pituitary gland.

42 s to be present specifically in the anterior pituitary gland.

43 endocrine regulation since it innervates the pituitary gland.

44 ther T lymphocytes undergo activation in the pituitary gland.

45 ited to the thyrotrope cells of the anterior pituitary gland.

46 eloping and mature nervous system and in the pituitary gland.

47 a G-protein-coupled receptor, GnRHR, in the pituitary gland.

48 nce of ultradian oscillations in an isolated pituitary gland.

49 secretion through activation of GHSR in the pituitary gland.

50 stic mass involving the anterior lobe of the pituitary gland.

51 sequenced from the posterior lobe of the rat pituitary gland.

52 red for angiogenesis in the developing mouse pituitary gland.

53 including development of the brain, eyes and pituitary gland.

54 A axis, with the requirement of a functional pituitary gland.

55 ed its exclusive expression in the brain and pituitary gland.

56 marily centrally rather than at the anterior pituitary gland.

57 ge in the number of gonadotrope cells in the pituitary gland.

58 ted whether kisspeptins are expressed in the pituitary gland.

59 rgeted ablation of Jnk genes in the anterior pituitary gland.

60 f the anterior and intermediate lobes of the pituitary gland.

61 ing gonadotropin secretion from the anterior pituitary gland.

62 y differentiated endocrine cell types of the pituitary gland.

63 lipid rafts was also observed in whole mouse pituitary glands.

64 No OFQ was observed in the pineal or pituitary glands.

65 ells, and the pancreas and submandibular and pituitary glands.

66 37 surgical pituitary adenomas and 11 normal pituitary glands.

67 oteins (TDP-43, FUS, and ubiquilin) in human pituitary glands.

68 I 0.4-1.6]; mean dose 0.53 Gy [SD 1.40]) and pituitary gland (17 [3%] of 510, 1.1 [0.5-2.4] for more

69 (TSHbeta) in the pars tuberalis (PT) of the pituitary gland [2-4].

70 ioma, Rathke's cleft cyst, ectopic posterior pituitary gland), 5.melanin (metastatic melanoma), 6.les

71 ich are functional analogs to the vertebrate pituitary gland.(8-10) After mating, females steadfastly

72 g from the pars tuberalis (PT) region of the pituitary gland, a well-defined melatonin target site, c

73 ation that hormones produced in the anterior pituitary gland act as positive regulators of primary B

74 The anterior pituitary gland (adenohypophysis) comprises anterior and

75 e regulators of prolactin secretion from the pituitary gland, also release GABA within the hypothalam

76 Imprinted genes are highly expressed in the pituitary gland, among them, Dlk1, a paternally expresse

77 with a pronounced hypoplasia of the anterior pituitary gland and a marked decrease in pituitary and s

78 n radiation doses to the gonads, uterus, and pituitary gland and administered chemotherapy were quant

79 cretory granule content proteins of anterior pituitary gland and adrenal medulla.

80 n the control of developmental events in the pituitary gland and assign a critical role for hypothala

81 adrenomedullin (AM), is present in brain and pituitary gland and binds to the same receptors as AM an

82 one secretagogue receptor (GHS-R) from human pituitary gland and brain identified a third G protein-c

83 well as real data obtained from mouse liver, pituitary gland and data from NIH3T3, U2OS cell lines.

84 s to modify levels of Dlk1 expression in the pituitary gland and demonstrate that the dosage of DLK1

85 beta locus is readily detectable only in the pituitary gland and derived cell sources such as GH3 som

86 rms of transcript expression in the MBH, and pituitary gland and discovered the patterns were not syn

87 ell as expression in the developing anterior pituitary gland and first branchial arch.

88 and specific cell phenotypes in the anterior pituitary gland and in several other organs.

89 n (PRL)-producing lactotroph of the anterior pituitary gland and induce development of PRL-producing

90 denosine has been identified in the anterior pituitary gland and is secreted from cultured folliculos

91 signals that induce, pattern and specify the pituitary gland and its cell types.

92 tribution throughout the mammalian brain and pituitary gland and mediates a number of physiological f

93 ium is usually due to tumors in the anterior pituitary gland and occurs occasionally in hereditary mu

94 polypeptide hormone produced by the anterior pituitary gland and other sites that acts both systemica

95 receptors, each of which is expressed in the pituitary gland and other tissues.

96 e (eLH/CGbeta) that (1) is expressed in both pituitary gland and placenta, (2) encodes a characterist

97 locus in B cells distinct from those in the pituitary gland and placenta.

98 recently discovered protein, produced by the pituitary gland and secreted into the bloodstream.

99 acterized neurosecretory structures, the rat pituitary gland and single cultured Aplysia bag cell neu

100 red for correct development of the mammalian pituitary gland and spinal motoneurons.

101 namic contrast-enhanced MRI of the sella and pituitary gland and subsequent CT of the anterior skull

102 nRH include the gonadotropes of the anterior pituitary gland and the cells of various hormone-depende

103 is activity through negative feedback to the pituitary gland and the central nervous system (CNS).

104 rticotropin-releasing factor in the anterior pituitary gland and the central nervous system.

105 owth hormone secretagogues (GHSs) act on the pituitary gland and the hypothalamus to stimulate and am

106 the determination and differentiation of the pituitary gland and the ventral hypothalamus.

107 actin from lactotropic cells in the anterior pituitary gland and thus play a central role in prolacti

108 ination and proliferation events of anterior pituitary gland and tooth organogenesis.

109 (AH) is a rare inflammatory condition of the pituitary gland and usually affects women of childbearin

110 abnormalities in the developing hyoid bone, pituitary gland and vomeronasal organ.

111 , GHRH-R mRNA was analyzed in 2 normal human pituitary glands and 16 human pituitary adenomas using i

112 n (MALDI) MSI six nonpathological (NP) human pituitary glands and 45 hormone secreting and nonsecreti

113 and castrated rats without anterior or whole pituitary glands and were processed for histology and im

114 delta is highly expressed in salivary gland, pituitary gland, and adrenal gland, whereas p38alpha is

115 e, and in the rat is expressed in the brain, pituitary gland, and brown adipose tissue (BAT).

116 genitourinary tracts, developing cartilage, pituitary gland, and discrete regions of the central and

117 adult brain with a high concentration in the pituitary gland, and expression of Wnt10b was highest in

118 in target tissues e.g.: uterus, breast, and pituitary gland, and hormone-responsive tumors occur at

119 expresses in certain tissues, including the pituitary gland, and negatively regulates the LHbeta gen

120 on doses to the testes, ovaries, uterus, and pituitary gland, and related these to the risk of stillb

121 signaling in the formation of the vertebrate pituitary gland, and suggest that Hh signaling from neur

122 d in the ventral diencephalon and developing pituitary gland, and that Nxn deficient mice have pituit

123 1)C-dihydroergotamine in the choroid plexus, pituitary gland, and venous sinuses as expected from the

124 imilarity in the formation of the pineal and pituitary glands, and suggests that all CNS neuroendocri

125 d by a 50% threshold for all lesions and the pituitary gland; and for (18)F-FDG (C)-RD of SUVs of the

126 Subsequently, the anterior pituitary gland appears bifurcated, dysmorphic and occas

127 Prodynorphin (ProDYN) in the anterior pituitary gland appears to be processed differently from

128 ylamide gels, the soluble enzyme from bovine pituitary glands appears as two bands of 170 and 135 kDa

129 The intermediate and anterior lobes of the pituitary gland are derived from an invagination of oral

130 The anterior and intermediate lobes of the pituitary gland are formed from Rathke's pouch.

131 lts suggest that the actions of ANXA1 in the pituitary gland are independent of Fpr1 but may involve

132 otrophs and other cell types of the anterior pituitary gland are not well understood at present.

133 pulsatile release of gonadotropins from the pituitary gland are unknown.

134 required for the development of the anterior pituitary gland, are the predominant cause of MPHD (mult

135 Using the mouse pituitary gland as a model, the extraction protocol effe

136 cuate nucleus of the hypothalamus and in the pituitary gland as a model, we established a unique prot

137 s in up-regulation of both p53 and GH in the pituitary gland, as well as increased GH expression in n

138 r mechanisms underlying the formation of the pituitary gland, as well as the initial development of o

139 is not expressed in Rathke's pouch or in the pituitary gland at any time of embryogenesis.

140 ith a complete absence of vasculature in the pituitary gland at birth.

141 ts reveals that the dorsoventral axis of the pituitary gland becomes ventralized, with dorsal extensi

142 ated by the pars tuberalis (PT) of the fetal pituitary gland, before the fetal circadian system and a

143 The pineal and pituitary glands both expressed rhythms that persisted f

144 ressing tissues, that is, the uterus and the pituitary gland, both SUV and TBR showed high (18)F-FES

145 ne with mild lymphocytic infiltration in the pituitary gland but no clinical signs of hypophysitis, a

146 is expressed in the developing forebrain and pituitary gland, but its role during hypothalamo-pituita

147 low levels in several brain regions and the pituitary gland, but not in several peripheral tissues e

148 d1, is not expressed in the developing mouse pituitary gland, but rather in the mesenchyme surroundin

149 ow levels were also detected in the anterior pituitary gland by radioimmunoassay.

150 at adenosine, formed locally in the anterior pituitary gland can stimulate gap junction communication

151 Resection of the pituitary gland causes iatrogenic hypopituitarism which

152 pituitary development, we screened an adult pituitary gland cDNA library for homeobox sequences.

153 eus (SCN) and the pars tuberalis (PT) of the pituitary gland, collected every 4 h throughout 24 h, fr

154 only in the rostral ventral diencephalon and pituitary gland, commencing on e11.5, marks pituitary ce

155 , is essential for normal development of the pituitary gland, craniofacial region, eyes, heart, abdom

156 Null homozygotes exhibit arrest of pituitary gland development at the committed Rathke pouc

157 tein SC35 controls cell proliferation during pituitary gland development but is completely dispensabl

158 Pituitary gland development serves as an excellent model

159 During mammalian pituitary gland development, distinct cell types emerge

160 proliferation and cell-type determination in pituitary gland development.

161 meobox genes Rpx, Lhx3 and Pit1 for anterior pituitary gland development.

162 hine on the levels of dynorphin(1-13) in the pituitary gland, different brain regions, spinal cord an

163 uitarism (HR, 19.8; 95% CI, 5.4-72.9), other pituitary gland disorders (HR, 6.0; 95% CI, 1.2-30.2), d

164 During the development of the pituitary gland, distinct hormone-producing cell types a

165 box gene Six3 is expressed in the developing pituitary gland during mouse development but its functio

166 al ectoderm exhibit craniofacial defects and pituitary gland dysmorphology, but normal pituitary cell

167 n the rat, prolactin (PRL) from the anterior pituitary gland exerts its luteotropic function on the o

168 Pttg(-/-) pituitary glands exhibit ARF/p53/p21-dependent senescenc

169 racterize FSH glycosylation, FSH isoforms in pituitary gland extracts and a variety of physiological

170 x2 is expressed in both developing and adult pituitary gland, eye and brain tissues, suggesting an im

171 levels of thyroid-stimulating hormone in the pituitary gland), features found in Hashimoto's thyroidi

172 namic contrast-enhanced MRI of the sella and pituitary gland (Figs 1-3) and subsequent CT of the ante

173 odomain transcription factor is critical for pituitary gland formation and specification of the anter

174 has been proved to be essential for initial pituitary gland formation.

175 our FPR family members in the mouse anterior pituitary gland, Fpr-rs1, Fpr-rs2, Fpr-rs6, and Fpr-rs7.

176 We also analysed pituitary glands from individuals with Abeta pathology a

177 n, required to prevent induction of multiple pituitary glands from oral ectoderm.

178 nucleus of the hypothalamus (PVH) regulates pituitary gland function and feeding, and innervates aut

179 fied included genes involved in hypothalamic-pituitary gland functions.

180 In response to physiological demand, the pituitary gland generates new hormone-secreting cells fr

181 In the pituitary gland, GLAST is likely expressed by folliculo-

182 art because no pathologic examination of the pituitary gland has been reported to date.

183 After embolization therapy, pituitary gland height decreased and signal intensity vo

184 In the developing pituitary gland, Hlf was highly expressed in the rostral

185 while the circulating concentrations of the pituitary gland hormones vasopressin and adrenocorticotr

186 In the pituitary gland, hormones are stored in a functional amy

187 nt decrease in dynorphin(1-13) levels in the pituitary gland, hypothalamus, hippocampus, striatum, ce

188 protein and localized a specific area of the pituitary gland (i.e., adenohypophysis) known to secrete

189 ous syt isoforms are highly expressed in the pituitary gland in a lobe, and sex-specific manner.

190 revealed that myosin XV is expressed in the pituitary gland in both humans and mice.

191 yonic development of the hypothalamus and/or pituitary gland in humans results in congenital hypopitu

192 esions located in cerebellar hemispheres and pituitary gland in just one patient.

193 uterotonic agent known, is released from the pituitary gland in large amounts during parturition in a

194 M homeobox genes, determine formation of the pituitary gland in mice.

195 rise from the intermediate lobe cells of the pituitary gland in p27-/- mice, as well as in Rb+/- mice

196 nstrated it to be released from the anterior pituitary gland in vivo.

197 sent an expression profile of the developing pituitary gland including 83 transcripts, 40% of which a

198 ergic neurons and the vascular supply of the pituitary gland intact.

199 The anterior pituitary gland integrates the repertoire of hormonal si

200 suggest that serotonin plays a role in SENC/pituitary gland interaction.

201 ocin (OT) originates from secretion from the pituitary gland into the circulation and from absorption

202 The mammalian anterior pituitary gland is a compound endocrine organ that regul

203 The vertebrate pituitary gland is a key endocrine control organ that co

204 the dense cores of secretory granules of the pituitary gland is a Lubrol-insoluble aggregate.

205 The pituitary gland is an endocrine organ that is developmen

206 The anterior lobe of the pituitary gland is composed of five hormone-producing ce

207 dural AV fistula in the cavernous sinus, the pituitary gland is enlarged, which should not be misdiag

208 nt understanding of the role of PROP1 in the pituitary gland is limited to the repression and activat

209 fact that in the Six3-deficient embryos the pituitary gland is not induced.

210 The pituitary gland is particularly sensitive to genetic alt

211 tin (PRL) from the anterior lobe (AL) of the pituitary gland is tonically inhibited by dopamine (DA)

212 The pituitary gland is unique to Chordates, with significant

213 However, we demonstrate that the pituitary gland is vulnerable to iron deposition, and it

214 y, the broad physiological importance of the pituitary gland, its intriguing organogenesis, and the c

215 ere injected together there was no effect on pituitary gland, kidneys and spleen.

216 ayer of the cerebellum, and rostral anterior pituitary gland (location of corticotropes).

217 in effective imaging of the adrenal glands, pituitary gland, lymph nodes, pancreas, and thyroid and

218 t melatonin-receptor-containing cells in the pituitary gland may operate as key calendar cells, trans

219 on of these factors to tanycytes but not the pituitary gland, may explain the heterogeneous response

220 s obtained in vitro (binding affinity to rat pituitary gland membranes) and in vivo (rat antiovulator

221 by various immune cells and by the anterior pituitary gland, MIF plays a critical role in the system

222 n, expression of p8 mRNA in developing mouse pituitary glands mirrored its expression in the gonadotr

223 been shown to be secreted from the anterior pituitary gland, monocytes/macrophages, and T cells acti

224 rve sheath, optic disc, posterior globe, and pituitary gland morphology was performed and correlated

225 he endocrine system via the hypothalamus and pituitary gland, neuroendocrinology has evolved into a s

226 Total RNA isolated from the pituitary gland of a female white rhino was used as temp

227 ian eminence (ME) and various regions of the pituitary gland of OVX and OVX+NIL-D rats were measured

228 minergic neurons in the hypothalamus and the pituitary gland of the domestic pig, Sus scrofa, an anim

229 g evolution as SIX3 is also expressed in the pituitary gland of the human embryo.

230 ory granules were significantly decreased in pituitary glands of 4.1N(-/-) compared to 4.1N(+/+).

231 e (LH) beta subunit gene is expressed in the pituitary glands of all mammals, whereas the closely rel

232 L), but not growth hormone, was lower in the pituitary glands of mice with defective mammary gland de

233 In contrast, p8 mRNA was undetectable in the pituitary glands of normal adults.

234 We analyzed at autopsy the pituitary glands of six cancer patients treated with CTL

235 ly, reduced growth hormone expression in the pituitary glands of these mice.

236 Within the pituitary gland, only tyrosine hydroxylase fibers, and n

237 wing to organic disease of the hypothalamus, pituitary gland or testes has been treated with testoste

238 he hormone arginine vasopressin (AVP) in the pituitary gland or the hypothalamus, whereas nephrogenic

239 The endocrine-secreting lobe of the pituitary gland, or adenohypophysis, forms from cells at

240 The mammalian pituitary gland originates from two separate germinal ti

241 tg(-/-)p21(-/-) relative to Rb(+/-)Pttg(-/-) pituitary glands, p21-dependent senescence provoked by P

242 zation of contrast agents in the adrenal and pituitary glands, pancreas, and lymph nodes with depende

243 In the pituitary gland, peptide hormones can be stored as amylo

244 ligands for a receptor found in abundance in pituitary gland, play a broader role in brain function a

245 s involved in AVP release from the posterior pituitary gland, plays a role in the hypertension in RA+

246 cal defect in which the anterior lobe of the pituitary gland protrudes through the cartilage plate th

247 The pituitary gland regulates numerous physiological functio

248 (GH), a pleiotropic hormone secreted by the pituitary gland, regulates immune and inflammatory respo

249 Cushing disease is a condition in which the pituitary gland releases excessive adrenocorticotropic h

250 of the vertebrate neuroendocrine system, the pituitary gland relies on the progressive and coordinate

251 el role for 4.1N in the axis of hypothalamus-pituitary gland-reproductive system.

252 Normal development of the pituitary gland requires coordination between the mainte

253 Examination of pituitary glands revealed that the secretory granules we

254 Within the anterior pituitary gland, RXRgamma expression is limited primaril

255 stem cell commitment with lifelong impact on pituitary gland size.

256 nificantly reduced body weights and anterior pituitary gland sizes.

257 acellular compartment to the cell surface in pituitary gland somatotropes, concomitant with increasin

258 During development of the mammalian pituitary gland specific hormone-producing cell types, c

259 The pituitary gland, spleen, and thymus are disproportionate

260 at staining was consistently observed in the pituitary glands, stomach, and intestines, and to a less

261 reatment (uterus: SUV -21.5% and TBR -37.9%; pituitary gland: SUV -14.2% and TBR -26.0%, compared wit

262 interim (uterus: SUV -50.6% and TBR -58.5%; pituitary gland: SUV -39.0% and TBR -48.3%), which tende

263 galactosidase was enhanced in Pttg-deficient pituitary glands, telomere lengths were increased.

264 Here, we used the anterior pituitary gland that harbors different interdigitated ho

265 s a peptide hormone produced by the anterior pituitary gland that is critical in lactation.

266 defined as impaired production of GH by the pituitary gland that results in growth failure.

267 Prolactin is a major hormone product of the pituitary gland, the central endocrine regulator.

268 timulate the release of GH from the anterior pituitary gland through the activation of a novel G-prot

269 growth hormone secretagogue receptor in the pituitary gland, thus fulfilling criteria of a brain-gut

270 gulator of developmental angiogenesis in the pituitary gland, thus providing insight into the long-st

271 at determine the tumorigenic response of the pituitary gland to estrogens.

272 y is indicative of a failure of the anterior pituitary gland to stimulate the target endocrine organs

273 We report a catalog of the mouse embryonic pituitary gland transcriptome consisting of five cDNA li

274 A surge of luteinizing hormone (LH) from the pituitary gland triggers ovulation, oocyte maturation, a

275 Patients with craniopharyngeoma or a pituitary gland tumor were excluded.

276 During the development of the pituitary gland, two highly related paired-like homeodom

277 Endocrine cells in the pituitary gland typically display either spiking or burs

278 n of the hormone-secreting cell types of the pituitary gland underlie severe forms of CPHD.

279 SHH) in outgrowth and differentiation of the pituitary gland using loss- and gain-of-function studies

280 nctional pituitary adenomas and eight normal pituitary glands, using 33 oligonucleotide GeneChip micr

281 araventricular nucleus [PVN]) but not in the pituitary gland, ventromedial hypothalamus, dorsal hippo

282 The mean height of the pituitary gland was 9.4 mm +/- 1.5 (standard deviation)

283 We observed that a reduced volume in the pituitary gland was associated with the slope of neuroti

284 The superior contour of the pituitary gland was convex or flat in group 1 and flat o

285 A growth-promoting principle of the pituitary gland was discovered in 1921, and bovine growt

286 des, significant radioactivity uptake in the pituitary gland was observed (SUV of 0.7 at 30 min pi).

287 of ProDYN in both the anterior and posterior pituitary glands was much lower than that in the neural

288 ) release from the hypothalamus and anterior pituitary gland, we hypothesized that it also might rele

289 termediate (IL) and neural (NL) lobes of the pituitary gland were determined by HPLC-EC.

290 termediate (IL) and neural (NL) lobes of the pituitary gland were dissected and the concentration of

291 The weight of both thyroid and pituitary glands were significantly less in hypothyroid

292 y unique, actions also occur in the anterior pituitary gland where both peptides inhibit adrenocortic

293 iating ANXA1 actions, we have focused on the pituitary gland, where ANXA1 has a well-defined role as

294 s including adrenal gland, kidney, brain and pituitary gland, where it acts to modify sodium homeosta

295 ly innervating different brain areas and the pituitary gland, which could represent an important fact

296 but rather in the mesenchyme surrounding the pituitary gland, which is an essential source of signali

297 similar across brain regions except for the pituitary gland, which is not protected by the BBB.

298 of plasma growth hormone (GH) release by the pituitary gland, which shows significant sex differences

299 e head and orbits demonstrated an asymmetric pituitary gland without chiasm compression and discrete

300 mation and maturation of blood cells, in the pituitary gland (Wnt10a), and in the face, limbs and ski