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1 in sensitivity analyses (eg, when excluding placebo-controlled studies).
2 was a multicenter, randomized, double-blind, placebo-controlled study.
3 ients from healthy donors in a double-blind, placebo-controlled study.
4 were investigated in a pilot, double-blind, placebo-controlled study.
5 se of patients treated with ivacaftor in the placebo-controlled study.
6 that of patients who received placebo in the placebo-controlled study.
7 nts who had received active treatment in the placebo-controlled study.
8 Randomized, double-blind, placebo-controlled study.
9 o Bolivian Leishmania (v.) braziliensis in a placebo-controlled study.
10 This was a randomized placebo-controlled study.
11 eers underwent a randomized, double-blinded, placebo-controlled study.
12 d in a phase I, double-blind, multiple-dose, placebo-controlled study.
13 lled in a 6-month, randomised, double-blind, placebo-controlled study.
14 igation was a within-subjects, double-blind, placebo-controlled study.
15 , an event-driven, randomized, double-blind, placebo-controlled study.
16 in a randomized, three-armed, double-blind, placebo-controlled study.
17 rom CSU patients enrolled in a double-blind, placebo-controlled study.
18 III, randomized, double-masked, multicenter, placebo-controlled study.
19 horea, was well tolerated in a double-blind, placebo-controlled study.
20 II in case studies, cohort studies, and one placebo-controlled study.
21 owel syndrome in a randomised, double-blind, placebo-controlled study.
22 , prospective, 1:1 randomized, double-blind, placebo-controlled study.
23 EBV shedding in a randomized, double-blind, placebo-controlled study.
24 This was a randomized, double-blind, placebo-controlled study.
25 eart failure attended a series of randomized placebo-controlled studies.
26 se in two parallel, identical, double-blind, placebo-controlled studies.
27 ed recent-onset AF and was well tolerated in placebo-controlled studies.
28 ted in a series of randomized, double-blind, placebo-controlled studies.
29 ent will be determined by ongoing randomized placebo-controlled studies.
30 > or = 65 years, using data pooled from two placebo-controlled studies.
31 systematic evaluation in large, randomized, placebo-controlled studies.
32 an AE profile consistent with those seen in placebo-controlled studies.
33 In this double-blind, randomized, crossover, placebo-controlled study, 15 subjects with DSM-IV bipola
34 AND PARTICIPANTS: In a phase 2 double-blind, placebo-controlled study, 159 patients (median [SD] age,
36 In this double-blind, randomized, crossover, placebo-controlled study, 22 subjects with DSM-IV treatm
37 -month dose-response randomized double-blind placebo-controlled study, 221 polysensitized subjects wi
38 e II, multicentre, randomised, double-blind, placebo-controlled study, 249 patients with RRMS, aged 1
48 this multicenter, double-blind, randomized, placebo-controlled study, 74 participants with peanut al
49 s.In this 12-wk, double-blinded, randomized, placebo-controlled study, 76 vegans received either a pl
50 In this phase III, parallel, double-blind, placebo-controlled study, 766 patients with moderate-to-
53 this multicentre, randomised, double-blind, placebo-controlled study, adult patients with definite N
54 In this phase III, randomised, double-blind, placebo-controlled study, adults from 63 sites in 23 cou
57 ransmembrane conductance regulator (CFTR) in placebo-controlled studies and patients aged 6-11 years
58 d onto a phase III, multicenter, randomized, placebo-controlled study and administered placebo or DA
59 luded 2 studies: a randomized, double-blind, placebo-controlled study and an open-label extension stu
60 re of 4-6 were randomized in a double-blind, placebo-controlled study, and 488 of these patients rece
61 dose (25-1200 mg), double-blind, randomised, placebo-controlled study, and part 2, an open-label, ran
68 quate follow-up and in particular randomized placebo-controlled studies are required to confirm these
71 ofile of REG1 in a randomized, double-blind, placebo-controlled study, assigning 50 subjects with cor
72 nter, prospective, randomized, double-blind, placebo-controlled study at 2 tertiary medical centers o
75 icentre, parallel, randomised, double-blind, placebo-controlled study at 37 sites (hospitals and spec
77 is randomised, double-blind, parallel-group, placebo-controlled study at 49 hospitals in seven Europe
78 We did a phase 2, randomised, double-blind, placebo-controlled study at 51 centres in the USA, Canad
81 Conclusion: In this 12-week, randomized, placebo-controlled study, cilofexor was well tolerated a
82 ulin regulation of lipolysis.A double-blind, placebo-controlled study compared 6 mo of 3.9 g eicosape
83 participating in a randomized, double-blind, placebo-controlled study comparing 28 weeks of IPT antep
84 disease onset in a total of four randomized, placebo-controlled studies conducted in rabbits and monk
86 rbamazepine, was assessed in a double-blind, placebo-controlled study conducted from September 2014 t
88 ere assessed in a multicentre, double-blind, placebo-controlled study conducted in 483 patients with
89 were included in a randomized, double-blind, placebo-controlled study conducted in Switzerland betwee
99 ye Disease Study 2 (AREDS2) is a randomized, placebo-controlled study designed to determine whether s
100 RN-HIV) trial is a randomized, double-blind, placebo-controlled study, designed to investigate the ef
101 T was a three-part, randomised, multicentre, placebo-controlled study done at 22 centres in the USA,
102 IT2 was a two part, randomised, multicentre, placebo-controlled study done at 38 centres in 12 countr
103 RISE-IIP was a double-blind, randomised, placebo-controlled study done at 65 pulmonary hypertensi
104 this multicentre, double-blind, randomised, placebo-controlled study done in 48 acute care hospitals
105 In this phase 3, randomised, observer-blind, placebo-controlled study, done at 77 centres worldwide,
107 In this phase 3, randomised, double-blind, placebo-controlled study, eligible patients aged 2-65 ye
108 Methods: This prospective, double-blind, placebo-controlled study enrolled 10 patients with bioch
109 III, double-blind, randomized, multicenter, placebo-controlled study, established the efficacy and s
110 (ACT)-1 and ACT-2 randomized, double-blind, placebo-controlled studies evaluated infliximab inductio
111 A multicenter, randomized, double-blind, placebo-controlled study evaluated 3 regimens of grass a
115 This phase II randomized, double-blinded, placebo-controlled study evaluated the efficacy of vorin
117 multicenter, randomized (1:1), double-blind, placebo-controlled study evaluated the safety and effica
118 uninfected adults were enrolled in 6 blinded placebo-controlled studies evaluating the immunogenicity
119 was a multicenter, randomized, double-blind, placebo-controlled study evaluating quinapril 80 mg/day,
122 GVHD treatment; however, recent randomized, placebo-controlled studies failed to corroborate these r
123 s, and carried out a double-blind randomized placebo-controlled study for 16 weeks, followed by an op
125 2000, a series of 10 individual double-blind placebo-controlled studies has evaluated newer antidepre
132 In a phase 1, double-blinded, randomized, placebo-controlled study, healthy subjects were inoculat
135 ve days in a single-blind (patients masked), placebo-controlled study in 12 men with clinically stabl
136 is a multicentre, randomised, double-blind, placebo-controlled study in 3323 women with stage 1-3 br
139 We conducted a randomized, double-blind, placebo-controlled study in 77 subjects with diabetic ne
140 was a phase 1/2, randomized, observer-blind, placebo-controlled study in adults with multiple myeloma
141 did a multicentre, double-blind, randomised, placebo-controlled study in four hospitals in Kenya (two
144 , an event-driven, randomized, double-blind, placebo-controlled study in patients hospitalized for he
145 , and had a good safety profile in a phase 3 placebo-controlled study in patients with advanced non-s
146 in a multicenter, randomized, double-blind, placebo-controlled study in patients with biopsy-confirm
148 ticentre, phase 3, randomised, double-blind, placebo-controlled study in patients with tuberous scler
151 a randomized, double-blind, counterbalanced, placebo-controlled study in which we administered the br
152 This prospective, randomized, double blind, placebo-controlled study included 30 patients randomised
154 e 2, multi-center, randomized, double-blind, placebo-controlled study included a 12-week treatment ph
155 e II, multicenter, randomized, double-blind, placebo-controlled study included the following: a 12-we
157 e-center, phase 2, randomized, double-blind, placebo-controlled study investigated the safety, tolera
158 a first-in-human, randomized, double-blind, placebo-controlled study investigating the safety, toler
160 atients; a phase 3 randomized, double blind, placebo controlled study involving 186 patients; an open
161 a from a series of randomized, double-blind, placebo-controlled studies involving subjects with unipo
162 TIENTS: A phase 1 and 2 randomized, blinded, placebo-controlled study involving 65 patients with isch
163 this multicenter, randomized, double-blind, placebo-controlled study involving 66 patients, we evalu
164 RA), in a phase 2, randomized, double-blind, placebo-controlled study involving patients with psoriat
165 gnetic resonance imaging (MRI) in a phase 2, placebo-controlled study involving patients with relapsi
168 In this phase 3, double-blind, randomised, placebo-controlled study, men with non-metastatic castra
169 collected from two randomized double-blind, placebo-controlled studies: MENSA (NCT01691521: 32-week
175 25, 2015, from two randomised, double-blind, placebo-controlled studies of at least 32 weeks duration
176 Results were integrated from 2 double-blind, placebo-controlled studies of ecallantide treatment for
177 e field is strongly supported by blinded and placebo-controlled studies of IL-5 and oral viscous bude
178 bility data from 2 double-blind, randomized, placebo-controlled studies of infliximab plus methotrexa
179 was pooled from three phase III randomized, placebo-controlled studies of pirfenidone for IPF (the t
181 med a randomized Phase I/II, observer-blind, placebo-controlled study of 12 healthy, H pylori-negativ
182 -day, multicenter, randomized, double-blind, placebo-controlled study of 155 patients with nonconstip
183 A multicenter, randomized, double-blind, placebo-controlled study of 161 children and adolescents
185 , and Participants: Multicenter double-blind placebo-controlled study of 260 nonneutropenic, nontrans
186 rformed a 10-week, randomized, double-blind, placebo-controlled study of 281 patients with mildly to
187 a phase 1, randomized, partial double-blind, placebo-controlled study of 36 malaria-naive adults, all
188 a Phase I, randomized, partial double-blind, placebo-controlled study of 36 malaria-naive adults, all
189 med a randomized, double-blind, multicenter, placebo-controlled study of 420 patients with IBS-C give
190 We performed a randomized, double-blind, placebo-controlled study of 44 adults with IBS and diarr
191 onal and nonlesional skin in a double-blind, placebo-controlled study of 54 patients with moderate to
192 We conducted a randomized, double-blind, placebo-controlled study of 66 optimally-treated T2DM pa
194 Multicenter, randomized, double-masked, placebo-controlled study of acetazolamide in 165 partici
196 confirmed this prediction empirically with a placebo-controlled study of cholinesterase inhibition.
197 participants of a randomized, double-blind, placebo-controlled study of daclizumab (DZB) and mycophe
198 viously reported the results of a randomized placebo-controlled study of egg oral immunotherapy (eOIT
199 reported the results of a 1-y double-blind, placebo-controlled study of embryonic dopamine cell impl
200 costeroid-sparing effects in a double-blind, placebo-controlled study of FIP1L1/PDGFRA-negative, cort
202 We conducted a randomized, double-blind, placebo-controlled study of IPTp comparing the standard
203 We conducted a randomized, double-blind, placebo-controlled study of lebrikizumab, a monoclonal a
204 is the standard treatment, yet no randomized placebo-controlled study of medical IOP reduction has be
205 harmacotherapy, a large, recently completed, placebo-controlled study of methylphenidate for preschoo
206 his was a 12-week, double-blind, randomized, placebo-controlled study of NAC in children with autisti
207 We conducted a double-blind, randomized, placebo-controlled study of nasal responses to live atte
208 rst year of life.A double-blind, randomized, placebo-controlled study of newborn infants assigned to
210 ded this work in a randomized, double-blind, placebo-controlled study of patients with bipolar depres
211 We undertook this phase 3, double-blind, placebo-controlled study of patients with hepatocellular
213 ELBW; <1000 g) participating in a randomized placebo-controlled study of probiotic supplementation.
215 atients who completed a 30-month randomized, placebo-controlled study of the effect of doxycycline on
216 nvestigated this hypothesis in a prospective placebo-controlled study of treated patients with hypert
217 We performed a randomized, double-blind, placebo-controlled study of two neutralizing, fully huma
218 e, randomized, double-blinded, double-dummy, placebo-controlled study of vitamin D(3) supplementation
221 zed, single-centre, double-blind, crossover, placebo-controlled study, partial responders taking opti
222 In this phase 2A double-blind, randomised, placebo-controlled study, patients aged 18 years or olde
223 ot investigation followed by a double-blind, placebo-controlled study, patients with allergic rhiniti
228 To date, there have been no randomized, placebo-controlled studies supporting the efficacy of an
230 and ARIES-2 trials were the pivotal 12-week, placebo-controlled studies that led to the regulatory ap
231 RD-5: two phase 3, randomized, double-blind, placebo-controlled studies that utilized the same sequen
232 ucted two phase 3, randomized, double-blind, placebo-controlled studies that were designed to assess
240 y QOL-B-RSS, suggesting a continued need for placebo-controlled studies to establish the clinical ben
241 patients were randomized in a double-blind, placebo-controlled study to assess pseudobulbar affect w
242 nducted a 6-month, randomized, double-blind, placebo-controlled study to assess safety, tolerability,
244 We conducted a randomized, double-blind, placebo-controlled study to assess whether raltegravir i
248 We conducted a double-blind, randomized, placebo-controlled study to evaluate the effect of gallo
249 A I was a 40-week, randomized, double-blind, placebo-controlled study to evaluate the efficacy and sa
252 We conducted a randomized, double-blind, placebo-controlled study to examine whether pioglitazone
253 performed a post hoc analysis of a phase III placebo-controlled study to identify characteristics of
254 ed a parallel, double-blind, randomized, and placebo-controlled study to investigate the effect of ph
255 en season were randomized in a double-blind, placebo-controlled study to receive 300IR 5-grass pollen
256 rhinitis were randomized in a double-blind, placebo-controlled study to receive 500 index of reactiv
257 were enrolled in a randomized, double-blind, placebo-controlled study to receive IV methylprednisolon
259 were enrolled into a randomized double-blind placebo-controlled study using 4 weeks of slow-release m
262 IIb, randomized, parallel-arm, double-blind, placebo-controlled study was conducted at 49 centers in
265 se 2, multicenter, randomized, double-blind, placebo-controlled study was conducted in 138 patients w
268 ternational, randomized (2:1), double-blind, placebo-controlled study was conducted to compare comple
269 h factor Xa inhibitor, a two-part randomized placebo-controlled study was conducted to evaluate andex
272 This three-stage randomised, double-blind, placebo-controlled study was done at 59 clinical sites i
275 this prospective, randomized, double-blind, placebo-controlled study was to compare the effect of de
276 f this multicenter, prospective, randomized, placebo-controlled study was to evaluate and compare the
277 The aim of this randomized, double-blind, placebo-controlled study was to test the hypothesis that
281 this multicenter, randomized, double-blind, placebo-controlled study, we assessed larazotide acetate
282 In our 6 week, randomised, double-blind, placebo-controlled study, we enrolled adults (aged >/=40
283 ase 2 multicentre, randomised, double-blind, placebo-controlled study, we enrolled participants aged
286 se 3, multicenter, randomized, double-blind, placebo-controlled study, we randomly assigned 261 patie
290 In our phase 3, randomized, double-blind, placebo-controlled study, we randomly assigned 921 patie
291 In this phase 3, multicentre, randomised, placebo-controlled study, we randomly assigned adults wi
294 In this phase 2 randomised, double-blind placebo-controlled study, we recruited healthy adults (>
295 icentre, parallel, randomised, double-blind, placebo-controlled study, we recruited patients aged 18-
298 We conducted a multicenter, randomized, placebo-controlled study with a 2-week single-blind run-
299 were enrolled in a double-blind, randomized, placebo-controlled study with pexacerfont (300 mg/day fo
300 sessed this hypothesis via a double-blinded, placebo-controlled study with the dopamine receptor agon