ライフサイエンスコーパス: plasmid

1 onal distribution of the resistance-encoding plasmid.

2 nockout is combined with insertion of a pAID plasmid.

3 with four fluorescent reporters coded by one plasmid.

4 resist acquisition of a second copy of said plasmid.

5 which we constructed the synthetic screening plasmid.

6 nly the transposon but also the entire donor plasmid.

7 ining terminally gapped, linearized reporter plasmid.

8 mple insertions and integration of the donor plasmid.

9 ited strains after curing of the base editor plasmid.

10 n in small intestine was highly dependent on plasmid.

11 asites, including bacteriophages/viruses and plasmids.

12 NA and transient expression from transfected plasmids.

13 redicts the persistence and abundance of any plasmids.

14 which frequently are encoded on conjugative plasmids.

15 SLC7A5 or Slc7a5 short hairpin RNA encoding plasmids.

16 TtAgo defends against transformation by DNA plasmids.

17 the conjugative, beta-lactamase and cryptic plasmids.

18 h their prevalence and co-linkage to certain plasmids.

19 rs enables identification of the transferred plasmids.

20 electroporation of Cas9 and single guide RNA plasmids.

21 ce the spread of these multi-drug-resistance plasmids.

22 ting a role for Acrs in the dissemination of plasmids.

23 mportance of CRISPR-mediated defence against plasmids.

24 genetic invaders such as bacteriophages and plasmids.

25 ntisense oligonucleotides and overexpression plasmids.

26 e-series data revealed that the variation in plasmid abundance over time explained more of the observ

27 Our findings suggest plasmid acquisition in the gastrointestinal tract to be

28 ession of the homology-directed repair donor plasmid along with the P(C) Celtic allele.

29 are amalgamations of at least one ancestral plasmid and a bacteriophage.

30 erfere directly with the replication of both plasmid and chromosomal DNA.

31 catabolic pathway are separately located on plasmid and chromosome indicates that recent assembly an

32 erms of Single Strand Break (SSB) yields for plasmid and Double Strand Break (DSB) yields for plasmid

33 aptation, but also maintenance of horizontal plasmid and intron transfer under cold-shock.

34 a detailed protocol to (i) generate complex plasmid and lentivirus CellTag libraries for labeling of

35 ystem capable of acquiring guide RNAs to new plasmid and phage targets and a second providing long-te

36 horizontal transfer of the conjugative pRS01 plasmid and stimulates retrotransposition of the intron.

37 library consists currently of more than 2600 plasmids and 1700 fly lines with a focus on targeting ki

38 an improved Cas9 plasmid with multiple sgRNA plasmids and an efficient screening procedure to identif

39 veloped a strategy to characterize virulence plasmids and applied it to analyze hundreds of strains c

40 c elements and suppresses the propagation of plasmids and infection by phages.

41 le and spacers are acquired from transferred plasmids and permanently stored in genomic CRISPR arrays

42 h horizontal gene transfer (HGT) mediated by plasmids and plasmid-borne transposable elements.

43 rey thereby halving the number of expression plasmids and recombinant proteins required for screening

44 cerevisiae strains that lack endogenous 2mu plasmids and reproducibly inhibit mitotic plasmid stabil

45 microbial consortia transferring mobilizable plasmids and with quantitative data available in the lit

46 oter for a heat-inducible transposase helper plasmid, and creating vectors marked with the D. melanog

47 surements to compare translocation of phage, plasmid, and synthetic A-philic, GC rich sequences by th

48 Plasmids are a foundational tool for basic and applied r

49 Current chlamydial plasmids are amalgamations of at least one ancestral pla

50 ombination, it was surprising that oncogenic plasmids are descended from a few conserved lineages.

51 Plasmids are important in microbial evolution and adapta

52 Furthermore, AMR plasmids are significantly more prevalent in gonococci f

53 By contrast, plasmids are usually excluded or analyzed with low-resol

54 Plasmids are vehicles for horizontal gene transfer betwe

55 omic and phylogenetic analyses, we show that plasmids are widespread in a collection of 3724 gonococc

56 The MSN provides efficient loading of Cas9 plasmid as well as Cas9 protein/guide RNA ribonucleoprot

57 lying on and developing massive libraries of plasmids as vectors for directed evolution, combinatoria

58 d rapid transgene expression kinetics of GFP plasmids at no compromise of cell viability.

59 hromatin, eliminating the issues raised with plasmid-based approaches.

60 Conversely, plasmid-based constructs do not demonstrate such repress

61 these classic genetic methods, we describe a plasmid-based library methodology that affords bidirecti

62 nd FZD10, and miR-153-3p sequestration via a plasmid-based miR inhibitor system attenuated Wnt signal

63 The effects are seen here in plasmid-based recombination assays and in vivo cloning p

64 e independent of distance and orientation in plasmid-based reporter assays of gene expression.

65 possibility of using the recently developed plasmid-based rotavirus reverse genetics (RG) system to

66 ration in mammalian cells, recombining donor plasmids bearing the attB recognition site with introduc

67 ct that Type III immunity can be provided by plasmid-borne mini-arrays open ways for genomic manipula

68 Both are plasmid-borne ORFs, carried by pBCA072 for B. cenocepaci

69 was transformed to 3,4-dichloromuconate by a plasmid-borne ring-cleavage chlorocatechol 1,2-dioxygena

70 gene transfer (HGT) mediated by plasmids and plasmid-borne transposable elements.

71 in" based on the presence of an eleven-gene, plasmid-borne, virulence cluster of sulfur redox genes.

72 ucture and dynamics of over 10,000 bacterial plasmids, by quantifying their genetic similarities and

73 Yet, carrying a plasmid can be costly, and long-term association of plas

74 Plasmids can horizontally transmit genetic traits, enabl

75 tween bacteria, and in Neisseria gonorrhoeae plasmids can mediate high-level antimicrobial resistance

76 Conjugative plasmids can mediate the spread and maintenance of diver

77 ommon mechanism for the replication of small plasmids carrying antibiotic resistance genes in Gram-po

78 n them have led to a complex array of mosaic plasmids carrying bla (KPC) Taken altogether, these resu

79 provides a significant fitness advantage to plasmid-carrying cells.

80 we show one such stabilizing factor is host-plasmid coevolution under antibiotic selection, which fa

81 by selection for genomic incorporation of a plasmid coexpressing BC200 and the neomycin resistance g

82 ment in the cloud including simple mutant or plasmid collections and purchase-tracking databases.

83 eater plasmid persistence in both novel host-plasmid combinations and, in some cases, multi-plasmid h

84 omic analysis indicates that: 1) these large plasmids comprise an emerging family present in differen

85 Although aspects of IncC plasmid conjugation have been well studied(4-9), many ro

86 escribe approaches for introducing exogenous plasmid constructs and for sparse cell labeling to image

87 tive amino lipid ECO and a therapeutic ABCA4 plasmid containing rhodopsin promoter (pRHO-ABCA4).

88 d gplas, a new approach to reliably separate plasmid contigs into discrete components using sequence

89 amework for the much needed incorporation of plasmid data into genomic surveillance systems, an essen

90 However, to our surprise, plasmid-deficient Chlamydia failed to produce infectious

91 oculation that bypasses the gastric barrier, plasmid-deficient Chlamydia produced infectious progenie

92 ted, continent-wide study of chromosomal and plasmid diversity.

93 roxyethyl acrylate that effectively compacts plasmid DNA (pDNA) through electrostatic binding and int

94 The present work develops a plasmid DNA approach to gene therapy of NPC1 using Troja

95 4(+) T cells expressed cGAS and responded to plasmid DNA by upregulation of ISGs and release of bioac

96 We found that site-specific mutations in plasmid DNA can be generated in Escherichia coli using m

97 This study examines the fate of plasmid DNA carrying ampicillin and tetracycline resista

98 AS-dependent cell-intrinsic response to both plasmid DNA challenge or inoculation with HSV-1DeltaUL41

99 BALB/c mice were immunized i.m. with plasmid DNA encoding a model Ag HIV-1 Env gp140 and sele

100 ity and eTE were systematically explored for plasmid DNA encoding green fluorescent protein following

101 THLs were encapsulated with a 8.0 kb plasmid DNA encoding the 3.9 kb human NPC1 open reading

102 mia that hydrodynamic tail-vein injection of plasmid DNA encoding the adenine base editor (ABE) and a

103 li (E coli) containing plasmids, followed by plasmid DNA extraction and purification prior to downstr

104 Plasmid DNA incubated in aged urine resulted in a >2 log

105 Plasmid DNA is a promising vaccine platform that togethe

106 g Trojan horse liposomes (THLs), wherein the plasmid DNA is encapsulated in 100 nm pegylated liposome

107 ies, phiC31 integrase has been introduced as plasmid DNA or mRNA.

108 When the plasmid DNA was incubated in aged urine that had been fi

109 nthetic nanonucleases, able to cleave pBR322 plasmid DNA with the highest efficiency reported so far

110 y when it is tested against the real target (plasmid DNA).

111 he NPC1(-/-) null mouse, and delivery of the plasmid DNA, and NPC1 mRNA expression in brain, spleen,

112 In mouse T cells, cGAS KO ablated sensing of plasmid DNA, and TREX1 KO enabled cells to sense short i

113 to target PCR-derived linear double-stranded plasmid DNA.

114 We transfected various source cells with plasmid DNAs and stimulated the cells with a focal and t

115 involvement in HDR between a Cas9 DSB and a plasmid double stranded donor DNA (dsDonor).

116 The IncC family of broad-host-range plasmids enables the spread of antibiotic resistance gen

117 ressed from bacteria transformed with pET20b plasmid encoded with CD200 extracellular domain and core

118 The T6SS genes in Campylobacter plasmids encoded genes and proteins that were similar to

119 -copy number bacterial plasmids is driven by plasmid-encoded ATPases that are represented by the P1 p

120 gRNA into the host cytoplasm requires the F-plasmid-encoded coupling protein, TraD, which is located

121 y inoculated Chlamydia sp. deficient in only plasmid-encoded pGP3 was no longer able to colonize the

122 exclusively of either chromosome-encoded or plasmid-encoded proteins.

123 resent in B. subtilis NCIB 3610 and that the plasmid-encoded RNase HI contributes to chromosome stabi

124 A plasmid-encoded signalling peptide, Phr*pLS20, inactivat

125 A lower dose of 1 mg/kg of 2-12C or a DNA plasmid-encoded version of 2-12C reduced pathology and v

126 Using a plasmid encoding an anti-poxvirus monoclonal antibody (a

127 g human embryonic kidney (HEK293) cells with plasmids encoding both SaCas9 and an individual sgRNA.

128 , mice were sequentially vaccinated with DNA plasmids encoding capsid proteins of different RV A type

129 l isolates and allows a detailed analysis of plasmid epidemiology based solely on short-read sequence

130 te suppression of plasmid replication and/or plasmid eviction in multiple orthogonal readouts and pot

131 a second directing transposition into mobile plasmids facilitating cell-to-cell transfer.

132 growing Escherichia coli (E coli) containing plasmids, followed by plasmid DNA extraction and purific

133 Our vector series, pGTag (plasmids for Gene Tagging), contains reporters flanked b

134 and that CNSC harbor carbapenemase-encoding plasmids found in other Enterobacterales.

135 mydia sp. survived significantly better than plasmid-free Chlamydia sp. in small intestinal tissues.

136 rge intestine, although similarly inoculated plasmid-free Chlamydia sp. was able to do so.

137 culated into the same mouse small intestine, plasmid-free Chlamydia sp. was no longer able to spread

138 Nevertheless, orally inoculated plasmid-free Chlamydia sp. was still able to colonize th

139 m, against a strain carrying the large, pCRE plasmid from which we constructed the synthetic screenin

140 ations, such as the inability to distinguish plasmids from each other in a bacterial genome.

141 genomics projects but the reconstruction of plasmids from these data is facing severe limitations, s

142 plasmids into cliques, which correlate with plasmid gene content, bacterial host range, GC content,

143 The most conserved plasmid gene families are predominantly vertically inher

144 nantly vertically inherited, while accessory plasmid gene families show significantly increased mobil

145 eeded to characterize the mechanism by which plasmid genes determine vancomycin susceptibility in C d

146 Transfecting K562 cells with a reporter plasmid harboring the TOP2alpha/170 3'-UTR together with

147 nd was common in two highly stable IncI1 MDR plasmids harbouring (bla(CTX-M-1),sul2, tetA) or (bla(CT

148 Pseudomonas phages and plasmids have taken advantage of this regulatory scheme

149 lasmids, which include pKpQIL-like and IncX3 plasmids, have a long association (and are coevolving) w

150 Community-scale CRISPR-based plasmid-host and phage-host interaction networks reveale

151 asmid combinations and, in some cases, multi-plasmid hosts.

152 mid and Double Strand Break (DSB) yields for plasmid/human cell.

153 II is important for chromosome stability and plasmid hyper-replication.

154 c immune systems provide anti-viral and anti-plasmid immunity via a dual mechanism of RNA and DNA des

155 Csx1 can effectively direct successful anti-plasmid immunity.

156 s paired with OG within the context of a DNA plasmid in bacteria.

157 intestine, indicating a critical role of the plasmid in chlamydial differentiation into infectious pa

158 reak site was restored in the recircularized plasmid in control cells by using the endogenous homolog

159 then tracked the appearance of ten different plasmids in all 2173 genomes, and found evidence of plas

160 Factors that stabilize these plasmids in bacterial communities contribute to an even

161 quail, based on the in vivo transfection of plasmids in circulating Primordial Germ Cells (PGCs).

162 itated the emergence of MDR via two distinct plasmids in communities consisting of Escherichia coli a

163 and suppressed expression from cotransfected plasmids in MDCK cells.

164 elements were first discovered in bacterial plasmids in the 1980s and have recently been characteriz

165 nes, including a highly effective resistance plasmid, in resident microbial communities.

166 entified an extensive array of AMR genes and plasmids, including an identical multidrug-resistant pla

167 the dependence of chlamydial colonization on plasmid increased over time.

168 Studies of bacterial chromosomes and plasmids indicate that their replication initiator prote

169 Incomplete plasmid information from the PacBio sequencing platform

170 se a community detection algorithm to assign plasmids into cliques, which correlate with plasmid gene

171 pt demonstration by genetically transforming plasmids into Escherichia coli cells, showing transforma

172 Viruses and plasmids (invasive mobile genetic elements (iMGEs)) have

173 The cryptic plasmid is important for chlamydial colonization in the

174 Finally, the list of canonical SEVA plasmids is available in machine-readable SBOL (Syntheti

175 artition," of many low-copy number bacterial plasmids is driven by plasmid-encoded ATPases that are r

176 , including an identical multidrug-resistant plasmid isolated from both S. sonnei and E. coli in the

177 e genes, including blaKPC-2 in an IncFIBpQIL plasmid, KL51 capsule, and yersiniabactin virulence dete

178 tion of PCR cassettes with a Cas12a-encoding plasmid leads to robust endogenous expression of tagged

179 agents for molecules that selectively reduce plasmid levels relative to effects on bacterial growth.

180 The plasmid libraries were delivered to hepatocytes in fumar

181 genomic samples using microfluidic automated plasmid library enrichment.

182 We employed a unique plasmid library expressed in human cells to quantify the

183 rence of the evolutionary history across the plasmid lineages.

184 egions of the nod locus, as well as in other plasmid loci, were associated with differences in CFN.

185 to measure copy number heterogeneity and 2mu plasmid loss in live cells.

186 ur approach to identify compounds that alter plasmid maintenance, confer resensitization to antimicro

187 acin resistance in S. sonnei, in addition to plasmid-mediated azithromycin resistance, is of signific

188 Plasmid-mediated colistin resistance (PMCR) is a global

189 Here, we describe a putative plasmid-mediated mechanism potentially driving decreased

190 estigated host suppression of 2-micron (2mu) plasmids, multicopy nuclear parasites that have co-evolv

191 n clinical settings, summarized as using one plasmid/multiple lineages, multiple plasmids/multiple li

192 sing one plasmid/multiple lineages, multiple plasmids/multiple lineages, and multiple plasmids/one li

193 lon inoculations to reveal the impact of the plasmid on chlamydial colonization in distinct regions o

194 ple plasmids/multiple lineages, and multiple plasmids/one lineage.

195 njection of DNA as a competitor, either in a plasmid or in chromosomal DNA, containing the same bindi

196 Proteins were expressed from transfected plasmids or knocked down with small interfering RNAs in

197 ed protein, along with attB-containing donor plasmids or PCR fragments.

198 an pluripotent stem (PS) cells mainly employ plasmids or ribonucleoprotein complexes.

199 rovides a new alternative to more cumbersome plasmid- or PCR-based protein expression workflows and s

200 rimination of PolI-dependent and independent plasmid origins.

201 CRISPR-targeted plasmids outnumbered their bacteriophage counterparts by

202 Approximately 4500 plasmids overexpressing individual yeast genes were intr

203 obial resistance cassette but carry the IncY plasmid p60006.

204 coded ATPases that are represented by the P1 plasmid ParA protein.

205 mosome (CC), linear chromosome (LC), cryptic plasmid (pAt), and tumor-inducing plasmid (pTi), and gro

206 ed RNase HI protein, RnhP, on the endogenous plasmid pBS32.

207 us faecalis PrgA, encoded by the conjugative plasmid pCF10, is a surface protein that has been implic

208 The cryptic plasmid pCM is critical for chlamydial colonization in t

209 ntly after introduction of SV40 enhancer for plasmid pCMV-ABCA4-SV40 with a CMV promoter.

210 almost exclusively on large, low-copy-number plasmids (pCRE).

211 h of data on prevalence of AMR genotypes and plasmid persistence absent from phenotypic data and, als

212 her, pleiotropic effects resulted in greater plasmid persistence in both novel host-plasmid combinati

213 By selecting for plasmid persistence, the application of antibiotics may

214 green fluorescent protein (GFP) encoded DNA plasmid (pGFP) as a reporter gene.

215 The conjugative Bacillus subtilis plasmid pLS20 uses quorum sensing to determine when to a

216 dleless injection device (Biojector) and DNA plasmid plus gp120 protein plus MF59 adjuvant boost.

217 We have previously shown that plasmid polyplexes can non-virally transfect SVZ NPCs wh

218 bundance in hepatocyte genomic DNA and input plasmid pools identified several thousand miRNA inhibito

219 Further analysis of plasmid population structure allows us to uncover candid

220 At the tissue level, plasmid-positive Chlamydia produced infectious progenies

221 estine but was 530-fold less infectious than plasmid-positive Chlamydia, suggesting that (i) the noni

222 Vaccine Trials Network (HVTN) 111 tested DNA plasmid prime by needle or needleless injection device (

223 nse rates were significantly higher with DNA plasmid prime via Biojector than ALVAC prime (91.4% vers

224 drug-resistant/multidrug-resistant-inducing plasmids, probably facilitated by horizontal transfer fr

225 DNA plasmids promise a pragmatic alternative to viral vector

226 Mobile genetic elements (MGEs), such as plasmids, promote bacterial evolution through horizontal

227 sters; it also underlined the risk of covert plasmid propagation in healthcare settings and revealed

228 a Green fluorescent protein (Gfp)-tagged AR plasmid (pRP4-gfp) within an E. coli host (EcoFJ1) in th

229 he nicking activity of Staphylococcus aureus plasmid pT181 initiator RepC.

230 ), cryptic plasmid (pAt), and tumor-inducing plasmid (pTi), and grows by polar growth from a single g

231 sequencing (4C-seq) using the EBV origin of plasmid replication (oriP) as a "bait" in lymphoblastoid

232 vity including up to complete suppression of plasmid replication and/or plasmid eviction in multiple

233 by inhibiting expression or function of the plasmid replication initiation protein, RepE.

234 , we found kasugamycin and CGS 15943 blocked plasmid replication, respectively, by inhibiting express

235 transposase genes and AMR genes, as well as plasmid replicons, highlights the potential role of hori

236 hat already contain a particular conjugative plasmid resist acquisition of a second copy of said plas

237 Here, we develop a plasmid resource of 690 human RBPs that we subject to lu

238 ng on the Y9 ragi strain, we determined that plasmid restriction is heritable and dominant.

239 oped SCAMPR (Single-Cell Assay for Measuring Plasmid Retention) to measure copy number heterogeneity

240 This role depends on the plasmid's ability to persist in a population.

241 be used to detect contaminating sequences in plasmid samples.

242 t contexts - from improved reconstruction of plasmid sequences and refined analysis of metagenomic da

243 ce pipeline for assembly and verification of plasmid sequences from Illumina reads.

244 small molecules that efficiently evict pCRE plasmids should restore much-needed treatment options.

245 few species of bacteria and their phage and plasmids show that CRISPR-Cas systems can play this role

246 Neither gene expressed separately from plasmids showed activity, but the concurrent expression

247 Following an intragastric inoculation, the plasmid significantly improved chlamydial colonization.

248 cellular bacteria, have coevolved with their plasmids since their last common ancestor.

249 mu plasmids and reproducibly inhibit mitotic plasmid stability.

250 mosomes and plasmids with roles ranging from plasmid stabilization to biofilm formation and persisten

251 Standard curves based on tenfold diluted plasmid standard exhibited high specificity and sensitiv

252 f a vaccine platform based on a unique three-plasmid system to efficiently generate recombinant MVA v

253 if the same interactions were observed for F-plasmid T4SS proteins and when one interaction partner w

254 These isolates harbored a large plasmid that carries a novel antibiotic resistance integ

255 ne editing; some cells were transfected with plasmids that express FAF1 missense variants.

256 acity when the target genes are located on a plasmid, the CapsidCas13a(s) exhibit strong bacterial ki

257 ome and frequently carrying numerous cryptic plasmids - their genomes are often pockmarked with inser

258 gration of both viral DNA ends into a target plasmid then proceeded in a cell extract-dependent react

259 Whilst associated with the maintenance of plasmids, they also act in bacterial immunity and antibi

260 The transfer of this plasmid to a vancomycin-susceptible C difficile isolate

261 nhanced green fluorescent protein-expressing plasmid to cells at a scalable throughput of 200,000 cel

262 Agrobacteria require an oncogenic Ti or Ri plasmid to transfer genes into plants and cause disease.

263 e plasmid vectors, but also new links of the plasmids to advanced bioinformatic tools.

264 adopted in this work to help facilitate DNA plasmids to cross both cell plasma membrane and nuclear

265 coustofluidic sonoporation method to deliver plasmids to immortalized and primary human cell types, b

266 DNA makes these a useful tool for delivering plasmids to study proteins of interest in a variety of c

267 ion mediated by different types of phage and plasmids to the evolution and maintenance of CRISPR-Cas

268 Using both luciferase and GFP plasmid transfections, we show that the time delay betwe

269 ly found that antimicrobial usage may impact plasmid transfer between commensal E. coli and S. sonnei

270 Plasmid transfer frequencies were also higher under anae

271 s in all 2173 genomes, and found evidence of plasmid transfer independent from bacterial transmission

272 We identified physical constraints on plasmid transfer that can explain why our focal strain f

273 daptive immunity against virus infection and plasmid transformation.

274 al patterns that highlight the importance of plasmid transmission in pathogen diversification as well

275 were phylogenetically dissimilar, suggesting plasmid transmission.

276 can be extensive and is driven by different plasmid types, with the IncX type being the most activel

277 rk partitioning based on a pruned network of plasmid unitigs.

278 Confocal microscopy of quantum dot-labeled plasmid uptake in vivo reveals association between our p

279 re user-friendly web interface and many more plasmid vectors, but also new links of the plasmids to a

280 In order to facilitate plasmid verification to improve the quality and reproduc

281 We evaluated DNA plasmid versus canarypox virus (ALVAC) primes in 2 rando

282 cus faecalis, conjugation of a Cas9-targeted plasmid was enhanced by anti-CRISPRs derived from Entero

283 A novel GES-5-encoding plasmid was present in K. oxytoca, Escherichia coli, and

284 The synthetic plasmid was then introduced into an E. coli K12 tolC hos

285 ent-specific (+)RNAs [(+)ssRNAs], a chimeric plasmid was transfected, from which the capping enzyme N

286 otein fusions either from endogenous loci or plasmids were directly compared in functional assays.

287 efficiencies were more stable than when the plasmids were incubated in unfiltered and unheated aged

288 ikelihood that a host will already contain a plasmid when it acquires another through conjugation.

289 imarily via the single epidemic pOXA-48-like plasmid, which emerged recently in clinical settings and

290 We show that these plasmids, which include pKpQIL-like and IncX3 plasmids,

291 to lytic and temperate phage and conjugative plasmids will select for and maintain CRISPR-Cas systems

292 Based on the co-delivery of an improved Cas9 plasmid with multiple sgRNA plasmids and an efficient sc

293 In this study, we modified the ABCA4 plasmid with simian virus 40 enhancer (SV40, pRHO-ABCA4-

294 rticles containing nonintegrating expression plasmids with Foxm1 or Foxf1 cDNAs were injected intrave

295 d via transient associations of many diverse plasmids with numerous lineages.

296 are found in many bacterial chromosomes and plasmids with roles ranging from plasmid stabilization t

297 can be costly, and long-term association of plasmids with their hosts is poorly understood.

298 re than 94% of gonococci possess the cryptic plasmid, with its absence correlated with the presence o

299 aptation was mostly limited to the symbiosis plasmids, with mutations in putative signaling genes.

300 8/512) yet have been mobilized among diverse plasmids within this lineage.