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1 l population had only a minor effect on anti-plasmodial activity.
2                             For this reason, plasmodial ADA accepts a wider range of substrates, as i
3 highlight a drastic conformational change in plasmodial ADA upon substrate binding that has not been
4                      PYR is known to inhibit plasmodial and human dihydrofolate reductase (DHFR).
5 e comparison of inhibitor complexes with the plasmodial and human enzymes.
6 is natural difference in specificity between plasmodial and mammalian ADA has not been well understoo
7 MP potency and selectivity toward bacterial, plasmodial, and cancerous cells while enabling the targe
8 , T cells from infected mice stimulated with plasmodial antigen triggered 5-10-fold increases in p24
9 he identified gene, pypag-1, encoded a novel plasmodial antigen.
10                    Unlike many characterized plasmodial antigens, blocks of tandemly repeated amino a
11 e need a deeper understanding of fundamental plasmodial bioregulatory mechanisms to successfully subv
12                      The characterization of plasmodial CDKs has identified them as a leading antimal
13 Physarum polycephalum, when transplanted, by plasmodial coalescence, into an S-phase plasmodium, fail
14  the vector Anopheles, thus perpetuating the plasmodial cycle.
15                              FP2 and related plasmodial cysteine proteases have an unusual 14-aa moti
16  for folding of falcipain-2 and four related plasmodial cysteine proteases was inclusion of a 14-15-r
17 es represent the first crystal structures of plasmodial cysteine proteases with small molecule inhibi
18 ned in silico against the homology models of plasmodial cysteine proteases, falcipain-2, and falcipai
19 insights into the intricacies characterising Plasmodial developmental biology.
20 DSM265 is a novel antimalarial that inhibits plasmodial dihydroorotate dehydrogenase, an enzyme essen
21             We have previously reported that plasmodial DNA is the primary driver of systemic inflamm
22 afted with primate tissue make two important plasmodial dormancy-related questions researchable.
23                        Secretion of the anti-plasmodial effector peptides inside the mosquito midguts
24 was genetically modified to secrete two anti-plasmodial effector peptides, MP2 (midgut peptide 2) and
25                                          The plasmodial enzyme adenosine deaminase (ADA) plays a cent
26                                          The plasmodial enzyme dipeptidyl aminopeptidase 1 (DPAP1) wa
27                                              Plasmodial enzymes for the synthesis of PABA via the shi
28 s, we propose a specific role for one of the plasmodial enzymes, aminopeptidase P, in the catabolism
29                            This channel, the plasmodial erythrocyte surface anion channel (PESAC), li
30 id foundation for the ongoing elucidation of plasmodial gene expression.
31  strategy may be widely applicable to modify plasmodial genes and perform structure-function analyses
32 ort the relative susceptibility of human and plasmodial GRs to a series of tricyclic inhibitors as we
33 yte modification by the parasite may involve plasmodial heat shock proteins and be vastly more comple
34 rties of Hs-18Pf-SAHH, the human enzyme with plasmodial helix 18, and Tc-18Hs-SAHH, the trypanosomal
35 n is seen as an additional substrate only in plasmodial homogenates.
36 ms in the pfmdr1 gene, the gene encoding the plasmodial homologue of mammalian multidrug resistance t
37 m-infected RBCs appeared to be suppressed by plasmodial infection, as both increased after antimalari
38                                          Ape plasmodial infections were highly prevalent, widely dist
39  treatments are available to prevent or cure plasmodial infections, but genetic mutations in the caus
40                                    Essential plasmodial kinases PfGSK3 and PfPK6 are considered novel
41    Recently, we discovered and validated the plasmodial l-lactate transporter, PfFNT, as a novel anti
42 consistent with recent observations that the plasmodial MAPKs are not true orthologues of the ERK1/2,
43 f the mode of activation and function of the plasmodial MAPKs.
44                  Invasion of erythrocytes by Plasmodial merozoites is a composite process involving t
45 , epoxyazadiradione inhibited both huMIF and plasmodial MIF, thus bearing an immense therapeutic pote
46 is not directly exchanged for protons by the plasmodial Na+/H+ exchanger.
47 insight into this process, we have studied a plasmodial ortholog of the lysosomal exopeptidase cathep
48                            Dependence of the plasmodial parasites on selenium suggests possible strat
49 fic inhibitors that could potentially target plasmodial PI4KIIIbeta to combat malaria.
50 alytic domain with extensions from six other plasmodial proteases folded normally and had kinetic par
51   Recent advances in the characterization of plasmodial proteases should facilitate the analysis of t
52                                  A number of plasmodial proteases that appear to be responsible for k
53 nose) and FP2(arm) are found only in related plasmodial proteases, suggesting that they confer malari
54 on of the domains of falcipain-2 and related plasmodial proteases.
55 re we report the characterization of a novel plasmodial protein kinase, PfPK7, whose top scores in bl
56 rotein kinase family, similar to a few other plasmodial protein kinases.
57       Given the involvement of sugar binding plasmodial proteins in host invasion, we set out to iden
58                                Several vital plasmodial proteins were efficiently destroyed by granzy
59 Because they occur in almost all families of plasmodial proteins, the occurrence of LCRs cannot be as
60 the parasite without inhibiting secretion of plasmodial proteins.
61           Sequence alignment showed that the plasmodial sequence has 47% identity with human IRP1.
62 stent with the differences between human and plasmodial sequences in the Q2 pocket receiving this gro
63 ns to bacterial flow through porous media or plasmodial shuttle streaming in slime molds.
64                                              Plasmodial slime molds grow as networks and use flexible
65      Furthermore, if spore stages as well as plasmodial stages were detected in tissue, stool specime
66                 Recent studies implicate the plasmodial surface anion channel (PSAC) and a role in pa
67 ty to ions and nutrients, as mediated by the plasmodial surface anion channel (PSAC) and recently lin
68                                          The plasmodial surface anion channel (PSAC) increases erythr
69                                          The plasmodial surface anion channel (PSAC) is an unusual io
70                                          The plasmodial surface anion channel (PSAC) is an unusual sm
71                                          The plasmodial surface anion channel (PSAC) may mediate thes
72                                The conserved plasmodial surface anion channel (PSAC) mediates nutrien
73                                          The plasmodial surface anion channel (PSAC) mediates this tr
74                                          The plasmodial surface anion channel (PSAC), an unusual volt
75                                          The plasmodial surface anion channel (PSAC), recently identi
76 n unusual voltage-dependent ion channel, the plasmodial surface anion channel (PSAC), which may accou
77 ll patch-clamp indicate direct action on the plasmodial surface anion channel, a channel linked to pa
78 echanism involving genes responsible for the plasmodial surface anion channel, a nutrient channel tha
79 pathways, essential biological processes for plasmodial survival.
80                                              Plasmodial transglutaminase of Physarum polycephalum was
81         The internalized host proteins and a plasmodial transmembrane resident parasitophorous vacuol
82                             Herein, the anti-plasmodial transmission blocking activity of a recombina
83 sident proteins are detected as rafts in the plasmodial vacuole, (2) a voltage-gated channel in the i
84                                    This is a plasmodial, vegetative stage of acellular slime mould.