ライフサイエンスコーパス: player

1 sponse, where the complement system is a key player.

2 ity, protein stability is arising as a major player.

3 ing ETC generated H(2)O(2) is not a critical player.

4 with the stress hormone system as a central player.

5 within this the ribosome particle is the key player.

6 ard outcomes and predictions about the other player.

7 with CTE diagnoses in both older and younger players.

8 ty cannot explain faster VRT in elite sports players.

9 p = 0.043 FDR-corrected) than beginner chess players.

10 Despite being a postmortem diagnosis, 108 players (2.8%) self-reported clinician-diagnosed CTE.

11 emales, 28 males), professional rugby-league players (21 males), and non-sporting controls (20 female

12 our approach to a new 2 x 2 game, where one player, a leader, ensures via inspection and punishment

13 via inspection and punishment that the other player, a subordinate, produces collective good.

14 A survey of 3,913 former ASF players aged 24 to 89 was conducted for those who respon

15 Sixty-six retired professional ASF players aged 29 to 75 years completed a health and welln

16 e primary cause was 1.7% among former soccer players and 0.5% among controls (subhazard ratio [the ha

17 ectivity parameters of 18 professional chess players and 20 beginner chess players were evaluated app

18 nned 42 adult male amateur American football players and a control group comprising 27 athletes pract

19 e in rate of death by suicide between soccer players and controls.

20 for mental health disorders between outfield players and goalkeepers.

21 current understanding of the major molecular players and known pathways that are involved in control

22 spite major advances in our understanding of players and mechanisms involved in peroxisome biogenesis

23 omeostasis relies on an intricate network of players and mechanisms that assist in the different form

24 (CHD), but our understanding of the genetic players and networks involved in CHD pathogenesis is lim

25 matic head trauma in former professional ASF players and other contact sport athletes.

26 To decipher involved immunological players and pathways, human skin biopsies were taken at

27 poral response profile of the major cellular players and soluble factors involved in priming the BM a

28 that these elements may be key evolutionary players and that the full scope of their roles is only b

29 However, the molecular players and the mechanisms regulating the gene-specific

30 actorial, and identifying reliable molecular players and/or biomarkers has proven difficult.

31 he human Vdelta1 population and discuss what players are involved in transducing phosphoantigen-media

32 wn superior performance in action video game players (AVGPs) compared to non-players (<= 5 h/week acr

33 cluded (rugby, American football, ice hockey players, boxers and marital art fighters).

34 heory in oncology: we can treat not only the player, but also the game.

35 ort in a subset of amateur American football players, but not in sex- and age-matched controls.

36 ing barrier dysfunction in American football players', by Veksler et al. (doi:10.1093/brain/awaa140).

37 our findings reconcile how common molecular players can participate in the two opposing functions of

38 We show that the players can tune their playing period and delete connect

39 These players come alive via their own words, as complex indiv

40 In a virtual ecosystem, players compete for habitats and resources, unintentiona

41 r findings identify FHR-4 as a key molecular player contributing to complement dysregulation in AMD.

42 But what if players could perceive each other's emotional expression

43 rine breast cancer cells to identify the key players establishing epithelial-mesenchymal cell plastic

44 Professional chess players exhibited an increased dynamic fluidity, express

45 Furthermore, professional chess players exhibited an increased dynamic range, with incre

46 of genre characteristics; greater freedom of player experience) calls for a paradigm shift relative t

47 rentiation transactivates SPINK1, a critical-player for maintenance of NE-phenotype.

48 Our study defines UGDH as a key player for the production of extracellular matrix compon

49 by we hypothesize that phytohormones are key players for BS induction and suppress the expression of

50 Molecular players found only in vertebrates allow the modification

51 characterization of circ-MDM2 identify a new player from the MDM2 locus that suppresses p53 levels an

52 nce sample of 266 deceased American football players from the Veterans Affairs-Boston University-Conc

53 The molecular players governing microtubule (MT) reorganization during

54 The molecular players governing this transition remain poorly defined.

55 nd with years of football play in the former-player group.

56 game categories) and multi-genre video game players (> 5 h/week across game categories).

57 traumatic brain injury in American football players has garnered increasing public attention followi

58 Some former professional football players have been clinically diagnosed with CTE, a postm

59 s has been broadly delineated, key molecular players have been identified, and the impact of this sys

60 Therefore, intercellular communication players have emerged as attractive powerful therapeutic

61 identified the I(h) channel as an important player in a subset of clock neurons of the fruit fly.

62 Hippo pathway, but also reveals STXBP4 as a player in actin cytoskeleton tension-mediated Hippo path

63 that profiles tumors on the basis of the key player in adaptive antitumor response, CD8+ cells, and e

64 ntral nucleus of the amygdala (CeA) is a key player in alcohol-dependence associated behaviors.

65 The identification of dectin-1 as a key player in allergy to tropomyosins and the formyl peptide

66 Since LOX is an established player in cancer cell migration, our results imply that

67 g mitochondrial respiration as well as a key player in carbon-nitrogen interactions.

68 onclusion, our work establishes TG2 as a key player in controlling glucose-derived metabolic pathways

69 sulfide (H(2)S) is emerging as an important player in cytoprotection against these stressors, which

70 a implicates chronic inflammation as a major player in depression pathogenesis.

71 REV1 is known to be a key player in DNA repair pathway and to interact with HSP90.

72 blasts pointed at mechanosensor YAP as a key player in ECM remodeling in the diseased heart via trans

73 Indeed, a major emerging player in ER turnover is ER-phagy, the degradation of ER

74 dings identify the inflammasome as a crucial player in establishing a properly formed CNS through its

75 Here we investigated the roles of Rab27a, a player in exosome release, and TRAF3IP2, an inflammatory

76 lear pore complex (NPC) has emerged as a key player in genome regulation and cellular homeostasis.

77 TMEJ regulation, highlighting ZEB1 as a key player in genome stability during cancer progression via

78 the cell, remains unexplored as a potential player in global oxygen dynamics.

79 follicular helper T cell (T(FH)), a critical player in humoral immunity, is associated with disease s

80 on is the transcript encoding PKR, a crucial player in immune and viral response.

81 undant transition metal and is already a key player in important industrial processes (e.g. polyethyl

82 e data indicate that 12/15-LOX is a critical player in induction of the earliest aspects of the innat

83 Bacterial chemotactic ability is a major player in infiltration, and plant stomatal defense in cl

84 ing protein 43 (TDP-43) has emerged as a key player in many neurodegenerative pathologies, including

85 T OXIDASE HOMOLOG D (RBOHD) protein as a key player in mediating rapid systemic ROS responses.

86 the transcription factor Sox10 as a crucial player in melanoma, yet the underlying molecular mechani

87 hlight the significance of the EC as a major player in memory processing, along with other associated

88 ent that binds to and stabilizes Bub3, a key player in mitotic spindle assembly checkpoint signaling.

89 MutL complexes found in mammals and a minor player in MMR.

90 cordingly, we infer that EAAT5 may well be a player in modulating neuronal function in the human brai

91 It is a key player in multiple human maladies including diabetes, ca

92 ify phosphatase orphan 1 (Phospho1) as a new player in myogenesis.

93 Although a critical player in naive T cell homeostasis, the ability of VISTA

94 romptly increased by protein kinase A, a key player in neuromodulation.

95 , these findings identify SULT4A1 as a novel player in neuron development and function by modulating

96 These data point to the VP as a critical player in obesity and suggest that hyperpolarized membra

97 Alpha-synuclein (aSyn) is a central player in Parkinson's disease (PD) but the precise molec

98 alpha-synuclein (aSyn) is a major player in Parkinson's disease and a group of other disor

99 y an exuberant innate immune response as key player in pathogenesis, in which STAT2 signaling plays a

100 gh our study, DOT1L is emerging as a central player in physiology of CD8(+) T cells, acting as a barr

101 Gln is a key player in plant metabolism.

102 in-mediated cell-matrix interaction is a key player in pluripotency exit regulation.

103 r results identify the Src/YAP axis as a key player in promoting the proliferation and migration of E

104 DNA-dependent metalloprotease, is a central player in proteolytic cleavage of DPCs.

105 er vaccine candidate to recognition as a key player in regulating critical pathways controlling the c

106 tactin, in endothelial cells is an important player in regulating the interaction of immune cells wit

107 The plant NADPH oxidase RBOHD is a primary player in ROS production during innate immunity.

108 sterol O-acyltransferase 1 (SOAT1) as a key player in sustaining the mevalonate pathway by convertin

109 ogether, our findings pinpoint NAV1 as a key player in the actin-MT crosstalk that promotes MT persis

110 I argue that fluency is a key player in the attribution of familiarity regardless of t

111 hosphatase 1), has been revealed to be a key player in the balance of pyrimidine nucleotide concentra

112 Tau tubulin kinase 2 (TTBK2) is a key player in the cilium assembly pathway, controlling the f

113 lysosomal Ca2+ channel Trpml as an essential player in the coupling of cell locomotion and phagocytos

114 VDAC1 is a crucial player in the cross talk between the mitochondria and th

115 antagonist (IL-1Ra) has emerged as a pivotal player in the defense against periodontitis.

116 ultiple levels, C1QBP is, thus, an important player in the DNA damage response.

117 cruiter, we hypothesized that SETD6 is a key player in the epigenetic control of long-term memory.

118 we argue that HGT is a small but significant player in the evolution of microbial eukaryotes and prov

119 gs demonstrate that DNASE1L3 is an important player in the fragmentation of plasma DNA, which appears

120 here we show that the cofactor NADH is a key player in the GDH regulation process. Our structural ana

121 Nitrogenase is a key player in the global nitrogen cycle, as it catalyzes the

122 in superfamily proteins and represents a key player in the innate immune response.

123 Driver mutations in the BRAF gene, a key player in the MAPK pathway, are described in multiple tu

124 e data presented here identify Bmh1 as a key player in the mechanism of licensing of chromosome compa

125 ts that Toll-like receptor 4 (TLR4) is a key player in the mechanisms associated with hypertension.

126 Whether liver fibrosis might be a relevant player in the natural history of COVID-19 is currently u

127 factor (MIF) has been recognized as a major player in the pathogenesis of atherosclerosis.

128 his metal ion is believed to be an important player in the pathogenesis of this disease.

129 in-derived neurotrophic factor (BDNF), a key player in the pathophysiology of major depression and th

130 ents of the FGF signaling pathway, a central player in the process of neural induction in amniotes.

131 demonstrate that neuroinflammation is a key player in the progression of Alzheimer's disease (AD).

132 ella vaginalis has been considered a pivotal player in the progression of bacterial vaginosis (BV), a

133 mark of the pancreatic beta-cell, a critical player in the regulation of blood glucose concentration.

134 Thus, we reveal a key player in the regulation of HR and TLS with significant

135 cation in humans and functions as a critical player in the regulation of tissue and cell-specific gen

136 vation, suggesting that TrkA is an important player in the signaling pathway activated by eotaxin-1 d

137 RNA deadenylase complex, CNOT, is a central player in the vE-MAP and show that knockout of CNOT1, 10

138 as become clear that sphingolipids are a key player in these responses.

139 A key player in this adaptation is the circadian clock.

140 conserved subunits, has emerged as a central player in this process.

141 and that the protein Spata18 is an important player in this process.

142 eling complex has also emerged as a critical player in tumor progression, leading to the identificati

143 PVAT function supports PVAT as an essential player in vascular health.

144 thymus and have been identified as critical players in a broad range of infections, antitumor survei

145 N-glycans are important players in a variety of pathologies including different

146 ength regulators and as such represent novel players in actin-dependent centrosome to basal body conv

147 ertible fluorescent proteins (PCFPs) are key players in advanced microscopy schemes such as photoacti

148 tive and innate immune responses, as well as players in an important role in the pathogenesis of a va

149 an emphasis on CD8(+) T cells, which are key players in anti-tumor immunity.

150 histone deacetylases (HDACs) and many known players in ASD etiology such as transducin beta-like 1 X

151 nal interplays between NCORs and other known players in ASD etiology.

152 Neutrophils are important players in bacterial clearance and are recruited to the

153 Reactive oxygen species are key players in biotic and abiotic stress responses, but ther

154 Key players in both metabolism and transcriptional regulatio

155 d function and in activating some of the key players in cell division.

156 tion of fatty acid metabolism, thus critical players in cell envelope assembly.

157 onnection with their receptors are important players in cell-to-cell communications in plants.

158 reas microglia are recognized as fundamental players in central nervous system (CNS) development and

159 macrophages of the brain parenchyma, are key players in central nervous system (CNS) development, hom

160 LncRNAs have been shown to be direct players in chromatin regulation, but little is known abo

161 we study the synchronization between violin players in complex networks with full and accurate contr

162 uitous two-component systems that are global players in control and adjustment of microbial lifestyle

163 erodimers, and not homodimers, are the major players in determining the amplitude of MAPK signaling i

164 rentiation of specialized cell types are key players in development and tissue regeneration.

165 rticular, metabolites are emerging as active players in driving immunosuppression.

166 most major eukaryotic lineages-as important players in ecosystems across Earth's biomes.

167 (ER) and endosomes have emerged as important players in endosomal protein sorting, dynamics and motil

168 se to necrotic cells and may thus be crucial players in exacerbating autoimmunity targeting the heart

169 encing technologies have emerged as powerful players in genomics.

170 Glutamate transporters are essential players in glutamatergic neurotransmission in the brain,

171 inant genetic modifiers known to be relevant players in human NAFLD and which may determine key compo

172 Neutrophils are pivotal players in immune defence which includes a process of re

173 Whether these cells remain key players in later stages of disease is unknown.

174 identify CLN6 and the EGRESS complex as key players in lysosome biogenesis and shed light on the mol

175 g the last decade have shown they are active players in many aspects of CNS physiology and function b

176 Glycine receptors (GlyRs) are key players in mediating fast inhibitory neurotransmission a

177 le in graft rejection, but can also be major players in mediating transplantation tolerance.

178 roles for CDR1as and expose circRNAs as key players in metastasis.

179 , maintenance of the vasculature and are key players in microvascular pathology.

180 aterian mitochondria-encoded tRNA genes, key players in mitochondrial activity, have accumulated muta

181 rstanding of phagocytic glia as double-edged players in neurodegeneration-by clearing neurotoxic prot

182 ived microglia-like cells, which are central players in neurodegeneration.

183 We specifically focus on microglia as major players in neuroinflammation and discuss the spatial and

184 e and suggest the existence of new potential players in OM biogenesis.

185 Hepatic tissue macrophages are key players in orchestrating liver inflammation, and ER stre

186 Scaffold proteins are central players in regulating the spatial-temporal organization

187 lligence (AI) system defeated the best human players in StarCraft II, a popular real-time strategy ga

188 ence that astrocytes are active and integral players in synaptic communication, and that neuron-astro

189 RNAs as post-transcriptional, regulatory key players in the 1990s, a total number of $2656$ mature mi

190 essing tumor-associated myeloid cells as key players in the accumulation of LMW-HA in the tumor micro

191 nate lymphocytes that are considered central players in the antiviral response.

192 Many central players in the book, including Sydney Brenner, Seymour B

193 re recently been used to identify additional players in the cAMP-signaling cascade.

194 us-end tracking proteins (+TIPs) are central players in the coordination between the MT and actin cyt

195 with elevated IL-6 and IP-10 levels, two key players in the cytokine storm.

196 They are critical players in the development, normal function, and decline

197 microRNAs are suggested to be important players in the disease pathogenesis and the experimental

198 Bacteriophages (phages) are critical players in the dynamics and function of microbial commun

199 identify gammadelta T cells as potential key players in the early host response to S. aureus during b

200 ASCIATED (encoding SlCLV3) loci, two central players in the evolution of fruit size in the domesticat

201 nsition (EMT) have recently emerged as novel players in the field of leukemia biology.

202 Brown algae are important players in the global carbon cycle by fixing carbon diox

203 g recognized that NOD1 and NOD2 are critical players in the host immune response, primarily by their

204 ve previously shown that centrosomes are key players in the initiation of subcellular lumen formation

205 l intracellular pathogens as well as central players in the local and systemic metabolic adaptation t

206 r-associated fibroblasts (CAF) are prominent players in the microenvironment of breast cancer.

207 suggest that these cells are multifunctional players in the midbrain reward circuitry.

208 t almost indisputable that peptides were key players in the origin of life.

209 s including low-grade inflammation are major players in the pathogenesis of cardiovascular disease (C

210 lved in homeostasis of the brain and are key players in the pathogenesis of multiple sclerosis (MS).

211 ges in mitochondrial gene expression are key players in the prefrontal adaptations observed in indivi

212 Hepatic stellate cells are key players in the progression of HCC, as they create a fibr

213 e results demonstrate that PNNs are critical players in the regulation of cerebellar circuitry and fu

214 , TCP, SRS and DOF families may be the major players in the regulation of gene expression in the glan

215 those colonizing the phycosphere, are major players in the remineralization of algal-derived carbon.

216 RNA modifications are emerging as critical players in the spatiotemporal regulation of gene express

217 ubiquitous DNA-binding protein CLAMP are key players in the specificity of X chromosome binding.

218 1 and shows that both proteins are important players in the SSA and BIR pathways of DSB repair.

219 creatic stellate cells (PSCs), the two major players in the TME, we can effectively manipulate the ph

220 s) and gammadelta T cells, are promising new players in the treatment and prevention of infectious di

221 s system, are now considered to be important players in the tumor microenvironment.

222 mately activated over 2,800 genes, including players in the unfolded protein response and proinflamma

223 Key players in the UPS are E3 ubiquitin ligases, responsible

224 sal distances, plants are not purely passive players in these processes.

225 thorax Group (TrxG) proteins are the central players in this cell type-specific chromatin organizatio

226 ght in clock entrainment and known molecular players in this process.

227 Given that lncRNAs are emerging as key players in tissue physiology and disease progression, in

228 e RNA-DNA hybrid sequences that are emerging players in various biological processes, occurring in bo

229 ecific biomarkers as well as novel candidate players in virus-host interactions.

230 athologies by upregulating these two pivotal players, in addition to escalating delta-secretase activ

231 n together, we identified CBFbeta as the key player involved in D/N interference by Vif.IMPORTANCE Of

232 ring opportunities to discover new molecular players involved in auxin responses.

233 many eukaryotes differ in the composition of players involved in centromere maintenance, highlighting

234 tem (CNS), and further identify the cellular players involved in mediating acute inflammatory signali

235 Among currently known molecular players involved in TGN transport, three different adapt

236 emain, BETs have emerged as novel epigenetic players involved in the execution of coordinated transcr

237 sion yeast have revealed different molecular players involved in two meiotic cell divisions, meiosis

238 e from the virus itself, important molecular players involved in virus entry include the tetraspanin

239 The molecular players involved include phototropin photoreceptors, pla

240 A key player is the viral protein Zta (BZLF1, ZEBRA, or Z).

241 re complex, and our understanding of all the players is far from complete.

242 evelopment, thus suggesting FABP4 as a novel player linking obesity and breast cancer risk.

243 n video game players (AVGPs) compared to non-players (<= 5 h/week across game categories) and multi-g

244 Healthcare industry players make payments to medical providers for non-resea

245 itive impairment, clinicians treating former players may be inclined to suggest CTE without a thoroug

246 alignancies, characterizing the pathways and players mediating its action is fundamental.

247 Some of the same players modulate symplastic transport to seasonally regu

248 rediction, respectively, suggesting that top players' moves are partially stereotyped.

249 late acute) following concussion in football players (n = 106), matched uninjured football players (n

250 layers (n = 106), matched uninjured football players (n = 84), and non-contact-sport athletes (n = 50

251 For a cohort of former professional soccer players (n=7676) with known high neurodegenerative morta

252 MET (HGF/MET) axis is emerging as a critical player not only in the tumor itself but also in the immu

253 ng drugs can reasonably be seen as potential players not only for relapse prevention but also as cand

254 The proteasome is a key player of regulated protein degradation in all kingdoms

255 Ion transporters are key players of cellular processes.

256 B lymphocytes are important players of the adaptive immune system.

257 ed is recruited independently from the other players of the anterior-posterior specification network

258 n extravascular compartments and are central players of the innate immune system, contributing to fir

259 r discuss how innate immune responses can be players of the organismal proteostasis network and discu

260 y repurposing TCR, CD25 and PD1, three major players of the T cell activation pathway.

261 y to express EPO, and we discovered here new players of this transcription, distinct from the classic

262 le to perceptual information about the other player or motor contingencies.

263 factor, MMP14 is also likely to be an early player, owing to its role in EMT.

264 WDR90 is an evolutionary conserved molecular player participating in centriole architecture integrity

265 ve disease is high among professional soccer players, potentially associated with repeated head impac

266 athetic neurons, we investigate the roles of players previously implicated in the progression of Wall

267 ingle coalition without enforcement and with players pursuing their self-interest without knowledge o

268 portant roles, different types and molecular players regulating developmental cell death, and discuss

269 s, but the specific mechanisms and molecular players remain elusive.

270 , including payoffs, intentions of the other player, reward outcomes and predictions about the other

271 However, the molecular players serving efferent control of LL hair cell (HC) ac

272 shepherd' effect, which - if anticipated by players - should strategically deter free-riding under o

273 ulation controls, former professional soccer players showed lower risk of hospital admission for anxi

274 mselves as well as individual differences in player style determining the final outcome.

275 ession of colorectal cancer along with major players such as intestinal microbiotic dysbiosis and chr

276 ivesicular endosomal machinery and the novel player TFG have important roles in Wnt signaling.

277 an flortaucipir SUVR was higher among former players than among controls in three regions of the brai

278 get miRNAs, miR-30c-2*, and miR-497 as major players that can suppress progression and metastasis of

279 se, and thus it is imperative that molecular players that maintain neuronal coordination of energy ho

280 together, our results identify key molecular players that regulate ADGRB1 gene expression in MB, demo

281 However, little is known about the molecular players that regulate mitochondria in neural circuits re

282 stitial fluid, unraveling novel inflammatory players that shape the cellular and proteomic microenvir

283 Here, we classify the key players that transform primary transcripts into mature m

284 Defining the metabolic needs of the three players, the mechanisms through which they acquire nutri

285 nt proteins C1q and C3 are recognized as key players, the neuronal molecular components that specify

286 cephalopathy (CTE) have been reported in ASF players, there are currently no established premortem di

287 Among soccer players, there was no significant difference in risk of

288 Thus, beta-catenin likely represents another player through which BCR signaling impacts on MCL cell s

289 ield by identifying new important biological players to be further characterized by in vitro and in v

290 velope-associated proteins, and adds two new players to the increasingly complex system of guard cell

291 hosphoinositide 3-kinase (PI3K) as a central player transducing ACM-mediated neuroprotection.

292 The percentage of players under age 60 years reporting a CTE diagnosis was

293 However, the identities of the molecular players underlying ACh-mediated inhibition in the LL rem

294 Identifying the molecular players underlying neuropathic pain induced structural a

295 essional chess players and 20 beginner chess players were evaluated applying spatial independent comp

296 ouble-strand breaks, including the molecular players which mediate the degradation of linear mtDNA fr

297 ermeability persisted for months, as seen in players who were scanned both on- and off-season.

298 g a population of former professional soccer players with known high neurodegenerative disease mortal

299 shopping, while FMCGs purchased through pure players with parcel delivery often have higher GHG footp

300 e novel role of kisspeptin neurons as active players within the neuronal circuits that govern energy