ライフサイエンスコーパス: plexiform

1 s a simple, two layered cortex with an outer plexiform and inner cell zone (Layers 1 and 2, respectiv

2 tinography amplitudes, and thinned the outer plexiform and inner nuclear layers of both WT and hWtEPO

3 ial hypertension (PAH) that recapitulate the plexiform and obliterative arteriopathy seen in PAH pati

4 aration of neurosensory retina between outer plexiform and outer nuclear layers.

5 dian manner, in interneurons in the external plexiform and periglomerular layers, whereas VPAC2R is e

6 hereas STIM2 is mainly confined to the outer plexiform and RGC layers.

7 f photoreceptors with hyper-reflective outer plexiform and RPE/Bruch's membrane (BrM) layers within l

8 l layers (nerve fiber, ganglion cells, inner plexiform, and inner nuclear layers) of eyes with previo

9 ipheral displacement of ganglion cell, inner plexiform, and inner nuclear layers.

10 he retinal nerve fiber, ganglion cell, inner plexiform, and outer plexiform layers and increased thic

11 vision loss and bilateral subhyaloid, outer plexiform, and subretinal hemorrhages after 2 minutes of

12 ciently reaching the inner nuclear and outer plexiform, and to a lesser extent the outer nuclear laye

13 Therefore, this review will focus on plexiform arteriopathy in experimental animal models of

14 oliferation and selection of a proliferative/plexiform EC phenotype.

15 for classifying NoDR vs NPDR; (b) the outer plexiform, inner nuclear and ganglion cell layers are th

16 inner plexiform layer (GCL+IPL), RNFL, outer plexiform/inner nuclear layers (OPL+INL), and outer nucl

17 0.25 mum/y) and the ganglion cell (GC)/inner plexiform layer (0.29 mum/y) on optical coherence tomogr

18 including both glomerular layer and external plexiform layer (EPL) computations and incorporating bot

19 We found that, whereas external plexiform layer (EPL) interneurons show broadly distribu

20 , including granule cells (GCs) and external plexiform layer (EPL) interneurons.

21 odendritic synaptic circuits in the external plexiform layer (EPL).

22 ateral dendrites in the superficial external plexiform layer (EPL); (2) axodendritic synapses onto GC

23 f the perifoveal retinal ganglion cell-inner plexiform layer (GC-IPL) and the peripapillary retinal n

24 e fiber layer (RNFL) and ganglion cell-inner plexiform layer (GC-IPL) of patients with DOA were evalu

25 as to study the macular ganglion cell- inner plexiform layer (GC-IPL) thickness in healthy 6.5 year-

26 thickness, rim area, and ganglion cell-inner plexiform layer (GC-IPL) thickness measurements were eva

27 thickness (CST), macular ganglion cell-inner plexiform layer (GC-IPL) thickness, and peripapillary re

28 Rates of ganglion cell + inner plexiform layer (GCIP) and whole-brain (r = 0.45; p < 0.

29 AAs (p = 0.047), whereas ganglion cell/inner plexiform layer (GCIP) thickness did not differ by race.

30 nd that of the ganglion cell layer and inner plexiform layer (GCIP, -11.3 mum), whereas the thickness

31 The common ganglion cell and inner plexiform layer (GCIPL) and inner nuclear layer (INL) vo

32 NFL) and macular retinal ganglion cell-inner plexiform layer (GCIPL) change over time in healthy and

33 RNFL) thickness, macular ganglion cell-inner plexiform layer (GCIPL) thickness and optic nerve head (

34 er (pRNFL) and macular ganglion cell + inner plexiform layer (GCIPL) thinning in multiple sclerosis (

35 of the macular ganglion cell layer and inner plexiform layer (GCIPL) was -16.42 mum (-19.23 to -13.60

36 nglion cell layer (GCL), ganglion cell/inner plexiform layer (GCIPL), ganglion cell complex (GCC), an

37 nerve fiber layer, ganglion cell plus inner plexiform layer (GCIPL), whole-brain, gray matter and th

38 n cell complex (GCC) and ganglion cell inner plexiform layer (GCIPL), with the accuracy of RNFL param

39 e fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL).

40 of the retinal ganglion cell layer and inner plexiform layer (GCL + IPL).

41 Thicknesses of the ganglion cell layer/inner plexiform layer (GCL+IPL), RNFL, outer plexiform/inner n

42 derate glaucoma was mGCL combined with inner plexiform layer (IPL) (AUC = 0.915) and cpRNFL (AUC = 0

43 layer (GCL) (nasally and temporally), inner plexiform layer (IPL) (nasally), outer nuclear layer (ON

44 with ONHD had a significantly thinner inner plexiform layer (IPL) (P = 0.02), nerve fiber layer (P =

45 es stratify at different levels in the inner plexiform layer (IPL) and can interact with costratifyin

46 apses in the innermost ON layer of the inner plexiform layer (IPL) and from dopaminergic amacrine cel

47 rve fiber layer (NFL), and also in the inner plexiform layer (IPL) and inner nuclear layer (INL).

48 The location of the inner plexiform layer (IPL) and outer plexiform layer (OPL) wa

49 from bipolar and amacrine cells in the inner plexiform layer (IPL) and send information to the brain

50 nal amacrine cells migrate towards the inner plexiform layer (IPL) and then retract their trailing pr

51 branching in the outermost part of the inner plexiform layer (IPL) and weakly melanopsin-positive M2

52 t dACs send processes into the forming inner plexiform layer (IPL) before migrating through it and in

53 he division between the ON and the OFF inner plexiform layer (IPL) is not structurally absolute.

54 In the inner plexiform layer (IPL) of the mouse retina, ~70 neuronal

55 xon collaterals or terminals in the internal plexiform layer (IPL) on both sides of each bulb.

56 ls ramifying between 0% and 30% of the inner plexiform layer (IPL) receive mixed inputs from rods and

57 upregulated in regrowing RGC axons and inner plexiform layer (IPL) synapses, respectively.

58 cific arbor specializations within the inner plexiform layer (IPL) that occur consistently at defined

59 scleral half or "Off" sublamina of the inner plexiform layer (IPL) undergo the greatest changes, wher

60 In the distal 80% of the inner plexiform layer (IPL), dense GC dendrites coexisted with

61 SAC, found at the outer border of the inner plexiform layer (IPL), forms a synaptic subband "a" with

62 regation of ON and OFF pathways in the inner plexiform layer (IPL), where glutamate is released from

63 nals in the innermost sublamina of the inner plexiform layer (IPL), which is typical for mammals.

64 ; (4) restricted lamination within the inner plexiform layer (IPL), which renders J-RGCs responsive t

65 the ganglion cell layer, ~0.122 in the inner plexiform layer (IPL), ~0.025 in the inner nuclear layer

66 the inner or the outer portion of the inner plexiform layer (IPL).

67 ayering, or lamination, of the retinal inner plexiform layer (IPL).

68 and a dense layer in the middle of the inner plexiform layer (IPL).

69 dense layer of neuropil, the so-called inner plexiform layer (IPL).

70 mified in strata 1, 3, 4, and 5 of the inner plexiform layer (IPL).

71 her predominantly macula ganglion cell-inner plexiform layer (mGCIPL), predominantly peripapillary re

72 parameters and the ganglion cell layer-inner plexiform layer (mGCL-IPL) was determined by combining t

73 anglion cell layer (mGCL), and macular inner plexiform layer (mIPL) were significantly thinner in the

74 ar ganglion cell layer (mGCL), macular inner plexiform layer (mIPL), macular inner nuclear layer (mIN

75 ar inner nuclear layer (mINL), macular outer plexiform layer (mOPL), macular outer nuclear layer (mON

76 ng at the ganglion cell layer (n = 1), outer plexiform layer (n = 4), outer nuclear layer (n = 12), o

77 lion cell layer (NFL/GCL), NFL/GCL and inner plexiform layer (NFL/GCL + IPL), and total retina thickn

78 er ganglion cell layer (P = 0.003) and outer plexiform layer (OPL) (P < 0.001) compared with controls

79 hese areas included: subsidence of the outer plexiform layer (OPL) and inner nuclear layer (INL), and

80 es of HC axons fail to stratify in the outer plexiform layer (OPL) and invade the outer nuclear layer

81 l and optical property features of the outer plexiform layer (OPL) and the complex formed by the gang

82 n above (type 1) or below (type 2) the outer plexiform layer (OPL) at 6 tertiary referral centers.

83 correlating confirmed expansion of the outer plexiform layer (OPL) by optical coherence tomography (O

84 d as inner nuclear layer thinning with outer plexiform layer (OPL) disruption.

85 tinal layers limited externally by the outer plexiform layer (OPL) in 15 eyes (93.7%).

86 receptors mediating this action in the outer plexiform layer (OPL) is not clear.

87 is localized primarily throughout the outer plexiform layer (OPL) of the distal retina, a synaptic l

88 l confined to the inner portion of the outer plexiform layer (OPL) on PD-OCT.

89 drites (ORDs) either ramify within the outer plexiform layer (OPL) or the inner nuclear layer, and wh

90 he internal limiting membrane (ILM) to outer plexiform layer (OPL) was correlated with better postope

91 of the inner plexiform layer (IPL) and outer plexiform layer (OPL) was identified at each age, and it

92 not in the inner nuclear layer (INL), outer plexiform layer (OPL), or outer segment (OS) layer.

93 tina expresses several laminins in the outer plexiform layer (OPL), where they may provide an extrace

94 n the organization and assembly of the outer plexiform layer (OPL).

95 (ELM), outer nuclear layer (ONL), and outer plexiform layer (OPL).

96 thinning over an anteriorly displaced outer plexiform layer (OPL).

97 .006) or thinner average ganglion cell-inner plexiform layer (P = .028) along with higher baseline VF

98 ral macular retinal ganglion cell plus inner plexiform layer (RGC+IPL) loss identified by spectral-do

99 nglion cell layer (I3 and N6 sectors), inner plexiform layer (S6 and N6 sectors), inner nuclear layer

100 nuclear layer (T6 and N6 sectors), and outer plexiform layer (S6 sector), as well as the overall reti

101 rom the retinal ganglion cell layer to outer plexiform layer (standardized beta = 0.657 to 0.777, all

102 us inner plexiform layer, the INL plus outer plexiform layer (the combined thickness of these layers

103 cular (including the ganglion cell and inner plexiform layer [GCIPL], inner retina [IR], outer retina

104 ntibodies labeled RBC dendrites in the outer plexiform layer and axon terminals in the IPL, as well a

105 l of their axon terminal system in the inner plexiform layer and in immunoreactivity for recoverin an

106 ificantly fewer ribbon synapses in the outer plexiform layer and increased ectopic synapses in the ou

107 while the abnormal hyperreflectance of outer plexiform layer and inner nuclear layer on spectral-doma

108 estored; however, the thickness of the inner plexiform layer and one measure of axon branching were s

109 parameters, such as the ganglion cell inner plexiform layer and optic nerve head parameters, also ar

110 g: rods retracted their axons from the outer plexiform layer and partially degenerated, whereas cones

111 l nerve fibre layer, ganglion cell and inner plexiform layer and stopped at the level of the inner nu

112 stance between the outer border of the outer plexiform layer and the inner border of the ellipsoid zo

113 er and immunoreactive processes in the inner plexiform layer and the outer plexiform layer.

114 es depolarize TH cell dendrites in the inner plexiform layer and these depolarizations propagate to t

115 Although the inner plexiform layer appears earlier than the outer plexiform

116 ns without photoreceptors, leaving the outer plexiform layer apposed to the RPE.

117 ition, the synaptic connections in the outer plexiform layer are defective in Oc1-null mice, and phot

118 er, the synaptic mechanisms within the inner plexiform layer are not well characterized within specif

119 ression and synaptic structures in the outer plexiform layer are preserved, and visual responses are

120 r and 4mum for macular ganglion cell + inner plexiform layer are robust thresholds for identifying un

121 strongly associated with ganglion cell/inner plexiform layer atrophy (P = 0.004) and C1QA and CR1 wer

122 ed genetic predictors of ganglion cell/inner plexiform layer atrophy in a discovery cohort of 374 pat

123 e attributed to the disorganization of inner plexiform layer cells that occurs in the Dscam mutant re

124 Macular ganglion cell-inner plexiform layer complex (GCIPL) and peripapillary retina

125 drant, and a thinner ganglion cell and inner plexiform layer complex (GCL-IPL).

126 of significantly thicker GCL, IPL, and outer plexiform layer in the central retinal area (i.e., fovea

127 ed thickness of the ON sublayer of the inner plexiform layer in the microbat retina, more ON than OFF

128 cystoid spaces (72% vs 40%, P < .038), outer plexiform layer involvement (5% vs 96%, P < .001), ellip

129 onal synapses and gap junctions in the inner plexiform layer is also observed.

130 suggests that the organization of the outer plexiform layer is more complex than classically thought

131 We found that: (a) the outer plexiform layer is the most discriminative layer for cla

132 ing from the inner nuclear layer (INL)/outer plexiform layer junction to involve the full-thickness I

133 Average and quadrant ganglion cell-inner plexiform layer measures demonstrated CVs </=4.5% with e

134 plexiform layer neurites, and varicose outer plexiform layer neurites all bear spines, that some of t

135 TH cell somata, tapering and varicose inner plexiform layer neurites, and varicose outer plexiform l

136 was localized to the inner segment and outer plexiform layer of rod photoreceptors.

137 f synapses and synaptic ribbons in the outer plexiform layer of Sfxn3 (-/-) mice.

138 select neurons concentrated in the internal plexiform layer of the main olfactory bulb.

139 tina and were found to interact in the outer plexiform layer of the retina containing the photorecept

140 he organization of cells making up the outer plexiform layer of the retina in the absence of Dscam.

141 Synapses in the inner plexiform layer of the retina undergo short-term plastic

142 dependent cellular interactions in the outer plexiform layer overcome this variability to ensure the

143 of idiopathic ERM, deformation of the outer plexiform layer progresses and is associated with decrea

144 ent types of amacrine cells across the inner plexiform layer prompts that they should be also involve

145 .74, P < 0.0001) and the ganglion cell inner plexiform layer region of interest (R = -0.51, P < 0.000

146 = -0.78, P < 0.0001) and ganglion cell inner plexiform layer region of interest (R = -0.65, P = 0.000

147 specific types of RGCs and of specific inner plexiform layer sublaminae, opening new avenues for iden

148 naptic layers beginning in stereotyped inner plexiform layer sublaminae.

149 The inner plexiform layer surround inhibition comprised GABAergic

150 Minimum rim width (MRW), ganglion cell-inner plexiform layer thickness (GC-IPLT), and circumpapillary

151 (ETDRS </=35) had normal ganglion cell-inner plexiform layer thickness and normal mfERG findings.

152 between CS at 6 cpd and ganglion cell/inner plexiform layer thickness at inferotemporal and inferona

153 mRNFL) and macular ganglion cell layer-inner plexiform layer thickness were 3.5, 4.5, 3.0, 3.0, 2.5,

154 al retinal thickness and ganglion cell-inner plexiform layer thickness were measured using custom-des

155 er thickness and ganglion cell layer - inner plexiform layer thickness).

156 reproducible measures of ganglion cell-inner plexiform layer thickness.

157 polar cell markers and preservation of outer plexiform layer thickness.

158 cell complex, inner nuclear layer, and outer plexiform layer thickness.

159 The ganglion cell layer and inner plexiform layer thicknesses could predict axonal damage

160 well as composite ganglion cell layer+inner plexiform layer thicknesses in the eyes of patients with

161 is and increased nerve fibre layer and inner plexiform layer thicknesses.

162 be obtained by measuring the areas of outer plexiform layer thinning (adjusted R(2) = 0.93), externa

163 milar set of analyses of ganglion cell/inner plexiform layer thinning in a replication cohort (n = 37

164 threshold of 5mum and ganglion cell + inner plexiform layer threshold of 4mum for identifying unilat

165 GCL, p = 0.003), ganglion cell layer - inner plexiform layer volume (GCL-IPL, p = 0.005) and inner re

166 Inner plexiform layer volume of both eyes (IPL, right eye: p =

167 l complement, and the extension of the outer plexiform layer were diminished.

168 The synapses in the outer plexiform layer were extensively degenerated and replace

169 f the combined outer nuclear layer and outer plexiform layer when we compared MSNON or MSON eyes with

170 ing exclusively in sublamina S5 of the inner plexiform layer, (2) bistratified cells with dendrites i

171 ndritic stratification in the retina's inner plexiform layer, and details of dendritic branching.

172 present within the nerve fiber layer, inner plexiform layer, and inner and outer nuclear layers and

173 cant decline with age of only the GCL, inner plexiform layer, and inner nuclear layer thickness with

174 ated in the retinal nerve fiber layer, inner plexiform layer, and outer plexiform layer.

175 e acquired from the nerve fiber layer, outer plexiform layer, and retinal pigmented epithelium using

176 GCs co-stratify their dendrites in the inner plexiform layer, and that Tenm3(+) ACs require Tenm3 to

177 ner nuclear layer (INL), ~0.087 in the outer plexiform layer, and ~0.026 in the outer nuclear layer (

178 cells occupy strata 2, 3, and 4 of the inner plexiform layer, between the two bands formed by choline

179 ver high-acuity spatial signals to the inner plexiform layer, but outside the fovea, this spatial res

180 major targets of histamine are in the outer plexiform layer, but the retinopetal axons containing hi

181 to the inner and outer margins of the inner plexiform layer, co-stratifying with the processes of ot

182 ter degree in the OFF sublamina of the inner plexiform layer, corroborating the hypothesis that RGCs

183 s localized primarily in puncta in the inner plexiform layer, in amacrine cells, and in somata in the

184 splicing in the retinal ganglia cells, outer plexiform layer, inner nuclear layer, and outer nuclear

185 ation of photoreceptor synapses in the outer plexiform layer, leading to a progressive functional det

186 thickening of the inner nuclear layer, outer plexiform layer, or full retina.

187 IMS2 localization in the human retinal outer plexiform layer, Purkinje cells, and pancreatic islets.

188 ses extending into the ON-layer of the inner plexiform layer, similar to A8 amacrine cells described

189 exiform layer appears earlier than the outer plexiform layer, synaptic proteins, and ribbons are firs

190 re layer, the ganglion cell layer plus inner plexiform layer, the INL plus outer plexiform layer (the

191 Imaging throughout the inner plexiform layer, we found transient, rectified release a

192 his functional diversity arises in the inner plexiform layer, where inhibitory amacrine cells modulat

193 GL-dSACs are located in the internal plexiform layer, where they integrate centrifugal cholin

194 especially high concentrations in the outer plexiform layer, while lutein is much more diffuse at re

195 colocalizations of GluR1 and TH in the inner plexiform layer.

196 es as well as glutamate release in the outer plexiform layer.

197 ter degree in the OFF sublamina of the inner plexiform layer.

198 retina and dendrites growing into the inner plexiform layer.

199 run in a single, narrow stratum of the inner plexiform layer.

200 dendrites in the OFF sublamina of the inner plexiform layer.

201 s in the inner plexiform layer and the outer plexiform layer.

202 e functional ON/OFF subdivision of the inner plexiform layer.

203 centralmost (on and off) bands of the inner plexiform layer.

204 ing to new, more distal regions of the inner plexiform layer.

205 milar to those found in the vertebrate inner plexiform layer.

206 mifying in the different layers of the inner plexiform layer.

207 d to both ON and OFF strata within the inner plexiform layer.

208 on their dendrites and throughout the inner plexiform layer.

209 the dendrites in the sublaminae of the inner plexiform layer.

210 s, sparing the outer retina except the outer plexiform layer.

211 , redirecting their dendrites into the inner plexiform layer.

212 r layer and in synaptic boutons in the inner plexiform layer.

213 e consistent with synaptic loss in the inner plexiform layer.

214 glion cells and their processes in the inner plexiform layer.

215 neuronal connexin, is expressed in the outer plexiform layer.

216 atification in the ON sublamina of the inner plexiform layer.

217 containing histamine terminate in the inner plexiform layer.

218 c to AII and A17 amacrine cells in the inner plexiform layer.

219 tion of dendrites and axons within the inner plexiform layer.

220 iber layer, inner plexiform layer, and outer plexiform layer.

221 r the outer or the inner border of the inner plexiform layer.

222 mify within the outermost layer of the inner plexiform layer.

223 omplex formed by the ganglion cell and inner plexiform layers (GCL + IPL) provided the highest probab

224 the combined retinal ganglion cell and inner plexiform layers (RGCL+), and the inner nuclear layer (I

225 cose axons arborizing in the inner and outer plexiform layers after glutamatergic synapses depolarize

226 ce, hWtEPOR mice had thinner inner and outer plexiform layers and a greater number of amacrine cells.

227 r, ganglion cell, inner plexiform, and outer plexiform layers and increased thickness in the inner nu

228 duction-related machinery is present in both plexiform layers by fetal week 13.

229 and their terminals in the outer nuclear and plexiform layers in a developmentally regulated manner.

230 While the developmental sequence of plexiform layers in human retina has been characterized,

231 ll structures in the inner nuclear and outer plexiform layers in paraneoplastic vitelliform retinopat

232 Reduction of the ganglion cell and inner plexiform layers predicted greater axonal damage in pati

233 iated with progression of deformation of the plexiform layers, as central retinal thickness (CRT) did

234 nerve fiber (RNFL), ganglion cell, and inner plexiform layers, can be correlated with vision loss cau

235 the visibility of the SCS: disarrangement of plexiform layers, CRT, and multiple adhesion points betw

236 at the margin of the inner nuclear and inner plexiform layers, rather than the ganglion cell layer.

237 mple, changes in the ganglion cell and inner plexiform layers, the sites of the retinal ganglion cell

238 re generated in both the outer and the inner plexiform layers.

239 Plexiform lesions (PLs), the hallmark of plexogenic pulm

240 Vascular occlusion and complex plexiform lesions are hallmarks of the pathology of seve

241 ion of pulmonary arterioles and formation of plexiform lesions composed of hyperproliferative endothe

242 n emerges as a central molecular mediator of plexiform lesions in both experimental models and human

243 xpression of LRP1 was decreased in pulmonary plexiform lesions of patients with end-stage idiopathic

244 dothelium of remodeled pulmonary vessels and plexiform lesions of patients with pulmonary arterial hy

245 , media hypertrophy, adventitial thickening, plexiform lesions, vascular pruning) in this disease.

246 the presence of early and advanced complex (plexiform) lesions, when compared with either the SIV-in

247 ation, and various forms of obliterative and plexiform-like lesions in pulmonary arteries, similar to

248 remodeling, including vascular occlusion and plexiform-like lesions, resembling the hallmarks of the

249 uracy of semi-automated tumor volume maps of plexiform neurofibroma (PN) generated by a deep neural n

250 Plexiform neurofibroma (PN) tumors are a hallmark manife

251 irtually pathognomonic finding of NF1 is the plexiform neurofibroma (PN), a benign, likely congenital

252 , and facial structures (orbital-periorbital plexiform neurofibroma [OPPN]) can result in significant

253 ues define the cell of origin for murine Nf1 plexiform neurofibroma and leverage this finding to deve

254 cursors (SCP), which have been implicated in plexiform neurofibroma initiation.

255 Extent of orbitotemporal plexiform neurofibroma involvement was assessed clinical

256 Orbitotemporal plexiform neurofibroma location was classified as isolat

257 for sensitive measurement of orbitotemporal plexiform neurofibroma size, and larger volumes were ass

258 l subjects with amblyopia had orbitotemporal plexiform neurofibroma volumes greater than 10 mL.

259 Amblyopia secondary to the orbitotemporal plexiform neurofibroma was present in 13 subjects (62%)

260 Plexiform neurofibroma, a benign peripheral nerve tumor,

261 ngineered mouse model that accurately models plexiform neurofibroma-MPNST progression in humans would

262 nalysis to measure the change in size of the plexiform neurofibroma.

263 include myeloid leukemia, optic glioma, and plexiform neurofibroma.

264 and to have NF1 and a clinically significant plexiform neurofibroma.

265 Ki, as well as in the MPNST precursor lesion plexiform neurofibroma.

266 en studied in neurofibromatosis type 1 (NF1) plexiform neurofibromas (PNFs).

267 Plexiform neurofibromas (PNs) involving the eyelid, orbi

268 bal Ink4a/Arf loss and identified paraspinal plexiform neurofibromas and atypical neurofibromas.

269 Major superficial plexiform neurofibromas and symptomatic spinal neurofibr

270 objective response rate among patients with plexiform neurofibromas and to assess clinical benefit.

271 Plexiform neurofibromas are a hallmark of NF1 and result

272 Plexiform neurofibromas are benign nerve sheath Schwann

273 Plexiform neurofibromas are common NF1 tumors carrying a

274 Plexiform neurofibromas are one of the most common tumor

275 ptic pathway gliomas (OPGs) and orbitofacial plexiform neurofibromas are two of the more common ophth

276 ases, including the use of MEK inhibitors in plexiform neurofibromas associated with neurofibromatosi

277 with neurofibromatosis type 1 and inoperable plexiform neurofibromas benefited from long-term dose-ad

278 in which loss of NF1 in Schwann cells drives plexiform neurofibromas formation, additional loss of In

279 with neurofibromatosis type 1 and inoperable plexiform neurofibromas had durable tumor shrinkage and

280 No approved therapies exist for inoperable plexiform neurofibromas in patients with neurofibromatos

281 Imatinib mesylate could be used to treat plexiform neurofibromas in patients with NF1.

282 pe with neither externally visible cutaneous/plexiform neurofibromas nor other tumors.

283 M-PNST contained regions of nerve-associated plexiform neurofibromas or atypical neurofibromas and gr

284 bromatosis type 1 and symptomatic inoperable plexiform neurofibromas received oral selumetinib twice

285 eurofibromatosis type 1 (NF1) develop benign plexiform neurofibromas that frequently progress to beco

286 had neurofibromatosis type 1 and inoperable plexiform neurofibromas to determine the maximum tolerat

287 e or decrease from baseline in the volume of plexiform neurofibromas) was monitored by using volumetr

288 Patients commonly present with plexiform neurofibromas, benign but debilitating growths

289 han half of NF1 children with orbitotemporal plexiform neurofibromas, most commonly because of ptosis

290 reatment of neurofibromatosis type 1-related plexiform neurofibromas, which are characterized by elev

291 firmed RUNX1 protein overexpression in human plexiform neurofibromas.

292 l databases for children with orbitotemporal plexiform neurofibromas.

293 This unique murine model of PAH-like plexiform/obliterative arteriopathy induced via a two-hi

294 dels and human patients, induce formation of plexiform/obliterative lesions and defined the molecular

295 INL) than in the complex formed by the outer plexiform (OPL) and the Henle fiber layers (HFL): 5.0 x

296 s to ameliorate and, perhaps, reverse the EC plexiform phenotype in severe human PAH.

297 Dense and plexiform structure of AVM nidus as well as a low number

298 0% or more decrease in volume of one or more plexiform tumours.

299 mples in the odontoblast cluster were of the plexiform type (p < 0.05).

300 localized to the abluminal side of the outer plexiform vascular endothelial cells, Muller glia cells,