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1 uring oogenesis, we show that it is toxic to pole cells.
2 embryogenesis to minimize its inheritance by pole cells.
3 blish a repressive chromatin architecture in pole cells.
4 transcriptional activator, Bicoid (Bcd), in pole cells.
5 to downregulate terminal signaling in early pole cells.
6 tightly correlated with failure to form the pole cells.
7 g is absent from the base of the presumptive pole cells.
8 furrow, cellularization and formation of the pole cells.
9 hter nuclei, leading to its segregation into pole cells.
10 mitosis and S phase is blocked in quiescent pole cells.
11 n give rise to the germ cell progenitors, or pole cells.
12 h a mitotic cyclin did not induce mitosis in pole cells.
16 y cessation of sisA transcription in budding pole cells and persistent high-level sisA expression in
17 actors are also expressed in blastula animal pole cells and promote pluripotency in both cell types.
19 minal signaling is known to be attenuated in pole cells, and this raises the question of how this is
20 Embryos laid by dart5 mutants fail to form pole cells, and Tudor localization is disrupted in stage
21 med germ cells in many other eukaryotes, the pole cells are distinguished from the soma by their tran
24 nogaster, the germline precursor cells, i.e. pole cells, are formed at the posterior of the embryo.
25 asurement of their DNA content indicate that pole cells become quiescent in G2 phase of the cell cycl
26 rated in the oosome and is taken up into the pole cells before evidence of Nv-hb repression is observ
32 igrans oskar rescues the body patterning and pole cell defects of embryos from D. melanogaster oskar(
33 ue of chimeras composed of animal or vegetal pole cells derived through normal cleavage to the 8-cell
34 cription prior to pole cell formation in the pole cell-destined nuclei, this silencing does not occur
37 We characterize defects in cellularization, pole cell formation and cytokinesis in a series of mater
38 eric/centric heterochromatin, the defects in pole cell formation are associated with alterations in t
39 ntrol embryos silence transcription prior to pole cell formation in the pole cell-destined nuclei, th
40 these structures, Aubergine is required for pole cell formation independently of its initial role in
41 2) is required for proper nuclear migration, pole cell formation, and cellularization during the earl
43 he nuclear envelope is crucial for promoting pole cell formation, but not necessary to initiate and f
44 d Oskar, Aubergine remains cytoplasmic after pole cell formation, suggesting that the roles of these
47 clusively within the female germline rescues pole-cell formation, whereas ubiquitous expression rescu
48 bo in the border cell rosette and Cut in the pole cells have antagonistic interactions to restrict Fa
51 e germ plasm interacts with these nuclei for pole cell induction and is selectively incorporated into
53 The predetermination probably involves soma/pole-cell interaction in the anterior half of the embryo
56 Despite suffering aberrant divisions at the poles, cells lacking the minCDE operon (Min(-)) have an
61 a melanogaster, germ cell precursors (called pole cells) proliferate early in embryogenesis and then
63 and Gata5 are unable to induce cas in animal pole cells, suggesting that cas expression requires an a
66 onent necessary for the proper formation of "pole cells," the germ cell precursors in Drosophila, is
67 actions to restrict Fas2 accumulation to the pole cells, which is important for proper border cell mi
68 loser to the N terminus blocks separation of pole cells with less effect on cellularization, highligh