ライフサイエンスコーパス: polyploid

1 re of mixed ancestry and/or are aneuploid or polyploid.

2 ccumulated mutation by virtue of their being polyploid.

3 ccales and P. furiosus is suspected of being polyploid.

4 nnot know the exact founders of a particular polyploid.

5 coded as apomictic or sexual and diploid or polyploid.

6 erentiation is often significantly faster in polyploids.

7 upporting a 'jack-and-master' hypothesis for polyploids.

8 ts were linked to the delayed development of polyploids.

9 spire to shape the evolutionary potential of polyploids.

10 tion has not been commonly observed in plant polyploids.

11 le-locus karyotypes are very common, even in polyploids.

12 ossible reason for the success and spread of polyploids.

13 d gene expression remolding in the resulting polyploids.

14 a key factor governing gene transcription in polyploids.

15 sms helped to favor the domestication of the polyploid A. hypogaea over other diploid Arachis species

16 Polyploid AAV vectors can be generated from any AAV sero

17 ) present in each of three sets of 50 mostly polyploid accessions, for four loci, in three PacBio run

18 e essential ecological mechanisms underlying polyploid adaptation to heterogeneous environments, and

19 resence of multiple homologs or homeologs in polyploids affords greater tolerance to mutations that c

20 unt of niche overlap and breadth between the polyploid and progenitors.

21 a, but it remains unclear how Sequoia became polyploid and why this lineage overcame an apparent gymn

22 tations, antheridiogens may be beneficial to polyploids and apomicts.

23 in trait means but not plasticities between polyploids and diploids, suggesting that increased genom

24 ole of the subpopulation of CMs that are not polyploid, and (e) speculations as to why CMs become pol

25 omegalic nuclei from Fan1(nd/nd) kidneys are polyploid, and fibroblasts from Fan1(nd/nd) mice become

26 s are valuable for the evolutionary study of polyploids, and may shed light on studies of hybrid vigo

27 and economical to study the phylogenetics of polyploids, and, in conjunction with recent analytical a

28 al limb shape and tube length, and that most polyploids are distinct or transgressive in at least one

29 We found that polyploids are often more climatically differentiated fr

30 posed of diploid sexual and both diploid and polyploid asexual (i.e., apomictic) lineages.

31 d, and (e) speculations as to why CMs become polyploid at all.

32 d evaluate a practical implementation of the polyploid-aware mixture model that quickly and accuratel

33 restimate aneuploidy levels, especially in a polyploid background.

34 Polyploid bacteria are common, but the genetic and funct

35 y-partition problem of the reads, called the Polyploid Balanced Optimal Partition model.

36 n is available, the model is extended to the Polyploid Balanced Optimal Partition with Genotype const

37 shable from human embryos at the blastomere, polyploid blastomere, compaction, morula and blastocyst-

38 In this study, we genotyped polyploid blueberries, including 105 SHB, 17 NHB, and 10

39 ficient ROS to trigger genome instability in polyploid C. albicans cells.

40 Switchgrass (Panicum virgatum), a perennial, polyploid, C4 warm-season grass is among the foremost he

41 Polyploid cancer cells exhibit chromosomal instability (

42 understand chromosome instability typical of polyploid cancer cells.

43 phase progression, which led to formation of polyploid cardiomyocyte nuclei in neonatal mice, which,

44 were found to be CDC20(low)SPG20(high) while polyploid cardiomyocytes that replicated DNA but failed

45 isting minimum fragment removal model to the polyploid case and on new integer linear programs to rec

46 ly degraded by acetylated Skp2, resulting in polyploid cell division, genomic instability, and oncoge

47 o quantify aneuploidy, a possible outcome of polyploid cell divisions.

48 begun to elucidate the signals required for polyploid cell growth as well as the advantages and disa

49 Tissue repair usually requires either polyploid cell growth or cell division, but the molecula

50 romotes the diploid-polyploid conversion and polyploid cell growth through the Akt-Skp2 axis.

51 takes 2-3 months and can be applied to other polyploid cell lines or high-copy-number genes.

52 Thus, disrupting genes in polyploid cell lines or when using poorly performing sgR

53 riptional drivers of all but the most highly polyploid cell types of the placenta.

54 Moreover, the changes in polyploid cell wall composition promoted saccharificatio

55 quitination of histone-H2A at lysine-119) in polyploid cell.

56 Here we show that polyploid cells accumulate in the adult fly brain and th

57 identifies inhibitors of bipolar division in polyploid cells and provides a rationale to understand c

58 ntial recognition of autophagy-competent and polyploid cells by the innate and cellular immune system

59 p53-mediated suppression of proliferation of polyploid cells can be averted by increased levels of on

60 end points are preceded by the appearance of polyploid cells caused by the suppression of Aurora kina

61 How polyploid cells deal with increased centrosome numbers a

62 embly in polyploid cells, we found that most polyploid cells divide in a multipolar manner.

63 pite its prevalence, major gaps exist in how polyploid cells emerge and affect tissue function.

64 While most cells maintain a diploid state, polyploid cells exist in many organisms and are particul

65 The newly discovered versatility of polyploid cells has the potential to provide alternative

66 0% in humans, the specialized role played by polyploid cells in liver homeostasis and disease remains

67 allele system to genetically label and trace polyploid cells in situ.

68 leads to an earlier onset of polyploidy, and polyploid cells in the adult brain are more resistant to

69 igenesis, primarily because cell division in polyploid cells is error-prone and produces aneuploid ce

70 where haploid 5-mum cells convert to highly polyploid cells of >10 mum with distinct but poorly unde

71 known about the fates or functions of these polyploid cells or how they affect development of liver

72 ary infection, cryptococcal cells form large polyploid cells that exhibit increased resistance to hos

73 ientation of individual chromosomes in large polyploid cells would not hamper reproductive success as

74 ive stress promotes the appearance of highly polyploid cells, and antioxidant-treated NAFLD hepatocyt

75 ogressing through the cell cycle faster than polyploid cells, both in vitro and during liver regenera

76 r cells to study mitotic spindle assembly in polyploid cells, we found that most polyploid cells divi

77 intain meiosis can result in highly aberrant polyploid cells, which could lead to oncogenesis in the

78 were specifically exposed on the surface of polyploid cells, yet lost upon passage of such cells thr

79 ribed changes with respect to development in polyploid cells.

80 ved in chronically damaged liver tissues, on polyploid cells.

81 agging chromosomes or micronuclei in mitotic polyploid cells.

82 n return to mitotic growth and go on to form polyploid cells.

83 Given that mitochondrial genomes are polyploid, cells with advantageous levels of mtDNA mutat

84 rstand commonalities that derive from shared polyploid cellular processes across organismal diversity

85 ant after a single episode of random mating, polyploids, characterized by polysomic inheritance, appr

86 al and conceptual difficulties in defining a polyploid CM, (b) the candidate role of reactive oxygen

87 to elucidate the origin and evolution of the polyploid complex.

88 ogenetic range of the Campanula rotundifolia polyploid complex.

89 ive isolation among three cytotypes within a polyploid complex.

90 which may slow divergence and speciation in polyploid complexes.

91 atocytes (tetraploid, octaploid, etc.), with polyploids comprising >=90% of the hepatocyte population

92 od (Sequoia sempervirens) is one of just two polyploid conifer species and the only hexaploid.

93 po pathway effector Yap promotes the diploid-polyploid conversion and polyploid cell growth through t

94 vergence of the transcriptional network in a polyploid crop and offer a new approach for assessing pa

95 describe the circadian transcriptome in the polyploid crop Brassica rapa.

96 ng the directional effects of selection in a polyploid crop genome.

97 umber of such gene-based markers is small in polyploid crop plants such as allotetraploid cotton that

98 underpin association genetics studies in the polyploid crop species Brassica napus (oilseed rape).

99 Here we focus our analysis on soybean, a polyploid crop with a highly duplicated genome, relative

100 nst the genome assembly for their particular polyploid crop.

101 We demonstrate expVIP's suitability for polyploid crops and evaluate its performance across a ra

102 Understanding the diversification of polyploid crops in the circum-Mediterranean region is a

103 g various growth and developmental traits in polyploid crops, having a complex G-protein signalling n

104 However, as for other polyploid crops, sequencing costs still hinder the imple

105 diploid model organisms, are missing in many polyploid crops.

106 ed in powerful reverse genetic approaches in polyploid crops.

107 ic engineering, breeding, and improvement of polyploid crops.

108 uction and for further evolution analysis of polyploid crops.

109 d methods developed herein can benefit other polyploid crops.

110 ategies is assigning function to paralogs in polyploid crops.

111 ision and normal organ development occurs in polyploid, DDR-impaired Drosophila papillar cells.

112 m three diploid cytotypes, their hybrids and polyploid derivatives.

113 Kinematic analysis showed that polyploids developed slower compared to diploids; howeve

114 Chloroplast genomes are organized as a polyploid DNA-protein structure called the nucleoid.

115 gesting that increased genomic redundancy in polyploids does not necessarily translate into greater t

116 ed insertion method to knockout genes in the polyploid Drosophila S2R+ cell line.

117 n response to anthracnose infection, whereas polyploid duplicates are not, supporting the general vie

118 Selective sweeps were enriched among polyploid duplicates encoding key developmental and phys

119 n undergo endoreduplication, confounding the polyploid effect.

120 traploid S. viminalis var. Energo genotypes (polyploid Energo [PP-E]; 2n = 4x = 76) with variation in

121 Disentangling the evolutionary histories of polyploids, especially those with high ploidies, can rev

122 croclimate factors may play a larger role in polyploid establishment than previously hypothesized.

123 hock that occurs following hybridization and polyploid events and may also contribute to uncovering t

124 cilitates investigation of broad patterns of polyploid evolution.

125 heterogeneous garden environments, however, polyploids exhibited fitness advantage, which was confer

126 rait divergence and plasticity in conferring polyploid fitness advantage in heterogeneous environment

127 c shock' and environmental adaptation during polyploid formation and evolution.

128 oid parents of T. castellanus, and that this polyploid formed at least three times.

129 N subgenome has undergone a substantial post-polyploid fractionation.

130 Allium lineages with high polyploid frequencies had higher species diversification

131 han those of diploids or lineages with lower polyploid frequencies.

132 : (1) the relationship between intraspecific polyploid frequency and species diversification rate; an

133 r study emphasises the role of intraspecific polyploid frequency combined with ecological drivers on

134 An increased polyploid frequency may facilitate speciation through sh

135 o assemble haplotypes of highly heterozygous polyploids from Illumina short-sequencing reads.

136 id WGDs and how diploidization affected post-polyploid gene retention.

137 Our study provides insights into polyploid genome evolution and valuable resources for ge

138 Our understanding of polyploid genome evolution is constrained because we can

139 ts of the predictability of patterns of post-polyploid genome evolution.

140 grain crop and for fundamental insights into polyploid genome evolution.

141 reconstructing the multiple haplotypes of a polyploid genome from its sequence reads becomes practic

142 The polyploid genome provided insights into the evolution of

143 on years, the reduction of redundancy of the polyploid genome seems to have been remarkably random.

144 s hypogaea L.) is of hybrid origin and has a polyploid genome that contains essentially complete sets

145 dancy and allow the hidden potential of this polyploid genome to be discovered.

146 Given the complexity of a polyploid genome with its phenomena of homoeologous expr

147 to the physical chromosome organization of a polyploid genome, as well as on the relationship between

148 ically been challenging due to its large and polyploid genome, limited genetic diversity and in-field

149 udy the evolutionary dynamics of a large and polyploid genome, specifically the impact of single gene

150 rs that distinguish subgenome sequences in a polyploid genome.

151 pment of new analyses and views to represent polyploid genomes (of which bread wheat is the primary e

152 However, cultivated mints have complex polyploid genomes and are sterile.

153 Although these polyploid genomes are conserved in gene content and synt

154 d the temporal evolutionary dynamics of four polyploid genomes at both genetic and expression levels.

155 tiple lines of evidence, as well as to phase polyploid genomes in a single integrative framework, sub

156 ich is challenging given the large and often polyploid genomes of plants.

157 t is difficult to obtain homozygous edits of polyploid genomes when the editing efficiency is low.

158 uences, but assemblies of large, repeat-rich polyploid genomes, such as that of bread wheat, remain f

159 anging from small to gigantic repeat-rich or polyploid genomes.

160 pportunities to investigate the evolution of polyploid genomes.

161 ant hybridization, reproductive biology, and polyploid genomics.

162 Polyploid giant cancer cells (PGCC) are common in tumors

163 Our recent perplexing findings that polyploid giant cancer cells (PGCCs) acquired embryonic-

164 The efficiency and simplicity of CRISPRi in polyploid Giardia allows rapid evaluation of knockdown p

165 Polyploid granuloma-resident macrophages formed via modi

166 switch from the proliferative cell cycle to polyploid growth and multinucleation in lung cancer cell

167 Each polyploid had at least partial geographic sympatry and a

168 re accurate than the recent state-of-the-art polyploid haplotyping algorithms.

169 However, the computational challenge in polyploid haplotyping is much greater than that in diplo

170 This article models the polyploid haplotyping problem as an optimal poly-partiti

171 nderlying a particular trait are reshaped in polyploids has not been experimentally investigated.

172 Difficulties in generating nuclear data for polyploids have impeded phylogenetic study of these grou

173 The liver contains diploid and polyploid hepatocytes (tetraploid, octaploid, etc.), wit

174 In summary, we identified new roles for polyploid hepatocytes and demonstrated that they are req

175 Polyploid hepatocytes are commonly found in adult mammal

176 ompared with control hepatocytes, suggesting polyploid hepatocytes are required for production of ane

177 Mice with increased polyploid hepatocytes develop fewer liver tumors followi

178 Polyploid hepatocytes form multipolar spindles in mitosi

179 In addition, diploid or polyploid hepatocytes from wild-type (WT) mice were exam

180 ; however, it is unclear whether diploid and polyploid hepatocytes function similarly in multiple con

181 We therefore conclude that polyploid hepatocytes have extensive regenerative capaci

182 We also traced polyploid hepatocytes in several different liver injury

183 Remarkably, polyploid hepatocytes maintain the ability to regenerate

184 Diploid and polyploid hepatocytes responded similarly to hepatic mit

185 t of intense study, and the contributions of polyploid hepatocytes to organ regeneration and homeosta

186 Multicolored polyploid hepatocytes undergo ploidy reduction and subse

187 ted levels on BALB/cByJ hepatocytes and also polyploid hepatocytes, might facilitate Plasmodium liver

188 and observed profound, lifelong depletion of polyploid hepatocytes, proving that miR-122 is required

189 rmal postnatal liver development, leading to polyploid hepatocytes.

190 We also considered ambiguity in polyploid heterozygote genotyping and developed a weight

191 sexual relatives, potentially generating new polyploid hybrid lineages.

192 Using new polyploid hybrids made from the ancestral species, we sh

193 nd glia that are diploid at eclosion, become polyploid in the adult Drosophila brain.

194 r community context and how the emergence of polyploids in populations could also alter the community

195 he shift was niche intermediacy in which the polyploid inhabited a geographic range between that of t

196 d, they function independently to facilitate polyploid intermediates in the production of many progen

197 Haplotype assembly of polyploids is an open issue in plant genomics.

198 at one of the parental subgenomes in ancient polyploids is generally more dominant, having retained m

199 on and homoeolog expression divergence among polyploid lineages.

200 Toll-like receptor (TLR) 2 signal instructs polyploid macrophage fate by inducing replication stress

201 High sequence similarity between genomes in polyploids means that if primers are not homeologue-spec

202 ns that ultimately lead to the production of polyploid megakaryocytes.

203 RhoA/ROCK pathway that has a low activity in polyploid megakaryocytes.

204 oreduplication followed by late divisions of polyploid mesocarp cells, which consequently acquire the

205 We show that polyploid morphological divergence from the intermediate

206 It is thought that formation of polyploid nuclei establishes a barrier for cardiomyocyte

207 is, tubular degeneration, and characteristic polyploid nuclei in multiple tissues.

208 uced karyokinesis and increased formation of polyploid nuclei.

209 ield QTL in cultivated rice, from four Oryza polyploids of various ages and their likely diploid geno

210 Polyploid organisms such as wheat complicate even the si

211 Empirical Bayes techniques to genotype polyploid organisms usually either (i) assume technical

212 arguing that it is particularly relevant in polyploid organisms.

213 struct unspecified haplotypes in diploid and polyploid organisms.

214 e sequence of peanut and show that after its polyploid origin, the genome has evolved through mobile-

215 To reconstruct their polyploid origin, we phased the genomes of two ale strai

216 ry, and highlights the pitfalls of inferring polyploid origins from niche/range alone or combined wit

217 In the recently formed BBCC polyploid, Oryza minuta, genome dominance was not observ

218 the fruit fly Drosophila melanogaster, where polyploid ovarian follicle cells amplify genomic regions

219 , illustrating another axis of advantage for polyploids over diploids.

220 Large polyploid PCs are outnumbered by RSCs, which replace eac

221 ve developed a computational method based on polyploid phasing of long sequence reads to resolve coll

222 By integrating linkage mapping, polyploid phylogeny and sex-determining region (SDR) in

223 the relationship between DNA methylation and polyploid plant domestication remains elusive.

224 during evolution, the origins of many extant polyploid plant species remain largely unknown.

225 several monocots/dicots, diploid as well as polyploid plant species.

226 Polyploid plants displayed greater generalization in bac

227 Evidence for this mechanism comes from polyploid plants, bacteria, and archaea.

228 panying crop domestication, particularly for polyploid plants.

229 sight into the prevalence and persistence of polyploid plants.

230 ew approaches for improving cotton and other polyploid plants.

231 ploids (fungi), diploids (most mammals), and polyploids (plants).

232 rsal efficiency of this intein in a natural, polyploid population.

233 ating tetraploid cells can emerge from acute polyploid populations.

234 They are produced by large polyploid precursor cells called megakaryocytes.

235 r AutoCloner provides a simple and effective polyploid primer-design method for gene cloning, with no

236 th lager and baking strains, ale strains are polyploid, providing them with a passive means of remain

237 Moreover, sturgeons are notoriously polyploid, providing unique opportunities to investigate

238 ch subgenome dominates within a newly formed polyploid remain poorly understood.

239 We addressed these issues in a polyploid representative of Hydatellaceae, part of the w

240 tton species also provide a model system for polyploid research, of relevance here because polyploidy

241 ccurate SNP yield possible from low-coverage polyploid sequence data.

242 bacteroids are terminally differentiated and polyploid, similar to bacteroids in IRLC legumes.

243 , condensins of the germline nucleus and the polyploid somatic nucleus are composed of different subu

244 ntally altered chromosome arrangement in the polyploid somatic nucleus: multiple copies of homologous

245 differentiation is an important component of polyploid speciation and that niche differentiation is o

246 Polyploid speciation entails substantial and rapid postz

247 ts, we tested whether the climatic niches of polyploid species are more differentiated than their dip

248 ccurately identifying transcript isoforms in polyploid species because of the high sequence similarit

249 Here we characterize AS in the polyploid species cotton.

250 loid relatives and if the climatic niches of polyploid species differentiated faster than those of re

251 sistent with this pattern, we estimated that polyploid species generally have higher rates of multiva

252 Complexes of diploid and polyploid species have formed frequently during the evol

253 The sequences among subgenomes in a polyploid species have high similarity, making it diffic

254 Young polyploid species such as wheat, which was domesticated

255 ether with genome editing, are being used in polyploid species to combine mutations in all copies of

256 In polyploid species, altering a trait by random mutagenesi

257 e as a general strategy for sequencing other polyploid species.

258 ize genomic prediction for other diploid and polyploid species.

259 and will enhance our understanding of AS in polyploid species.

260 l for developing similar resources for other polyploid species.

261 faster than polyploids, suggesting that the polyploid state functions as a growth suppressor to rest

262 The polyploid state reduces spontaneous mutation accumulatio

263 in an irreversible, strongly elongated, and polyploid state.

264 Ploidy (diploid vs polyploid states) and breeding system (self-incompatible

265 The mechanisms of polyploid success in ecologically relevant contexts, how

266 on has long been thought to be important for polyploid success.

267 undancy is more extensive in recently formed polyploids such as wheat, which can now benefit from the

268 have more than two sets of chromosomes are 'polyploid' such as 'triploid' (3n), 'tetraploid' (4n), '

269 s to the related diploid Sorghum and complex polyploid sugarcanes.

270 Thus far, community-level studies of polyploids suggest an array of outcomes, from no changes

271 Diploid hepatocytes proliferate faster than polyploids, suggesting that the polyploid state function

272 related to the large, highly repetitive and polyploid switchgrass genome, to perform genome-wide ass

273 In addition, we show that polyploids tend to evolve shorter and wider corolla tube

274 ins a mixture of hepatocytes with diploid or polyploid (tetraploid, octaploid, etc.) nuclear content.

275 from the cyclin E1-overexpressing mice were polyploid than from control mice, and had losses or gain

276 otic isolation was weaker among higher order polyploids than between diploids and tetraploids, and un

277 ing much-needed model systems of established polyploids that have been, and remain to be, recognized.

278 In mammals, most cardiomyocytes (CMs) become polyploid (they have more than two complete sets of chro

279 As papillar cells become polyploid, they naturally accumulate broken acentric chr

280 e we evaluate CIN in human cells that become polyploid through an experimentally induced endoreplicat

281 These polyploid titan cells can generate haploid and aneuploid

282 part of the diploidisation process returning polyploids to a diploid-like state over time.

283 olyMarker is available as a ruby BioGem: bio-polyploid-tools.

284 Consequently, polyploid trypanosomes containing 8C equivalent of DNA p

285 f chromosomal loci in the very large, highly polyploid, uncultivated intestinal symbiont Epulopiscium

286 and fibroblasts from Fan1(nd/nd) mice become polyploid upon ICL induction, suggesting that defective

287 e evolution of gene expression regulation in polyploid vertebrates.

288 These results indicate that polyploid viruses might potentially acquire advantages f

289 Polyploids were reduced fourfold in LKO livers, and LKO

290 In whole-organism polyploids, WGD has been implicated in adaptability and

291 anscription factors regulating senescence in polyploid wheat (Triticum aestivum).

292 cription factors that regulate senescence in polyploid wheat and exemplifies the integration of time-

293 nsposons to maintain genome stability during polyploid wheat evolution.

294 With this fully assembled polyploid wheat genome, we identified the causal mutatio

295 type found in T. monococcum was not found in polyploid wheat, suggesting an opportunity to introduce

296 ength affects final grain size and weight in polyploid wheat.

297 the course of domestication and evolution of polyploid wheats.

298 y-automate primer design for gene cloning in polyploids, where previously the consensus within the wh

299 oid gene flow, especially among higher order polyploids, which may slow divergence and speciation in

300 plants on these N + P plots are dominated by polyploids with large GS and a competitive plant strateg