ライフサイエンスコーパス: positional

1 pursuit using measures of velocity accuracy, positional accuracy and positional variability.

2 In this manner we find the average positional accuracy as well as the isotropic and anisotr

3 acy as well as the isotropic and anisotropic positional accuracy associated with each atom in a cryst

4 ating FRB observations have had insufficient positional accuracy to localize them to an individual ho

5 get surface, and use it to achieve sub-50 nm positional accuracy.

6 ocesses named Rock and Roll, is required for positional acquisition of HCs.

7 inge induces slow conformational changes and positional alternations of both subdomains with respect

8 The kinase-specific positional amino acid preferences are learned using a bi

9 In this Perspective, positional analogue scanning is shown to be an effective

10 ofiling of an efficiently prepared series of positional analogues stemming from the systematic exchan

11 One module can be used for the positional analysis of an individual animal, amenable to

12 Positional analysis of lincRNA loci implicated involveme

13 y combining mouse genetics with quantitative positional analysis, we found that motor neuron organiza

14 ccurs through pressure-dependent correlative positional and conformational changes in the connector.

15 arenes and alkenes with excellent levels of positional and diastereo-selectivity, avoiding the use o

16 approach is demonstrated to differentiate sn-positional and double-bond-positional isomers, such as t

17 ternal derangement is defined as an abnormal positional and functional relationship between the disc

18 ces in any desired arrangement, with precise positional and orientational control.

19 ions need to address confounding of allelic, positional and regional effects as well as imbalance of

20 Our findings define the positional and sequence determinants for initial-transcr

21 nomics data such as curated protein sequence positional annotations from UniProtKB, as well as mapped

22 gial cell types with posturomotor, oromotor, positional-autonomic, orienting, and vigilance circuits.

23 ion along dorso-ventral and antero-posterior positional axes.

24 This is mainly due to the almost ubiquitous positional B/C disorder, rendering the description of re

25 numbers of vertebrae based on running speed, positional behaviour and vertebral contribution to locom

26 e fusion contrasts with the current inferred positional behaviour of the earliest hominins, thus sugg

27 vides evidence of a newly identified form of positional behaviour-extended limb clambering.

28 e used large-scale in vitro TF binding data, positional bias, and evolutionary conservation.

29 we introduce a multi-allelic version of the Positional Burrows-Wheeler Transform (mPBWT) based on th

30 The celebrated Positional Burrows-Wheeler Transform (PBWT) data structu

31 Positional Burrows-Wheeler Transform (PBWT) provides an

32 ressed representation of haplotype data, the positional Burrows-Wheeler transform, and multi-threaded

33 implementation of the graph extension of the positional Burrows-Wheeler transform.

34 s very similar to, and generalizes, Durbin's positional Burrows-Wheeler transform.

35 d differential expression of type I IFN as a positional candidate for an expression quantitative trai

36 GAT1) gene turned out to be a functional and positional candidate gene.

37 ntified using the chip to refine the list of positional candidate genes and identify potential causat

38 The next step was to search for positional candidate genes and QTLs within strong LD gen

39 ts and to identify genomic regions and their positional candidate genes associated with performance t

40 Ps in these QTL regions were annotated in 11 positional candidate genes related to osteogenesis, skel

41 A total number of 645 positional candidate genes were identified in strong LD

42 Thirty-eight positional candidate genes were identified within these

43 428 of the positional candidate genes were located within growth re

44 Using all positional candidate genes, a network was then construct

45 the INO80 complex-associated gene NFRKB as a positional candidate in 11q24.3.

46 In vitro studies of positional candidates confirmed CPNE1 and STC2 as modifi

47 Thirty-eight positional candidates distributed across five loci overl

48 We demonstrate major nucleosome positional changes associated with developmental gene re

49 ions to biomechanical corneal properties and positional changes have not been examined directly to in

50 eta aggregation diminishes with sequence and positional changes in the surface functionalities.

51 lex remodels chromatin via conformational or positional changes of nucleosomes, thereby altering the

52 al 23S ribosomal RNA (rRNA) nucleotide A1913 positional changes that are dependent on whether the cod

53 d then identified Delta160E mutation-induced positional changes.

54 n loci and risk loci have been identified by positional cloning and by genome-wide association studie

55 We report here the positional cloning and functional characterization of Pm

56 a strong genetic component, and so far, only positional cloning and genomewide association studies ha

57 vulgare CCT Motif Family gene 7, HvCMF7) by positional cloning as well as its functional validation

58 nd orienting annotated genome assemblies and positional cloning of candidate genes.

59 o illustrate the utility of our tool for the positional cloning of resistance genes, we estimated the

60 Here, we report positional cloning of the gene responsible for productio

61 alysis of resulting F(2) progeny followed by positional cloning showed that resistance to an isolate

62 Within the last 30 years, with the advent of positional cloning, the human genome project, solid-stat

63 We used a positional cloning-candidate gene approach to identify m

64 n this study the madC gene was identified by positional cloning.

65 s, packaging, to light-weight structural and positional components.

66 s were evaluated; one provided simple visual positional confirmation of sound source location, a seco

67 rom nearly 140,000 individuals to analyze 3D positional conservation in 4,715 proteins and 3,951 homo

68 ng to the relative entropy computed from the positional conservations and grouped into several 'block

69 In planarians, positional control genes (PCGs) control regeneration out

70 ctures are designed with different levels of positional correlation encoded by the degree of stealthi

71 Furthermore, positional correlation primarily affects conductivity, w

72 onclude that reducing energetic disorder and positional correlation, while increasing positional diso

73 widespread residue flipping and instances of positional coupling.

74 icted downregulation of YAP/TAZ provides the positional cue and allows smooth muscle cell differentia

75 PopZ to the new pole, thereby eliminating a positional cue for centromere translocation.

76 er, orderly positioning of axon terminals by positional cues and synaptic activity is required for ap

77 t structures of ZapA-ZapB provide additional positional cues for Z-ring formation and may help coordi

78 bryonic and extra-embryonic tissues provides positional cues to drive shape changes in mammalian deve

79 cell tracking permitted rapid acquisition of positional data and robust statistical analyses for migr

80 Using automated tracking of positional data for large sample sizes of single migrati

81 rned reward location, which in turn improved positional decoding near this location.

82 resented Spliceman, an online tool that used positional dependence to predict how likely distant muta

83 use the interaction of not just keywords but positional dependencies (e.g. a relevant word occurs 5 r

84 through microfluidic channels to resolve the positional dependencies of the resistive pulses.

85 d T1-weighted MR images in all cases, with a positional discrepancy of less than 2 mm.

86 ngs indicate that local stroma might control positional disease patterns not only in arthritis but in

87 We find that positional disorder aids the formation of new conduction

88 ieved using modeling that has focused on the positional disorder among the identical, multilayered ri

89 and positional correlation, while increasing positional disorder can lead to higher TE power factors.

90 A static positional disorder is proposed for the interlayer CH(3)

91 e inverse-participation ratio, by tuning the positional disorder of arrays of interacting mesas.

92 Realizing such positional disorder of identical nanostructures is diffi

93 anoparticle to fully populate its stationary positional distribution achieve a spatial averaging that

94 transfer experiments designed to monitor the positional distribution of TM6 did not detect the presen

95 "regionally specific" sQTLs showed distinct positional distributions of single-nucleotide polymorphi

96 The model predicts the statistics of positional distributions, shapes, and overlaps of each c

97 We find that nuclear positional dynamics is sensitive to the cytoskeletal org

98 er, our results suggest that mapping nuclear positional dynamics provides important insights into bio

99 ed CFTR as a model system to investigate the positional effect of the PTC because of its well-underst

100 xanthin concentration is to be achieved, the positional effect should be taken into consideration as

101 groups on the inositol ring, with phosphate positional effects observed.

102 genetic segregation, thereby eliminating any positional effects of transgene insertions.

103 ted to increased recovery without detectable positional effects.

104 To explore what features are sufficient for positional encoding, we asked whether arbitrary molecule

105 opulation identified ceruloplasmin (Cp) as a positional eQTL in macrophages but not in serum.

106 as well as external landmarks to correct the positional error that accumulates(8,9).

107 nd velocity perception to construct a future positional estimate of its prey, indicating an ability t

108 ntify 202 loci implicating 956 genes through positional, expression quantitative trait loci, and chro

109 spectral analysis provides insight into the positional extent of disorder and the nature of the ener

110 germline substitution procedure, maintaining positional fidelity using an innovative workaround.

111 This argues for a key role of positional fluctuations in dictating stem cell number an

112 ytometry ("biosorter"), capable of recording positional fluorescence and object granularity informati

113 es' (rare somatic hypermutations, rSHM, with positional frequency of <1%) that resulted in compromise

114 ly attributed to the underlying influence of positional functionalization on the kinetics of cis->tra

115 cine in surgical guidance, in particular the positional guidance of a SPECT/CT-based 3-dimensional im

116 role of nuclear medicine, in particular the positional guidance of a SPECT/CT-based 3D imaging roadm

117 scium genome codes for many of the conserved positional guide proteins used for chromosome segregatio

118 a 48-h window of regeneration, during which positional identities could be disrupted in pola2 mutant

119 developing and postnatal brain have distinct positional identities that dictate the types of neurons

120 similar Hox TFs diverge to induce different positional identities.

121 We found that cortical neurons lose their positional identity and axonal selectivity when mouse fe

122 We found that the maintenance of NSC positional identity in the murine brain requires a mixed

123 Although morphogens initially establish NSC positional identity in the neural tube, it is unclear ho

124 he ends of the anterior-posterior (AP) axis, positional identity is determined by anterior and poster

125 ding map that relates morphogen input to the positional identity of neural progenitors.

126 r into forebrain organoids would specify the positional identity of neural tissue in a distance-depen

127 The molecular mechanisms underlying positional identity of these neural stem cells are poorl

128 indicate that synovial fibroblasts exhibit a positional identity that is regulated by endothelium-der

129 scribe an adult role of Hox genes other than positional identity, and the modulatory role of Hox gene

130 development function as master regulators of positional identity.

131 cells express signaling molecules to promote positional identity.

132 The positional influence of a methoxy substituent in bromoan

133 A strong positional influence of tryptophans exists, with residue

134 nalytical platform for the quantification of positional information ("longitudinal profiling") of C.

135 among a broad range of taxa believed to gain positional information and navigate using the earth's ma

136 elopment, contrasting the prevailing view of positional information being slowly refined across succe

137 it, which prevents the collection of dynamic positional information by traditional optical methods.

138 itiation and exemplifies how spatio-temporal positional information can be used to create rhythmicity

139 position is defined by an extrinsic array of positional information cues.

140 Morphogen gradients provide positional information during development.

141 tem maturation involves the stabilisation of positional information for organogenesis, as well as app

142 ointly coordinate their networks and provide positional information for signalling.

143 cues into the superior colliculus providing positional information for the organization of cortical

144 e the first evidence that they [eels] derive positional information from the Earth's magnetic field"

145 y for contraction, but also as the source of positional information guiding regeneration.

146 he BMP family, is a morphogen that specifies positional information in Drosophila wing precursors.

147 The lack of BCs and positional information in other cells is therefore the m

148 Our results provide evidence that positional information in regenerating tissues is not ha

149 erior developmental blueprint by reading out positional information in the Bicoid morphogen.

150 of biosorter data, however, do not integrate positional information into their analysis and data visu

151 s in regions tested express PCGs, suggesting positional information is a major feature of muscle.

152 Positional information is essential for coordinating the

153 Positional information is fundamental to animal regenera

154 This positional information is often achieved through the act

155 Positional information is required for animal regenerati

156 n of peripheral heterochromatin ensures that positional information is safeguarded through cell divis

157 It remains unclear how essential positional information is transmitted through cell divis

158 This provides a genetic code to define positional information of any ectoderm sample along the

159 at different stages of translation based on positional information of footprints across individual t

160 Moreover, the positional information of the barcode along the template

161 However, how positional information of the missing structure is recal

162 ranscriptional circuit that confers distinct positional information on the two ends of an amputated f

163 tissues, cells decide their fates by sensing positional information provided by specialized morphogen

164 In plants, positional information provided by the hormone auxin reg

165 ng in the embryonic chick wing bud specifies positional information required for the formation of adu

166 The positional information required for tissue patterning is

167 ar auxin transport, but how this impacts the positional information required to establish this tissue

168 During development, cells gain positional information through the interpretation of dyn

169 l transcription factor Bicoid (Bcd) provides positional information to activate target genes at diffe

170 onment, much like signaling molecules convey positional information to organize embryonic tissues.

171 In the map step, an animal derives positional information to select a direction, whereas in

172 l concepts of reaction-diffusion systems and positional information, proposed by Alan Turing and Lewi

173 ated that sites of auxin minima also provide positional information.

174 f broad roles for connective tissue in adult positional information.

175 sue turnover require new cell production and positional information.

176 ause of a BMPs signalling gradient conveying positional information.

177 al processes based on reaction diffusion and positional information.

178 thways for providing cells with temporal and positional information.

179 ring cell fate leads to an adjustment of the positional inheritance of parental nucleosomes that refl

180 tional motif-visualization tools in handling positional interdependencies and utilizing ranked or wei

181 uncovered a correlation between double bond positional isomer abundance and the hormone receptor sta

182 toward ingenamine (3), which is supposedly a positional isomer of 1.

183 repare purified reference materials for each positional isomer of flubromazepam in which the position

184 The new anion is a positional isomer of the recently reported "staggered" s

185 Herein, we demonstrate that positional isomerism can be used as a simple and powerfu

186 -) (2), showing the possibility to find such positional isomerism in Zintl clusters.

187 h lipogenesis, rendering diverse double-bond positional isomers (C=C isomer) of a given unsaturated l

188 e that detects and quantifies phosphopeptide positional isomers from parallel reaction monitoring and

189 These positional isomers might contribute differently to the t

190 e nRPLC is the ability of resolving multiple positional isomers of ADC that are not well-resolved in

191 VPD) for the characterization of double bond positional isomers of charge inverted dication.FA comple

192 Out of six possible positional isomers of dinitrophenol, only 2,4-DNP has be

193 ers-coated capillary, enabling separation of positional isomers of glycated alpha- and beta-chains on

194 ntification of intact proteoforms, including positional isomers of glycated species in a single run.

195 d ion spectroscopy for the identification of positional isomers of hydroxy-atorvastatins, the primary

196 However, the characterization of the positional isomers of interchain cysteine linked ADCs is

197 ctrometry method for the characterization of positional isomers of interchain cysteine linked ADCs.

198 Additionally, characterization data for positional isomers of known designer benzodiazepines are

199 iciencies of 500 000 plates and resolves the positional isomers of monogalactosylated biantennary N-g

200 s (CE), and MALDI-MS were adopted to resolve positional isomers of sialic acids.

201 o the modifier, we have selected a series of positional isomers of sulfonamide drugs that were analyz

202 n mass spectrometry, we firmly confirmed six positional isomers of the MW 212 OSs in PM(2.5) collecte

203 bution of carbon-carbon double bond (C=C db) positional isomers of unsaturated phospholipids (PL) in

204 n leads to multiple substitution degrees and positional isomers within the product.

205 fate groups (3-7), sulfate patterns (sulfate positional isomers), and uronic acid epimerization (epim

206 f multiple quality attributes including DAR, positional isomers, conjugation sites, occupancy, and mi

207 differentiate sn-positional and double-bond-positional isomers, such as the regioisomeric phosphatid

208 ug-to-antibody ratio (DAR) species, and drug positional isomers, which must be monitored to ensure th

209 not readily differentiate between potential positional isomers.

210 eines and generate heterogeneous mixtures of positional isomers.

211 Here, we show that a positional isotopomer NMR tracer analysis (PINTA) method

212 itochondrial oxidation in humans, we applied positional isotopomer NMR tracer analysis (PINTA) to ass

213 uxes and their regulators in humans by using positional isotopomer NMR tracer analysis.

214 vidence that Nell2 acts as a domain-specific positional label in the dLGN that discriminates contrala

215 it is possible to draw their structures with positional labels on paper, with some training.

216 ers to converge around 'hubs' which serve as positional landmarks.

217 ies between mouse gastruloids and embryos in positional lineage segregation and somite formation.

218 ation of glycan isomers differentiating from positional, linkage, branching, and anomeric structures

219 encode divergent proteins and identified the positional locations of amino acid changes in the contex

220 Positional mapping revealed a single critical locus on c

221 sequencing combined, where applicable, with positional mapping.

222 using specially designed DNA molecules with positional markers, we demonstrate that the translocatio

223 ate this distance and compare our results to positional measurements of the alula on spread-wing spec

224 will facilitate future functional studies of positional memory during appendage regeneration.

225 ctors of the successor representation, human positional memory was degraded in a trapezoid environmen

226 Finally, we determined the positional mismatch tolerance of observed spacer-protosp

227 The positional modulation of CA1 neuronal responses has been

228 This positional monofunctionalization strategy was connected

229 al structure, isoelectric point and frequent positional motifs.

230 To understand the dynamics of GQs with positional multiplicity, we studied five and six repeats

231 ) according to two different definitions for positional obstructive sleep apnea (POSA).

232 e and synthetic activity in correlation with positional or spatial cues.

233 In a smectic-A LC, the emergence of positional order at the transition from the nematic phas

234 (COFs) are network polymers with long-range positional order whose properties can be tuned using the

235 al cadherins define at a molecular level the positional organization of motor neuron subtypes into di

236 revealed that the majority of orthologs were positional orthologous genes (POGs) with localization on

237 to form a contiguous matrix, thus creating a positional overlap at the points of fusion between what

238 Auto-scored positional oximetry is a clinically viable alternative t

239 Evaluate the concordance between overall and positional oxygen desaturation indices (ODI) and apnea-h

240 Absence of suboptimal positional parameters was defined as appropriate positio

241 s species, but the precise developmental and positional patterns of expression and gene networks are

242 ydrodynamics (SPH) approach to study various positional placements of the MC in the mitral valve and

243 racterized if uracil incorporations have any positional preference.

244 Here, we compare over 18.8 million positional records of individuals against Greater London

245 utations relies on the assumption that exact positional recurrence is unlikely by chance; thus, the p

246 Without the positional regulation afforded by radial confinement, ch

247 RWOV is based on finding the positional relationship between the most relevant words

248 he properties of chromatin domains and their positional relationships across data sets without a prio

249 riments into network models that reflect the positional relationships among these features on differe

250 the interacting surface interface with rapid positional relaxation associated with similarly directed

251 In IBD, we observe a positional remodelling of goblet cells that coincides wi

252 the presence of an arboreal component in the positional repertoire of Australopithecus.

253 e that enables motif analysis, statistics on positional residue depletion/enrichment, and data analys

254 petting of liquids in 3D space at speeds and positional resolutions required for qPCR.

255 of cocaine, the uncertainty corresponds to a positional RMSD of 0.17 A.

256 The average positional RMSE on the NMR powder structure is <r(av)> =

257 These data demonstrate an instructive positional role for Hofstenia muscle and this similarity

258 m results obtained from a MC3R mixture-based positional scanning campaign.

259 ted the substrate specificity for HGFA using positional scanning of substrate combinatorial libraries

260 ynthesized for the first time a MUC1-derived positional scanning synthetic glycopeptide combinatorial

261 E4 and furin inhibition were investigated by positional scanning using peptide libraries that substit

262 Control of positional selectivity in C-H activation reactions remai

263 Positional selectivity is dictated by a 1,5-hydrogen ato

264 thod features mild reaction conditions, high positional selectivity, and excellent functional-group t

265 rate is an emerging strategy for controlling positional selectivity.

266 advanced measurement capabilities, including positional sensing, biomacromolecular conformation analy

267 is desirable to obtain the photoresponse and positional sensitivity over a much larger area.

268 However, such positional shifts are stochastic and not heritable, cons

269 the functions of which are unclear, undergo positional shifts toward the catalytic center.

270 Our work identified positional signals that activate regionalized transcript

271 his approach neglects to take account of the positional significance of mutations - the function of a

272 MINPPs are not restricted by a strong positional specificity making them attractive targets fo

273 obile lysine residue as a key determinant of positional specificity of the enzyme.

274 Our results demonstrate positional stability of a highly diverged CENH3 on indep

275 Positional stable isotope tracer analysis reveals carbon

276 The positional statistics of a trapped nanoparticle in this

277 provide new evidence in favor of the role of positional strategies in the organization of sensory-mot

278 ts on axo-dendritic interactions, we propose positional strategies that can account for sensory-motor

279 Our study identifies positional strategies with prominent roles in the organi

280 mmetrically moving patterns with and without positional symmetry.

281 ontal or symmetrical motion, with or without positional symmetry.

282 E STATEMENT The mammalian brain implements a positional system with two key pieces: place and grid ce

283 l signals while at the same time maintaining positional targeting.

284 tin is more prevalent in energy storing than positional tendons, and is mainly localised to the IFM.

285 , in young and old equine energy storing and positional tendons.

286 tendons are more elastic and extensible than positional tendons; behaviour provided by specialisation

287 bit a greater response to supine restriction positional therapy.

288 Sleep measurements are obtained from positional tracking of individual animals, and arousal t

289 Variance analysis of the real-time positional trajectories of RNAP after a stall revealed t

290 We propose a method to quantify positional uncertainties in crystal structures determine

291 ypothesis by systematically manipulating the positional uncertainty of saccadic targets.

292 whether perceptual reports show evidence of positional uncertainty, source confusion, and featural a

293 at considers variant type, gene features and positional uncertainty.

294 actual density values of the atoms nor their positional uncertainty.

295 propose that this rapid plasticity keeps the positional update in register with the movement of the r

296 re host autopod, indicating that the autopod positional value is irreversibly determined.

297 nce that Hoxa13 provides an autopod-specific positional value that correctly allocates cells into the

298 An intrinsic timing mechanism specifies the positional values of the zeugopod (i.e. radius/ulna) and

299 es antero-posterior (thumb to little finger) positional values.

300 f velocity accuracy, positional accuracy and positional variability.