ライフサイエンスコーパス: positional information

1 's 'reaction-diffusion' and Lewis Wolpert's 'positional information'.

2 nterior-posterior axis of the embryo provide positional information.

3 e nuclear Bcd concentrations and Bcd-encoded positional information.

4 genitalia must integrate sexual identity and positional information.

5 fluctuations that contribute to the error in positional information.

6 ay an important role in the establishment of positional information.

7 model systematically combining sequence and positional information.

8 each cell type that arises independently of positional information.

9 hat integrates neural and anterior-posterior positional information.

10 , which involves gradual regaining of normal positional information.

11 linkage map that incorporates sequence-based positional information.

12 that thalamic axons indeed use intracortical positional information.

13 ated that sites of auxin minima also provide positional information.

14 switch fate when exposed to a new source of positional information.

15 phase of the cell cycle in response to local positional information.

16 uration, inadequate for the establishment of positional information.

17 f broad roles for connective tissue in adult positional information.

18 or that is suitable for the specification of positional information.

19 s; and that also incorporates sequence-based positional information.

20 sue turnover require new cell production and positional information.

21 neural crest-derived mesenchymal cells with positional information.

22 a central role in generating left-right (LR) positional information.

23 ause of a BMPs signalling gradient conveying positional information.

24 al processes based on reaction diffusion and positional information.

25 cell shape and need not reflect fine-grained positional information.

26 or edges; within A its concentration confers positional information.

27 iorly, suggesting that egl-27 influences A/P positional information.

28 an effort to identify components of maternal positional information.

29 thways for providing cells with temporal and positional information.

30 ique direct mechanism through which to relay positional information.

31 regulatory network predictions based on gene positional information.

32 l identity, consistent with muscle harboring positional information.

33 e, but has been restricted to providing only positional information.

34 the different axes to obtain directional and positional information.

35 g to maximize the accuracy of gradient-based positional information.

36 atially varying concentrations and so encode positional information.

37 how Hox-TALE interactions evolved to provide positional information.

38 leaves provide a unique opportunity to study positional information.

39 low cytometry, while also gathering cellular positional information.

40 ique role for Rargb in conferring left-right positional information.

41 This database provides positional information about human BAC clones from the R

42 Orientational as well as positional information about potential functional groups

43 others act at the time of contact, providing positional information about the appropriateness of targ

44 tissue has been associated with transferring positional information across tissue boundaries.

45 ng the SMC division, and is not specified by positional information acting on daughter cells after co

46 ain protein Hex, an early marker of anterior positional information, acts as a transcriptional repres

47 tervals [-1000, 0], [-500, 0] and [-250, 0], positional information aided motif prediction less and l

48 shed after amputation, a dynamic gradient of positional information along the proximodistal (PD) axis

49 less (Wg) and Decapentaplegic (Dpp) organize positional information along the proximodistal (PD) axis

50 to alter the interpretation of gradients of positional information along the proximodistal axis of t

51 ly requires the generation and perception of positional information along the radial (adaxial versus

52 recruitment zone to reset proximodistal (PD) positional information and assemble the blastema.

53 Thus, positional information and cell motility underlie the di

54 ion may pattern the neural tube, integrating positional information and cell type differentiation.

55 draft genome sequence in providing accurate positional information and detailed characterization of

56 eries the e!Ensembl BioMart server to obtain positional information and discovers homology relations

57 that may underlie these QTL on the basis of positional information and functional arguments.

58 Selection must therefore act on positional information and its apportionment, rather tha

59 among a broad range of taxa believed to gain positional information and navigate using the earth's ma

60 air cells and non-hair cells, in response to positional information and the activity of the homoeodom

61 epend both on patterning genes, which assign positional information, and on genes that regulate mecha

62 ptors and ephrins constitute domain-specific positional information, and the spatially accurate recep

63 suggests that establishing and interpreting positional information are not independent processes in

64 cues on cell fate has shown that domains of positional information are organised with well-defined b

65 s other markers indicates the involvement of positional information as a primary determinant in regen

66 nd instead results from an interplay between positional information assigned during early limb bud de

67 To determine how LR positional information becomes ;translated' into anatomi

68 elopment, contrasting the prevailing view of positional information being slowly refined across succe

69 T protein provides a mechanism for signaling positional information between cell layers of the root.

70 exts, a locally produced morphogen specifies positional information by forming a concentration gradie

71 gen gradients provide embryonic tissues with positional information by inducing target genes at diffe

72 ical view of development, a cell can acquire positional information by reading the local concentratio

73 it, which prevents the collection of dynamic positional information by traditional optical methods.

74 Our studies suggest that positional information can be stored transiently in the

75 Recent results indicate that positional information can be transmitted through interc

76 itiation and exemplifies how spatio-temporal positional information can be used to create rhythmicity

77 ggesting that other developmental cues, like positional information, can progressively over-ride the

78 Here, we study the mechanisms by which positional information conveyed by signaling pathways an

79 lation, cells in both germ layers read their positional information coordinately from a single morpho

80 e associated with loss of ability to express positional information cues that are required for normal

81 position is defined by an extrinsic array of positional information cues.

82 the first example of a system that generates positional information de novo.

83 Positional information derived from local morphogen conc

84 tein patterns are established, and how their positional information directs downstream processes.

85 entration gradient appropriate for conveying positional information during cortical axon guidance in

86 Morphogen gradients provide positional information during development.

87 One way in which cells acquire positional information during embryonic development is b

88 ion in which cellular activity feeds back on positional information encoded by gradients, analogous t

89 esponsible for the initial interpretation of positional information encoded by maternal gradients.

90 ms, but it also relies on the structural and positional information encoded in extracellular matrices

91 nd Ds expression provide partially redundant positional information essential for specifying the pola

92 An important unresolved question is how positional information established by these morphogen gr

93 Concurrently, positional information established principally by the ve

94 with there being a gradient of Bmp-dependent positional information extending throughout the entire n

95 We identified a gene, pom1, that provides positional information for both growth and division in S

96 opment to directly shape tissues, to provide positional information for cell fate decisions and to en

97 n addition, we show the capability to obtain positional information for modifications such as trimeth

98 rces is a novel perspective on the source of positional information for neuronal specification in the

99 tem maturation involves the stabilisation of positional information for organogenesis, as well as app

100 photoreceptor axon target fields and provide positional information for photoreceptor axon guidance.

101 e detection relies on accurate annotation of positional information for polyA tails added posttranscr

102 ointly coordinate their networks and provide positional information for signalling.

103 The use of the MinD/ParA family to provide positional information for spatial organization continue

104 n follicle cells, which provide dorsoventral positional information for the embryo.

105 ressions of Eph-ephrins are known to provide positional information for the formation of topographic

106 ion, and nucleoid occlusion, indicating that positional information for the future pole is independen

107 cues into the superior colliculus providing positional information for the organization of cortical

108 identify a protein, PodJ, that provides the positional information for the polar localization of bot

109 control of regulatory elements that provide positional information for the regional specification of

110 d from the 3' end to provide high-resolution positional information for the RNA polymerases.

111 embryo, but exactly how these factors act as positional information for this patterning is not yet fu

112 organizes protein similarity and genetic map positional information from diverse sources in the publi

113 In Drosophila, positional information from genes important in anteropos

114 Coupling this information with positional information from high throughput mapping prog

115 ) signaling proteins are thought to transmit positional information from surface guidance cues to the

116 The incorporated positional information from the alignments and PE reads

117 expression provide spatial signals that link positional information from the anterior-posterior patte

118 e the first evidence that they [eels] derive positional information from the Earth's magnetic field"

119 To test the hypothesis that lobsters derive positional information from the Earth's magnetic field,

120 ion and, consistent with a role in conveying positional information from the egg chamber to the embry

121 n the vertebrate embryo requires transfer of positional information from the node to the periphery, r

122 activities is essential for transfer of L-R positional information from the node.

123 into muscular and non-muscular tissue using positional information from the surrounding tissue.

124 In addition, sea turtles derive positional information from two magnetic elements (incli

125 he Drosophila embryo requires extraembryonic positional information generated during oogenesis.

126 stem of extracellular proteins to generate a positional information gradient.

127 We discuss how such general relativistic positional information (GRPI) can guide systems-level ap

128 y for contraction, but also as the source of positional information guiding regeneration.

129 In planarians, positional information has been identified from study of

130 In the regenerating amphibian limb, positional information has traditionally been considered

131 anscription factors play a role in providing positional information important for topographic mapping

132 How morphogens convey positional information in a developing embryo, when sign

133 noise, allows the pom1p gradient to specify positional information in a robust manner.

134 he BMP family, is a morphogen that specifies positional information in Drosophila wing precursors.

135 by MinE underlies the dynamic processing of positional information in E. coli to identify precisely

136 rinciples similar to those used to establish positional information in embryonic patterning are also

137 Homeobox genes convey positional information in embryos and their role in patt

138 This process, utilizing positional information in existing tissue at unpredictab

139 cell morphogenesis and the establishment of positional information in fission yeast.

140 n accuracy suggests that ChloroP uses little positional information in its decision-making; an unexpe

141 present evidence that kni and knrl link A/P positional information in larval wing imaginal discs to

142 ntribute to pattern formation by determining positional information in morphogenetic fields.

143 The lack of BCs and positional information in other cells is therefore the m

144 Our results provide evidence that positional information in regenerating tissues is not ha

145 e to patch-clamp studies, the maintenance of positional information in single-channel measurements, r

146 dissect the molecular mechanisms conferring positional information in skeletal muscles, we character

147 Previous studies have demonstrated roles for positional information in specification of daughter cell

148 Pax2 protein, demonstrating that it receives positional information in the absence of a developing pr

149 erior developmental blueprint by reading out positional information in the Bicoid morphogen.

150 asymmetry can be explained by differences in positional information in the body column tissue that ev

151 n of these proteins implies the existence of positional information in the cell, but how this informa

152 istinct cortical signaling centers establish positional information in the cortical primordium and re

153 r tyrosine kinases and their ligands provide positional information in the developing visual system.

154 Positional information in the dorsoventral axis of the D

155 ich responds in a unique way to gradients of positional information in the early Drosophila embryo.

156 rganization of the larval disc originates as positional information in the embryo, thus providing a c

157 PHAVOLUTA genes in the perception of radial positional information in the leaf primordium.

158 r candidate regulators of anterior-posterior positional information in the limb bud, including HoxB8

159 s suggest that GATA3 expression may maintain positional information in the maculae during sensory reg

160 cold-perceived gravistimulation by providing positional information in the pulvini prior to the redis

161 ling cascade that establishes dorsal-ventral positional information in the retina and controls the fo

162 us deletions (HODs), have provided important positional information in the search for cancer-causing

163 reasing efficiency with which observers used positional information in the stimulus.

164 im1-independent role in the establishment of positional information in the trunk.

165 n cardiac organogenesis, growth control, and positional information, including the direction of cardi

166 matrix and chemokine provides the necessary positional information independent of a soluble spatial

167 How positional information instructs adult tissue maintenanc

168 hat the anatomical locus at which motion and positional information interact is area V5/MT rather tha

169 ffusion and gene expression regulation shape positional information into an appropriate profile with

170 how groups of cells recognize and translate positional information into morphogenetic movement remai

171 of biosorter data, however, do not integrate positional information into their analysis and data visu

172 s in regions tested express PCGs, suggesting positional information is a major feature of muscle.

173 As multicellular organisms grow, positional information is continually needed to regulate

174 Positional information is crucial for regeneration, but

175 Positional information is essential for coordinating the

176 Positional information is fundamental to animal regenera

177 dd to a growing body of evidence that radial positional information is important in meristem formatio

178 ression of Xtmyf-5 expression, implying that positional information is integrated at this site.

179 In addition, positional information is integrated with temporal cues

180 in contributing to heart formation, but how positional information is integrated with this pathway t

181 In the nevermind (nev) mutant, D-V positional information is not maintained by dorsonasal r

182 This positional information is often achieved through the act

183 Positional information is pivotal for establishing devel

184 nt evidence that, in Escherichia coli, polar positional information is present at midcell independent

185 Throughout mitosis the PPBs positional information is preserved by factors that cont

186 This positional information is relayed in the extracellular s

187 Positional information is required for animal regenerati

188 n of peripheral heterochromatin ensures that positional information is safeguarded through cell divis

189 bryo variability, but that this noise in the positional information is strongly decreased ('filtered'

190 Interpretation of positional information is thought to rely on direct, con

191 It remains unclear how essential positional information is transmitted through cell divis

192 No positional information is used in the count, but it has

193 s suggest that the ability of MinCD to sense positional information is utilized during sporulation to

194 hat has remained unanswered is how does this positional information lead to the correct spatial activ

195 nalytical platform for the quantification of positional information ("longitudinal profiling") of C.

196 ggesting that IcsA recognition of this polar positional information may influence cell division.

197 rams for identifying sequence motifs exploit positional information, most of them model it only impli

198 f stomata and bulliform cells, implying that positional information must direct the differentiation p

199 oc locus to mouse chromosome 16 provides the positional information necessary to identify the candida

200 The Hox genes cooperate in providing positional information needed for spatial and temporal p

201 endent regenerative response indicative of a positional information network.

202 We have exploited the positional information obtained from SPFI to develop a m

203 This provides a genetic code to define positional information of any ectoderm sample along the

204 at different stages of translation based on positional information of footprints across individual t

205 evelopment in detail, including temporal and positional information of organ initiation.

206 Moreover, the positional information of the barcode along the template

207 However, how positional information of the missing structure is recal

208 ivision zone, translating and preserving the positional information of the PPB by maintaining downstr

209 Positional information of this gradient is transmitted t

210 he proprioceptive system provides continuous positional information on the limbs and body to the thal

211 ranscriptional circuit that confers distinct positional information on the two ends of an amputated f

212 ronal G alpha(s) pathway transduces critical positional information onto the core G alpha(q) pathway

213 By removing positional information, our simpler methods allow us to

214 AX pathway modulates TKV signaling to create positional information over the embryonic ectoderm.

215 l concepts of reaction-diffusion systems and positional information, proposed by Alan Turing and Lewi

216 c and normal blastemas, and the diversity of positional information provided by blastema cells derive

217 epidermal patterning relies in many cases on positional information provided by cell-cell communicati

218 not known how progenitor cells interpret the positional information provided by inducing signals or h

219 During development of the early neural tube, positional information provided by signaling gradients i

220 tissues, cells decide their fates by sensing positional information provided by specialized morphogen

221 In plants, positional information provided by the hormone auxin reg

222 d within the developing kidney, and that any positional information provided by the mesenchymal expre

223 Our results demonstrate that the positional information provided by the wt Bcd gradient p

224 roposes that epidermal patterning depends on positional information rather than lineage relationships

225 We propose that the positional information received by a cell at a particula

226 These findings indicate that polar positional information recognized by IcsA depends on one

227 Escherichia coli, the establishment of polar positional information recognized by IcsA requires the a

228 thways for polar cell envelope synthesis and positional information recognized by polar proteins.

229 ions suggest the intriguing possibility that positional information regulates convergence and extensi

230 We also provide evidence that positional information regulating Fat action is provided

231 pattern is defined during embryogenesis and positional information remains active in the root until

232 However, the nature and the origin of positional information remains elusive.

233 n factors expressed in gut mesenchyme convey positional information required for anterior-posterior p

234 e continuous generation or interpretation of positional information required for epidermal specificat

235 The positional information required for such migratory behav

236 ng in the embryonic chick wing bud specifies positional information required for the formation of adu

237 m, some of these genes are likely to control positional information required for the sagittal organiz

238 The positional information required for tissue patterning is

239 ar auxin transport, but how this impacts the positional information required to establish this tissue

240 To understand the true source of the positional information responsible for limiting Tbx2, Tb

241 Based on this positional information, roughly one-third of the genes a

242 A rigorous statistical analysis showed that positional information significantly improved the predic

243 tissue turnover, providing a model for adult positional information studies.

244 ogress zone) undergo a progressive change in positional information such that their specification is

245 nctions, act more globally to provide graded positional information that can be interpreted by respon

246 ogenic precursor cells must be responding to positional information that controls nephrogenic fate.

247 nstrate that homeotic selector genes provide positional information that determines the anteroposteri

248 haps via diffusion, to yield the gradient of positional information that determines the embryonic dor

249 ete sites that are specified by pre-existing positional information that governs the development of w

250 an epithelium, tricellular junctions encode positional information that helps orient mitotic spindle

251 of activity gradients of BMP, which provide positional information that influences cell fates.

252 pecification in the root epidermis relies on positional information that is organised in stable domai

253 st their functions by interpreting the local positional information that is programmed into the RPC l

254 The nature of the positional information that leads to the proper localiza

255 ical Wnt, and retinoic acid signals generate positional information that leads to the restricted expr

256 ed signals, known as morphogens, provide the positional information that organizes gene expression an

257 suggest that LGN participates in setting up positional information through a signaling cascade.

258 During development, cells gain positional information through the interpretation of dyn

259 nar polarity in the eye: first in setting up positional information through the production of a plana

260 we propose that the Dorsal gradient supplies positional information throughout nuclear cycles 10-14,

261 nteraction between Otx2 and Gbx2 establishes positional information thus providing a general mechanis

262 l transcription factor Bicoid (Bcd) provides positional information to activate target genes at diffe

263 Morphogen gradients, which provide positional information to cells in a developing tissue,

264 We used positional information to clone IAR1, which encodes a no

265 We used positional information to determine that one ibr5 suppre

266 We used positional information to determine that the gene defect

267 , they provide a novel mechanism linking Hox positional information to differences in neuronal archit

268 med-pbx functions as a central integrator of positional information to drive patterning of regenerati

269 s proceeds via the correct interpretation of positional information to establish boundaries that sepa

270 tinal determination gene expression to relay positional information to eye target genes, because the

271 y important that signaling gradients provide positional information to govern morphogenesis of multic

272 he extracellular matrix (ECM) provides local positional information to guide motoneuron axons toward

273 fibroblasts and highlights the importance of positional information to instruct pattern formation dur

274 proteins and the bacterial nucleoid provide positional information to negatively regulate cytokinesi

275 f sprouts, a location suitable for conveying positional information to neighboring ECs.

276 this mechanism may provide both A-P and D-V positional information to neuronal precursors located wi

277 onment, much like signaling molecules convey positional information to organize embryonic tissues.

278 ic gap gene expression, which in turn convey positional information to pair-rule and segment-polarity

279 gen gradient, has been hypothesized to carry positional information to pattern tissues.

280 ecture is not a default state but depends on positional information to precisely coordinate patterns

281 center that utilizes an existing network of positional information to regulate patterning during ske

282 In the map step, an animal derives positional information to select a direction, whereas in

283 ne membrane, provides structural support and positional information to the embryo.

284 m the pre-patterned ectoderm, which provides positional information to the underlying cardiac mesoder

285 imo-distally oriented subdomains that convey positional information to these developing tissues.

286 Correct radial patterning depends on the positional information transmitted through limited SHR i

287 mbrane protein localization data by deriving positional information via surface fitting and combining

288 hese expression levels thus form a code for "positional information." We show how to measure this inf

289 A-GLAM's predictions with and without positional information were compared on two human TFBS d

290 remain biophysically interpretable and hold positional information where experiment and model disagr

291 anar environments, place cells provide focal positional information, whereas grid cells supply odomet

292 Bacteria specify positional information, which determines where cell divi

293 osing the ctenophore adult body plan possess positional information, which is utilized to reconstruct

294 n the absence of differentiation signals use positional information, while cells that divide late aft

295 The integration of positional information with gene expression data allowed

296 nd non-hair cells is dependent on domains of positional information with strict boundaries.

297 membrane and small GTPases as integrators of positional information with the activities of the domain

298 membrane skeleton behaves as a transducer of positional information within cells.

299 ng lbl1, rld1 and the yabby genes integrates positional information within the SAM, and leads to adax

300 Morphogen gradients provide embryos with positional information, yet how they form is not underst