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1 es at extrasynaptic sites (>0.5 mum from the postsynaptic density).
2 in that anchors receptors and enzymes at the postsynaptic density).
3 for coupling AMPAR endocytic zones with the postsynaptic density.
4 ctivity-dependent accumulation of tau in the postsynaptic density.
5 alpha is present in a mobile fraction of the postsynaptic density.
6 undergo constant cycling into and out of the postsynaptic density.
7 are a family of scaffolding proteins of the postsynaptic density.
8 major scaffolding protein of the excitatory postsynaptic density.
9 nclude modulation of receptor trafficking to postsynaptic density.
10 tructural protein found predominantly at the postsynaptic density.
11 eceptors and scaffolding proteins within the postsynaptic density.
12 single presynaptic active zone and a single postsynaptic density.
13 stering of glutamate receptors (GLUR) at the postsynaptic density.
14 otentially compensatory expansion of AZs and postsynaptic densities.
15 ma membrane and in dendritic spines close to postsynaptic densities.
16 re less rigidly organized than glutamatergic postsynaptic densities.
17 plasma membranes, close to, but not within, postsynaptic densities.
18 xchange factor that is localized in neuronal postsynaptic densities.
19 concentration of synaptic vesicles near the postsynaptic densities.
20 ntaining small, round vesicles and prominent postsynaptic densities.
21 regulation of mGluR1 in 5-HT(2A)R-containing postsynaptic densities.
22 matrix and increased the size of excitatory postsynaptic densities.
23 ation and experience-dependent regulation of postsynaptic densities.
29 f neuronal nitric oxide synthase (nNOS) from postsynaptic density 95 (PSD95) and a reduced production
30 ation, and protein/protein interactions (eg, postsynaptic density 95 (PSD95)), may drive the predispo
31 ls concomitant with higher levels of 5-HT2CR:postsynaptic density 95 complex distinguished HI rats fr
33 iPS-NPCs increased expression of synapsin-1, postsynaptic density 95, brain derived neurotrophic fact
35 teracts with proteins through its three PDZ (postsynaptic density 95, discs large, zonula occludens-1
36 utamate transporter 1-positive (VGlut1+) and postsynaptic density 95-positive (PSD95+) puncta, on PV
38 tory factor-1 (NHERF1) is a cytoplasmic PDZ (postsynaptic density 95/disc large/zona occludens) prote
39 gion specifically interacted with the NHERF1 postsynaptic density 95/disc-large/zona occludens-1 doma
40 w that the expression of GRIP1, a multi-PDZ (postsynaptic density 95/discs large/zona occludens) doma
41 nteraction modules in mammalian cells is the postsynaptic density 95/discs large/zonula occludens 1 (
44 ulatory protein (E3KARP) both consist of two postsynaptic density 95/disks large/zona occludens-1 (PD
45 d presynaptic (Synapsin-1) and postsynaptic (postsynaptic density 95; PSD-95) staining, diffuse demye
46 thyl-d-aspartate receptor subunit 2B (NR2B), postsynaptic density-95 (PSD-95) and microtubule-associa
47 an age-related increase in the ratio of both postsynaptic density-95 (PSD-95) and the GluN2A subunit
49 se hippocampal organotypic slice cultures, a postsynaptic density-95 (PSD-95) knock-out mouse line an
50 te (NMDA) neurotransmitter receptors and the postsynaptic density-95 (PSD-95) membrane-associated gua
51 entries into spines regulate the increase in postsynaptic density-95 (PSD-95) protein after brain-der
53 ely 65%) of LDLR and LRP1 is associated with postsynaptic density-95 (PSD-95)-positive synaptosomes,
54 ies on intracellular calcium signaling, PDZ [postsynaptic density-95 (PSD-95)/Discs large (Dlg)/zona
57 ressed increase in other proteins, including postsynaptic density-95 and alpha-calcium/calmodulin-dep
59 Translational induction of an FMRP target, postsynaptic density-95 mRNA, required both PP2A and UPS
60 is provided by the scaffold protein PSD-95 (postsynaptic density-95), which is associated with alpha
61 peptide (KV1-C peptide) corresponding to the postsynaptic density-95, discs large, zonula occludens-1
63 The EAAT2b cytoplasmic C terminus contains a postsynaptic density-95/Discs large/zona occludens-1 (PD
65 interaction between SAP102 and NR2B is PDZ (postsynaptic density-95/Discs large/zona occludens-1) do
66 P-REX2 provides high-affinity binding to the postsynaptic density-95/Discs large/zona occludens-1-bin
67 occur through a direct interaction with the postsynaptic density-95/discs large/zonula occludens-1-a
68 that are symmetric (in that there is little postsynaptic density), a characteristic of inhibitory sy
69 labeled endings in the DCN formed asymmetric postsynaptic densities, a feature of excitatory neurotra
70 ical slices and blocks Pyk2 translocation to postsynaptic densities, a key step required for Pyk2 act
71 c changes as shown by an increased length of postsynaptic density, accompanied by an increased expres
73 the major scaffolding protein at excitatory postsynaptic densities and a potent regulator of synapti
74 ve more stubby spine structures with smaller postsynaptic densities and an increase in the frequency
75 nt tau depleted PSD-95, resulting in smaller postsynaptic densities and impaired synaptic localizatio
76 gulation impedes focal GluN1 distribution at postsynaptic densities and impairs synaptic function in
77 e, BC1 KO mice have enlarged spine heads and postsynaptic densities and increased synaptic levels of
78 abundance of the GluN2B subunit of NMDAR in postsynaptic densities and NMDAR-dependent long-term pot
80 allows for the concomitant remodeling of the postsynaptic density and actin spinoskeleton and for the
81 iary subunits, SynDIG4 is de-enriched at the postsynaptic density and colocalizes with extrasynaptic
82 flow-cytometry analysis, down-regulation of postsynaptic density and dendrite spine morphology regul
85 kinases (MAGUKs) are major components of the postsynaptic density and play important roles in synapti
86 geted mass spectrometry was used to quantify postsynaptic density and voltage-gated calcium channel p
88 , synaptic vesicles, spines, spine apparati, postsynaptic densities, and mitochondria) are rendered a
89 ptic terminals, labelling both dendrites and postsynaptic densities, and simultaneously labelling a r
90 dly, SynCAM 1 can form ensembles proximal to postsynaptic densities, and synapses containing these en
91 illed cells, ultrastructural analysis of the postsynaptic density, and electrophysiological recording
92 ed, including the subsynaptic reticulum, the postsynaptic density, and the glutamate receptor cluster
93 to cell bodies and dendrites, including the postsynaptic density, and within the last 5 years severa
94 ors receptors and signaling molecules to the postsynaptic density-and are regulated by the phosphoryl
96 number of release sites, active zone length, postsynaptic density area and number of vesicles in the
97 resynaptic AZ number per bouton area and the postsynaptic density area are both increased in dnlg2 mu
98 d spines had larger synapses, as measured by postsynaptic density area, than single-labeled and unlab
99 ynapses in M1 were larger than in S1 (median postsynaptic density areas of 0.064 mum(2) vs 0.042 mum(
100 res of neurons, such as dendritic spines and postsynaptic density areas, in addition to its distribut
101 lices to 1 nM E2 increases the percentage of postsynaptic densities associated with high levels of im
102 one of the main scaffolding proteins of the postsynaptic density at GABAergic synapses, to monitor t
103 de novo mutations in genes belonging to the postsynaptic density at glutamatergic synapses, particul
105 s are adjacent synaptic regions that share a postsynaptic density, but nascent zones lack the presyna
106 ), a K63-specific deubiquitinase enriched in postsynaptic densities, cleaves K63-chains from PSD-95.
109 including reduced mGlu5 association with the postsynaptic density, enhanced constitutive mGlu5 signal
110 id expansion of the synaptic active zone and postsynaptic density, enhanced dendritic spine plasticit
111 calization of mGluR5 to both synaptosome and postsynaptic density-enriched fractions in the hippocamp
113 nt manner to facilitate its translocation to postsynaptic densities for synaptic tagging and maintena
114 tron microscope imaging demonstrated reduced postsynaptic density formation and fewer dendritic polyr
115 iated defects in dendritic spine morphology, postsynaptic density formation, de novo protein synthesi
116 subunits (GluA1/2/3/4) in homogenates and in postsynaptic density fractions from spinal cord dorsal h
117 was detected in the cytoplasm, membrane and postsynaptic density fractions of neurons, with reduced
118 is to identify changes in the composition of postsynaptic densities from GluN2B(-/-) mouse primary ne
120 nt mono-ubiquitination, compartmentalized at postsynaptic densities, gates retrograde signaling and p
124 tric disorders, has a regulatory role in the postsynaptic density in association with the NMDA-type g
125 esponses and GluA1 levels in the hippocampal postsynaptic density in wild-type and GluA1-S845A mutant
126 rgest CNVs (>500 kb) in genes present in the postsynaptic density, in genomic regions implicated via
127 sis by positioning the endocytic zone at the postsynaptic density, independently of mitochondrial div
128 ssing PSD-95, a major scaffolding protein of postsynaptic density involved in synapse formation, syna
130 95, a principal scaffolding component of the postsynaptic density, is targeted to synapses by palmito
133 nsmitter release, number of docked vesicles, postsynaptic density length, and expression of plasticit
135 plasticity by orchestrating the assembly of postsynaptic density macromolecular signalling complex.
136 proteins are major scaffold proteins of the postsynaptic density; mutations in the human SHANK3 gene
138 e A (PKA), PKC, and calcineurin (CaN) to the postsynaptic densities of neurons, but its role in inhib
139 ty was not influenced by Nogo-A, the size of postsynaptic densities of PF-PC synapses was negatively
140 oltage-sensitive calcium ion channels at the postsynaptic density of a dendritic spine is investigate
142 intense synaptic activity drives tau to the postsynaptic density of excitatory synapses and that Abe
148 the content of the beta3 integrin subunit in postsynaptic density of the accumbens core at 24 h after
149 1-S845 and GluA1 levels in their hippocampal postsynaptic density on the third day of acquisition, wh
151 mmunocytochemistry, electron microscopy, and postsynaptic density preparation that LRP1 is located po
152 dentate hilus, and significant increases in postsynaptic density protein (PSD-95) were found along d
153 ifs with their interacting proteins, such as postsynaptic density protein (PSD95), Drosophila disc la
154 s were measured in the nucleus accumbens for postsynaptic density protein 95 (PSD-95) and SAP90/PSD-9
155 hat SR interacts with the synaptic proteins, postsynaptic density protein 95 (PSD-95) and stargazin,
156 ate (NMDA) receptor and its interaction with postsynaptic density protein 95 (PSD-95) at the synapse
157 mals and cultured slices, and an increase in postsynaptic density protein 95 (PSD-95) by overexpressi
159 72, whereas the synaptic scaffolding protein postsynaptic density protein 95 (PSD-95) stabilizes the
160 troporation of DsRedExpress- and eGFP-tagged postsynaptic density protein 95 (PSD-95) to investigate
162 egradation of the synaptic scaffold protein, postsynaptic density protein 95 (PSD-95), a process that
170 cal imaging of neurons expressing DsRed2 and postsynaptic density protein 95 fused to green fluoresce
172 on of GluN2A and GluN2B subunits, as well as postsynaptic density protein 95 in the rat hippocampus.
173 active, expanded allele (EX-Xa) have reduced postsynaptic density protein 95 protein expression, redu
174 found that the postsynaptic scaffold PSD-95 (postsynaptic density protein 95) undergoes K63 polyubiqu
176 s in spine density and levels of synapsin-1, postsynaptic density protein 95, and glutamate receptor
177 and levels of synaptic proteins synapsin-1, postsynaptic density protein 95, and glutamate receptor
178 ate a role for synaptic proteins synapsin-1, postsynaptic density protein 95, and glutamate receptor
179 es revealed increases in the brain levels of postsynaptic density protein 95, gephyrin, synaptophysin
180 av-1 and membrane/lipid raft localization of postsynaptic density protein 95, NMDA receptor, and trop
181 which targets the synaptic scaffold protein, postsynaptic density protein 95, to enhance downstream s
183 impairments in synapse-associated protein 90/postsynaptic density protein 95-associated protein 3 (SA
184 transporter 1-positive [VGlut1+] puncta and postsynaptic density protein 95-positive [PSD95+] puncta
186 Selective disruption of interactions with postsynaptic density protein 95/disks large/zonula occlu
187 ynapse-associated protein of 97 kilodaltons; postsynaptic density protein of 93 kilodaltons; synapse-
188 ct matches that of the prototypical scaffold postsynaptic density protein of 95 kDa (PSD-95) identify
190 membrane-associated guanylate-like kinases [postsynaptic density protein of 95 kilodaltons; synapse-
193 At this time, levels of GluN2A, GluN2B and postsynaptic density protein PSD-95 were all increased.
196 MRP) regulates expression of the scaffolding postsynaptic density protein PSD95, but the mode of cont
197 ies showed that rat OATP1A1 (rOATP1A1) has a postsynaptic density protein, drosophila disc large tumo
203 in postsynaptic structures can interact with postsynaptic density protein-95 (PSD-95), a key scaffold
204 complex of the synaptic scaffolding protein postsynaptic density protein-95 (PSD-95), neuronal nitri
205 re immunopositive for glutamate receptor and postsynaptic density proteins (viz., GluR1, GluR4, NR1,
206 of Ptchd1-interacting proteins that include postsynaptic density proteins and the retromer complex,
207 he synapse and interacts with multiple known postsynaptic density proteins including the scaffolding
208 s encoding AMPA-type glutamate receptors and postsynaptic density proteins were less edited, whereas
209 s on live neurons were labeled with sQDs and postsynaptic density proteins were visualized with super
211 naling cascades that converge onto GABAergic postsynaptic density proteins, we performed MS analysis
212 renia with the exception of a small group of postsynaptic density proteins, whose co-expression incre
213 or genes encoding members of mouse and human postsynaptic density proteomes (odds ratio 4.56, P = 5.0
214 nstrained genes and for genes located to the postsynaptic density (PSD) (all Bonferroni corrected p <
215 major scaffolding protein in the excitatory postsynaptic density (PSD) and a potent regulator of syn
216 ucing IKK kinase complex is localized at the postsynaptic density (PSD) and activated under basal con
217 conditioned inhibition groups, the ratio of postsynaptic density (PSD) area to docked vesicles at sy
218 ence point to glutamatergic signaling in the postsynaptic density (PSD) as a pathophysiologic mechani
219 term depression (LTD), and a thinning of the postsynaptic density (PSD) at hippocampal synapses.
220 n SGNs to drive differentiation of the large postsynaptic density (PSD) characteristic of the ribbon
222 ositioning of glutamate receptors within the postsynaptic density (PSD) determine excitatory synaptic
223 in (GAP) found in high concentrations in the postsynaptic density (PSD) fraction from the mammalian f
224 .2 L-type Ca(2+) channel mRNA and protein in postsynaptic density (PSD) fractions of the hippocampus,
226 ty of synapses, immunolabeled for either the postsynaptic density (PSD) marker PSD95 or the presynapt
227 SK2-containing channels are expressed in the postsynaptic density (PSD) of dendritic spines on mouse
228 organize an extensive protein complex at the postsynaptic density (PSD) of excitatory glutamatergic s
233 ASD risk genes and genes encoding inhibitory postsynaptic density (PSD) proteins, but not for genes i
234 ses overall synapse proteome complexity, the postsynaptic density (PSD) proteome of zebrafish has low
236 that PSD-95, a major scaffold protein of the postsynaptic density (PSD) that promotes synaptic streng
238 finement in the synapse, and trapping at the postsynaptic density (PSD) through reversible interactio
239 g, and receptor molecules concentrate at the postsynaptic density (PSD) to regulate synaptic strength
240 ribution patterns of the two isoforms at the postsynaptic density (PSD) under basal and excitatory co
242 K-801 binding and NMDA receptor complexes in postsynaptic density (PSD) were in fact increased in sch
243 nd GEFs have been shown to be present at the postsynaptic density (PSD) within excitatory glutamaterg
244 fects in spine morphogenesis along with thin postsynaptic density (PSD), and reduced synaptic transmi
245 in transiently decreased GluA1 levels at the postsynaptic density (PSD), but did not affect extrasyna
246 sion by establishing the architecture of the postsynaptic density (PSD), but the small size of the sy
247 CAMK2 in the structural organization of the postsynaptic density (PSD), deletion of both CAMK2 isofo
249 nucleotide exchange factor localized to the postsynaptic density (PSD), modulates dendritic spine mo
250 fic reduction of dendritic spine density and postsynaptic density (PSD)-95 and spinophilin-positive c
263 neck) and the "distal" half (containing the postsynaptic density [PSD]), whereas after delayed fixat
264 bons in retinal cone bipolar cells (BCs) and postsynaptic densities (PSD95-FP) of retinal ganglion ce
265 uter and inner stratifying dendrites express postsynaptic density (PSD95) immunoreactive puncta sugge
266 huntingtin (HTT), ADAM10 accumulates at the postsynaptic densities (PSDs) and causes excessive cleav
269 protein (GAP) that is a major constituent of postsynaptic densities (PSDs) from mammalian forebrain.
270 ed within natural protein aggregates such as postsynaptic densities (PSDs) in excitatory synapses and
271 n kinase II (CaMKII) is a major component of postsynaptic densities (PSDs) involved in synaptic regul
272 ependent modifications in the composition of postsynaptic densities (PSDs) isolated from rat primary
273 l surface-expression of EphA7 essentially in postsynaptic densities (PSDs) of dendritic spines and sh
274 in and metalloproteinase that resides in the postsynaptic densities (PSDs) of excitatory synapses, ha
275 alysis of membranes associated with isolated postsynaptic densities (PSDs) suggests the PSD-associate
276 PSD95 and SAP97 conformation in vitro and in postsynaptic densities (PSDs) using FRET and EM, and exa
277 sed PSD95-eGFP mice, to visualise excitatory postsynaptic densities (PSDs) using high-resolution and
278 the plasma membrane and is found at neuronal postsynaptic densities (PSDs), but the role of MyoVa in
279 ndrites in each individual neuron, except at postsynaptic densities (PSDs), where it is typically hig
282 urrent study investigated the expression and postsynaptic density redistribution of glutamate recepto
283 igin-1 (NL1), which is located at excitatory postsynaptic densities, regulates activity-dependent syn
286 ton-associated scaffold protein (ARC) of the postsynaptic density, sets previously implicated by geno
289 us synapses in layers 2-3 of LPFC had larger postsynaptic density surface areas and a higher proporti
290 m the smooth endoplasmic reticulum) near the postsynaptic density to promote the persistent firing ne
293 mination of the majority of spines; however, postsynaptic densities were preserved on dendritic shaft
294 Reduced membrane excitability and loss of postsynaptic densities were some of the inaugural events
295 length, spine diameter, and the area of the postsynaptic density were measured from the 3D reconstru
296 e II (CaMKII) forms a major component of the postsynaptic density where its functions in synaptic pla
297 these genes: 1) they localized to the human postsynaptic density, which is crucial for neuronal func
298 mity to synaptic contacts (<0.5 mum from the postsynaptic density), while 27% were distributed along
299 ains of axon terminals, and subjacent to the postsynaptic density within the subsynaptic domains of d
300 guingly suggests that SR may be found at the postsynaptic density, yet the functional implications of