ライフサイエンスコーパス: postsynaptically

1 ripheral nervous system, presynaptically and postsynaptically.

2 I mGluR-LTD appears to be expressed entirely postsynaptically.

3 e zone domains remains intact, both pre- and postsynaptically.

4 dulation can occur either presynaptically or postsynaptically.

5 ynaptically at PF synapses, LTD is expressed postsynaptically.

6 s that not all NMDA-dependent LTP is induced postsynaptically.

7 alpha is localized at synapses both pre- and postsynaptically.

8 citability of central synapses both pre- and postsynaptically.

9 that the block of synaptic responses occurs postsynaptically.

10 ynapse and that it is required both pre- and postsynaptically.

11 at this type of LTD is most likely expressed postsynaptically.

12 ing average frequency are presented pre- and postsynaptically.

13 ACh quanta summate linearly postsynaptically.

14 rns emerge presynaptically and are reflected postsynaptically.

15 ion channels and transporters both pre- and postsynaptically.

16 that sensitivity to convulsions is mediated postsynaptically.

17 ase inhibitor, did not block the NT-3 effect postsynaptically.

18 sticity is thought to be primarily generated postsynaptically.

19 that ended on type II cells pre- as well as postsynaptically.

20 s, and (3) alpha 2AAR operates both pre- and postsynaptically.

21 synaptic clefts, and simpler secondary folds postsynaptically.

22 ilar neurons and granule cells both pre- and postsynaptically.

23 ciated with glutamatergic terminals pre- and postsynaptically.

24 ceptors are located both presynaptically and postsynaptically.

25 ed enhancement of excitability both pre- and postsynaptically.

26 tion and variance, suggesting that CGRP acts postsynaptically.

27 hair cells where it may be localized pre- or postsynaptically.

28 tic density preparation that LRP1 is located postsynaptically.

29 ht-gated mammalian iGluR6 (LiGluR) expressed postsynaptically.

30 pontaneous neurotransmitter release detected postsynaptically.

31 lize to synapses in CA1 and are concentrated postsynaptically.

32 naptically, but are thought to be excitatory postsynaptically.

33 tor presynaptically and a negative regulator postsynaptically.

34 napses, is PICK1 dependent, and is expressed postsynaptically.

35 protein is present both presynaptically and postsynaptically.

36 unction in the endocytosis of AMPA receptors postsynaptically.

37 ity of quantal amplitudes determined pre- or postsynaptically?

38 gic and glutamatergic synapses both pre- and postsynaptically; 2) Pcdh-gammaC5 is also extrasynaptica

39 to postnatal age, (2) saturable, (3) induced postsynaptically, (4) reversible, and (5) not associated

40 Inhibition of Dscam either pre- or postsynaptically abolishes the emergence of synaptic tra

41 Postsynaptically, ACh receptor clusters are markedly inc

42 Postsynaptically, AChR clusters in HSA-beta-cat(flox(ex3

43 toreceptor function, they may participate in postsynaptically activated short-loop feedback modulatio

44 Postsynaptically, altered clustering and increased synap

45 ) R2 immunoreactivity was commonly expressed postsynaptically, although immunoreactive preterminal ax

46 oup I mGluR subtypes was primarily expressed postsynaptically, although light mGluR1a labeling was oc

47 n-dependent manner while having no effect on postsynaptically (AMPA) evoked currents recorded in the

48 of PKA, but the roles of presynaptically and postsynaptically anchored forms of PKA in late-phase LTP

49 omuscular junction, amphiphysin is localized postsynaptically and amphiphysin mutants have no major d

50 ads to both an increased expression of GluA1 postsynaptically and an increase in vesicle pool size an

51 rdingly, dNedd4Lo was colocalized with dAmph postsynaptically and at muscle T-tubules.

52 us and ACx, we show that TC LTP is expressed postsynaptically and depends on group I metabotropic glu

53 strength in pyramidal cells that is induced postsynaptically and depends on metabotropic glutamate r

54 In adult mouse cortex, ABHD6 was located postsynaptically and its selective inhibition allowed th

55 ng-term potentiation (LTP), expressed mostly postsynaptically and occluded by inhibitory avoidance tr

56 tablishing that 5-HT2A receptors are located postsynaptically and presynaptically, (ii) demonstrating

57 utamatergic neurotransmission by acting both postsynaptically and presynaptically.

58 The synaptic potentiation occurs postsynaptically and probably involves up-regulation of

59 IgSF21 localizes postsynaptically and recruits axonal neurexin2alpha in a

60 ulation frequency (0.2 Hz) that is expressed postsynaptically and requires the activation of ionotrop

61 factor attachment protein receptors (SNAREs) postsynaptically and that nicotinic stimulation rapidly

62 ition was GABA-mediated, acted both pre- and postsynaptically and was fast enough to either prevent o

63 n the plasma membranes of LC neurons pre- or postsynaptically and whether there is differential relea

64 E2's acute effect was mediated postsynaptically, and required Ca(2+) influx through the

65 A Y1 receptor activates a K+ current postsynaptically, and several receptor types appear to i

66 naptic transmission both presynaptically and postsynaptically, and this could be independent of ASICs

67 In addition, GluR6-KARs, localizing pre- and postsynaptically, are critically involved in inhibiting

68 ecules (CAMs), expressed presynaptically and postsynaptically, are thought to guide neurons to their

69 Moreover, this lipase accumulates postsynaptically around afferent excitatory synapses in

70 ically as a decrease in transmitter release, postsynaptically as a decrease in the synaptic current e

71 uronal information storage that is expressed postsynaptically as a functional down-regulation of alph

72 membrane ligand for Eph receptors, functions postsynaptically as a receptor to transduce reverse sign

73 r striatal LTD is thus likely to be released postsynaptically as a retrograde messenger.

74 hat MHCI proteins were present both pre- and postsynaptically at all ages examined.

75 hat fusion-competent Syt 4 vesicles localize postsynaptically at both neuromuscular junctions (NMJs)

76 y at axon terminals and initial segments and postsynaptically at dendritic spines and shafts.

77 erotonergic changes both presynaptically and postsynaptically at four different motor states (baselin

78 n kinase II (CaM kinase II) are concentrated postsynaptically at glutamatergic synapses on glutamater

79 ace receptor that has been most well-studied postsynaptically at mammalian neuromuscular junctions.

80 2 subunits are localized presynaptically and postsynaptically at mossy fiber synapses where they most

81 ZO1 is asymmetrically localized exclusively postsynaptically at neuronal contacts where it functions

82 ugh these receptors, 5-HT acts both pre- and postsynaptically at pyramidal (PyN) neurons and parvalbu

83 he intermediate filament nestin is localized postsynaptically at rodent neuromuscular junctions.

84 t alpha7nAChR allows for activation of NMDAR postsynaptically at synapses lacking AMPAR.

85 tingly, we observed that GluR1 was expressed postsynaptically at the climbing fibers (CF) synapse at

86 hat Cortactin is present presynaptically and postsynaptically at the Drosophila NMJ and that it is a

87 ophila Hts/Adducin is enriched both pre- and postsynaptically at the NMJ.

88 ynaptically, at glutamatergic terminals, and postsynaptically, at apical dendrites, without inhibitin

89 It is concluded that cannabinoids may postsynaptically augment the excitability of CA1 pyramid

90 l ligand for neurexins that may be localized postsynaptically based on its well characterized interac

91 These differences might arise postsynaptically because of differential postsynaptic at

92 Nicotinic receptors are expressed postsynaptically before hearing onset and switch to pres

93 alizes both at the presynaptic terminals and postsynaptically, being frequently localized on the syna

94 Here we demonstrate that adaptation begins postsynaptically but is ultimately communicated to presy

95 asymmetric synapses (n = 70) (both pre- and postsynaptically but predominantly in the postsynaptic e

96 synaptic physiology both presynaptically and postsynaptically, but the regulatory mechanisms remain o

97 a-opioid receptor (KOR) is detected pre- and postsynaptically, but the subcellular localization, tran

98 We show that endocannabinoids are released postsynaptically by a synuclein-dependent and SNARE-depe

99 2+) entry through N-type Ca(2+) channels and postsynaptically by acetylcholine acting on nicotinic re

100 This potentiation was expressed postsynaptically by AMPA-type glutamate receptors and re

101 This segregation is further established postsynaptically by histamine-receptor-expressing unicol

102 ine GABAergic system that exerts its effects postsynaptically by inhibiting NPO neurons, resulting in

103 In the model, slow responses, generated postsynaptically by mGluR-mediated phosphoinositide hydr

104 es indicate that these changes are regulated postsynaptically by neuropeptide Y (NPY), an adrenal cot

105 ed by excessive excitation may be determined postsynaptically by the way in which different target ce

106 he RecA(Ec) protein strand exchange reaction postsynaptically, by binding to the displaced single str

107 Postsynaptically, CAM II kinase-alpha immunoreactivity w

108 ow that a nitric oxide (NO) signal generated postsynaptically can regulate endocytosis and at least o

109 Postsynaptically, changes in synaptic strength can occur

110 ce for the preferential transport of AAV1 to postsynaptically connected neurons and reveal its spread

111 ory neurotransmission in the BLA-CeL pathway postsynaptically, consistent with the known roles of PAC

112 Postsynaptically, DCAF12 is expressed in muscle nuclei a

113 synaptic plasticity can be expressed pre- or postsynaptically depending on a range of factors such as

114 sts, and hippocampal slices in which BVR was postsynaptically depleted showed deficits in electrophys

115 s that drive Fas II expression both pre- and postsynaptically; driving Fas II expression on either si

116 t the hypothesis that, despite being induced postsynaptically, DSI is expressed presynaptically as a

117 How LTP, induced postsynaptically, engages these extracellular traffickin

118 Here we report that MINK and TNIK are postsynaptically enriched proteins whose clustering with

119 that one of the PPXXF motifs, present in the postsynaptically-enriched 190 kDa isoform of ankyrin-G (

120 in the tractus solitarius (ts) and currents postsynaptically evoked by alpha-amino-3-hydroxy-4-isoxa

121 This treatment predominantly increased postsynaptically excitatory synaptic transmission.

122 postsynaptic 5-HT1A receptors; and (3) 5-HT postsynaptically excites pallidal neurons through activa

123 This LTP is postsynaptically expressed and requires activation of an

124 onstrated that functional NMDA receptors are postsynaptically expressed at climbing fiber (CF) to Pur

125 The discovery of a postsynaptically expressed form of cerebellar parallel f

126 Here, we show that postsynaptically expressed LTP is induced selectively in

127 to the patch-pipette saline, suggesting that postsynaptically expressed NMDA receptors are required f

128 We conclude that pre- and postsynaptically expressed plasticity are not interchang

129 This LTP is postsynaptically expressed, enhanced by chelating postsy

130 This long-term depression is postsynaptically expressed, tropomyosin kinase B (TrkB)

131 BAPTA applied postsynaptically failed to block the action of nicotine

132 vermectin sensitivity on worms, is necessary postsynaptically for a functional M3 synapse and for the

133 hat Bdl is required both presynaptically and postsynaptically for delivering SV components in R8 axon

134 rve and muscle and is required both pre- and postsynaptically for normal synaptic growth.

135 in, neither Liprin-alpha nor LAR is required postsynaptically for R cells to project to their correct

136 showed that Fas II is required both pre- and postsynaptically for synaptic stabilization.

137 y contrast, we show Neurobeachin is required postsynaptically for the robust localization of ZO1 and

138 genesis in vitro and in vivo and is required postsynaptically for thrombospondin- and astrocyte-induc

139 s on presynaptic terminals and to GluRdeltas postsynaptically, forming trans-synaptic triads that pro

140 spinal cord, endocannabinoids are mobilized postsynaptically from network neurons and act retrograde

141 neuronal activation glutamate is transported postsynaptically from synaptic clefts and increased lact

142 d receptivity and to induce the formation of postsynaptically functioning CNS synapses.

143 Postsynaptically, Hcrt/Orx produced an inward current an

144 uired for neuronal communication is consumed postsynaptically, i.e., at the target neurons.

145 Postsynaptically, i.e., in striatal neurons, D2R signali

146 hether receptors located presynaptically and postsynaptically in a single cell type display different

147 ns, presynaptically in the granule cells and postsynaptically in CA1 pyramidal cells.

148 evidence that alpha2C-ARs (1) are localized postsynaptically in catecholaminergic neurons of the LC

149 Arousal had similar effects postsynaptically in colliculus neurons, independent of a

150 KARs were distributed both postsynaptically in dendrites and somata (51% of GluR5,6

151 oth receptor subtypes is primarily expressed postsynaptically in dendrites and spines, although presy

152 subpopulation of glutamatergic terminals and postsynaptically in dendrites and spines.

153 ns presynaptically while the other functions postsynaptically in forming the channels.

154 LC-3 channels regulate neuronal excitability postsynaptically in immature neurons.

155 ereas L-type channels were found exclusively postsynaptically in neuronal elements.

156 e receptor, mGluR1 and mGluR5, are expressed postsynaptically in neurons of the subthalamic nucleus (

157 essed in the brain and present both pre- and postsynaptically in neurons.

158 the owl and the chicken, Kv3.1 was targeted postsynaptically in NM and NL.

159 ssing cells, suggesting that MC4-Rs function postsynaptically in some instances and may function pres

160 basal expression occurs presynaptically and postsynaptically in spinal dorsal horn.

161 I mGluRs (mGluR1a and mGluR5) are localized postsynaptically in the dendrites of STN neurons.

162 inergic and catecholaminergic terminals, (2) postsynaptically in the dendritic spines of pyramidal an

163 zed pre- and postsynaptically in the OPL and postsynaptically in the IPL.

164 We find that Babo signaling is required postsynaptically in the muscle, in contrast to the well-

165 owed that the receptor is localized pre- and postsynaptically in the OPL and postsynaptically in the

166 al that both mGuR1a and mGluR5 are localized postsynaptically in the SNr.

167 ellar cortex, where PMCA2a also concentrates postsynaptically, in the spines of Purkinje cells.

168 ere, we report that overexpression of Bcl-xL postsynaptically increases frequency and amplitude of sp

169 Bcl-xL, overexpressed either pre or postsynaptically, increases synapse number, the number a

170 sion (LTD) at the corticostriatal synapse is postsynaptically induced but presynaptically expressed,

171 enhancement of presynaptic facilitation and postsynaptically induced long-term potentiation.

172 It is almost axiomatic in neuroscience that postsynaptically induced NMDA-dependent long-term potent

173 gly, both types of afferent can also undergo postsynaptically induced NMDA-receptor-dependent LTP.

174 LTP at MF-SOMI synapses was postsynaptically induced, required increased intracellul

175 cate that 5-HT-containing axon terminals may postsynaptically inhibit GABAergic neurons and their tar

176 ded hypoglossal motoneurons were found to be postsynaptically inhibited on the basis of analyses of t

177 ted and form a complex capable of binding to postsynaptically localized ADGRB3, thereby creating a no

178 tropic glutamate receptor type 6 (mGluR6) is postsynaptically localized and expressed only in the den

179 Recent reports have revealed that postsynaptically localized ASICs contribute to the excit

180 Our results suggest that PGE2 synthesized by postsynaptically localized COX-2 functions as a retrogra

181 Together, these results suggest that postsynaptically localized MHCl acts in homeostatic regu

182 em, we demonstrate that neuroligin-1 and -2, postsynaptically localized proteins, can trigger the de

183 -spiking interneurons (PV-INs) by recruiting postsynaptically-localized a(2)-adrenergic receptors (AR

184 Neurogranin (Ng) is a brain-specific, postsynaptically located protein kinase C (PKC) substrat

185 initiates mechanistically distinct forms of postsynaptically maintained LTD and these LTDs are diffe

186 m2 receptors that are located both pre- and postsynaptically mediate many cholinergic effects in the

187 Postsynaptically MGM/PIN terminals everywhere synapsed o

188 Although SCs express CB1Rs postsynaptically, neither high-frequency firing of SCs n

189 ily of synaptic scaffolding proteins located postsynaptically on excitatory synapses.

190 and 5-HT(2)Rs are thought to be located only postsynaptically on IO cells.

191 central melanocortins act presynaptically or postsynaptically on MC4-Rs is also unknown.

192 eurons and by delta opioid receptors located postsynaptically on pallidostriatal feedback neurons.

193 b and GABA(B)R2 were more strongly expressed postsynaptically on pyramidal and nonpyramidal cells tha

194 unctional GluK1-containing KARs were present postsynaptically on VP neurons but not on OT cells.

195 ed pre-post assembly in conjunction with two postsynaptically operating, antagonistic Neuroligin spec

196 jor proportion of GABA(B)Rs may be expressed postsynaptically or on GABAergic terminals.

197 l synapses in which it was expressed pre- or postsynaptically, or both, in spinal laminae I-IV.

198 his plasticity is expressed presynaptically, postsynaptically, or both.

199 t was expressed either independently pre- or postsynaptically, or in a mixture of both ways.

200 gh synaptic NMDARs are predominately located postsynaptically, recent evidence suggests that they may

201 m) decreases neocortical network activity by postsynaptically reducing excitatory synaptic transmissi

202 ontrol synaptic growth and axon guidance and postsynaptically regulate endocytosis of glutamate recep

203 the CNS and are present presynaptically and postsynaptically regulating synaptic transmission and ex

204 ression of wild-type Gs alpha either pre- or postsynaptically rescued the mutational defects in bouto

205 synapses that are presynaptically active but postsynaptically silent and work in concert with other,

206 functional AMPA receptors and are therefore postsynaptically silent at resting membrane potentials.

207 Our results confirm the existence of postsynaptically silent synapses and demonstrate that th

208 and ion channels) and the transformation of postsynaptically silent synapses into functional ones.

209 SCs, suggesting the selective enhancement of postsynaptically silent synapses upon inactivation of al

210 physiological evidence for the existence of postsynaptically silent synapses.

211 structural synapses, but these synapses are postsynaptically silent.

212 Many excitatory synapses are thought to be postsynaptically 'silent', possessing functional NMDA bu

213 rtate receptor) and CaMKII signalling and on postsynaptically synthesized BDNF.

214 Postsynaptically, T-588 reduced acetylcholine currents a

215 anterograde transsynaptic tools for tagging postsynaptically targeted neurons remain under developme

216 Using postsynaptically tethered calcium sensor GCaMP, we inves

217 l axons formed a normal whisker map, whereas postsynaptically the cytoarchitecture of layer IV neuron

218 ic plasticity can be expressed both pre- and postsynaptically, the functional consequences of this ar

219 Postsynaptically, the muscarinic acetylcholine receptor

220 Postsynaptically, the opioids activate a potassium condu

221 Postsynaptically, the quantal size as well as number and

222 Although the receptors can act both pre- and postsynaptically, their physiological significance is un

223 that HSPGs function both presynaptically and postsynaptically; these defects could be rescued by appr

224 released, mature TC synapses can express LTD postsynaptically through group I metabotropic glutamate

225 t fasting and leptin act presynaptically and postsynaptically to alter GABAergic drive to GnRH neuron

226 e NPY receptors act both presynaptically and postsynaptically to depress GABA-mediated Ca2+ rises.

227 Synaptic input may cause Ca(2+) accumulation postsynaptically to evoke a Ca(2+)-activated inward curr

228 tivated non-specific cation current (I(CAN)) postsynaptically to generate 10-30 mV transient depolari

229 y to inhibit sensory transmitter release and postsynaptically to inhibit motor neuron excitability.

230 The DinD protein, however, acts postsynaptically to inhibit RecA during an on-going DNA

231 ically to promote normal synaptic growth and postsynaptically to maintain normal levels of evoked tra

232 to act through TrkB presynaptically, but not postsynaptically, to modulate LTP.

233 hat Dnlg2 functions both presynaptically and postsynaptically together with Neurexin to determine the

234 lly strong lateral inhibition, both pre- and postsynaptically, triggered by distant motion.

235 Postsynaptically, TrkB controls the localization of a sc

236 In this model, the LGMD multiplies postsynaptically two inputs (one excitatory, one inhibit

237 campal inhibitory synapses that is triggered postsynaptically via glutamate receptor activation but i

238 On one hand, dynorphin acts postsynaptically via KORs on VP GABAergic neurons to pro

239 o trigeminal motoneurons presynaptically and postsynaptically via presynaptic inhibition and by reduc

240 This modulation occurred postsynaptically, was mediated primarily by mGluR5, and

241 iclin II (Fas II) is localized both pre- and postsynaptically where it controls synapse stabilization

242 brane traffic by phosphorylation also occurs postsynaptically, where it contributes to synaptic plast

243 types are found in neurons, both pre- and/or postsynaptically, where they mediate modulatory roles an

244 ppocampal cultures, where it is co-localized postsynaptically with calcium/calmodulin-dependent prote

245 MHCI protein is colocalized postsynaptically with PSD-95 in dendrites of hippocampal

246 males and females and found that LTP occurs postsynaptically with similar magnitudes in both sexes.

247 ents recorded in serotonergic neurons in DRN postsynaptically, without significantly affecting presyn

248 Traditionally, NMDA receptors are located postsynaptically; yet, putatively presynaptic NMDA recep