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1 d in the stroma and targeted to the membrane posttranslationally.
2 suggesting that Puf3p activity is regulated posttranslationally.
3 nition by SRP, SRP was found to bind to YohP posttranslationally.
4 for shelterin subunits when TIN2 is depleted posttranslationally.
5 -666 and Cys-673-Cys-685, that was completed posttranslationally.
6 encoded in the genetic code, but synthesized posttranslationally.
7 or Kruppel-like factor 5 (KLF5) is regulated posttranslationally.
8 nifest in the cytoplasmic compartment co- or posttranslationally.
9 that a number of phage proteins are modified posttranslationally.
10 tment fails to occur if the lipids are added posttranslationally.
11 Z regulates the concentration of FlhD(4)C(2) posttranslationally.
12 ains its phospholipid recruitment capability posttranslationally.
13 nslation, whereas the CHIP E3 appears to act posttranslationally.
14 n accumulation by GrIP overexpression occurs posttranslationally.
15 nscriptional level, but it is also regulated posttranslationally.
16 I1 ubiquitination and stabilized the protein posttranslationally.
17 In addition, Naa10 can act independently to posttranslationally acetylate a distinct set of substrat
20 demonstrate that purified RimL is capable of posttranslationally acetylating L12, exhibiting a V(max)
21 ntiation in vitro and in vivo and signals to posttranslationally activate myogenic basic helix-loop-h
22 gnaling and TNFalpha release, is rapidly and posttranslationally activated by a variety of signaling
23 anase, overexpressed by glomerular cells and posttranslationally activated by cathepsin L of tubular
24 igand shedding is that it can be rapidly and posttranslationally activated in a manner that requires
25 nscriptional activator for the nif genes, is posttranslationally activated only by the uridylylated f
26 [familial intrahepatic cholestasis 1 (FIC1)] posttranslationally activated the farnesoid X receptor (
27 we showed that Pseudomonas aeruginosa T6S is posttranslationally activated upon phosphorylation of Fh
28 otein also accumulated, and was subsequently posttranslationally activated, during the compatible int
29 eria to humans, numerous proteins have to be posttranslationally acylated to become biologically acti
30 peptides, the serine-3 residue of ghrelin is posttranslationally acylated with an n-octanoic acid, a
34 r bridge (sactionine bond) that is installed posttranslationally and is absolutely required for their
36 ins can associate with membranes co- but not posttranslationally, and we perform a structure function
37 revealed that this small GTPase is modified posttranslationally at Ser(76) by a phosphorylcholine mo
40 MP/PKA stimulation regulates CFTR biogenesis posttranslationally, based on predicted 14-3-3 binding m
42 Because channels and gap junctions are gated posttranslationally, bioelectrical networks have their o
43 racting with polypeptide chains both co- and posttranslationally, but it is currently not clear how d
44 nearly all thylakoid transmembrane proteins posttranslationally, but mechanisms in the stroma that a
49 suggest that the C-tail domain is recognized posttranslationally by a specialized translocation appar
50 ges with reversed stereochemistry introduced posttranslationally by a specific radical-SAM sactisynth
51 us of the G(N) precursor protein and removed posttranslationally by endoproteolysis, were required fo
53 mixed-acid fermentation, which is activated posttranslationally by PFL-activating enzyme (PFL-AE).
54 biliary damage, PC2 expression is modulated posttranslationally by the proteasome or the autophagy p
57 transgene for MCD (Tg-fMCD(Skel)) stabilized posttranslationally by the small molecule, Shield-1.
58 induce reactivation were tightly controlled posttranslationally by the synthetic hormone tamoxifen.
59 al marker of mesenchymal GSCs, are regulated posttranslationally by ubiquitin-specific protease 9X-me
62 ry loop involving the ER Insig proteins, and posttranslationally, by Insig-dependent protein degradat
63 the 21.5-kD sieve element-specific ENOD are posttranslationally cleaved from the precursor protein,
66 Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins, Gn a
68 e small ubiquitin-like modifiers (SUMOs) are posttranslationally conjugated to eukaryotic cellular pr
69 meostasis whereby an E3 ubiquitin ligase may posttranslationally control components of the transcript
70 n of PaO activity in canola seed was largely posttranslationally controlled and it was at this level
71 hat the activity of many acid:CoA ligases is posttranslationally controlled by acylation of an active
73 and biochemical analyses, we show that FliZ posttranslationally controls HilD to positively regulate
77 bilized and that their alpha-tubulin subunit posttranslationally detyrosinated after engagement of th
79 , enhanced activity of the RTA promoter, and posttranslationally enhanced RTA's trans-activating capa
80 n also be generated through modifications of posttranslationally exposed pro-N-degrons of otherwise s
81 chaperoning the newly synthesized TA protein posttranslationally from the ribosome to the endoplasmic
82 ther clock genes, implying that for dCLOCK a posttranslationally generated rhythm is more important t
83 Peroxisomes are eukaryotic organelles that posttranslationally import proteins via one of two conse
85 lear genome, synthesized in the cytosol, and posttranslationally imported into the organelle in an en
86 C-signaling activates FruA at least ninefold posttranslationally in order to commit a cell to spore f
88 we show here that indeed WT SOD1 is modified posttranslationally in sporadic ALS and is iper-oxidized
89 Escherichia coli, chemoselectively modified posttranslationally in the cell-free homogenate, and dir
90 tivation and PER-TIM repression is regulated posttranslationally, in part through rhythmic phosphoryl
92 s suggest that PagL enzymatic deacylation is posttranslationally inhibited by membrane environments,
94 ehydroalanine and dehydrobutyrine, which are posttranslationally installed by class I lanthipeptide d
97 peptides in which the third last residue is posttranslationally isomerized to the d configuration.
98 HiToP ribosomal protein genes are regulated posttranslationally, likely at the level of protein stab
99 displayed delayed growth, reduced levels of posttranslationally lipoylated mitochondrial proteins, h
100 able a wide diversity of natural, unnatural, posttranslationally modified (methylated, glycosylated,
104 have developed a strategy in which otherwise posttranslationally modified amino acids are genetically
105 of MCR (McrA) typically contains four to six posttranslationally modified amino acids near the active
106 onserved cysteines within the MYXO-CTERM are posttranslationally modified and are required for TraA c
108 a mechanism by which CDC-family proteins are posttranslationally modified and regulated and help expl
110 tly enhanced the kinase activity of Src, and posttranslationally modified at least one additional mem
112 dyscrasias and that dominant inheritance of posttranslationally modified autoantigenic paratargs is
115 omegalovirus has been previously shown to be posttranslationally modified by covalent conjugation to
116 hemagglutinin (HA) contains three cysteines, posttranslationally modified by covalently bound fatty a
118 the major autoantigen in Graves' disease, is posttranslationally modified by intramolecular cleavage
119 rvariable C-terminal domain (HVD) of Rabs is posttranslationally modified by isoprenyl moieties that
120 at Lys-392 of the antibiotic-binding site is posttranslationally modified by N(zeta)-carboxylation.
121 licated in regulating the levels of proteins posttranslationally modified by nitric oxide on cysteine
123 The differentially expressed proteins are posttranslationally modified by phosphorylation and glyc
124 ed that endogenous human and Xenopus BAF are posttranslationally modified by phosphorylation and pote
125 cancer-associated RNA-binding protein La is posttranslationally modified by phosphorylation and sumo
126 a multifunctional regulatory protein that is posttranslationally modified by phosphorylation during v
129 ellular pathogen Listeria monocytogenes, was posttranslationally modified by S-glutathionylation at t
132 isordered regions, and are recognized and/or posttranslationally modified by structured domains of th
139 x virus type 1 (HSV-1) envelope proteins are posttranslationally modified by the addition of sialic a
140 usly, we have demonstrated that ErbB4 ICD is posttranslationally modified by the small ubiquitin-like
141 d that the E. chaffeensis effector TRP120 is posttranslationally modified by ubiquitin (Ub) and that
143 lysine residues at the p53 C terminus can be posttranslationally modified by various mechanisms, incl
144 I molecules can present to the immune system posttranslationally modified cytosolic peptides carrying
147 eal host from which to obtain high levels of posttranslationally modified eukaryotic proteins for x-r
149 iquitin-conjugated tau, suggesting that this posttranslationally modified form of tau may be rapidly
150 phorylate Baf53 in vitro, implying that this posttranslationally modified form relieves the suppressi
153 or 2 in eukaryotes (eEF-2) contains a unique posttranslationally modified histidine residue, termed d
154 tem, as well as by the semisynthesis of dual posttranslationally modified histone proteins in live ce
157 nstrate that p53 associated with SV40 LT was posttranslationally modified in a manner consistent with
158 eptor alpha (IFN-gammaR alpha) is stable but posttranslationally modified in herpes simplex virus 1(F
159 at U(S)3 interacts with PDCD4, that PDCD4 is posttranslationally modified in infected cells both in a
162 atic asialoglycoprotein receptor (ASGP-R) is posttranslationally modified in the Golgi en route to th
163 the T cell-attracting chemokine CCL2 can be posttranslationally modified in the tumor microenvironme
167 the absence of a structure for full-length, posttranslationally modified membrane receptors, our app
168 ulfur amino acid-containing diet resulted in posttranslationally modified microbial tryptophanase act
169 sin-1 is due to its unique ability to select posttranslationally modified microtubules for cargo tran
170 ibrin may function, in part, to downregulate posttranslationally modified MRN complex components afte
172 O by secreting a small ribosomally produced, posttranslationally modified natural product called meth
173 tides are a class of ribosomally synthesized posttranslationally modified natural products found in b
175 ctions as an epigenetic reader that binds to posttranslationally modified or unmodified histone H3 ta
178 ns belong to the ribosomally synthesized and posttranslationally modified peptide (RiPP) family of na
179 es that generate ribosomally synthesized and posttranslationally modified peptide (RiPP) natural prod
181 (RumC), a novel ribosomally synthesized and posttranslationally modified peptide (RiPP) produced by
182 ccin C (RumC), a ribosomally synthesized and posttranslationally modified peptide (RiPP) with potent
183 roduce lantibiotics, genetically encoded and posttranslationally modified peptide antibiotics, which
185 es are mostly nonmodified peptides, although posttranslationally modified peptide epitopes have been
186 Planosporicin is a ribosomally synthesized, posttranslationally modified peptide lantibiotic produce
187 s are a class of ribosomally synthesized and posttranslationally modified peptide natural products (R
190 itides are plant ribosomally synthesized and posttranslationally modified peptides (RiPPs) of various
192 re a subclass of ribosomally synthesized and posttranslationally modified peptides (RiPPs) with compl
195 are a family of ribosomally synthesized and posttranslationally modified peptides containing (methyl
197 antipeptides are ribosomally synthesized and posttranslationally modified peptides containing thioeth
198 veral classes of ribosomally synthesized and posttranslationally modified peptides involves dehydrati
202 on would be beneficial for studies of highly posttranslationally modified protein such as histones.
205 ivo concentrations of metabolites, total and posttranslationally modified proteins, and develop a con
207 Mass spectrometry enables global analysis of posttranslationally modified proteoforms from biological
208 novel, recurrent hotspot was identified at a posttranslationally modified residue in the histone H2B
209 me, suggesting that interactions between the posttranslationally modified residues do not exert a maj
210 rientation of the missense mutations and the posttranslationally modified residues, it is probable th
214 35Y, and R46L, respectively), as well as two posttranslationally modified sites, sulfated Y38 and pho
217 postsynaptic terminals, and this abnormally posttranslationally modified tau is enriched in synapton
218 dule in which the sensor receptor protein is posttranslationally modified to attenuate ligand-induced
219 odel for any DNA-binding protein that can be posttranslationally modified to change its affinity for
221 protein contained a signal sequence and was posttranslationally modified to produce three hydroxypro
222 lantibiotics use two peptides that are each posttranslationally modified to yield two functionally d
224 1.7 driven by hierarchical interactions with posttranslationally modified versions of the binding par
226 at b-type flagellin from strain PAO1 is also posttranslationally modified with an excess mass of up t
228 tes of the prion protein or PrP(C) PrP(C) is posttranslationally modified with N-linked glycans and a
229 a cyclic 26-amino acid (aa) peptide that is posttranslationally modified with one disulfide and one
231 wo experimental models of COPD and increased posttranslationally modified WNT-5A in human COPD tissue
232 have previously reported that L1 and L2 are posttranslationally modified, but it is uncertain whethe
233 d germline-limited genes expressed, and some posttranslationally modified, during genome rearrangemen
235 on initiation have been found to be mutated, posttranslationally modified, or differentially expresse
236 ategy to identify amino acids in E2 that are posttranslationally modified, we reported that tyrosine
240 lin, making this antibiotic the most heavily posttranslationally-modified peptide known to date.
241 monstrated that the PARP-1 protein binds and posttranslationally modifies HuR in PARPi-treated PDAC c
242 GLN1) is a key oxygen sensor in mammals that posttranslationally modifies hypoxia-inducible factor al
243 sociated with receptor tyrosine kinases, and posttranslationally modifies members of the Src family o
244 ons describe a pharmacological strategy that posttranslationally modifies nephrin and the effects of
245 e (OGT) is an essential cellular enzyme that posttranslationally modifies nuclear and cytoplasmic pro
246 ctrophilic species in equilibrium with urea, posttranslationally modifies proteins through a process
247 ases, suggesting that human homologs of NisC posttranslationally modify a cysteine of a protein subst
248 ymerase (PARP) is a family of enzymes, which posttranslationally modify a range of proteins and regul
249 e polymers of ADP-ribose (pADPr or PAR) that posttranslationally modify its target proteins, such as
250 de the ability of cells to properly fold and posttranslationally modify secretory and transmembrane p
251 plexes are key gene regulatory factors which posttranslationally modify the histone component of chro
252 lymerase (PARP) superfamily of proteins that posttranslationally modify themselves and target protein
253 elial cell surface plasminogen activation by posttranslationally modifying annexin A2, the coreceptor
254 lpha (ERalpha) can modulate gene activity by posttranslationally modifying histone tails at target pr
257 ein Isu, the abundance of which is regulated posttranslationally on disruption of the cluster biogene
259 oxidation, in which methionine residues are posttranslationally oxidized to methionine sulfoxide.
260 l ubiquitin-like modifier (SUMO) to proteins posttranslationally, plays an important role in regulati
261 tion factor beta-catenin, which is otherwise posttranslationally processed by a destruction complex a
263 ain their ability to produce full-length and posttranslationally processed envelope proteins in cell
264 tructural glycoproteins, Gn and Gc, that are posttranslationally processed from precursors PreGn and
266 enome RNA into polyproteins that are co- and posttranslationally processed into intermediate and matu
267 , and the majority of this protein is likely posttranslationally processed into the 65-kD protein PSR
268 V) genome encodes a capsid precursor that is posttranslationally processed to release the mature caps
271 GT1 acts as an ER quality control sensor by posttranslationally reglucosylating glycans on slow-fold
272 e a similar C-terminal degradation system to posttranslationally regulate the activity of DesA3 and o
275 e yeast Smf1p Nramp manganese transporter is posttranslationally regulated by environmental manganese
277 re are dozens of cysteine proteases that are posttranslationally regulated by processing, environment
278 yzes the reduction of oxygen to water and is posttranslationally regulated by redox mechanisms and 2-
279 20 histone methyltransferase PR-Set7/Set8 is posttranslationally regulated by the PCNA-dependent CRL4
282 on-mediated p27(Kip1) and p21 increases were posttranslationally regulated via the down-regulation of
284 n convertase subtilisin/kexin type 9 (PCSK9) posttranslationally regulates hepatic low-density lipopr
285 tion regulates the proteolysis of PALs, thus posttranslationally regulating phenylpropanoid metabolis
288 ured under normoxic conditions, HIF1alpha is posttranslationally stabilized in a manner dependent upo
289 in inhibitory activity that we predict to be posttranslationally sulfated at two conserved tyrosine r
290 01 from the Amblyomma cajennense tick can be posttranslationally sulfated at two tyrosine residues, a
294 ed proteins must be recognized and delivered posttranslationally to the endoplasmic reticulum or mito
295 erved in tRNA that are believed to be formed posttranslationally via a biosynthetic intermediate that
296 o, small secretory proteins can enter the ER posttranslationally via a transient cytosolic intermedia
297 The Sec62-dependent translocation occurs posttranslationally via the Sec61 translocon and require
298 ition of epigenetic dioxygenases, as well as posttranslationally, via covalent modification of cystei
299 L2 are tail-anchored proteins that associate posttranslationally with membranes and likely require sp