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1          The polydactyly of GCPS is commonly preaxial and that of PHS is typically central or postaxi
2 ent, normal limb buds downregulate Fgf4, the preaxial cells do not regulate, and a truncated anteropo
3 ng all Shh-expressing cells) is removed, the preaxial cells reform a normal-shaped talpid(2) limb bud
4  selectively antagonizes formation of 'true' preaxial condensations that branch from this main axis (
5 tionarily independent in the autopodium, and preaxial dominance facilitates stabilization of the numb
6               The mechanistic basis for this preaxial dominance has remained an enigma and has even b
7  We demonstrate this shift from postaxial to preaxial dominance in mouse results from excess Gli3 rep
8                                              Preaxial dominance is a notable feature of limb regenera
9              This distribution suggests that preaxial dominance is a primitive developmental pattern
10                                We found that preaxial dominance is seen in the distal carpals/tarsals
11 regenerate the limb, and the contribution of preaxial dominance to limb regeneration is unclear.
12 st digits to form are the two most anterior (preaxial dominance).
13 rts (digits III to V), a phenomenon known as preaxial dominance, whereas in amniotes and anurans, the
14 togenesis in salamanders is characterized by preaxial elements, digits I and II forming earlier than
15     In Eusthenopteron, dorsal rays cover the preaxial endoskeleton slightly more than ventral rays.
16 regeneration and may also be involved in the preaxial patterning during limb development.
17 lamanders), whose limb elements develop with preaxial polarity and who are also notable for their uni
18                            Here we show that preaxial polarity in limb development was present in var
19  retained regenerative capacities as well as preaxial polarity in limb development.
20 ouse is atavistic and uncovers an underlying preaxial polarity in mammalian limb formation.
21 salamanders are unique in showing a reversed preaxial polarity in patterning of the skeletal elements
22 owever, recent fossil evidence suggests that preaxial polarity represents an ancestral rather than de
23                                              Preaxial polydactyly (PPD) is a common limb-associated b
24 hh expression in the anterior limb bud and a preaxial polydactyly (PPD) skeletal phenotype.
25 efine a pathogenetic mechanism that leads to preaxial polydactyly (PPD).
26 nd Rim4; [1] [2] [3] [4] [5]) have in common preaxial polydactyly and longbone abnormalities.
27 expression of sonic hedgehog, with resulting preaxial polydactyly and mirror image duplications of po
28 urring mouse mutations with the phenotype of preaxial polydactyly exhibit ectopic Shh expression at t
29  activation of Sox9 in the digit 1 field and preaxial polydactyly in a Gli1- and Gli3-dependent manne
30   The mouse doublefoot (Dbf) mutant exhibits preaxial polydactyly in association with craniofacial de
31 This result suggests that Lmbr1 may underlie preaxial polydactyly in both mice and humans.
32                 The major locus for dominant preaxial polydactyly in humans has been mapped to 7q36.
33                         The mutant displayed preaxial polydactyly in the hindlimbs of heterozygous em
34 r-ectopic expression of SHH and induction of preaxial polydactyly is induced secondary to increased S
35 Our data indicates that in Dorking chickens, preaxial polydactyly is initiated independent of Shh.
36 is of the corpus callosum, tibial hemimelia, preaxial polydactyly of the feet, and intellectual disab
37 r the polydactyly ems (Pde) mutation display preaxial polydactyly of the hindlimbs, and homozygous sy
38 niofacial malformations, microphthalmia, and preaxial polydactyly of the right hindlimb.
39 reduced, limb skeletal defects progress from preaxial polydactyly to girdle reduction combined with h
40 nd resulting limb abnormalities that include preaxial polydactyly with duplication of posterior skele
41 efective digit patterning including hindlimb preaxial polydactyly with posterior digit transformation
42                             In the hindlimb, preaxial polydactyly with variable expressivity was seen
43  we show that the chromosome 7q36 associated preaxial polydactyly, a frequently observed congenital l
44 contrast, loss of anterior T-box3 results in preaxial polydactyly, as seen with dysfunction of primar
45 nal cord, as well as neural tube defects and preaxial polydactyly, consistent with increased Shh sign
46                   The congenital abnormality preaxial polydactyly, extra digits, is an example of thi
47                        Another malformation, preaxial polydactyly, was exclusively seen in heterozygo
48  hemimelia, developmental hip dysplasia, and preaxial polydactyly, were also present in some family m
49  as acd/acd, p53(-/-) double mutants exhibit preaxial polydactyly.
50 e anterior margin in many mutants exhibiting preaxial polydactyly.
51  gene have multiple abnormalities, including preaxial polydactyly.
52  least two key respects: their limbs exhibit preaxial skeletal differentiation and do not develop an
53             The hindlimbs of Dorkings form a preaxial supernumerary digit.
54                                 We show that preaxial talpid(2) limb bud mesoderm has polarizing acti
55 , appear to be fundamental to the shift from preaxial to postaxial polarity in formation of the tetra