ライフサイエンスコーパス: prebiotic

1 type of FBD and dose, type, and duration of prebiotic.

2 nger lasting than with other lower molecular prebiotics.

3 a good tool for the production of selective prebiotics.

4 ormula and other food ingredients containing prebiotics.

5 ow we can manipulate them through the use of prebiotics.

6 potential functional ingredient due to their prebiotic action and potential food immuno-modulators.

7 Our results indicate that unified prebiotic activation chemistry could have enabled the jo

8 itionally, the novel compound presented high prebiotic activities as ascertained in the presence of l

9 The level of the prebiotic activity is related to the availability of bet

10 novel "functional ingredient" with potential prebiotic activity mainly towards L. acidophilus.

11 as to isolate, characterize and evaluate the prebiotic activity of inulin and FOS from S. rebaudiana

12 xidant activity, antihypertensive effect and prebiotic activity of Maillard reaction products (MRPs)

13 The prebiotic activity of MOS was evaluated in vitro using t

14 ary fibre on human body are related to their prebiotic activity over the gastrointestinal tract (GIT)

15 ons as potential functional ingredients with prebiotic activity toward well-known probiotic bacteria,

16 Potential prebiotic activity was observed in all extracts, some in

17 n MRP (p < 0.05), which indicated a possible prebiotic activity.

18 quality of gluten free (GF) bread and have a prebiotic activity.

19 des (XOS and AXOS) are of interest for their prebiotic activity.

20 rding short-chain fatty acid concentrations, prebiotic administration increased cecal acetate and pro

21 rate that diamidophosphate (DAP)-a plausible prebiotic agent produced from trimetaphosphate-efficient

22 of a synbiotic combination of probiotic and prebiotic agents affected liver fat content, biomarkers

23 nflammatory effect with synbiotics than with prebiotics alone.

24 alpha-Aminonitriles-prebiotic alpha-amino acid precursors-are generally prod

25 on of a synbiotic combination (probiotic and prebiotic) altered the fecal microbiome but did not redu

26 logs, which have been discussed as potential prebiotic alternatives to Lys, are ornithine, 2,4-diamin

27 essential molecule as a nitrogen source for prebiotic amino acid syntheses such as the Strecker reac

28 We find that a set of unmodified, prebiotic amino acids binds to prebiotic fatty acid memb

29 m chemistry of all proteinogenic and various prebiotic amino acids.

30 Our model unites prebiotic aminonitrile synthesis and biological alpha-pe

31 The numbers responding were 52/97 (54%) for prebiotic and 59/94 (63%) for placebo, with no differenc

32 s present in acai (Euterpe oleracea) provide prebiotic and anti-genotoxic benefits in the colon.

33 , we address these issues by considering the prebiotic and biological properties of phytochemicals.

34 ation of the processes that supplied H(2) to prebiotic and early microbial systems, as well as those

35 models have shown some promising results for prebiotic and probiotic strategies as prophylaxis or tre

36 Lactulose is a well-known prebiotic and supports the alleviation of digestive diso

37 Eight studies compared prebiotic and synbiotic supplementation, 2 of which repo

38 rt the systemic anti-inflammatory effects of prebiotic and synbiotic supplementation.

39 igosaccharides (POS) have been considered as prebiotics and for the protection of humans from Stx.

40 feed industries, including the production of prebiotics and functional foods.

41 ice bran supplementation provides nutrients, prebiotics and phytochemicals that enhance gut immunity,

42 oating and flatulence, and QoL score between prebiotics and placebo.

43 des are bioactive molecules that function as prebiotics and prevent infections that commonly afflict

44 While nutritional interventions with prebiotics and probiotics seem to exert immunological ef

45 Synbiotics, a mixture of prebiotics and probiotics, have been used for the preven

46 measures in addition to human milk, such as prebiotics and probiotics, to the management of high-ris

47 be achieved by nutritional supplements with prebiotics and probiotics.

48 outcomes in studies examining the effect of prebiotics and synbiotics on systemic inflammation.

49 ted carbohydrates, such as dietary fibre and prebiotics, and can mediate the interaction between the

50 ted carbohydrates, such as dietary fibre and prebiotics, and can mediate the interaction between the

51 This review examines the effect of SCFAs, prebiotics, and pre- and probiotic combinations (synbiot

52 Probiotics, prebiotics, and synbiotics (preparations that combine pr

53 Recently, the effectiveness of probiotics, prebiotics, and synbiotics in reducing postoperative com

54 nd nutraceuticals, which include probiotics, prebiotics, and synbiotics.

55 ASE, International Journal of Probiotics and Prebiotics, and The Cochrane Library databases for rando

56 odulating interventions, such as probiotics, prebiotics, antibiotics, fecal microbiota transplantatio

57 reat number of infant formulas enriched with prebiotics are disposal in the market, however there are

58 Prebiotics are rising in interest in commercial scale pr

59 Prebiotics are selectively fermented by the gastrointest

60 cs (preparations that combine probiotics and prebiotics) are nutritional adjuncts that are emerging a

61 The in vitro prebiotic assay of these molecules indicates a strain sp

62 However, flatulence severity was improved by prebiotics at doses <=6 g/d (SMD: -0.35; 95% CI: -0.71,

63 Questions arise relating to the prebiotic availability of DAP and other amidophosphospho

64 ments that make them potential hot spots for prebiotic biochemistry.

65 ecies lead to the production of ground-state prebiotic building blocks, principally HCN.

66 roduction of functional carbohydrates having prebiotic capacities.

67 results in the highest mineral, protein, and prebiotic carbohydrate concentrations in subsequent kale

68 nutrient composition (protein, mineral, and prebiotic carbohydrate concentrations) and to assess org

69 all intestine, whereas lactulose, recognised prebiotic carbohydrate, reaches the colon to be fermente

70 nd 0-35 ug Se) as well as 5.7-8.7 g of total prebiotic carbohydrates, including sugar alcohols (0.4-6

71 f daily essential mineral micronutrients and prebiotic carbohydrates.

72 s algorithm that generates a full network of prebiotic chemical reactions accessible from these subst

73 d thus redox-active, perhaps able to promote prebiotic chemical reactions.

74 t only viable as functional compartments for prebiotic chemistries, they can outperform higher molecu

75 Prebiotic chemistry aims to explain how the biochemistry

76 nabolic reaction may indicate a link between prebiotic chemistry and the nature of the first metaboli

77 Carbonaceous meteorites contain clues to prebiotic chemistry because they preserve a record of so

78 Prebiotic chemistry driven by redox-active iron hydroxid

79 Recent results in prebiotic chemistry implicate hydrogen cyanide (HCN) as

80 couple Earth's early evolution with complex prebiotic chemistry in these environments.

81 The challenge of prebiotic chemistry is to trace the syntheses of life's

82 s a potential transitional stage between the prebiotic chemistry of nucleotide synthesis and the cano

83 HMT, which can yield important molecules for prebiotic chemistry such as formaldehyde and ammonia upo

84 role in metabolism and may have impacted the prebiotic chemistry that led to life.

85 itical step toward demonstrating a path from prebiotic chemistry to cellular biology.

86 ind a plausible sequence of transitions from prebiotic chemistry to nascent biology.

87 ic RNA primer extension could illuminate how prebiotic chemistry transitioned to biology.

88 ino acids or peptides could have appeared in prebiotic chemistry under extreme conditions in deep-sea

89 hey also may have important implications for prebiotic chemistry.

90 onment, suggesting favorable environments to prebiotic chemistry.

91 move toward systems-level investigations of prebiotic chemistry.

92 exploring potential nonterrestrial forms of prebiotic chemistry.

93 n proposed to be a product of evolution, not prebiotic chemistry.

94 g several pathways might have their roots in prebiotic chemistry.

95 Prebiotic chemists often study how modern biopolymers, e

96 conditions that make it possible, challenge prebiotic chemists.

97 relin (P = 0.03) increased at 16 wk with the prebiotic compared with placebo.

98 this study was to investigate the effect of prebiotics compared with placebo on global response, gas

99 sis, and offering a mechanism for functional prebiotic compartmentalization in the origins of life.

100 a beneficial effect by increasing desirable prebiotic compounds and decreasing non-nutritional facto

101 ndent core metabolism producible from simple prebiotic compounds.

102 These results suggest that the prebiotic concentrations of urea in a geologically plaus

103 eans of driving condensation reactions under prebiotic conditions to generate mixtures of prospective

104 ides, which would have been inevitable under prebiotic conditions, might decrease the RNA length requ

105 y 2'-deoxyadenosine and 2-deoxyribose, under prebiotic conditions.

106 cant organic phosphorylation under plausible prebiotic conditions.

107 o the possible formation of protocells under prebiotic conditions.

108 N-heterocycles are modified under plausible prebiotic conditions.

109 nzymatic polymerization of RNA strands under prebiotic conditions.

110 s is unclear.We set out to determine whether prebiotic consumption affects iron absorption from a mic

111 ta (GM) composition through the treatment of prebiotics could be a novel preventive measure against c

112 (HPP) and ultrasound (US) on the quality of prebiotic cranberry juice fortified with fructo-oligosac

113 essing has been proven satisfactory to treat prebiotic cranberry juice.

114 stine simulations and may therefore meet the prebiotic criterion of human indigestibility.

115 Recent work has illuminated a potentially prebiotic cyanosulfidic chemistry that activates nucleot

116 obiota to gnotobiotic mice recapitulated the prebiotic-deprived hypertensive phenotype, including car

117 Feeding a prebiotic diet reestablished gene expression of intestin

118 Here we show that lack of prebiotic dietary fiber leads to the development of a hy

119 Prebiotics do not improve gastrointestinal symptoms or Q

120 , either produced as mixtures from plausibly prebiotic dry-down reactions or synthetically prepared i

121 If amphiphilic compounds present on the prebiotic Earth assembled into membranous compartments t

122 On the prebiotic Earth, carbonate-rich lakes were likely abunda

123 lts suggest that viscous environments on the prebiotic Earth, generated periodically by water evapora

124 ed glycosides would have been present on the prebiotic Earth, if any such molecules were present.

125 of inorganic NPs including those existing on prebiotic Earth.

126 lfur clusters could have been synthesized on prebiotic Earth.

127 the problem of organic phosphorylation on a prebiotic Earth.

128 s is the first study reporting the potential prebiotic effect of jucara pulp; however, human studies

129 Inulin-rich foods exert a prebiotic effect, as this polysaccharide is able to enha

130 or cell mass production, while DWB exerted a prebiotic effect, protecting and enhancing the viability

131 eficial to human health in various ways like prebiotic effect, protection from pathogens, anti-inflam

132 es and during storage, low-calorie value and prebiotic effects.

133 recent interest due to their antioxidant and prebiotic effects.

134 t effect greater than expected, also showing prebiotic effects.

135 ng been considered a major limitation to the prebiotic emergence of RNA.

136 saccharides from marine algae can be used as prebiotics, emphasizing their use in human health, their

137 Instead, HMOs act as a bioactive and prebiotic enriching HMO-utilizing bacteria and cause sys

138 The reactivity of these components in a prebiotic environment that supplied sources of chemical

139 se they are more likely to have emerged in a prebiotic environment.

140 During the prebiotic era, radiolytic transformations in the oceans

141 first replicable information carrier of the prebiotic era-that is, prior to the dawn of life(2,3)-ot

142 d depend on selective pressures, even during prebiotic evolution.

143 To incorporate phosphate into biomolecules, prebiotic experiments commonly use molar phosphate conce

144 f unmodified, prebiotic amino acids binds to prebiotic fatty acid membranes and that a subset stabili

145 The impact of lack of prebiotic fiber and the associated mechanisms that lead

146 iotic fiber in the large intestine), or high prebiotic fiber diets.

147 ids ([SCFA)] produced during fermentation of prebiotic fiber in the large intestine), or high prebiot

148 Lack of prebiotic fiber predisposed mice to hypertension in the

149 Mice were fed diets lacking prebiotic fiber with or without addition of gut metaboli

150 cecum weight (an indicator of a diet rich in prebiotic fiber), a 51.8% increase in colon propionate p

151 roducts can be redesigned towards functional prebiotic foods of interest as a cost-effective dietary

152 ts the use of nopal as a functional food and prebiotic for its ability to modify gut microbiota and t

153 or component) has potential application as a prebiotic for regulating gut microbiota composition in d

154 man milk oligosaccharides (HMOs) function as prebiotics for beneficial bacteria in the developing gut

155 y suggesting that murta berries could act as prebiotics for L. casei.

156 tides, followed by an extensive focus on the prebiotic formation of the components of nucleotides-eit

157 Chronic prebiotic FOS+GOS treatment exhibited both antidepressan

158 Prebiotic fructooligosaccharides (FOS) are currently obt

159 ant formula to mimic the molecular sizes and prebiotic functions of human milk oligosaccharides.

160 of studies of probiotics used together with prebiotics have been overall negative.

161 Prebiotics have been shown to improve satiety in adults

162 Here we show that two plausible prebiotic heterocycles, melamine and barbituric acid, fo

163 Such processes may have been of prebiotic importance.

164 yeast cell wall mannan and is widely used as prebiotic in feed supplements for poultry and aquacultur

165 As FOS are mainly used as prebiotic in nutraceutical foods, the reduction or total

166 urpose, we studied the preventive effects of prebiotics in Balb/c mothers during pregnancy and breast

167 Prebiotics increased absolute abundance of bifidobacteri

168 Whether consumption of prebiotics increases iron absorption in infants is uncle

169 eta-d-glucan had good potential for use as a prebiotic ingredient in food, as well as medicinal and p

170 the preservation of foods, as natural dyes, prebiotic ingredients, hydrogels and nanocomplexes.

171 mpleted by caregivers.Compared with placebo, prebiotic intake resulted in significantly higher feelin

172 steviol glycoside, Luo Han Kuo), and natural prebiotic (inulin).

173 raction, modification or production of those prebiotics is highlighted.

174 acidophilus counts, and functionality of the prebiotics L. acidophilus), physicochemical (pH, proteol

175 feed medium for the enzymatic generation of prebiotic lactulose.

176 Homochirality is explained by origin of prebiotic life in one hemisphere of earth and its evolut

177 ded by the direction of magnetic field where prebiotic life originated on Archaean earth.

178 for understanding subcellular organization, prebiotic life, and the origins of disease.

179 and nitrate (beet juice), which may induce a prebiotic-like effect.

180 However, a prebiotic mechanism has yet to be reported for the repli

181 ervates, have been hypothesized as plausible prebiotic micro-compartments due to their ability to seq

182 The combination of probiotics and prebiotics might be useful to treat oral halitosis.

183 in the first year of life with immunoactive prebiotics might have a preventive role against early de

184 mediating surface-catalyzed synthesis in the prebiotic milieu.

185 Prebiotics modified specific gene expression in the hipp

186 The mechanisms for how prebiotics modulate stress physiology remain unclear; ho

187 rolyzed protein infant formula with specific prebiotics modulated the gut microbiota closer to that o

188 ence of the amino acid glycine, an important prebiotic molecule, was deduced based on in situ mass-sp

189 represents the objects that may have brought prebiotic molecules and volatiles such as water to Earth

190 barrierless reactions are capable of forming prebiotic molecules such as nitrogen substituted PAHs (N

191 ependent thermodynamic landscape of putative prebiotic molecules will provide a crucial reference for

192 Meinert et al reported the formation of prebiotic molecules, including ribose, in an interstella

193 hanism for the extraterrestrial synthesis of prebiotic molecules.

194 phosphates were likely an important class of prebiotic molecules.

195 h, drive a complex, continuous enrichment of prebiotic molecules.

196 y leads to the synthesis of extraterrestrial prebiotic molecules.

197 l processes, may act as sources for relevant prebiotic molecules.

198 tween nitrogen bearing acyclic molecules and prebiotic nucleobases along with vitamins found in meteo

199 -dihydroxypropyl)adenine (DHPA), a plausibly prebiotic nucleoside analog of adenosine.

200 Further, by choosing plausibly prebiotic nucleosides, insights may be provided into how

201 obust synthesis of phosphoenol pyruvate from prebiotic nucleotide precursors, glycolaldehyde and glyc

202 ns as to whether the problem of chemistry of prebiotic nucleotide synthesis has been solved.

203 Understanding prebiotic nucleotide synthesis is a long standing challe

204 Xylooligosaccharides (XOS) are prebiotic nutraceuticals that can be sourced from lignoc

205 ebo-controlled, randomized trial, we found a prebiotic (OI) to selectively alter the intestinal micro

206 infant formulas (IFs) are supplemented with prebiotic oligosaccharides, such as galactooligosacchari

207 zed controlled trial to study the effects of prebiotics on body composition, markers of inflammation,

208 the intervention arm, 1354 patients received prebiotic or symbiotic preparations, whereas 1369 patien

209 to manipulate the intestinal microbiota with prebiotics or other agents to prevent or treat obesity.

210 ood potential source of AX for production of prebiotics or other novel products.

211 sponses and dietary exposures, provisions of prebiotics or probiotics have yet to show therapeutic be

212 h additional active ingredients (probiotics, prebiotics, or both) (LPFA) and breastfed infants.

213 gible if they examined the effects of SCFAs, prebiotics, or synbiotics; were delivered orally, intrav

214 mediated the formation and concentration of prebiotic organic monomers, catalyzed their polymerizati

215 N), thus providing a critical entry point to prebiotic organic synthesis.

216 -appreciated obstacle for proposed models of prebiotic organophosphate formation.

217 hesis of RNA and DNA in the context of their prebiotic origins on early earth is a continuing challen

218 n early Earth is critical to elucidating the prebiotic pathways that led to the emergence of primitiv

219 that layered hydroxides could have played in prebiotic peptide formation.

220 s cysteine as both catalyst and precursor in prebiotic peptide synthesis.

221 nvironments are a possible scenario in which prebiotic phosphorylation could have occurred despite un

222 Prebiotic phosphorylation of (pre)biological substrates

223 An alternative prebiotic phosphorylation of 2-thiouridine leads to the

224 This plausible prebiotic phosphorylation process under similar reaction

225 of sauconite, a model for clay minerals, to prebiotic photochemistry.

226 oduction of high value products, such as the prebiotic polyhydroxybutyrate.

227 Prebiotics positively augment gut microbiota and may off

228 d oligosaccharides from H. suaveolens have a prebiotic potential characterized by a delayed but long

229 Recent works provide evidence of the prebiotic potential of arabinoxylan-derived oligosacchar

230 The prebiotic potential of this mixture was demonstrated upo

231 res and arabinose-rich POS2 had the greatest prebiotic potential.

232 xo-purine nucleotides starting from a common prebiotic precursor that yields the beta-ribo-stereochem

233 n, we demonstrate that cyanide (an essential prebiotic precursor) and urea-based solvents could promo

234 ure, in view of a foreseeable use as a novel prebiotic preparation.

235 naturally present in human milk that act as prebiotics, prevent pathogen binding, modulate the immun

236 Such a model could aid in the development of prebiotic, probiotic, or synthetic therapeutics that dec

237 at directly target the microbiota, including prebiotics, probiotics, synbiotics and faecal microbiota

238 he formation of organophosphate molecules by prebiotic processes relies on nonenzymatic synthesis.

239 It is thought that prebiotic processes were able to synthesize short random

240 Dietary prebiotics produce favorable changes in the commensal gu

241 b molasses was converted into a high-quality prebiotic product with decreased sucrose content and red

242 lactating mice with nondigestible GOS/inulin prebiotics promotes a long-term protective effect agains

243 PS from Laffan and Wonderful mesocarp showed prebiotic properties in vitro with Lactobacillus and Bif

244 ew source of oligosaccharides with potential prebiotic properties.

245 ts preserved the FOS content maintaining the prebiotic property of the juice.

246 Gels are interesting prebiotic reaction media, combining heterogeneous and ho

247 ydrogels offer a potential strategy by which prebiotic reactions can be promoted using simple, prebio

248 This emerging sequence of prebiotic reactions could have set the stage for the adv

249 However, compatible prebiotic reactions for the synthesis of complementary (

250 While prebiotic reactions from the rTCA cycle were accomplishe

251 ight have been available on early Earth from prebiotic reactions, with the goal of making the model l

252 The accumulation of phosphate and other prebiotic reagents at concentration and pH levels releva

253 Meta-analyses indicated that prebiotics reduce C-reactive protein (CRP) [standardized

254 ivity) function poorly as templates in model prebiotic RNA synthesis reactions, raising the question

255 rylation of 2-thiouridine-an intermediate of prebiotic RNA synthesis.

256 emerged as a plausible structural element in prebiotic RNAs.

257 Efforts to decipher the prebiotic roots of metabolic pathways have focused on re

258 wledge base for studying the biochemical and prebiotic significance of RNA 2-5-linkages.

259 00; P = 0.05) and by non-inulin-type fructan prebiotics (SMD: -0.34; 95% CI: -0.66, -0.01; P = 0.04),

260 Prebiotic soluble fibers are fermented by beneficial bac

261 Fourteen of 29 prebiotic studies and 13 of 26 synbiotic studies reporte

262 Nurturing a beneficial gut microbiome with prebiotics, such as fructo-oligosaccharides (FOS) and ga

263 043).Independent of other lifestyle changes, prebiotic supplementation in children with overweight an

264 ldren are limited.We examined the effects of prebiotic supplementation on appetite control and energy

265 Compared with placebo, prebiotic supplementation significantly reduced energy i

266 ent-to-treat analysis, there was a trend for prebiotic supplementation to reduce BMI z score to a gre

267 We discuss how probiotics, prebiotics, synbiotic, fecal microbiota transfer, polyph

268 ation and pH levels relevant to experimental prebiotic syntheses of key biomolecules is a compelling

269 Therefore, finding plausible prebiotic syntheses of potentially ancestral noncanonica

270 Moreover, the prebiotic syntheses of pyrimidine and purine nucleotides

271 To support these claims, computer-predicted, prebiotic syntheses of several biotic molecules as well

272 his research has focused on finding possible prebiotic syntheses of the four canonical nucleotides of

273 of RNA and DNA are generally centred on the prebiotic synthesis of a pristine system (pre-RNA or RNA

274 We now report a high-yielding, prebiotic synthesis of cysteine peptides.

275 However, it is likely that the prebiotic synthesis of ribonucleotides was accompanied b

276 Our synthesis uses key intermediates in the prebiotic synthesis of the canonical pyrimidine ribonucl

277 tely stereo-, regio- and furanosyl-selective prebiotic synthesis of the purine deoxyribonucleosides:

278 oxazoline as a potential intermediate in the prebiotic synthesis of the pyrimidine nucleotides with r

279 trol might have made the initial pathways to prebiotic systems evolution more intricate, but were sur

280 h ribozyme catalysis, it remains unclear how prebiotic systems generated and sustained pools of activ

281 This study tested if stress and/or dietary prebiotics (Test diet) alter the fecal metabolome; and e

282 se, mannooligosaccharides (MOS) are emerging prebiotics that have characteristic potential bio-active

283 ns (ginsenoside-Rb3 and ginsenoside-Rd) - as prebiotics - that effectively reinstated the dysbiotic-g

284 s obtained by GC-FID for products containing prebiotics, the content of FOS, GOS and GOS/FOS was in t

285 le for Mg(2+) supplementation as a potential prebiotic to promote establishment of oral health-associ

286 chobiotics be expanded beyond probiotics and prebiotics to include other means of influencing the mic

287 Also, the addition of prebiotics to MNPs is a promising approach to mitigate t

288 RCTs that compared prebiotics to placebo in adults with IBS or other FBDs w

289 owever, little is known about the ability of prebiotics to specifically modify gut microbiota in chil

290 e data strongly suggest a beneficial role of prebiotic treatment for stress-related behaviors.

291 Here we tested whether chronic prebiotic treatment modifies behavior across domains rel

292 Variations in prebiotic type and dose impacted symptom improvement or

293 ossible beneficial commensals, confirmed the prebiotic value of these xylooligosaccharides.

294 an experimental study on the permeability of prebiotic vesicle membranes composed of binary lipid mix

295 mation of long oligonucleotides inside model prebiotic vesicles, which suggests a potential route to

296 spring from mothers that received GOS/inulin prebiotics were protected against food allergies and dis

297 We expand this definition to encompass prebiotics, which enhance the growth of beneficial gut b

298 extrapolate back from extant biology to the prebiotic world, one must acknowledge the critical impor

299 have favored them as building blocks in the prebiotic world.

300 mer over the other might have emerged from a prebiotic world.