ライフサイエンスコーパス: preinitiation complex

1 oprecipitated, and OGT is a component of the preinitiation complex.

2 e context of a fully assembled transcription preinitiation complex.

3 polymerase II occurs during assembly of the preinitiation complex.

4 preliminary picture of the RNA polymerase II preinitiation complex.

5 of the mRNA-unwinding machinery to the 43 S preinitiation complex.

6 en complex results in destabilization of the preinitiation complex.

7 that it involves alterations within the 48S preinitiation complex.

8 es and AUG act coordinately to stabilize the preinitiation complex.

9 binding protein and TFIID, components of the preinitiation complex.

10 hat modulate the binding of mRNA to the 43 S preinitiation complex.

11 e II holoenzyme and DNA, for assembly of the preinitiation complex.

12 ritical for assembly of TFIID and the pol II preinitiation complex.

13 directed reorganization in a transcriptional preinitiation complex.

14 n to direct appropriate assembly of the URA1 preinitiation complex.

15 ongation, or by the inability to establish a preinitiation complex.

16 osphorylation of ribosomal protein S6 on the preinitiation complex.

17 ing site overlaps with that of TFIIIB in the preinitiation complex.

18 ion of the RNA polymerase II transcriptional preinitiation complex.

19 ormation of the RNA polymerase II-containing preinitiation complex.

20 D initiates formation of the transcriptional preinitiation complex.

21 factor 3f, a repressive component in the 43S preinitiation complex.

22 AUG-dependent dissociation of eIF1 from the preinitiation complex.

23 g eIF5-promoted hydrolysis of GTP in the 40S preinitiation complex.

24 s crucial for the assembly of the eukaryotic preinitiation complex.

25 is is released upon AUG selection by the 40S preinitiation complex.

26 mitting transcriptional activators to form a preinitiation complex.

27 complex and RNA polymerase II to create the preinitiation complex.

28 embly of the RNA polymerase II transcription preinitiation complex.

29 itical for the production of functional 40 S preinitiation complex.

30 R079c-a, as a potential new component of the preinitiation complex.

31 dditionally requires a fully assembled viral preinitiation complex.

32 -Rrn3 complex to the rDNA or stabilizing the preinitiation complex.

33 ing rapid promoter escape of Pol II from the preinitiation complex.

34 t to the closed conformation in the scanning preinitiation complex.

35 that required Beclin1, but not the autophagy preinitiation complex.

36 ion initiation begins with assembly of a 43S preinitiation complex.

37 own that it is a functional component of the preinitiation complex.

38 aggregates that contain stalled translation preinitiation complexes.

39 ted region of mRNA by scanning ribosomal 43S preinitiation complexes.

40 regulatory functions in protein translation preinitiation complexes.

41 eads to assembly of distinct transcriptional preinitiation complexes.

42 bly of archaeal and eukaryotic transcription preinitiation complexes.

43 vo and reduces 40S-binding of eIF3 to native preinitiation complexes.

44 ctors, and RPL41A mRNA to native 43S and 48S preinitiation complexes.

45 for U6 transcription and for assembly of U6 preinitiation complexes.

46 e, both Ded1 and Gle1 affect the assembly of preinitiation complexes.

47 uitment and frequent reutilization of stable preinitiation complexes.

48 on by controlling the assembly of functional preinitiation complexes.

49 inhibition of the assembly of transcription preinitiation complexes.

50 tion factors eIF1, eIF1A and eIF3 in the 40S preinitiation complex (40S.eIF1.eIF1A.eIF3.Met-tRNA(i).e

51 lity, the hydrolysis of GTP bound to the 40S preinitiation complex (40S.Met-tRNA(i).eIF2.GTP), promot

52 g eukaryotic translation initiation, the 43S preinitiation complex (43S PIC), consisting of the 40S r

53 s that a structural rearrangement in the 43S preinitiation complex activates it to become fully compe

54 Phosphorylation of components of the preinitiation complex activates replication and prevents

55 Thus, the eIF3 preinitiation complex acts as a scaffold to coordinate a

56 c1Delta mutation affects the assembly of the preinitiation complex after osmotic shock, it does not a

57 kinetic dissection of the transition from a preinitiation complex after start codon recognition to t

58 that nucleates the assembly of transcription preinitiation complexes, also independently interacts wi

59 To study TBP functions in preinitiation complex and other complexes, we generated

60 gene-specific transcription factors with the preinitiation complex and RNA polymerase II.

61 f mRNA and stimulates recruitment of the 43S preinitiation complex and subsequent scanning to the ini

62 dge about the architecture of the KSHV viral preinitiation complex and suggests that it functions as

63 anding the architecture of the mammalian 43S preinitiation complex and the complex of eIF3, 40S, and

64 4me3 that leads to assembly of transcription preinitiation complex and transcriptional activation.

65 , for Mediator-dependent assembly of a basal preinitiation complex and, more important, identify a st

66 P1-NTD is required for efficient assembly of preinitiation complexes and also regulates the selection

67 rt site (TSS) selection reflect diversity of preinitiation complexes and can impact on post-transcrip

68 3j/HCR1 remains associated with the scanning preinitiation complexes and does not dissociate from the

69 -a is a bona fide component of polymerase II preinitiation complexes and investigate its role in tran

70 x and, consequently, the assembly of the 48S preinitiation complexes and protein synthesis.

71 ble binding of at least some mRNAs to native preinitiation complexes and that eIF4G has a rate-limiti

72 t the recruitment, assembly, and progress of preinitiation complexes and the ribosome under many phys

73 a model whereby BRCA1 stabilizes productive preinitiation complexes and thus stimulates transcriptio

74 apoptosis, the assembly of RNA polymerase II preinitiation complexes and WNT signalling.

75 is a central component of the transcription preinitiation complex, and its occupancy at a promoter i

76 core promoter of RNR3 is sufficient to drive preinitiation complex assembly and activate transcriptio

77 0S binding of eIF3 and is needed for optimal preinitiation complex assembly and AUG recognition in vi

78 EAT domain is a critical nucleation core for preinitiation complex assembly and function.

79 ontrol global gene expression in eukaryotes: preinitiation complex assembly and polymerase pausing.

80 re, a TFIIB-related protein is implicated in preinitiation complex assembly and postpolymerase recrui

81 ations of these results for the mechanism of preinitiation complex assembly and promoter melting.

82 y by the activator Gcn4p but is dependent on preinitiation complex assembly and Ser5 carboxy-terminal

83 n factor 4F (eIF4F) complex and promotes 48S preinitiation complex assembly and start-site scanning o

84 oter chromatin remodeling from transcription preinitiation complex assembly and suggest the existence

85 sis coupled with native gel electrophoresis, preinitiation complex assembly assays, and translation i

86 8p and H3-K4 methylation are dispensable for preinitiation complex assembly at the core promoters of

87 ability of chromatin-bound Gcn4 to stimulate preinitiation complex assembly at the promoter.

88 inct mechanisms for ribosome recruitment and preinitiation complex assembly between the two processes

89 can be used to learn how different modes of preinitiation complex assembly impact transcriptional ac

90 However, it is unknown how preinitiation complex assembly is coordinated with chrom

91 required for activators to stimulate Pol II preinitiation complex assembly on an associated promoter

92 with the MED23 Mediator subunit, stimulating preinitiation complex assembly on early viral promoters

93 om the TAF1-TFIID complex upon completion of preinitiation complex assembly, allowing transcription t

94 ated GR attenuated ISGF3 promoter occupancy, preinitiation complex assembly, and ISG expression.

95 t Mdm30p is dispensable for formation of the preinitiation complex assembly, association of elongatin

96 inhibiting an essential function of TFIIF in preinitiation complex assembly, but also that Mediator c

97 rent steps in transcription before and after preinitiation complex assembly.

98 sferase-independent function at the level of preinitiation complex assembly.

99 ion elongation factor TFIIS functions during preinitiation complex assembly.

100 h, which allows TFIID binding and subsequent preinitiation complex assembly.

101 te Pol II initiation at a step subsequent to preinitiation complex assembly.

102 MFC), an important intermediate for the 43 S preinitiation complex assembly.

103 T1/Cdk9 inhibits PGC-1 promoter activity and preinitiation complex assembly.

104 ding to core promoter elements and directing preinitiation complex assembly.

105 lucosaminidase) blocked transcription during preinitiation complex assembly.

106 g transcriptional activators and facilitates preinitiation-complex assembly and transcription.

107 Consistent with this finding, Mediator and preinitiation complex association with SAGA-dependent pr

108 e present a cryoEM reconstruction of a yeast preinitiation complex at 4.0 A resolution with initiator

109 nally, we examined the assembly of the viral preinitiation complex at late gene promoters and found t

110 the cap-binding complex, eIF4F, anchors the preinitiation complex at the 5' end of mRNAs and regulat

111 on network is essential for formation of the preinitiation complex at the core promoter to initiate t

112 needed to assemble a transcription-competent preinitiation complex at the promoter.

113 olymerase II, nucleating the assembly of the preinitiation complex at the transcription start site.

114 hich is thought to stabilize properly formed preinitiation complexes at the correct start codon.

115 CDK8 module are specifically recruited into preinitiation complexes at the TR target gene type I dei

116 like unexpressed genes without transcription-preinitiation complexes at their promoters, expressed ge

117 ation of most eukaryotic mRNAs occurs when a preinitiation complex binds to the 5' cap, scans the mRN

118 s bind immediately downstream of the Pol III preinitiation complex but are not required for Pol III r

119 ire the preloading of RNA polymerase II or a preinitiation complex but instead depends upon the Gcn5

120 nal initiation is the recruitment of the 43S preinitiation complex by the cap-binding complex [eukary

121 rug influences the assembly and stability of preinitiation complexes by targeting the interaction bet

122 This suggests that functional preinitiation complexes can contain Mot1 instead of TFII

123 of eIF1 was identified, interfaces to other preinitiation complex components and their relevance to

124 caffold for the dynamic associations of many preinitiation complex components, including the growth-r

125 et out to fine-map a small viral replication preinitiation complex composed of two protein dimers bou

126 First, 43S preinitiation complexes comprising 40S ribosomal subunit

127 e of mediating assembly of the transcription preinitiation complex containing RNA polymerase II.

128 iation in Archaea requires the assembly of a preinitiation complex containing the TATA- box binding p

129 nslation initiation factor (eIF)3 enable 43S preinitiation complexes containing eIF3 and eIF2-GTP-Met

130 binding to Adr1 at promoters that contain a preinitiation complex, demonstrating that Bmh-mediated i

131 gly, the initiation codon recognition by 43S preinitiation complex during EXT2 translation is suppres

132 TFEalpha/beta stabilises the preinitiation complex, enhances DNA melting, and stimula

133 omoters, expressed genes or genes containing preinitiation complexes exhibit characteristic nucleosom

134 initiation involves the assembly of the 48S preinitiation complex, followed by joining of the 60S ri

135 able to scan template DNA downstream of the preinitiation complex for acceptable start sites.

136 IID (TFIID), which nucleates assembly of the preinitiation complex for transcription by RNA polymeras

137 The pathways by which preinitiation complexes form, and how this impacts trans

138 reagents, their effect on transcription and preinitiation complex formation and discuss their potent

139 ter escape are linked to stronger effects on preinitiation complex formation and transcription, sugge

140 on it alters chromatin structure to increase preinitiation complex formation and transcription.

141 omote dephosphorylation of Ser5 to stimulate preinitiation complex formation and, later, to inhibit e

142 ts with promoter conformation and downstream preinitiation complex formation and/or function.

143 associated factors (TAFs), is essential for preinitiation complex formation at ribosomal RNA gene pr

144 rved cis elements, the TFIID complex directs preinitiation complex formation at specific sites in cor

145 e context-dependent Saccharomyces cerevisiae preinitiation complex formation at the HIS4 promoter rec

146 egative regulation of transcription, correct preinitiation complex formation in basal and activated t

147 Furthermore, Tup1 repressed RNR3 and blocked preinitiation complex formation in the Deltaisw2 mutant,

148 ubunit, in Pol I recruitment and, therefore, preinitiation complex formation in vivo.

149 opose a model of stochastic enhanceosome and preinitiation complex formation that incorporates transc

150 anning sequences downstream from the site of preinitiation complex formation, a process that involves

151 ARG1 is independent of the TATA element and preinitiation complex formation, whereas efficient recru

152 osmoresponse gene transcription by enhancing preinitiation complex formation.

153 histone acetylation) at a step subsequent to preinitiation complex formation.

154 alterations and subsequent RNA polymerase II preinitiation complex formation.

155 ily blocks steps downstream of transcription preinitiation complex formation.

156 of TATA box genes appear to be controlled at preinitiation complex formation.

157 We also determined the structure of the 48S preinitiation complex formed by Nsp1, 40S, and the crick

158 arts of the IRES RNA change structure as the preinitiation complex forms.

159 scription factor IIB and dissociation of the preinitiation complex from the major promoter.

160 nesis requires SWI/SNF enzymes to facilitate preinitiation complex function.

161 SNF affects recruitment of components of the preinitiation complex in a promoter-specific manner to m

162 important role for RLI1 in assembly of 43 S preinitiation complexes in vivo.

163 neral transcription factors that make up the preinitiation complex, including Pol II, but there was n

164 air GCN4 translational control by disrupting preinitiation complex interactions.

165 onal changes that mark the transition of 30S preinitiation complex into elongation competent 70S comp

166 n by BRCA1 is that the ubiquitination of the preinitiation complex is not targeting proteins for degr

167 se that the overall structure of the RNAP II preinitiation complex is similar in all eukaryotes and i

168 TOR), and appears to represent an incomplete preinitiation complex lacking several subunits.

169 ng the formation of stable RNA polymerase II preinitiation complexes leading to transcription initiat

170 rs that include a complete RNA polymerase II preinitiation complex, MED1 and CDK9.

171 lating the assembly of the 48S translational preinitiation complex mediated by the p27 IRES element.

172 d the AdMLP suggests that Rep78/68 alter the preinitiation complex of RNA polymerase II transcription

173 ation of mda-7/IL-24 mRNA, activation of the preinitiation complex of the translational machinery in

174 he other factors necessary for assembly of a preinitiation complex on naked DNA.

175 erentially affects the assembly of ribosomal preinitiation complexes on different cellular and viral

176 PSEA, DmSNAPc establishes RNA polymerase II preinitiation complexes on U1 to U5 promoters but RNA po

177 on U1 to U5 promoters but RNA polymerase III preinitiation complexes on U6 promoters.

178 We show that NUFIP is associated with preinitiation complexes, open transcription complexes, a

179 cription by interfering with assembly of the preinitiation complex or by blocking transcription initi

180 regulate later stages in the assembly of the preinitiation complex or facilitate multiple rounds of p

181 However, RNA pol III bound to preinitiation complexes or in elongation complexes is pr

182 se TBP derivatives in isolated transcription preinitiation complexes or in living cells reveals physi

183 roteins, but not the conventional autophagic preinitiation complex, or adaptor protein-3 (AP-3).

184 ge number of promoters assemble into partial preinitiation complexes (partial PICs), containing TFIIA

185 Dissociation of eIF1 from the preinitiation complex (PIC) allows release of phosphate

186 omain (eIF5-CTD) directly links eIF4G to the preinitiation complex (PIC) and enhances mRNA binding.

187 of melted DNA separately associated with the preinitiation complex (PIC) and the adjacent paused comp

188 anslation initiation factor eIF1A stimulates preinitiation complex (PIC) assembly and scanning, but t

189 ription factor TFIIB plays a central role in preinitiation complex (PIC) assembly and the recruitment

190 SIR-mediated silencing is permissive to both preinitiation complex (PIC) assembly and transcription i

191 e GAL1 UAS, and facilitates formation of the preinitiation complex (PIC) assembly at the GAL1 promote

192 he steps leading to chromatin remodeling and preinitiation complex (PIC) assembly differ significantl

193 e Ded1 unwinding activity and stimulation of preinitiation complex (PIC) assembly in vitro.

194 A "step-wise" preinitiation complex (PIC) assembly model has been sugg

195 (PRC1) inhibits activated RNA polymerase II preinitiation complex (PIC) assembly using immobilized H

196 FIIF are both required for RNA polymerase II preinitiation complex (PIC) assembly, but their roles at

197 he structure of transcription factors (TFs), Preinitiation Complex (PIC) assembly, RNA polymerase II

198 ween VP16-mediated chromatin acetylation and preinitiation complex (PIC) assembly.

199 nscription factor TFIID, which might promote preinitiation complex (PIC) assembly.

200 events PESE-dependent Pol II recruitment and preinitiation complex (PIC) assembly.

201 anscription initiation and play key roles in preinitiation complex (PIC) assembly.

202 ies of highly regulated steps: assembly of a preinitiation complex (PIC) at the promoter nucleated by

203 s of highly regulated steps: assembly of the preinitiation complex (PIC) at the promoter, initiation,

204 vating protein complex, form a transcription preinitiation complex (PIC) at the spliced leader (SL) R

205 olving mRNA secondary structures that impede preinitiation complex (PIC) attachment to mRNA or scanni

206 The eukaryotic 43S preinitiation complex (PIC) bearing Met-tRNAi(Met) in a

207 defective for interaction with polymerase II preinitiation complex (PIC) components and other regulat

208 The resulting complete pol II transcription preinitiation complex (PIC) contained equimolar amounts

209 In translation initiation, a 43S preinitiation complex (PIC) containing eIF1 and a ternar

210 steps in transcription initiation including preinitiation complex (PIC) formation and start site sel

211 ans is regulated in several steps, including preinitiation complex (PIC) formation, initiation, Pol I

212 III dependent transcription before and after preinitiation complex (PIC) formation.

213 s p53-dependent transcription by stimulating preinitiation complex (PIC) formation; (2) H3K4me3, thro

214 scription commences with the assembly of the Preinitiation Complex (PIC) from a plethora of proteins

215 ecognition triggers rearrangement of the 48S preinitiation complex (PIC) from an open conformation to

216 work implicated eIF5 in rearrangement of the preinitiation complex (PIC) from an open, scanning confo

217 ensus motif for the positioning of the human preinitiation complex (PIC) has been identified.

218 complexes remove the -1 nucleosome after the preinitiation complex (PIC) has partially assembled, but

219 ferences of the key components of eukaryotic preinitiation complex (PIC) have been recently measured

220 promoting ATP-dependent dissociation of the preinitiation complex (PIC) into the Scaffold complex.

221 don in an mRNA by the eukaryotic translation preinitiation complex (PIC) is essential for proper gene

222 The translation preinitiation complex (PIC) is thought to assume an open

223 1), eIF1A, eIF3, and eIF5, and the resulting preinitiation complex (PIC) joins the 5' end of mRNA pre

224 The formation of a stable 43 S preinitiation complex (PIC) must occur to enable success

225 that a reduced affinity of eIF3j for the 43S preinitiation complex (PIC) occurs on eIF4F-dependent mR

226 The assembly of the preinitiation complex (PIC) occurs upstream of the +1 nu

227 ns with the assembly of an RNA polymerase II preinitiation complex (PIC) on the promoter.

228 oactivators are required for assembly of the preinitiation complex (PIC) or for subsequent steps in t

229 structures that impede attachment of the 43S preinitiation complex (PIC) or scanning.

230 ires the assembly at the promoter of a large preinitiation complex (PIC) that includes RNA polymerase

231 inately recruit RNA polymerase II and form a preinitiation complex (PIC) to activate MyoD transcripti

232 ces cerevisiae that allows conversion of the preinitiation complex (PIC) to bona fide initially trans

233 as been implicated in attachment of the 43 S preinitiation complex (PIC) to mRNAs and scanning to the

234 ve reconstituted mRNA recruitment to the 43S preinitiation complex (PIC) using purified S. cerevisiae

235 e of a 33-protein, 1.5-MDa RNA polymerase II preinitiation complex (PIC) was determined by cryo-EM an

236 nucleates the assembly of the transcription preinitiation complex (PIC), and although TBP can bind p

237 x and its role, along with components of the preinitiation complex (PIC), in histone eviction at indu

238 s H2A and H2B, Nap1p, and a component of the preinitiation complex (PIC), TBP.

239 formation and function of the promoter-bound preinitiation complex (PIC), which consists of RNA polym

240 ted steps in the assembly of a transcription preinitiation complex (PIC).

241 the RNA polymerase II (Pol II) transcription preinitiation complex (PIC).

242 with RNA polymerase (Pol) II as part of the preinitiation complex (PIC).

243 inhibits the assembly and the function of a preinitiation complex (PIC).

244 ption factors and promoter DNA in a 'closed' preinitiation complex (PIC); unwinding of about 15 base

245 if32 CTD that impair mRNA recruitment by 43S preinitiation complexes (PICs) and confer phenotypes ind

246 Transcription preinitiation complexes (PICs) are vital assemblies whos

247 o determine how Mot1 affects the assembly of preinitiation complexes (PICs) at Mot1-controlled promot

248 manner suggesting incomplete assembly of 48S preinitiation complexes (PICs) at upstream AUG codons in

249 bly of RNA polymerase (Pol) II transcription preinitiation complexes (PICs) have been well establishe

250 eomic analysis of RNA polymerase II (RNApII) preinitiation complexes (PICs) identified Sub1 and the r

251 However, pol II preinitiation complexes (PICs) lose the ability to synth

252 The accumulation of stalled translation preinitiation complexes (PICs) mediates the condensation

253 (MuDPIT) and immunoblot analyses of purified preinitiation complexes (PICs) revealed the recruitment

254 n by facilitating the recruitment of RNAP II preinitiation complexes (PICs) to the promoter regions o

255 face that is required for rapid formation of preinitiation complexes (PICs) was identified on the N-t

256 apid, TATA box-dependent assembly of RNAP II preinitiation complexes (PICs), but permits few rounds o

257 rprisingly, when Gdown1 is added to complete preinitiation complexes (PICs), it does not inhibit init

258 mes can lead to queuing/stacking of scanning preinitiation complexes (PICs), preferentially enhancing

259 isolated that affect either the assembly of preinitiation complexes (PICs), scanning for AUG, or bot

260 ociation and P(i) release from reconstituted preinitiation complexes (PICs), whereas a hyperaccuracy

261 nhibition, polysome disassembly releases 48S preinitiation complexes (PICs).

262 ngation, but such information is lacking for preinitiation complexes (PICs).

263 ometric screen of RNA polymerase II (Pol II) preinitiation complexes (PICs).

264 complex [TC] with eIF2-GTP) to reconstituted preinitiation complexes (PICs).

265 tiation of DNA synthesis from each origin, a preinitiation complex (pre-IC) containing Cdc45 and othe

266 and a core component of the DNA replication preinitiation complex (pre-IC), and that the TICRR-TopBP

267 BRCA1 ubiquitinates the transcriptional preinitiation complex, preventing stable association of

268 The "preloading" of T-RS into HIV-1 preinitiation complexes prevents the entry of active Tat

269 he involvement of MED25 for fully functional preinitiation complex recruitment and transcriptional ou

270 -depth characterization of RNA polymerase II preinitiation complexes remains an important and challen

271 scription by blocking the recruitment of the preinitiation complex (RNA polymerase II and TFIIB) to t

272 oter recruitment of poised RNA polymerase II preinitiation complex (RNAPII PIC), which enhances futur

273 r transcription in requiring a virus-encoded preinitiation complex that binds to TATT motifs unique t

274 nd eIF1A promote an open, scanning-competent preinitiation complex that closes upon start codon recog

275 rred, and the activators recruited a partial preinitiation complex that included RNA polymerase II.

276 slation initiation in eukaryotes occurs in a preinitiation complex that includes small ribosomal subu

277 dues of eIF1 disrupts a critical link to the preinitiation complex that suppresses eIF1 release befor

278 information for the papillomavirus E1E2-ori preinitiation complex that would otherwise have been har

279 oplasmic aggregates of stalled translational preinitiation complexes that accumulate during stress.

280 s granules (SGs) contain stalled translation preinitiation complexes that are assembled into discrete

281 /eIF2/GTP binds to 40S subunits yielding 43S preinitiation complexes that attach to the 5'-terminal r

282 n factors and Pol II to assemble on DNA into preinitiation complexes that can begin RNA synthesis upo

283 s impair the integrity of scanning-competent preinitiation complex, thereby altering the 40 S subunit

284 e the interaction with the components of the preinitiation complex, thereby inhibiting its function a

285 use the proteasome to target transcriptional preinitiation complexes, thus minimizing transcriptional

286 specifically removes eIF4G1 from translation preinitiation complexes, thus removing eIF4G1 from the t

287 .eIF2.GTP) and the subsequent binding of the preinitiation complex to eIF4F bound at the 5'-cap struc

288 ription by inhibiting the recruitment of the preinitiation complex to the c-jun promoter.

289 o the efficient recruitment of transcription preinitiation complexes to active promoters.

290 on codon selection and enables mammalian 43S preinitiation complexes to discriminate against AUG codo

291 with the presence of stalled 48S translation preinitiation complexes to persist throughout infection.

292 ruses have been determined to encode a viral preinitiation complex (vPIC) that mediates late gene exp

293 method to analyze a yeast RNA polymerase II preinitiation complex, we identified a new 8-kDa protein

294 template assays in which activator-recruited preinitiation complexes were allowed to undergo one cycl

295 4 acidic activation domains in transcription preinitiation complexes were identified by site-specific

296 of EIF1AX, a component of the translational preinitiation complex, were markedly enriched in PDTCs a

297 lymerase II (Pol II) with the promoter-bound preinitiation complex, whereas Brf1 and Brf2 are involve

298 ly bind to the 40S subunit, yielding the 43S preinitiation complex, which is ready to attach to messe

299 ted to stimulate attachment of 43S ribosomal preinitiation complexes, which then scan to the initiati

300 Initiation involves direct attachment of 43S preinitiation complexes within a short window at or imme