ライフサイエンスコーパス: prelimbic

1 ver, the respective contribution of distinct prelimbic afferents to the temporal and contextual compo

2 xtensive striatal projection fields from the prelimbic and anterior cingulate areas, which partly ove

3 lly regulated genes, as well as variation in prelimbic and anterior cingulate cortical thickness at p

4 e midfrontal cortex in humans and within the prelimbic and anterior cingulate regions of the MFC in r

5 eactivity in all layers, particularly in the prelimbic and anterior cingulate subregions.

6 ist challenge, which was most significant in prelimbic and anterior cingulate subregions.

7 L) directly into the dorsomedial PFC (dorsal prelimbic and dorsal anterior cingulate cortex), the ven

8 Single neuron activity was recorded from the prelimbic and infralimbic areas of the medial prefrontal

9 Stereological analyses of the ventral mPFC (prelimbic and infralimbic areas) and the BLN were perfor

10 er V-VI pyramidal neurons in slices of mouse prelimbic and infralimbic cortex were studied.

11 These data indicate a role for mPFC (prelimbic and infralimbic cortex) in the formation of a

12 neuronal activity in homolog regions (i.e., prelimbic and infralimbic cortices) changes during fear

13 sus ventral aspects of mPFC, centered in the prelimbic and infralimbic fields, respectively, on acute

14 tion in response to the exposed music in the prelimbic and infralimbic medial prefrontal cortex only

15 , a GABA agonist, was used to inactivate the prelimbic and infralimbic mPFC subdivisions (400 ng in 2

16 number of Fos-ir(+) and Fos-ir(-) neurons in prelimbic and infralimbic mPFC.

17 sed expression of a plasticity marker in the prelimbic and infralimbic prefrontal cortices, the orbit

18 labelled neurons were exclusively located in prelimbic and infralimbic regions in layers V and VI, af

19 ters spontaneous single-unit activity in the prelimbic and infralimbic subdivisions of the mPFC in be

20 election relies on top-down control from the prelimbic and orbitofrontal cortices over striatal activ

21 redominantly inhibitory and emanate from the prelimbic and/or dorsal anterior cingulate cortical fiel

22 on and reward processing, i.e., infralimbic, prelimbic, and anterior cingulate cortices, amygdala, an

23 n the medial prefrontal cortex (infralimbic, prelimbic, and cingulate cortex) and dorsolateral striat

24 ons to 10 target nuclei: anterior cingulate, prelimbic, and infralimbic cortex; nucleus accumbens cor

25 ith dorsal (encompassing anterior cingulate, prelimbic, and infralimbic cortices) or ventral (encompa

26 ivisions of the mPFC, i.e., the infralimbic, prelimbic, anterior cingulate and medial agranular corti

27 We showed that (1) the infralimbic, prelimbic, anterior cingulate cortices distribute heavil

28 ial prefrontal cortex (mPFC) centered on the prelimbic area (Brodmann's area 32), at five different i

29 fast spiking interneurons (PV+ FSIs) in the prelimbic area (PrL) of the mPFC in mice.

30 a 25 and area 32pl, which corresponds to the prelimbic area 32 in Brodmann's monkey brain map, caudal

31 The prelimbic area and the rostral part of the anterior cing

32 In the medial prefrontal cortex, the prelimbic area is emerging as a major modulator of fear

33 Pyramidal neurons in the prelimbic area of medial prefrontal cortex were selected

34 of pyramidal neuron apical dendrites in the prelimbic area of the medial prefrontal cortex (mPFC).

35 Pyramidal neurons in the prelimbic area of the mPFC were selected for intracellul

36 r area of the prefrontal cortex (PFC) or the prelimbic area of the PFC.

37 visually-guided version was dependent on the prelimbic area.

38 ne inactivation of the agranular insular and prelimbic areas.

39 Finally, stimulation and inhibition of the prelimbic-avBST pathway, respectively, decreased and inc

40 These data indicate that prelimbic BDNF is critical for consolidation of learned

41 he medial prefrontal cortex (infralimbic and prelimbic) but not the anterior cingulate and M1 motor c

42 mPFC lesions of prelimbic cortex (Brodmann's Area 32) retarded EB condit

43 bgenual anterior cingulate in the human), or prelimbic cortex (midventral anterior cingulate).

44 l hippocampal (VH) neurons projecting to the prelimbic cortex (PL) and basal amygdala (BA) after the

45 In rats, inactivation of the prelimbic cortex (PL) attenuates renewal.

46 Prelimbic cortex (PL) projections to nucleus accumbens c

47 statement of cocaine- and sucrose-seeking in prelimbic cortex (PL), infralimbic cortex (IL), BLA, and

48 muscimol to pharmacologically inactivate the prelimbic cortex (PL), infralimbic cortex (IL), ventral

49 equires sustained cue-elicited firing in the prelimbic cortex (PL).

50 ttenuation of inhibitory transmission in the prelimbic cortex (PL).

51 Although the prelimbic cortex (PL, part of medial prefrontal cortex)

52 strongly activated neuronal ensembles in rat prelimbic cortex (PLC) and assess altered intrinsic exci

53 DAT blockade induced pMeCP2 in the prelimbic cortex (PLC) and nucleus accumbens (NAc), wher

54 Fos-expressing layer V pyramidal neurons in prelimbic cortex (PLC) of FosGFP-transgenic rats, we fou

55 trophysiology to investigate the role of the prelimbic cortex (PrL) in this process.

56 ue-Dawley rats, whether BLA activity enables prelimbic cortex (PrL) interactions with the anterior in

57 The prelimbic cortex (PrL) is heavily interconnected with se

58 c acid (GABA) neurotransmitter system in the prelimbic cortex (PrL) of adult mice.

59 stimulation of the neuronal pathway from the prelimbic cortex (PrL) to the paraventricular nucleus of

60 e observed as the oscillations in the dorsal prelimbic cortex (PrL) were smaller in magnitude than th

61 ocorticolimbic system: that is, the VTA, the prelimbic cortex (PrL), and infralimbic cortex of medial

62 HT receptors, in layer II/III neurons of the prelimbic cortex (PrL), as well as depression-like behav

63 ediate early genes (IEGs; e.g. c-fos) in the prelimbic cortex (PrL), basolateral amygdala complex (BL

64 and dopaminergic abnormalities in the adult prelimbic cortex (PrL-C).

65 naling in layer 5/6 pyramidal neurons of the prelimbic cortex (PrLC) and involved a D(1)/(5) dopamine

66 Theta and low-gamma synchrony in the prelimbic cortex (PrlC) is impaired in Disc1 mice and in

67 c-fos mRNA was injected into the infralimbic/prelimbic cortex 12 or 72 hr before the acquisition sess

68 cal field potential pattern generated in the prelimbic cortex and associated with goal-directed behav

69 cted to specific forebrain areas such as the prelimbic cortex and the accumbens nucleus.

70 ted drug seeking by depending on activity in prelimbic cortex and the basolateral amygdala.

71 sion group) or vehicle (sham group) into the prelimbic cortex and were later tested for acquisition,

72 naling in layer 5/6 pyramidal neurons of the prelimbic cortex appears to represent an early adaptatio

73 Our findings show that the prelimbic cortex can generate oscillatory patterns that

74 ons in S1, but normal infralimbic cortex and prelimbic cortex dendritic arborization.

75 on of a protein synthesis inhibitor into the prelimbic cortex did not affect any measure of acquisiti

76 isition, showing that during acquisition the prelimbic cortex does not mediate postsession consolidat

77 Our results show a marked reduction in prelimbic cortex excitability in compulsive cocaine-seek

78 Optogenetic silencing of the prelimbic cortex exclusively timed to encounters of no r

79 We suggest that the prelimbic cortex exerts direct influence over medium spi

80 Finally, inhibition of the prelimbic cortex immediately after unreinforced lever pr

81 l and central nuclei of the amygdala and the prelimbic cortex in both the Paired and Pavlovian groups

82 vestigating the potential involvement of the prelimbic cortex in instrumental acquisition, in which t

83 discussed in the context of the role of the prelimbic cortex in processing temporal information duri

84 ions between the ventral hippocampus and the prelimbic cortex in rodents or the dorsal anterior cingu

85 However, inactivation of the prelimbic cortex increased responding, suggesting that t

86 pulsive cocaine seeking, whereas optogenetic prelimbic cortex inhibition significantly increased comp

87 The prelimbic cortex is implicated in goal-directed learning

88 This finding suggests that the prelimbic cortex is involved in the incentive motivation

89 To determine whether the prelimbic cortex is necessary for cocaine-reinstated CPP

90 The prelimbic cortex is required for forming fear memories w

91 10 mg/kg, i.p.) was attenuated in rats with prelimbic cortex lesions relative to sham controls.

92 ex increased responding, suggesting that the prelimbic cortex mediates a form of inhibitory response

93 Furthermore, compensating for hypoactive prelimbic cortex neurons with in vivo optogenetic prelim

94 he spike-timing of identified neurons in the prelimbic cortex of anesthetized rats, and show that axo

95 ) reported that single cells recorded in the prelimbic cortex of rats during the acquisition of trace

96 The potential role of the prelimbic cortex of the rat in the acquisition of instru

97 al application of guanfacine into either the prelimbic cortex or the ventral tegmental area did not p

98 xtran amine deposits centered in the ventral prelimbic cortex revealed that, during this period, the

99 e-seeking rats, and that in vivo optogenetic prelimbic cortex stimulation decreased compulsive drug-s

100 mbic cortex neurons with in vivo optogenetic prelimbic cortex stimulation significantly prevented com

101 type Ca(2+) channels (LTCCs) in cells of the prelimbic cortex that project to the nucleus accumbens c

102 ojections from anterior cingulate cortex and prelimbic cortex to infralimbic cortex may be important

103 ent of the glutamatergic projection from the prelimbic cortex to NAcore is necessary to initiate the

104 olved and suggests that ketamine acts at the prelimbic cortex to sensitize neurons that project to an

105 ntextual and working-memory contributions of prelimbic cortex to the formation of a fear memory and d

106 f the D1 receptor agonist SKF-38393 into the prelimbic cortex was found to modulate incongruent trial

107 jections in the dorsal mPFC (centered in the prelimbic cortex) attenuated increments in restraint-ind

108 onist eticlopride into the NAcc (but not the prelimbic cortex) blocked the formation of a partner pre

109 t not the anterior cingulate cortex (ACC) or prelimbic cortex), reduced IL single-unit firing and bur

110 lpha and BDNF in the hypothalamus, amygdala, prelimbic cortex, and ventral hippocampus.

111 In some sites, e.g., prelimbic cortex, anterior cingulate cortex, and seconda

112 entral hippocampal neurons projecting to the prelimbic cortex, but not to the infralimbic cortex or b

113 rimary motor cortex, orbital frontal cortex, prelimbic cortex, dorsal lateral striatum, medial dorsal

114 ess exhibited reduced HDAC4 and HDAC5 in the prelimbic cortex, hippocampus, and striatum.

115 eir anatomical homologs, the infralimbic and prelimbic cortex, in rodents.

116 fusions of NaB into the infralimbic, but not prelimbic cortex, induced extinction enhancements.

117 umber of D1- or D2-expressing neurons in the prelimbic cortex, infralimbic cortex (IL), insula cortex

118 x, but had no effect on the dorsal striatum, prelimbic cortex, or ventral pallidum.

119 g correlates with dendritic spine density in prelimbic cortex, suggesting that new action-outcome lea

120 ly assumed that infralimbic cortex (ILC) and prelimbic cortex, two adjacent areas of the medial prefr

121 ic brain areas (nucleus accumbens, amygdala, prelimbic cortex, ventral hippocampus, and ventral tegme

122 of GABAergic chandelier cells (ChCs) in the prelimbic cortex, which innervate PCs at spike initiatio

123 ility of deep-layer pyramidal neurons in the prelimbic cortex, which was significantly more pronounce

124 Cs as opposed to BLAPCs and BLA neurons (the prelimbic cortex-BLA network).

125 No similar effect was seen in the prelimbic cortex.

126 nce following infusion of SKF-38393 into the prelimbic cortex.

127 oss in layer II/III pyramidal neurons of rat prelimbic cortex.

128 utamatergic afferents to the NAcore from the prelimbic cortex.

129 ation and its potential interaction with the prelimbic cortex.

130 s, whereas c-fos expression was decreased in prelimbic cortex.

131 ociated increase in dopamine turnover in the prelimbic cortex.

132 re and shell, anterior cingulate cortex, and prelimbic cortex.

133 rgeted GR knockdown to output neurons of the prelimbic cortex.

134 ction of candles was observed in the ventral prelimbic cortex.

135 areas we explored, including prefrontal and prelimbic cortex.

136 or inhibition of CB1 transmission within the prelimbic cortical (PLC) division of the mPFC bidirectio

137 Fasudil transiently reduces prelimbic cortical dendritic spine densities during a pe

138 on selection by augmenting the plasticity of prelimbic cortical dendritic spines during the formation

139 ly inhibited input to avBST from the rostral prelimbic cortical region of mPFC and observed concurren

140 neocortical knockout mouse, virally mediated prelimbic cortical-specific gene deletion, and pharmacol

141 rised of two subregions: the infralimbic and prelimbic cortices (ilPFC and plPFC).

142 t, lesions restricted to the infralimbic and prelimbic cortices have no effect on CAL but impair perf

143 ing the anterior cingulate, infralimbic, and prelimbic cortices impair CAL because of increased inter

144 cortex, including the anterior cingulate and prelimbic cortices, and the temporal cortex show robust

145 al cortex, which consists of infralimbic and prelimbic cortices, blocks recall of fear extinction, in

146 These include the infralimbic, prelimbic, dorsal agranular insular, and entorhinal cort

147 In contrast, prelimbic inactivation caused an apparent improvement in

148 sults contrast with findings indicating that prelimbic inactivation impairs behavioral flexibility du

149 gic pyramidal neurons of layer V/VI frontal (prelimbic, infralimbic) cortex (FC).

150 rat OFC (lateral and medial) and medial PFC (prelimbic, infralimbic, and anterior cingulate) on proba

151 f rat medial frontal cortex (MFC) (including prelimbic, infralimbic, and cingulate cortices) in effor

152 " pathway provides disynaptic input from the prelimbic, infralimbic, and orbital cortex to the ventra

153 urth, the BSTju provides light inputs to the prelimbic, infralimbic, and ventral CA1 cortical areas;

154 ial and ventral orbital, anterior cingulate, prelimbic, infralimbic, insular, perirhinal, and entorhi

155 This includes prelimbic, infralimbic, medial, ventrolateral and latera

156 Overall, these results suggest that the prelimbic-infralimbic areas are important for behavioral

157 These findings suggest that the prelimbic-infralimbic areas are involved in switching to

158 Infusions of 2% tetracaine into the prelimbic-infralimbic areas did not impair acquisition o

159 ved in the odor-place tests suggest that the prelimbic-infralimbic areas enable behavioral flexibilit

160 ent experiments investigated the role of the prelimbic-infralimbic areas in behavioral flexibility us

161 To investigate the role of the prelimbic-infralimbic areas in intramodal shifts (revers

162 To examine the role of the prelimbic-infralimbic areas in shifting strategies, rats

163 t study examined whether inactivation of the prelimbic-infralimbic areas or the dorsal anterior cingu

164 However, inactivation of the prelimbic-infralimbic areas, but not the dorsal anterior

165 ved a bilateral cannula implant aimed at the prelimbic-infralimbic areas.

166 Prelimbic-infralimbic cortex (PL-IL) and orbitofrontal c

167 regions [anterior cingulate cortex (ACC) and prelimbic-infralimbic cortex (PL-IL)] play in such decis

168 Prelimbic-infralimbic inactivation did impair learning w

169 Prelimbic-infralimbic inactivation did not impair acquis

170 Prelimbic-infralimbic inactivation did not impair place

171 The experiments examined the effects of prelimbic-infralimbic inactivation in rats on the acquis

172 Infusions of 2% tetracaine into the prelimbic-infralimbic or dorsal anterior cingulate areas

173 mplantation of a cannula aimed at either the prelimbic-infralimbic or dorsal anterior cingulate areas

174 originated from stimulation sites in ventral prelimbic/infralimbic cortex, and were significantly mor

175 memory in rats with bilateral mPFC lesions (prelimbic/infralimbic regions; ibotenic acid) using a va

176 was associated with greater hippocampal and prelimbic inputs.

177 Prelimbic knockdown of GR in females caused deficits in

178 dendritic arborization and spine density of prelimbic layer III neurons in prenatally stressed and c

179 onto inhibitory interneurons located in the prelimbic medial PFC, by virtue of reduced endocannabino

180 In adults, the prelimbic medial prefrontal cortex (mPFC) appears to be

181 Persistent IG occurs in rat prelimbic medial prefrontal cortex (mPFC), a crucial sit

182 The prelimbic medial prefrontal cortex (PL-mPFC) and basolat

183 of abuse cause dendritic spine plasticity in prelimbic medial prefrontal cortex (PL-mPFC) pyramidal n

184 Methylphenidate administration into the prelimbic, medial/ventral orbitofrontal, and ventrolater

185 ic synapses within both infralimbic (IL) and prelimbic mPFC (PrL) to NAc projections, measured after

186 d local field potentials (LFP) directly from prelimbic mPFC and examined the influence of tone-shock

187 venile rats infused with picrotoxin into the prelimbic mPFC and exposed to a threatening stimulus fro

188 ed and allowed a small meal, c-Fos counts in prelimbic mPFC and NAcc core were positively correlated,

189 In juveniles, the prelimbic mPFC became responsive in processing aversive

190 function localized to the anterior cingulate/prelimbic mPFC or dorsal CA3 hippocampus differentially

191 induced plasticity is impaired by removal of prelimbic mPFC PNNs and that PNNs may be a therapeutic t

192 Pre rats showed increased Egr-1 mRNA in the prelimbic mPFC relative to Alt-Pre rats.

193 lly, during adolescence, inactivation of the prelimbic mPFC significantly attenuated freezing and dec

194 levated numbers of Fos-positive cells in the prelimbic mPFC, the medial amygdala, and ventral PAG.

195 mitochondrial biogenesis and dynamics in the prelimbic mPFC.

196 smission in layer V pyramidal neurons in the prelimbic mPFC.

197 site was true of animals 36 h deprived, with prelimbic mPFC/NAcc core and infralimbic mPFC/NAcc shell

198 between mean c-Fos counts were found, though prelimbic mPFC/NAcc core and mPFC/NAcc shell were positi

199 short hairpin RNA targeting the GR into the prelimbic (n = 44) or infralimbic (n = 52) cortices.

200 l ensemble firing patterns revealed that the prelimbic network activity exhibited an abrupt transitio

201 Thus, prelimbic neurons are capable of rapidly forming ensembl

202 A subset of prelimbic neurons exhibited sustained increases in activ

203 Prelimbic neurons showed learning-related increases in a

204 discrete lesions of the infralimbic but not prelimbic or cingulate cortex made before but not after

205 croinjected into the anterior cingulate, and prelimbic or infralimbic cortices before cocaine reinsta

206 red impulsive behavior when infused into the prelimbic or infralimbic cortices.

207 to show significant neural activation in the prelimbic or infralimbic mPFC during the heroin-seeking

208 ual immunolabeling of these receptors in the prelimbic PFC (prPFC) and BLA of adult male rats.

209 ilver labeling for SERT (SERT-ir) in the rat prelimbic PFC and to describe its ultrastructural spatia

210 FC) input and provides moderate input to the prelimbic PFC and ventral tegmental area (VTA), with no

211 Knockdown of GR in the neighboring prelimbic PFC increased hypothalamic-pituitary-adrenocor

212 populations of SERT profiles within the rat prelimbic PFC that may arise from different raphe nuclei

213 ween presumed NE and DA axons within the rat prelimbic PFC, we combined immunogold-silver localizatio

214 ed on increased neuronal activity within the prelimbic PFC, which is considered the rodent functional

215 bserved after apamin microinfusions into the prelimbic PFC.

216 neous structure, and the contribution of the prelimbic (PL) and infralimbic (IL) cortices to recognit

217 Local field potentials were recorded from prelimbic (PL) and infralimbic (IL) mPFC during retrieva

218 Prelimbic (PL) and infralimbic (IL) neuronal activity ch

219 ced adaptations in intrinsic excitability of prelimbic (PL) and infralimbic (IL) pyramidal neurons; a

220 The prelimbic (PL) and infralimbic (IL) regions of the media

221 is heterogeneity in the contributions of the prelimbic (PL) and infralimbic (IL) regions of the media

222 The prelimbic (PL) and infralimbic (IL) regions of the rat p

223 prefrontal cortex (mPFC), we found that the prelimbic (PL) and infralimbic (IL) subregions of the mP

224 ormed tetrode recordings simultaneously from prelimbic (PL) and rostral (rACC) and caudal (cACC) ante

225 The prelimbic (PL) area and basolateral amygdala (lateral [L

226 irect projections from dorsal hippocampus to prelimbic (PL) cortex and activation of critical PL mole

227 ampus (vHPC) inputs to fear signaling in the prelimbic (PL) cortex, a PFC region critical for the exp

228 The prelimbic (PL) cortex, a subregion of prefrontal cortex,

229 ly, the ventral tegmental area (VTA) and the prelimbic (PL) cortex.

230 med by projections from infralimbic (IL) and prelimbic (PL) cortices.

231 In rodents, the dorsal/prelimbic (PL) medial PFC (mPFC) is frequently considere

232 asolateral nucleus of the amygdala (BLA) and prelimbic (PL) medial prefrontal cortex have been implic

233 Plasticity in the prelimbic (PL) medial prefrontal cortex is critical to t

234 ntaining a working memory buffer, neurons in prelimbic (PL) mPFC may selectively contribute to learni

235 fear responses, and facilitates activity in prelimbic (PL) neurons involved in fear expression.

236 This avoidance requires prelimbic (PL) PFC, basolateral amygdala (BLA), and vent

237 input from the ventral hippocampus (VH) and prelimbic (PL) prefrontal cortex and may integrate VH an

238 Specifically, the rodent prelimbic (PL) prefrontal cortex drives fear expression

239 on and stimulation studies suggests that the prelimbic (PL) prefrontal cortex is necessary for expres

240 reduced the excitability of regular spiking prelimbic (PL) projection neurons, through a learning-re

241 By contrast, the neighboring prelimbic (PL) pyramidal neurons, which normally inhibit

242 The prelimbic (PL) region of prefrontal cortex has been impl

243 Here, we show that the dorsal, prelimbic (PL) region of the medial PFC aids active avoi

244 Inactivation of the prelimbic (PL) region of the medial prefrontal cortex by

245 Microinjection of ketamine into the prelimbic (PL) region of the medial prefrontal cortex du

246 yramidal neurons in the infralimbic (IL) and prelimbic (PL) regions of the mPFC in mice.

247 ll mPFC subregions, anterior cingulate (AC), prelimbic (PL), and infralimbic (IL) but enhanced CRF-in

248 cute stress, notably from medial prefrontal [prelimbic (PL)] and hippocampal [ventral subiculum (vSUB

249 The areas studied were the prelimbic (PL, area 32) and infralimbic (IL, area 25) co

250 dividual layers of infralimbic (IL; area 25) prelimbic (PL; area 32), and dorsal anterior cingulate (

251 region of the anterior cingulate cortex (the prelimbic [PL] area) and striatum.

252 or infusions of memantine directly into the prelimbic (PLmPFC) or infralimbic medial PFC (ILmPFC).

253 itioned locomotion and Fos activation in the prelimbic portion of prefrontal cortex and the nucleus a

254 SST-IRES-Cre mice were injected in FC (prelimbic/precingulate) with CRE-dependent adeno-associa

255 sociative memories, neuron firing in the rat prelimbic prefrontal cortex (mPFC) became less selective

256 demonstrated that the LHAad receives robust prelimbic prefrontal cortex (PFC) input and provides mod

257 nstatement are glutamatergic inputs from the prelimbic prefrontal cortex (PL) and dopamine from the v

258 The prelimbic prefrontal cortex (PL) has consistently been f

259 The prelimbic prefrontal cortex (PL) is a brain region integ

260 tinct layers and neuronal populations of the prelimbic prefrontal cortex (PL).

261 plasticity of glutamatergic synapses in the prelimbic prefrontal cortex (PL-PFC).

262 ow that the mouse basolateral amygdala (BLA)-prelimbic prefrontal cortex (plPFC) circuit is engaged b

263 ences learning-induced IEG expression in the prelimbic prefrontal cortex (PLPFC) through its interact

264 5-min pretreatment) acts directly within the prelimbic prefrontal cortex (PrL-PFC) to potentiate rein

265 pe-1 receptor (CB1R)-mediated actions in the prelimbic prefrontal cortex (PrL-PFC).

266 The rat prelimbic prefrontal cortex and nucleus accumbens core a

267 This included connectivity between the prelimbic prefrontal cortex and other areas of the front

268 reakdown of endocannabinoid signaling in the prelimbic prefrontal cortex is a core neurobiological su

269 The prelimbic prefrontal cortex is necessary for associating

270 h and decreased complexity of neurons in the prelimbic prefrontal cortex, a brain region important in

271 mmunoreactivity in axon terminals within the prelimbic prefrontal cortex, consistent with postulates

272 s, secondary motor cortex, gustatory cortex, prelimbic prefrontal cortex, orbital cortex, and the ant

273 amygdala, dorsal hippocampus, infralimbic or prelimbic prefrontal cortex.

274 structures, specifically the infralimbic and prelimbic prefrontal cortices, is required for compensat

275 show that in vivo optogenetic stimulation of prelimbic (PrL) and infralimbic (IL) cortical afferents

276 actor DeltaFosB in mPFC, specifically in the prelimbic (PrL) area, mediates susceptibility to stress.

277 The prelimbic (PrL) cortex constitutes one of the highest le

278 Dysregulation of the pathway from the prelimbic (PrL) cortex to the nucleus accumbens is impli

279 tex, but had no effect when infused into the prelimbic (PrL) cortex.

280 The hippocampus (HC) and prelimbic (PrL) subregion of the medial prefrontal corte

281 Oscillations were elicited in the prelimbic (PrL), infralimbic (IL) and the dorsopeduncula

282 C sub-regions have been proposed to promote (prelimbic, PRL) or inhibit (infralimbic, IL) these behav

283 esions were made in the mPFC centered on the prelimbic region (Brodmann's area 32) or the cingulate c

284 The prelimbic region (PL) of the medial prefrontal cortex (m

285 of the orbital prefrontal cortex (PFo), the prelimbic region of the medial prefrontal cortex (PL), a

286 p-regulation of immediate early genes in the prelimbic region of the medial prefrontal cortex, and th

287 ound that removal of PNNs primarily from the prelimbic region of the mPFC of adult, male, Sprague Daw

288 y recorded action potentials of cells in the prelimbic region of the mPFC, while male rats received a

289 upon principal neurons within layer V of the prelimbic region of the mPFC.

290 the outflow of the principal neurons of the prelimbic region to contribute to termination of the str

291 ase onto principal neurons in layer V of the prelimbic region, when examined 1 h later, which was pre

292 in 0.5 mul/side) in infralimbic (IL) versus prelimbic regions of rat mPFC, in appetitive trace and l

293 Here we find that the infralimbic and prelimbic regions of the ventral medial prefrontal corte

294 of areas 4 and 6) as well as prefrontal and prelimbic regions.

295 These sustained prelimbic responses may provide a bridging code that all

296 in layer 2/3 of pyramidal neurons within the prelimbic subarea of the prefrontal cortex (PFC) accompa

297 ments confirmed projections from the rostral prelimbic subfield to separate populations of avBST neur

298 onal ensemble in the infralimbic but not the prelimbic subregion induced excessive alcohol seeking.

299 Previous research suggests that the prelimbic subregion of the medial prefrontal cortex (mPF

300 0 microinfused into the infralimbic, but not prelimbic, subregion of the mPFC-reduced binge-like eati