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1 H-2 transcripts localized to the presumptive presomitic and lateral plate mesoderm and CYP26 mRNA to
2   Furthermore, ectopic expression of Gas1 in presomitic cells attenuates the response of these cells
3                                      Lateral presomitic cells remain deep in the myotome and they dif
4 ion of cells in the segmental plate, lateral presomitic cells.
5                                         When presomitic explants are confronted with cells secreting
6 s of gene expression that travel through the presomitic mesoderm (PSM) and arrest at the position of
7 nic axis by sequential segmentation from the presomitic mesoderm (PSM) and differentiate into the seg
8 led somites are periodically formed from the presomitic mesoderm (PSM) and give rise to the vertebral
9 n clock are synchronized across cells in the presomitic mesoderm (PSM) and result in tissue-level wav
10            During this process, cells in the presomitic mesoderm (PSM) are first patterned into segme
11 ming of SHH and BMP signals controls whether presomitic mesoderm (PSM) cells will adopt either a chon
12 (NM) stem cells generate neural and paraxial presomitic mesoderm (PSM) cells, which are the respectiv
13 ock, a molecular oscillator expressed within presomitic mesoderm (PSM) cells.
14                            We show here that presomitic mesoderm (psm) cultured in the presence of Sh
15      Lunatic fringe (Lfng) expression in the presomitic mesoderm (PSM) cycles in the posterior PSM, i
16 e continuously produced posteriorly from the presomitic mesoderm (PSM) during body formation.
17 st, a cell motility gradient drives paraxial presomitic mesoderm (PSM) expansion, resulting in compre
18 by an ENU-induced mutation that disrupts the presomitic mesoderm (PSM) expression of Notch pathway ge
19 togenesis, cells are recruited to the caudal presomitic mesoderm (PSM) from the primitive streak (and
20 hicken embryo to demonstrate that the caudal presomitic mesoderm (PSM) has a key role in axis elongat
21 use embryo, timely somite formation from the presomitic mesoderm (PSM) is controlled by the "segmenta
22 ion of the Mesp genes within segments of the presomitic mesoderm (PSM) of different vertebrate specie
23 ic flux impacts embryonic development, using presomitic mesoderm (PSM) patterning as the experimental
24 omitogenesis model by confining hPSC-derived presomitic mesoderm (PSM) tissues in microfabricated tre
25  lunatic fringe (lfng) expression within the presomitic mesoderm (PSM), a hes6a gradient in the PSM n
26  motile cells that eventually constitute the presomitic mesoderm (PSM), a tissue that plays an import
27 e/notochord and surface ectoderm in cultured presomitic mesoderm (PSM), and is accompanied by a marke
28 Xena) localizes to the cell periphery in the presomitic mesoderm (PSM), and is enriched at intersomit
29            This operates in each cell of the presomitic mesoderm (PSM), but the individual cells drif
30 d signaling oscillations in cells within the presomitic mesoderm (PSM), from which somites, the preve
31 ng this process, paired somites bud from the presomitic mesoderm (PSM), in a process regulated by a g
32 oth genes are transcribed in the unsegmented presomitic mesoderm (PSM), newly formed somites, adaxial
33 anics of this elongation, which requires the presomitic mesoderm (PSM), remain poorly understood.
34 f Snail 1 and Snail 2 in the mouse and chick presomitic mesoderm (PSM), respectively.
35 terior-to-anterior signaling gradient in the presomitic mesoderm (PSM), which controls cell maturatio
36  of somites are rhythmically produced by the presomitic mesoderm (PSM).
37 ythmic activity of signaling pathways in the presomitic mesoderm (PSM).
38 itiation of transcription in the unsegmented presomitic mesoderm (PSM).
39 n of epithelial somites from the mesenchymal presomitic mesoderm (PSM).
40 es arise from somites, which derive from the presomitic mesoderm (PSM).
41 rm by an iterative process from unsegmented, presomitic mesoderm (PSM).
42  the somites, are rhythmically produced from presomitic mesoderm (PSM).
43 d DeltaD in the zebrafish nervous system and presomitic mesoderm (PSM).
44 ior positioning of boundary formation in the presomitic mesoderm (PSM).
45 ion, known as the segmentation clock, in the presomitic mesoderm (PSM).
46 ols the timing of maturation of cells in the presomitic mesoderm (PSM).
47 velike along the anteroposterior axis of the presomitic mesoderm (PSM).
48 es cause them to detach from the unsegmented presomitic mesoderm [1-3].
49  we show that beta1-integrin in the anterior presomitic mesoderm activates canonical Wnt signalling i
50 o, transcripts for Mf3 are restricted to the presomitic mesoderm and anterior neurectoderm and mesode
51 onic axis by regulating cell motility in the presomitic mesoderm and by controlling specification of
52 2 to restrict the anterior boundaries of the presomitic mesoderm and caudal progenitor pool.
53 pressed in a dynamic pattern in paraxial and presomitic mesoderm and developing somites during mouse
54  her1 and Delta D expression in the anterior presomitic mesoderm and disrupts myogenic differentiatio
55 inal cord, which is maintained by underlying presomitic mesoderm and FGF signalling, and neuronal dif
56 ph and ephrin signaling in the patterning of presomitic mesoderm and formation of the somites.
57 fic manner in the presumptive somites of the presomitic mesoderm and is required for normal somitogen
58 transcription factors TBX6 and PAX3 underpin presomitic mesoderm and neural crest, respectively.
59 cs the inducing effects of notochord on both presomitic mesoderm and neural plate explants of amniote
60                          Co-cultures between presomitic mesoderm and neural tube also supported vascu
61 e dsx, terra is transiently expressed in the presomitic mesoderm and newly formed somites.
62  of the DSL gene family, is expressed in the presomitic mesoderm and posterior halves of somites.
63 of gene expression by microarray between the presomitic mesoderm and the 5 most recently formed somit
64 erior Hox genes and that of marker genes for presomitic mesoderm and the chordoneural hinge.
65 ral tube, and by myogenic progenitors in the presomitic mesoderm and the hypaxial somites.
66  Pax3 emerging as the gatekeeper between the presomitic mesoderm and the myogenic lineage.
67 are expressed at the transition zone between presomitic mesoderm and the segmented somites.
68  the presumptive somite from the rest of the presomitic mesoderm and the subsequent morphological cha
69 ri somites formed without convergence of the presomitic mesoderm and were composed of only two cells
70 n somite number and size, restriction of the presomitic mesoderm anterior border, somite chevron morp
71  border, decreased adhesion at the notochord-presomitic mesoderm border, and tension at boundaries wi
72 d production of spinal cord neurectoderm and presomitic mesoderm cells from neuromesodermal progenito
73              We provide direct evidence that presomitic mesoderm cells oscillate asynchronously in ze
74  is to keep the oscillations of neighbouring presomitic mesoderm cells synchronized.
75 nscriptional oscillations of cyclic genes in presomitic mesoderm cells.
76            Dynamic expression of FGF8 in the presomitic mesoderm constitutes the wavefront of determi
77                     By employing explants of presomitic mesoderm cultured with constant levels of Wnt
78 the mesodermal compartment, genes regulating presomitic mesoderm differentiation are downregulated in
79 ly or indirectly regulates genes involved in presomitic mesoderm differentiation, somite formation an
80 ecific dependency on Hippo signalling during presomitic mesoderm differentiation-and provide an initi
81 itive endoderm and higher Wnt signals induce presomitic mesoderm differentiation.
82 ic mesoderm exhibits RALDH-2-IR but thoracic presomitic mesoderm does not.
83  Adaxial cells become distinguishable in the presomitic mesoderm during late gastrulation by their ex
84 eriodic cleavage of somites from unsegmented presomitic mesoderm during vertebrate segmentation.
85                                     Cervical presomitic mesoderm exhibits RALDH-2-IR but thoracic pre
86 ollagen explant model was developed in which presomitic mesoderm explants formed a vascular plexus in
87 yoD activation by recombinant Shh protein in presomitic mesoderm explants is defective in Myf5 null e
88 and induce dermomyotome marker expression in presomitic mesoderm explants, supporting the hypothesis
89 enous Myf5 expression in 10T1/2 cells and in presomitic mesoderm explants.
90 ovirus to overexpress Gli1, Gli2 and Gli3 in presomitic mesoderm explants.
91 mites of Shh null embryos and in explants of presomitic mesoderm from wild-type and Myf5 null embryos
92              Mouse-avian chimeras with mouse presomitic mesoderm grafts had graft-derived endothelial
93 trikingly, X-Delta-2 is expressed within the presomitic mesoderm in a set of stripes that corresponds
94 nction in stimulating the differentiation of presomitic mesoderm into dermomyotome.
95 role in the translation of the patterning of presomitic mesoderm into somites.
96                            It is likely that presomitic mesoderm is a vertebrate innovation made poss
97 eling, we demonstrate that C&E of the medial presomitic mesoderm is achieved by cooperation of planar
98                Notch pathway activity in the presomitic mesoderm is fundamental for management of syn
99 derm and neural plate, but its expression in presomitic mesoderm is initially unchanged.
100 nos, expression of genes in undifferentiated presomitic mesoderm is initiated, but not maintained.
101                       Expression of terra in presomitic mesoderm is restricted to cells that lack exp
102 ing model of somitogenesis supposes that the presomitic mesoderm is segmented into somites by a clock
103 ence of notochord (noto mutants) or when the presomitic mesoderm is substantially reduced (tbx16 muta
104 a segmental prepattern is established in the presomitic mesoderm of all these mutants and hox gene ex
105            When ectopically expressed in the presomitic mesoderm of chick embryos in ovo, Wnt-1 diffe
106 ature Hes7 transcripts are stabilized in the presomitic mesoderm of mutant mice, suggesting that both
107 tures dramatic loss of expression within the presomitic mesoderm of Notch/Delta pathway components an
108 in the Notch pathway were not altered in the presomitic mesoderm of paraxis(-/-) embryos.
109 h required for transcription in the anterior presomitic mesoderm of paraxis, Mesp1, Mesp2, Hes5, and
110 of Dll1 transcripts is also increased in the presomitic mesoderm of PS1(-/-) embryos, while the level
111 ate Notch ligand, is markedly reduced in the presomitic mesoderm of PS1-/- embryos compared to contro
112  a similar cycling expression pattern in the presomitic mesoderm of somite stage mouse embryos.
113         Marker analysis revealed that in the presomitic mesoderm of the mutant embryos, sharply demar
114 ly traveling segmentation clock waves in the presomitic mesoderm of the organoids, recapitulating cri
115                                          The presomitic mesoderm of vertebrates undergoes a process o
116 es not alter the expression of AmphiHox-1 in presomitic mesoderm or of alkali myosin light chain (Amp
117  The asymmetrical expression of Nr2f2 in the presomitic mesoderm overlaps with the asymmetry of the r
118                            Paraxial tissues (presomitic mesoderm plus neural plate and notochord) wer
119 is is established at the anterior end of the presomitic mesoderm prior to overt somitogenesis in resp
120 oid was composed of a neural tube flanked by presomitic mesoderm sequentially segmented into somites.
121        A molecular segmentation clock in the presomitic mesoderm sets the pace of somite formation(4)
122                           Here, we find that presomitic mesoderm solidification is driven by an intri
123 nally, we find that forest embryos have more presomitic mesoderm than prairie embryos and that this c
124  to (i) maintain the Fgf8 'wavefront' in the presomitic mesoderm that underpins axial elongation, (ii
125 lated to continuously release cells into the presomitic mesoderm throughout somitogenesis is not unde
126              Microarray studies of the mouse presomitic mesoderm transcriptome reveal that the oscill
127        These genes are thought to act in the presomitic mesoderm when cells form prospective somites,
128                   Cadherins are expressed in presomitic mesoderm where they delineate cells.
129 s towards definitive endoderm, precardiac or presomitic mesoderm within the first 24 h of differentia
130 ensive zone of unsegmented mesenchyme (i.e., presomitic mesoderm) intervening between the tail bud an
131 d in a dynamic, segmental pattern within the presomitic mesoderm, and alterations in the function of
132 ') intrinsic to the cells in the unsegmented presomitic mesoderm, and is manifested in cyclic transcr
133 bx6 is expressed in the primitive streak and presomitic mesoderm, and is sharply down-regulated upon
134 of Gdf11 expression in the primitive streak, presomitic mesoderm, and tail bud.
135 tablishment of a segmental prepattern in the presomitic mesoderm, anteroposterior patterning of each
136 erative manner in the developing somites and presomitic mesoderm, as is the Eph receptor EphA4.
137 ricted to the rostral-most somitomere of the presomitic mesoderm, at the times corresponding to the e
138 s demonstrated that Cerr1-expressing somitic-presomitic mesoderm, but not older Cerr1-nonexpressing s
139 ght to an end through a process in which the presomitic mesoderm, having first increased in size, gra
140 ownstream targets of Notch activation in the presomitic mesoderm, including EphA4, were transcribed n
141 Expression of Thylacine is restricted to the presomitic mesoderm, localising to the anterior half of
142 and HRT3 exhibited dynamic expression in the presomitic mesoderm, mirroring the expression of other c
143  in a complex pattern that includes paraxial presomitic mesoderm, notochord, branchial arches and neu
144 four distinct modules: dynamic events in the presomitic mesoderm, segmental determination, somite ant
145 xamined cell survival and gene expression in presomitic mesoderm, somites and neural tube of developi
146 rtebral patterning, Btg2 is expressed in the presomitic mesoderm, tail bud, and somites during somito
147  find that, soon after segmentation from the presomitic mesoderm, the future myotome spreads across t
148 entation clock) operates in the cells of the presomitic mesoderm, the immature tissue from which the
149 fng, Hes1, Hes5 and Hey1 is disrupted in the presomitic mesoderm, we suggest that the somitic aberrat
150 show that Fgf8 and Fgf17 are required in the presomitic mesoderm, whereas Fgf18 is required in the so
151      Cells of the tail bud and the posterior presomitic mesoderm, which control posterior elongation(
152 w normal expression of Wnt inhibitors in the presomitic mesoderm, which in turn constrain the levels
153 s are less severe for gene expression in the presomitic mesoderm, yet severe segmentation phenotypes
154 ssion of genes such as lunatic fringe in the presomitic mesoderm.
155 n clock that intrinsically oscillates within presomitic mesoderm.
156 ding the primitive streak, the node, and the presomitic mesoderm.
157 be readouts of a "segmentation clock" in the presomitic mesoderm.
158 rated by internal cells or compaction of the presomitic mesoderm.
159 regionalisation when located in the anterior presomitic mesoderm.
160  recently formed somites and in the anterior presomitic mesoderm.
161 marker genes X-Delta-2 and X-ESR5 within the presomitic mesoderm.
162 sic helix-loop-helix (bHLH) gene, within the presomitic mesoderm.
163 slow muscle differentiation from uncommitted presomitic mesoderm.
164 rtebrae, are rhythmically generated from the presomitic mesoderm.
165 ains the pool of caudal progenitor cells and presomitic mesoderm.
166 ion of the transcriptome taking place in the presomitic mesoderm.
167 d activates Notch signalling in the anterior presomitic mesoderm.
168 expression of a number of clock genes in the presomitic mesoderm.
169 he period of cyclic gene oscillations in the presomitic mesoderm.
170 llate in mouse do not cycle across the chick presomitic mesoderm.
171 rarp expression was completely absent in the presomitic mesoderm.
172  stem cells into lateral plate, cardiac, and presomitic mesoderm.
173 nals now elicit RA synthesis in neighbouring presomitic mesoderm.
174 f Drosophila and somitogenesis in vertebrate presomitic mesoderm.
175  somites, are rhythmically produced from the presomitic mesoderm.
176 derm and the posterior neural plate, not the presomitic mesoderm.
177 myotome of developing somites but not in the presomitic mesoderm.
178 rget gene expression throughout the node and presomitic mesoderm.
179 al for establishing segmental pattern in the presomitic mesoderm.
180 o, and loss of cyclic gene expression in the presomitic mesoderm.
181 olecular segmentation clock operating in the presomitic mesoderm.
182 ion coordination among adjacent cells in the presomitic mesoderm.
183  sequentially in a rhythmic fashion from the presomitic mesoderm.
184 -1 is no longer expressed in the somites and presomitic mesoderm.
185 omites (0 and -1) at the anterior end of the presomitic mesoderm.
186 ressed in a segmental pattern in the rostral presomitic mesoderm.
187 the oscillations of neighboring cells in the presomitic mesoderm.
188 -8 is normally downregulated within lateral (presomitic) mesoderm following gastrulation.
189 onomous function in stimulating migration of presomitic mesodermal cells away from the PS and a secon
190 odissected embryonic tissue from somitic and presomitic mesodermal tissue, we identified new genes en
191 evelopment, Tbx6 expression is restricted to presomitic, paraxial mesoderm and to the tail bud, which
192  lateral halves of newly formed somites, and presomitic (segmental plate) mesenchyme -- to participat
193 re used to identify MyoD expressing cells in presomitic tissues in vivo.
194 rface between the inductive axial and target presomitic tissues.

 
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