ライフサイエンスコーパス: primary brain tumor

1 NT Glioblastoma (GB) is the most devastating primary brain tumor.

2 rimary CNS lymphoma (PCNSL) is an aggressive primary brain tumor.

3 lastoma (GBM) is the most aggressive form of primary brain tumor.

4 the most prevalent and aggressive malignant primary brain tumor.

5 toma multiforme (GBM) is the most aggressive primary brain tumor.

6 cers including glioblastoma, the most lethal primary brain tumor.

7 orme (GBM) is the most common and aggressive primary brain tumor.

8 toma (GBM) is the most common and aggressive primary brain tumor.

9 mon, aggressive and highly malignant type of primary brain tumor.

10 strocytic tumors are the most common form of primary brain tumor.

11 (GBM), the highest grade and most aggressive primary brain tumor.

12 urvival in glioblastoma, a highly aggressive primary brain tumor.

13 ma multiforme is the most aggressive type of primary brain tumor.

14 Malignant glioma (MG) is the most lethal primary brain tumor.

15 Astrocytic tumor is the most prevalent primary brain tumor.

16 Glioblastoma multiforme (GBM) is a deadly primary brain tumor.

17 ovide insight into disease causation of this primary brain tumor.

18 e the motility-promoting role of brevican in primary brain tumors.

19 nitoring and targeting this pathway in these primary brain tumors.

20 terface, were estimated for 33 patients with primary brain tumors.

21 Astrocytomas are the most common primary brain tumors.

22 , Parkinson's disease, stroke, epilepsy, and primary brain tumors.

23 gent with a cytotoxic agent in patients with primary brain tumors.

24 entify new potential therapeutic targets for primary brain tumors.

25 genesis of oligodendrogliomas, a subtype of primary brain tumors.

26 ation, as well as in patients with untreated primary brain tumors.

27 g development, in response to injury, and in primary brain tumors.

28 gene transfer throughout highly disseminated primary brain tumors.

29 Glioblastoma (GBM) is the most lethal of primary brain tumors.

30 past, present, and future in the context of primary brain tumors.

31 studied for the treatment of peripheral and primary brain tumors.

32 ic disparities in the surgical management of primary brain tumors.

33 erapeutic opportunities to effectively treat primary brain tumors.

34 m occurs in up to one-third of patients with primary brain tumors.

35 vel insights into the pathogenesis of VTE in primary brain tumors.

36 Meningiomas account for one-third of all primary brain tumors.

37 that accounts for the majority of malignant primary brain tumors.

38 astoma multiforme (GBM), the most aggressive primary brain tumors.

39 ers to aid diagnosis and characterization of primary brain tumors.

40 understood comorbidity for individuals with primary brain tumors.

41 Among primary brain tumors, 15 of 17 glioblastomas, 3 of 4 mix

42 married, non-Hispanic white sample, 66% had primary brain tumors, 27% had brain metastases, and 8% u

43 Meningiomas are the most common primary brain tumors; a large percentage exhibit heteroz

44 lt glioblastoma (GBM) is a highly aggressive primary brain tumor, accounting for nearly half of all m

45 Glioblastomas (GBM) are the most prevalent primary brain tumors, affecting 5 in every 100,000 peopl

46 Malignant gliomas (primary brain tumors) aggressively invade the surroundin

47 oblastomas are the most prevalent and lethal primary brain tumor and are comprised of hierarchies wit

48 Gliomas are the most common malignant primary brain tumor and are often associated with severe

49 ma (GBM) is the most prevalent and malignant primary brain tumor and contains self-renewing, tumorige

50 Glioblastoma is the most common adult primary brain tumor and has a dismal median survival.

51 Glioblastoma (GBM) is the most common primary brain tumor and has a dismal prognosis.

52 Glioma is the most common malignant primary brain tumor and is associated with poor prognosi

53 ma multiforme (GBM) is the most common adult primary brain tumor and is comprised of a heterogeneous

54 Glioblastoma is the most aggressive primary brain tumor and responds poorly to currently ava

55 Meningiomas are the most common primary brain tumor and their incidence and prevalence i

56 e, 42 [33-54] years; 154 females [55%]) with primary brain tumors and 887 transplants from them, 778

57 mas (GBMs) are the most common and malignant primary brain tumors and are aggressively treated with s

58 nt gliomas are the most frequently occurring primary brain tumors and are resistant to conventional t

59 in the field of neurology, particularly for primary brain tumors and autoimmune neurological disorde

60 opyl)-l-glutamate ((18)F-FSPG) helped detect primary brain tumors and brain metastases with a high tu

61 tumors and whole-brain irradiation, 19 with primary brain tumors and chemotherapy only, 52 with prim

62 m of brain cancer, is responsible for 23% of primary brain tumors and has extremely poor outcome.

63 lpha(v)beta(3) is frequently up-regulated in primary brain tumors and metastatic lesions of brain hom

64 ictive of outcome in children with recurrent primary brain tumors and should be evaluated as a progno

65 hanced JNK activation is frequently found in primary brain tumors and that this activation contribute

66 patients operated for conditions other than primary brain tumors and was not age-dependent.

67 ed MR imaging examinations (55 patients with primary brain tumors and whole-brain irradiation, 19 wit

68 cts grouped for urgent referral, 2 confirmed primary brain tumors (and a possible but unconfirmed thi

69 tiforme (GBM) is the most aggressive type of primary brain tumor, and the presence of glioma stem cel

70 lid tumors, 50% (six of 12) of patients with primary brain tumors, and 0% (zero of nine) of patients

71 generative and neuroimmunological disorders, primary brain tumors, and psychiatric diseases.

72 Gliomas are the deadliest of all primary brain tumors, and they constitute a serious glob

73 Primary brain tumors are a major cause of cancer mortali

74 Due to lack of effective therapy, primary brain tumors are the focus of intense investigat

75 Malignant gliomas, the most common type of primary brain tumor, are a spectrum of tumors of varying

76 malignant glioma, the most lethal and common primary brain tumor, are undergoing a dramatic evolution

77 died prior to experiment termination, with a primary brain tumor as the cause of death.

78 In glioblastoma (GBM), an aggressive primary brain tumor, astrocytes become activated and tum

79 ally, examination of frozen sections from 10 primary brain tumor biopsies by immunohistochemistry rev

80 neural signaling mechanisms recapitulated in primary brain tumors, brain metastases, and solid tumors

81 acizumab is FDA-approved in the treatment of primary brain tumors, but its efficacy in patients with

82 -regulate or maintain EGFR overexpression in primary brain tumors by directly interacting with the re

83 nhanced our understanding of the genetics of primary brain tumors by uncovering several novel driver

84 In malignant primary brain tumors, cancer cells infiltrate into the p

85 Glioblastoma, the most common malignant primary brain tumor, carries an invariably poor prognosi

86 Malignant primary brain tumors cause more than 15 000 deaths per y

87 r, the subunit structure of this receptor in primary brain tumor cells is not known.

88 proliferation and invasive cell migration of primary brain tumors cells.

89 rme (GBM) are aggressive and uniformly fatal primary brain tumors characterized by their diffuse inva

90 Glioblastomas are the most aggressive primary brain tumors, characterized by their rapid proli

91 Glioblastoma (GBM), a lethal primary brain tumor, contains glioma stem cells (GSCs) t

92 Glioblastoma is a Grade 4 primary brain tumor defined by therapy resistance, diffu

93 transformed mouse embryo fibroblasts and for primary brain tumor development in a rat model of neuroc

94 clude 298 children under age 20 years with a primary brain tumor diagnosed from 1984 to 1991 and 298

95 Meningiomas, the most common primary brain tumor, exhibit Hedgehog signaling activati

96 These studies demonstrate that melanomas and primary brain tumors express common MAAs and could be ex

97 Gliomas are terrifying primary brain tumors for which patient outlook remains b

98 ic gliomas, the most common and malignant of primary brain tumors, frequently contain activating muta

99 The aggressive primary brain tumor glioblastoma (GBM) is characterized

100 The most common malignant primary brain tumor, glioblastoma multiforme (GBM) is a

101 f cancer, including the most common class of primary brain tumor, glioma.

102 Because the vast majority of primary brain tumors (gliomas) are derived from astrocyt

103 Primary brain tumors (gliomas) have the unusual ability

104 esions with good versus poor outcomes in the primary brain tumor group (P < .05) but not in the brain

105 Glioblastoma multiforme (GBM) is a fatal primary brain tumor harboring myriad genetic and epigene

106 Glioblastoma, the most lethal primary brain tumor, harbors glioma stem cells (GSCs) th

107 Glioblastoma (GBM), the most common adult primary brain tumor, has an average survival of only 15-

108 ics to glioblastoma (GBM), a very aggressive primary brain tumor, has not been fully explored.

109 Glioblastomas are the most common primary brain tumors, highly vascularized, infiltrating,

110 Glioblastoma is the most aggressive primary brain tumor in adults and due to the invasive na

111 Glioblastoma (GBM) is the most lethal primary brain tumor in adults and harbors a subpopulatio

112 blastoma (GBM) is the most common and lethal primary brain tumor in adults and is driven by self-rene

113 Glioblastoma is the most common form of primary brain tumor in adults and is essentially incurab

114 Glioblastoma is the most common primary brain tumor in adults from which about 15,000 pa

115 type (WHO grade 4) (GBM), is the most common primary brain tumor in adults with a 21-month median ove

116 Glioblastomas (GBMs), the most common primary brain tumor in adults, are characterized by resi

117 e (GBM) is the most prevalent and aggressive primary brain tumor in adults, characterized by a poor p

118 toma (GBM) is the most aggressive and lethal primary brain tumor in adults, characterized by resistan

119 ients with glioma, the most common malignant primary brain tumor in adults, examination of cell-free

120 toma multiforme, the most aggressive form of primary brain tumor in adults, is nearly universally fat

121 ioblastoma is the most common and aggressive primary brain tumor in adults, with a poor prognosis bec

122 stoma (GBM) is the most aggressive malignant primary brain tumor in adults, with incidence peaking in

123 he most common and most aggressive malignant primary brain tumor in adults.

124 toma (GBM) is the most common and aggressive primary brain tumor in adults.

125 is the most common and highly lethal form of primary brain tumor in adults.

126 Glioblastoma (GBM) is the most lethal primary brain tumor in adults.

127 ioblastoma multiforme is the most aggressive primary brain tumor in adults.

128 Glioblastoma is the most common primary brain tumor in adults.

129 multiforme (GBM), the most common and lethal primary brain tumor in adults.

130 oblastoma (GBM) is the most common malignant primary brain tumor in adults.

131 ltiforme (GBM) is the most common and lethal primary brain tumor in adults.

132 Medulloblastoma is the most common solid primary brain tumor in children.

133 Glioblastoma (GBM) is a lethal form of primary brain tumor in human adults.

134 oblastoma (GBM) is the most common and fatal primary brain tumor in humans, and it is essential that

135 Glioblastoma, the most aggressive primary brain tumor in humans, exhibits a large degree o

136 is the most common and aggressive malignant primary brain tumor in humans.

137 A history of primary brain tumor in the organ donor, identified from

138 Gliomas are the most common type of primary brain tumors in adults and a significant cause o

139 Gliomas are the most common primary brain tumors in adults, and remain refractory to

140 Malignant gliomas are the most common primary brain tumors in adults, and the most malignant f

141 ress has been made in this regard for common primary brain tumors in adults, especially diffuse gliom

142 Malignant gliomas are the most common primary brain tumors in adults, have no known etiology,

143 of glioblastomas, the most malignant of all primary brain tumors in adults, is responsive to TOP2 po

144 most common and aggressive form of malignant primary brain tumors in adults.

145 me (GBM) is the most frequent and aggressive primary brain tumors in adults.

146 e, constitute the most common and aggressive primary brain tumors in adults.

147 omas are the most common and the most lethal primary brain tumors in adults.

148 ancer survivors at risk of developing second primary brain tumors, in particular survivors of childho

149 Primary brain tumor incidence and survival patterns are

150 NRP/B expression was also observed in human primary brain tumors including glioblastoma multiformae

151 n institutional phase II trial for localized primary brain tumors, including craniopharyngioma, epend

152 er factor (HGF/SF) and Met staining in human primary brain tumors increases with the grade of maligna

153 In conclusion, high podoplanin expression in primary brain tumors induces platelet aggregation, corre

154 of cognitive deficits in adult patients with primary brain tumors is the tumor itself and more signif

155 a, the most aggressive and prevalent form of primary brain tumor, is characterized by rapid growth, d

156 Malignant glioma, the most common primary brain tumor, is generally incurable.

157 Glioblastoma, the most malignant type of primary brain tumor, is one of the solid cancers where c

158 Glioblastoma multiforme is a primary brain tumor known for its rapid proliferation, d

159 especially in indications such as gliomas, a primary brain tumor known for resistance to any immune i

160 Glioblastomas are aggressive primary brain tumors known for their inter- and intratum

161 analysis of 300 meningiomas, the most common primary brain tumors, leading to the discovery of mutati

162 Primary brain tumors mimic many aspects of NSC behavior.

163 Primary brain tumors, most commonly gliomas, are histopa

164 All 24 patients had a primary brain tumor, mostly low-grade glioma.

165 s: healthy brain (nonhuman primates (NHPs)), primary brain tumors (mouse glioblastoma), and metastati

166 ents (GBCAs) form the cornerstone of current primary brain tumor MRI protocols at all stages of the p

167 he nucleus of normal brain cells, whereas in primary brain tumors NRP/B was almost exclusively contai

168 lude the most common and the most aggressive primary brain tumor of adults and children.

169 ts use as a diagnostic marker to distinguish primary brain tumors of similar histology but different

170 Craniopharyngiomas, primary brain tumors of the pituitary-hypothalamic axis,

171 Primary brain tumor or brain metastasis (HR 2.5; P = .00

172 oma were often misdiagnosed in the donors as primary brain tumors or cerebral hemorrhage.

173 inoma-associated fibroblasts, in contrast to primary brain tumors or normal brain tissue.

174 Primary brain tumors, particularly glioblastomas, remain

175 persomnolence, is a core symptom reported by primary brain tumor patients and often manifests after r

176 However, the relative rarity of primary brain tumors (PBTs) has limited their representa

177 been used in the evaluation of patients with primary brain tumors (PBTs), but so far series have repo

178 Primary brain tumors present significant challenges for

179 pramolecular hydrogel effectively suppresses primary brain tumor recurrence and prolongs overall surv

180 was performed on 27 children with recurrent primary brain tumors referred to our institution for inv

181 Therapy for gliomas, the most common type of primary brain tumors, remains suboptimal.

182 multiforme (GBM), the most common malignant primary brain tumor, represents a significant disease bu

183 n 10 of 11 brain tumor cell lines and 3 of 5 primary brain tumor samples.

184 analysis demonstrated that 86% (18 of 21) of primary brain tumors showed evidence of JNK activation b

185 Single-cell sequencing of primary brain tumors shows PTPRZ1 overexpression in mali

186 Primary brain tumors, such as glioblastoma (GBM), are re

187 Primary brain tumors, such as glioblastoma multiforme or

188 Glioblastoma multiforme is a primary brain tumor that is highly resistant to irradiat

189 Gliomas are primary brain tumors that arise from differentiated glia

190 In the case of primary brain tumors that commonly affect adults, an eme

191 This article reviews the classification of primary brain tumors, the histologic changes associated

192 In participants with primary brain tumors, the predictive accuracy of the rel

193 ials using novel agents for the treatment of primary brain tumors, there have been few advances that

194 has been shown to be frequently activated in primary brain tumors, to enhance several tumorigenic phe

195 els in individual cells in sections from 167 primary brain tumors treated with BCNU were quantitated

196 Glioblastoma, the most common and aggressive primary brain tumor type, is considered an immunological

197 e glycoprotein, increases the risk of VTE in primary brain tumors via its ability to induce platelet

198 odds ratio for a validated family history of primary brain tumor was 2.3 (95% CI 1.0-5.8).

199 he expression of NRP/B mutants isolated from primary brain tumors was found in the cytoplasm, and the

200 ion in transplants from deceased donors with primary brain tumors was lower than previously thought,

201 ion of these gene-inactivation mechanisms in primary brain tumors, we integrated RLGS-based methylati

202 Twelve patients with primary brain tumors were imaged for 90 min of dynamic 1

203 ents with refractory solid tumors, excluding primary brain tumors, were eligible.

204 e (MR) images in a cohort of patients with a primary brain tumor who had not received linear gadolini

205 posure for pediatric and adult patients with primary brain tumors will be reviewed.

206 Glioblastoma (GBM) is the most common primary brain tumor with a median survival under two yea

207 Glioblastoma (GBM) is an aggressive primary brain tumor with a poor prognosis and few effect

208 Glioma is the most common malignant primary brain tumor with aggressiveness and poor prognos

209 Meningioma is the most prevalent primary brain tumor with extensive intra-tumoral heterog

210 Glioblastoma is a highly aggressive primary brain tumor with glioblastoma stem cells (GSCs)

211 Glioblastoma (GBM) is the most lethal primary brain tumor with intra-tumoral hierarchy of glio

212 lioblastoma (GBM) is an aggressive malignant primary brain tumor with limited therapeutic options.

213 ltiforme (GBM) is the most common and lethal primary brain tumor with median survival of only 12 to 1

214 ifome is the most common and most aggressive primary brain tumor with no current curative therapy.

215 Glioblastoma is the most common malignant primary brain tumor with poor overall survival.

216 Glioblastoma (GBM) is a hypervascular primary brain tumor with poor prognosis.

217 to HSP90 inhibitors in glioblastoma (GB), a primary brain tumor with poor prognosis.

218 f dying as a result of the transmission of a primary brain tumor with the risks of dying if not trans

219 Gliomas are primary brain tumors with a complex biology characterize

220 Glioblastomas (GBMs) are the most aggressive primary brain tumors, with an average survival of less t

221 brain tumors and chemotherapy only, 52 with primary brain tumors without any treatment, and 18 with