ライフサイエンスコーパス: primary culture

1 n were decreased in PAH smooth muscle cells (primary culture).

2 f keratin filaments in skin keratinocytes in primary culture.

3 ventricular myocytes and those in short-term primary culture.

4 es in recombinant systems and rat neurons in primary culture.

5 whereas CN neurons were from postnatal mouse primary cultures.

6 r dendritic spine density in rat hippocampal primary cultures.

7 and differentiation of human fibroblasts in primary cultures.

8 RNA populations in terminally differentiated primary cultures.

9 ased dendritic arborization and soma size in primary cultures.

10 gulf red blood cells in the ICH brain and in primary cultures.

11 the androgen receptor in female genital skin primary cultures.

12 s for Arc overexpression were performed from primary cultures.

13 thalamic cell line mHypoE-N41 and ARC neuron primary cultures, 2) likewise blocked by a peroxisome pr

14 In choroid plexus primary cultures, Abeta administration reduced endogenou

15 JIP3 knockout mouse neuron primary cultures accumulate lysosomes within focal axona

16 from C57BL/6 transgenic mice were studied in primary cultures, allowing for visualization of soma and

17 e, NHE5 depletion in rat cortical neurons in primary culture also inhibits neurite formation.

18 th commercial AMSCs and BMSCs as compared to primary culture AMSCs, suggesting primary cultures have

19 ventricular cardiomyocytes were incubated in primary culture and exposed to isoproterenol (1 mumol/L)

20 tin induces senescent-like neuronal cells in primary culture and in mouse dorsal root ganglia (DRG),

21 nic and neuroprotective potential in ex vivo primary culture and in vivo zebrafish and mouse models.

22 WDR73 p.Phe296Leufs*26 proliferate poorly in primary culture and senesce early.

23 ochondrial architecture was observed both in primary cultures and brown adipose tissue from cold-expo

24 and potentiator combinations were tested in primary cultures and conditionally reprogrammed cells ge

25 arkers were investigated in 25 human CCAs in primary cultures and established cell lines.

26 Cytokine expression in mixed foetal primary cultures and hippocampus of adults with Down syn

27 Bmal1 expression promoted neuronal death in primary cultures and in mice treated with a chemical ind

28 microglial responses to myelin pathology in primary cultures and in the cuprizone mouse model of mul

29 stable cell lines, low-grade glioma-derived primary cultures and NSCs.

30 re, in hippocampal pyramidal neurons of both primary cultures and slices, we triggered a unique form

31 n human lung fibroblasts were examined using primary cultures and the MRC5 cell line in vitro.

32 non-O157 STEC (n = 8) isolates, although the primary cultures and toxin assays were frequently negati

33 by intracellular glycine observed in vitro, primary cultures, and in vivo microdialysis.

34 We expressed the mutation in cell lines and primary cultures, and we evaluated the putative morpholo

35 to late in their embryogenesis to establish primary cultures, as these eggs contain cells that are p

36 onse to acute MeHg exposure in rat brain and primary cultured astrocytes to improve understanding of

37 ound by the phosphorylated forms of CRYAB in primary cultured astrocytes, we show that there is clear

38 alent cation-sensitive permeation pathway in primary cultured astrocytes.

39 Specifically, in hippocampal primary cultures, blocking c-Fos expression or its activ

40 Finally, in a cortical neuron primary culture, both Nanobodies were able to inhibit en

41 owever, C3aR1 responses were only present in primary cultures but not in situ, suggesting that the ex

42 prove salivary gland cell differentiation in primary cultures by using a combination of L1 and a feed

43 Conservatively, a secondary culture from the primary culture can be expanded up to 20-fold within 4-5

44 e the axon maintenance function of NMNAT2 in primary cultures, can also correct developmental defects

45 ositol 4,5-bisphosphate (PIP2) levels in the primary cultured cardiomyocytes from adult rats.

46 tiple QTL types in a highly disease-relevant primary cultured cell type and provide novel insights in

47 nregulation of multiple WNT-related genes in primary culture cells from ampullary adenocarcinoma, but

48 Experiments were also done ex vivo and with primary cultured cells in vitro.

49 lling-activated chloride current via VRAC in primary-cultured cortical astrocytes.

50 We found that in primary cultures derived from human haematopoietic proge

51 RUNX1 upregulation was a hallmark of EMT in primary cultures derived from human PVR membranes (C-PVR

52 Primary cultures derived from retinoblastoma tumors can

53 High-throughput screening of primary cultures derived from those xenografts identifie

54 in multiple glioma patient specimens, glioma primary cultures derived from tumors taken at surgery an

55 ithelial cultures, termed "mini-intestines." Primary cultures developed from isolated intestinal cryp

56 R-126 upregulation increased angiogenesis of primary cultured endothelial cells from patients with de

57 ys a floating, solid-walled enclosure as the primary culture environment, providing greater potential

58 In primary cultures, epithelial-mesenchymal transition mark

59 In primary culture, Esl-1(-/-) osteoclast progenitors show

60 Primary cultured fibroblasts from the siblings showed no

61 Here, we found that EC cells in mouse primary cultures fired spontaneous bursts of action pote

62 HGFs were primary cultured from human gingiva specimens.

63 unction in rat septal cholinergic neurons in primary cultures from E18.5 embryos and in the adult bra

64 We established primary cultures from follicular epithelium in human hom

65 d with established cell lines were seen with primary cultures from fresh tumors.

66 Primary cultures from murine cancers derived from prosta

67 ytes, oligodendrocytes, and microglia) using primary cultures from postnatal d 1 rat cortex.

68 d in the conditioned media of mixed cortical primary cultures from second trimester foetuses with Dow

69 ested the effect of SU6656 on differentiated primary cultures from severe asthma.

70 ompared to primary culture AMSCs, suggesting primary cultures have a slower growth rate than commerci

71 Primary-culture hBECs from subjects with mild to severe

72 ation with P300 antibody, in HepG2 and human primary culture hepatocytes.

73 Gluconeogenesis is also increased in primary cultured hepatocytes derived from LAdrKO mice.

74 In primary, cultured hepatocytes and precision-cut liver sl

75 , we inhibited F1Fo ATP synthase function in primary cultured hippocampal neurons by using non-lethal

76 ssenger RNA (mRNA) and protein expression in primary cultured human hepatocytes, and stimulated MDR3

77 X2 is up-regulated in lungs, distal PAs, and primary cultured human PASMCs isolated from PAH and comp

78 Klotho protein (KL) is expressed in primary cultured human RPE, and regulates pigment synthe

79 programs of hypoxic ECs by using RNA-Seq of primary cultured human umbilical vein ECs exposed to pro

80 amage induction and repair in cell lines and primary cultures, including cells with impaired repair m

81 From 65 patients, 27 primary cultures, including several from patients with s

82 Primary cultures, initiated from testes, were treated wi

83 Among 61 primary culture isolates (25 study group and 36 control

84 tically reduces sequencing error, to analyze primary cultured isolates phenotypically resistant to ri

85 KT restored normal Na+/K+-ATPase activity in primary cultured lens cells and reduced lens pressure in

86 ies and glutathione levels were increased in primary cultured macular Muller cells which were more su

87 lated reporter-tagged Mbp mRNA granules from primary cultured mammalian oligodendrocytes to show that

88 ieux), a chromogenic medium, to conventional primary culture medium for evaluation of urine specimens

89 ion changes that occur during development of primary cultured megakaryocytes (MEG) and primary erythr

90 tions of HDAC3 to inflammasome activation in primary cultured microglia and experimental stroke model

91 absent in melanoma 2 (AIM2) inflammasome in primary cultured microglia.

92 1 receptors, both receptors are expressed in primary cultured microglia.

93 A rat ENS primary culture model confirmed this expression.

94 trigger the activation of ATM or ATR in our primary culture model.

95 strong inhibitory effect on adipogenesis in primary cultured mouse ADSVFCs and human ADSCs.

96 We performed global expression profiling of primary cultured mouse and human macrophages, sampling a

97 In primary cultured mouse hepatocytes and HepG2 cells, the

98 various essential autophagy-related genes in primary cultured mouse hepatocytes and in mouse liver.

99 Furthermore, primary cultured mouse motor neurons showed axonal degen

100 we examined PLN stability and degradation in primary cultured mouse neonatal cardiomyocytes (CMNCs) a

101 We found primary cultured Muller cells from macula and peripheral

102 AVP stimulated GLP-1 and PYY release from primary cultured murine and human colonic cells and was

103 uptake via AMPK in skeletal muscle cells and primary cultured myoblasts.

104 into axons is required for axon survival in primary culture neurites and axon extension in vivo.

105 While rodent primary culture neuron systems have been described, thes

106 live-cell imaging of axonal transport in SCG primary culture neurons, we find that Nmnat2 is bidirect

107 e with an essential axon maintenance role in primary culture neurons.

108 e and boosts its axon protective capacity in primary culture neurons.

109 d enhances aggregation of alpha-synuclein in primary cultured neurons and in dopaminergic neurons of

110 ated oxidative stress-mediated cell death in primary cultured neurons at nanomolar concentrations.

111 We show that increased E6AP expression in primary cultured neurons leads to a reduction in dendrit

112 ant channels in both neuroblastoma cells and primary cultured neurons revealed clear genotype-phenoty

113 Furthermore, in primary cultured neurons, a proportion of UCH-L1(M) does

114 o mammalian-cultured cells, yeast, bacteria, primary cultured neurons, Drosophila melanogaster larval

115 In primary cultured neurons, NES mutations increase nuclear

116 tide in multiple mammalian cell lines and in primary cultured neurons.

117 in the murine hippocampus and in hippocampal primary culture, neurons of the CA1 region and the denta

118 Primary culture of cells allowed us to analyze their rel

119 t cells of human colon epithelial tissue and primary culture of colonic epithelial cells.

120 PGD2 levels were determined in a medium of primary culture of ENS and neuro-glial coculture model t

121 PGD2 levels were significantly increased on primary culture of ENS treated with LPS.

122 S induced higher levels of neuritogenesis in primary culture of enteric neurons, compared with contro

123 as breathing tumors by xenografting and as a primary culture of epithelial cells.

124 ta1 inhibitor, on the morphologic changes of primary culture of hGE cells were examined in vitro.

125 Here, we have used 14 d in vitro primary culture of hippocampal neurons and ex vivo prepa

126 We utilized a primary culture of human podocytes and 2 mouse models, t

127 evaluated the effect of recombinant uPAR on primary culture of human podocytes.

128 he mouse lungs and airway cells, including a primary culture of mucus-covered human airway epithelium

129 Here we establish a sustainable primary culture of Oct3/4(+)/Nanog(+) lung CSCs fed with

130 t1 expression and glucose consumption in the primary culture of osteoblast lineage cells, and deletio

131 d in HeLa cells or endogenously expressed in primary culture of pancreatic beta-cells.

132 b was rescued by human INPP5B insertion, and primary culture of proximal tubule cells (mPTCs) derived

133 umour epithelial cells by almost two-fold in primary culture of tumour cells from Apc(Min/+) mice.

134 ascular cell adhesion molecule-1 (VCAM-1) in primary culture of tumour endothelial cells.

135 calcium current are significantly reduced in primary cultures of Ahnak knockout (KO) neurons compared

136 pH, viscosity, and antibacterial activity in primary cultures of airway epithelia from people with cy

137 We show here that in well-differentiated primary cultures of airway epithelial cells from human d

138 igate the expression levels of chemokines in primary cultures of ASM cells from asthmatics vs healthy

139 tases from eight craniotomy specimens and in primary cultures of astrocyte-enriched glial cells.

140 Infected mixed primary cultures of astrocytes and microglia had higher

141 increases the level of mRNA encoding xCT in primary cultures of astrocytes isolated from mouse corte

142 In vitro studies using primary cultures of bone marrow monocyte-derived macroph

143 In primary cultures of bone marrow, we showed that GW9508,

144 GDF15 was found upregulated in situ and in primary cultures of CAF from prostate cancer.

145 rleukin (IL)8 messenger RNA by AGS cells and primary cultures of canine parietal and mucus cells.

146 sayed in left ventricular cardiac tissue and primary cultures of cardiomyocytes from fetal (100- and

147 In primary cultures of cardiomyocytes, overexpression of mi

148 In vitro, primary cultures of CB1 receptor-deficient KC released i

149 In vitro analyses using primary cultures of CD47-deficient murine colonic IEC or

150 In response to IL-1beta, primary cultures of central nervous system ECs produce G

151 However, acute deletion of Sox2 from primary cultures of CGNPs with constitutive Shh signalin

152 Using serum-free primary cultures of chick lens epithelial cells (DCDMLs)

153 aling in colorectal cancer cell lines and in primary cultures of colorectal cancer metastases.

154 tion of heparan sulfate was also detected in primary cultures of cortical neural cells, especially as

155 n A under global hypoxia without ischemia in primary cultures of cortical neurons and in neonatal and

156 u changes in 22 women (aged 19-81 years) and primary cultures of dermal fibroblast and dermal sheath

157 vity, and we conducted in vitro studies with primary cultures of differentiated human adipocytes and

158 Its addition to primary cultures of differentiating oligodendrocyte prec

159 Similar cells were present in primary cultures of dissociated cells from E10.5 embryon

160 ctrophysiological activity was recorded from primary cultures of dissociated rat cortical neurons pla

161 photosensitivity and functioning of HCs from primary cultures of embryonic retinas at day 15 by using

162 In primary cultures of endothelial cells, vascular endothel

163 rheas, (R)-BPO-27 blocked fluid secretion in primary cultures of enteroids from human small intestine

164 Primary cultures of esophageal fibroblasts and muscle ce

165 n heterologous F508-CFTR-expressing cells or primary cultures of F508/F508 human bronchial epithelia.

166 The development of differentiated primary cultures of ferret nasal epithelial cells is an

167 For functional analyses, primary cultures of fibroblasts were obtained from 11 pa

168 Primary cultures of GCPs from Jdp2-KO mice at postnatal

169 In primary cultures of glial cells and in the in vivo mouse

170 We show in primary cultures of glioma stemlike cells that EGR1 cont

171 Primary cultures of hepatocytes derived from wild-type o

172 Primary cultures of HGFs were grown on Type I collagen m

173 In primary cultures of hippocampal neurons from knockouts,

174 Overexpression of miR-132 in primary cultures of hippocampal neurons or delivered dir

175 Primary cultures of hippocampal neurons were used to sel

176 observed in mammalian cell lines as well as primary cultures of hippocampal neurons.

177 alyzed the effects of conditioned media from primary cultures of human ADPKD cystic epithelial cells

178 In well-differentiated primary cultures of human airway epithelial cells from n

179 e wild-type MV spread in well-differentiated primary cultures of human airway epithelial cells.

180 2, inhibit its expression, and are active in primary cultures of human cutaneous cells.

181 (3) (-) transport, we studied differentiated primary cultures of human cystic fibrosis (CF) and non-C

182 d DeltaF508-CFTR-mediated Cl(-) transport in primary cultures of human cystic fibrosis airway epithel

183 In contrast, in primary cultures of human fetal kidney cells, which main

184 Primary cultures of human GFs and PDLFs were isolated.

185 Primary cultures of human gingival fibroblasts (HGFs) we

186 define the complex protein mixtures found in primary cultures of human intrahepatic biliary epithelia

187 In this report, we used primary cultures of human iris stroma (HIS) cells derive

188 nd stimulates repair-associated responses in primary cultures of human keratinocytes and fibroblasts,

189 In primary cultures of human monocytes or alveolar type 2 c

190 (PPP) on osteoblastic differentiation using primary cultures of human periodontal ligament stem cell

191 ion effectively reduced the proliferation of primary cultures of human pleural (Pl) MM, implicating n

192 riments, we suppressed miR-204 expression in primary cultures of human RPE using anti-miR-204.

193 Primary cultures of human saphenous vein endothelial cel

194 and endocrine regulation of sex steroids by primary cultures of human skin epidermal keratinocytes a

195 Primary cultures of human trabecular meshwork (TM) cell

196 of TGF-beta1 on VE-cadherin was confirmed in primary cultures of human trophoblast cells.

197 By contrast, primary cultures of invasive breast cancer cells convert

198 In primary cultures of isolated human ASM, we identified mR

199 renal ischemia-reperfusion injury model, and primary cultures of isolated tubular cells in a hypoxia-

200 4 (TLR4)-mediated signaling was assessed in primary cultures of Kupffer cells from ethanol- and pair

201 phological changes to the lipid membranes of primary cultures of living human trabecular meshwork cel

202 over, we could show that addition of BMP9 to primary cultures of LSECs prevented the loss of their fe

203 ut proliferating precursors were detected in primary cultures of lung tissue.

204 Influenza A virus (IAV) is a lytic virus in primary cultures of many cell types and in vivo.

205 origin of BDNF in platelets, we established primary cultures of megakaryocytes, the progenitors of p

206 Although primary cultures of mesothelial cells or submesothelial

207 Using primary cultures of microglia isolated from mouse brains

208 In primary cultures of mouse bone marrow-derived macrophage

209 to knock down individual DNMT expression in primary cultures of mouse embryonic cardiomyocytes.

210 of EcoHIV-induced inflammation in vitro, in primary cultures of mouse glial cells and in vivo, in a

211 agonists (rosiglitazone or pioglitazone) in primary cultures of mouse glial cells reversed EcoHIV-in

212 resses TNF-alpha and caspase-3 expression in primary cultures of mouse hepatocytes.

213 racterized the motility of Rab5 endosomes in primary cultures of mouse hippocampal pyramidal cells by

214 itionally, felodipine inhibition of LTCCs in primary cultures of mouse lens epithelial cells resulted

215 erstood, we addressed this issue with use of primary cultures of mouse mesencephalic dopaminergic neu

216 a phosphorylation-null Thr84 SV2A mutant in primary cultures of mouse neurons.

217 r RFS-associated kappaLCs (RFS-kappaLCs) and primary cultures of mouse PT cells exposed to low doses

218 cipates in interkeratin disulfide bonding in primary cultures of mouse skin keratinocytes.

219 In this paper, using primary cultures of mouse tracheal epithelial cells, we

220 experiments in C2C12 and MC3T3-E1 cells and primary cultures of murine bone marrow-derived mesenchym

221 ANKRD55 was produced by primary cultures of murine hippocampal neurons and micro

222 ptide bond, and when pre-mixed with IL-23 in primary cultures of murine splenocytes inhibits IL-23-me

223 es such as cell migration were not affected, primary cultures of N-WASP-deficient podocytes revealed

224 Human cell lines and rat primary cultures of neurons and astrocytes were treated

225 Similar observations were made in the primary cultures of neurons derived from the hippocampi

226 the expression of the MCU channel subunit in primary cultures of neurons expressing a genetically enc

227 ocks alpha-synuclein-induced cytotoxicity in primary cultures of nigral dopaminergic neurons, and rec

228 itivity to axonal stress are also evident in primary cultures of Nmnat2 compound heterozygote superio

229 ced inflammatory responses were evaluated in primary cultures of non-CF versus CF AMs.

230 We confirmed in primary cultures of normal human bronchial epithelial ce

231 t treatment, oxygen concentration, etc.), in primary cultures of normal human dermal fibroblasts expo

232 tributed to a direct action of galectin-8 on primary cultures of osteoblasts that secrete the osteocl

233 When primary cultures of Pam (0-Cre-cKO/cKO) atrial myocytes

234 tagonist mifepristone each acted directly on primary cultures of parietal epithelial cells, inhibitin

235 with baseline expression of alphavbeta3, but primary cultures of peritoneal macrophages (PMo) require

236 human nectin-4 at promoting MV infection in primary cultures of porcine airway epithelia.

237 Primary cultures of porcine RPE cells were differentiate

238 Analysis of Pi transport in primary cultures of proximal tubular cells or in freshly

239 Using primary cultures of pure motoneurons or astrocytes from

240 OCs, as well as immature mononuclear OCs, in primary cultures of RANKL-stimulated bone marrow cells.

241 A, miR-487b, was further investigated, using primary cultures of rat aortic and human umbilical cord

242 embranes in LBs and LBPs freshly secreted by primary cultures of rat ATII cells has been compared wit

243 udy, we have investigated this phenomenon in primary cultures of rat cortical neurons using overexpre

244 lon of five CD and five control subjects, in primary cultures of rat enteric neurons and in nuclear f

245 analyze microtubule plus-end orientations in primary cultures of rat hippocampal and cortical neurons

246 Using primary cultures of rat hippocampal neurons as a quantit

247 atically analyze microtubule organization in primary cultures of rat hippocampal neurons, dentate gra

248 SLC4A7 can affect glutamate neurotoxicity in primary cultures of rat hippocampal neurons.

249 2-R by the reversible antagonist PSB-0739 in primary cultures of rat inner medullary CD cells potenti

250 Primary cultures of rodent sensory neurons are widely us

251 In primary cultures of steroidogenic small luteal cells (SL

252 se have been limited by the lack of extended primary cultures of the epithelium.

253 cytotoxicity of bFGF-NP were evaluated with primary cultures of the left ventricular (LV) cardiomyoc

254 Analysis of primary cultures of TMJ articular chondrocytes from wild

255 ed the invasiveness of HTR-8/SVneo cells and primary cultures of trophoblast cells.

256 Proteins bound to polyadenylated RNAs in primary cultures of undifferentiated spermatogonia were

257 unctional study of variants at this locus in primary cultures of vascular smooth muscle and endotheli

258 was performed on medial tissue extracts and primary cultures of VSMCs of human thoracic aneurysms (n

259 s were infected with MeV and then applied to primary cultures of well-differentiated airway epithelia

260 sing a TMEM106B HeLa knock-out cell line and primary cultured oligodendrocytes, we determined that lo

261 ce, and Synpo functions were investigated in primary cultured podocytes.

262 e have developed an in vitro BBB model using primary cultured porcine brain endothelial cells (PBECs)

263 slices from PS conditional knockout mice and primary cultured postnatal hippocampal neurons, in which

264 found that 3 different types of human ECs in primary culture produce clotting factors necessary for F

265 itotoxic stimulus in rat cortical neurons in primary culture promotes cyclin B1 accumulation in the m

266 Primary-cultured PVPV-Akt1KO thyrocytes uniquely display

267 s a correlation of apoD's ability to protect primary cultured rat cardiomyocytes from hypoxia/reoxyge

268 Primary cultured rat hepatocytes were transfected with s

269 teric small arteries, and Ca2+ signalling in primary cultured rat hippocampal neurones.

270 tion of a heteromeric TRPV4-C1-P2 complex in primary cultured rat mesenteric artery endothelial cells

271 ines, and during in vitro differentiation of primary cultured rat oligodendrocytes.

272 dependently up-regulated TRPC6 expression in primary cultured rat PASMCs, and this was accompanied wi

273 eterogeneity, as is generally encountered in primary cultures, reduces measurement yield and limits t

274 These altered primary cultures responded to both apical and basolatera

275 erentiation to syncytiotrophoblast (SynT) in primary culture, revealed that members of miR-515 family

276 In primary cultured rodent and human macrophages, CB1R acti

277 novirus 12 - SV40 hybrid (BEAS-2B) cells and primary cultures], roflumilast enhanced fluticasone prop

278 Using primary cultured Schwann cells, we analyze the upstream

279 Similar experiments with primary cultures showed protection and survival of perip

280 (PMT) in the following steps: at the end of primary culture, six serial cell passages of the control

281 e, we attempted to replicate this finding in primary cultured spinal cord neurons, spinal cord slice,

282 Here we describe an in vitro primary culture system for Caenorhabditis elegans germli

283 ights the utility of these three-dimensional primary culture systems.

284 Both in tissue slices and primary cultures, the NOP-eGFP receptors appear througho

285 yonic fibroblasts during the transition from primary culture through senescence and immortalization.

286 debridement and in rabbit corneal epithelial primary cultures through scratch injury.

287 In primary cultures treated with cyclosporin A, renal tubul

288 Conventional methods to extend the life of primary cultures typically utilize viral oncogenes.

289 ons, or induction of cell differentiation in primary cultures upregulated the number of cells permiss

290 strand DNA breaks and decreases viability in primary cultured uroepithelial cells.

291 gnant human myometrial cell line PHM1-41 and primary cultured uterine myocytes responded to Toll-like

292 Using behavioral, electrophysiological, and primary culture, we now demonstrate that reduced dopamin

293 nd invasion by isolated trophoblast cells in primary culture were significantly reduced in the presen

294 Glioma cell lines and low passage primary cultures were analyzed.

295 Primary cultures were established, monolayers wounded, a

296 GBM cell lines and primary cultures were found to express CD97.

297 ived and BM-derived alpha-SMA+ myofibroblast primary cultures were generated from four New Zealand wh

298 Primary cultures were initiated in modified Leibovitz's

299 a specimens and in high-grade glioma-derived primary cultures, whereas remaining low in glioblastoma

300 lastoma specimens, including patient-derived primary cultures, xenografts, genetically engineered gli