ライフサイエンスコーパス: primary immune response

1 ntly from common naive precursors during the primary immune response.

2 ritical role as APCs in the induction of the primary immune response.

3 ine signal to antigen-activated B cells in a primary immune response.

4 s suggesting that B cells play a role in the primary immune response.

5 s bacteriophage in a process that mimics the primary immune response.

6 ic use (pLAIVs), but they failed to elicit a primary immune response.

7 ew that the spleen plays a minor role in the primary immune response.

8 duced retention in the bone marrow after the primary immune response.

9 l T cells that controls the magnitude of the primary immune response.

10 could predict the size and diversity of the primary immune response.

11 ng cells are replenished every 24 h during a primary immune response.

12 ons to control CD4(+) T cell fate during the primary immune response.

13 e DC apoptosis to counterbalance the nascent primary immune response.

14 ith T cells led to the induction of a potent primary immune response.

15 production that are not observed during the primary immune response.

16 ity increasing mutations by days 9-14 of the primary immune response.

17 olved to cope with the different kinetics of primary immune responses.

18 enting cells with a unique ability to induce primary immune responses.

19 ibuting to the generation and maintenance of primary immune responses.

20 cells is a prerequisite for the induction of primary immune responses.

21 tute a unique family of cells able to induce primary immune responses.

22 otent antigen-presenting cells that initiate primary immune responses.

23 horin 6D as a regulator of the late phase of primary immune responses.

24 tigen-presenting cells capable of initiating primary immune responses.

25 ystem and have the unique capacity to induce primary immune responses.

26 Eosinophils were not required for primary immune responses.

27 and plays a critical role in the outcome of primary immune responses.

28 regulation, tumour surveillance and specific primary immune responses.

29 bility to stimulate resting naive T cells in primary immune responses.

30 city to stimulate naive T cells and initiate primary immune responses.

31 g cells that play a major role in initiating primary immune responses.

32 f 4-1BB costimulation for the development of primary immune responses, 4-1BBL-deficient (4-1BBL-/-) m

33 Following a primary immune response, a portion of effector T cells g

34 ow that CD86 is very effective in inducing a primary immune response against Line 1.

35 rom skin to regional lymph nodes to initiate primary immune responses against Ag encountered in skin.

36 lls, are thought to be crucial in triggering primary immune responses against both the graft and the

37 hat IFN-gamma plays an important role during primary immune responses against Friend virus but is dis

38 T cells into the memory compartment during a primary immune response also drive a rapid differentiati

39 emulsion alone, accelerated induction of the primary immune response and broadened its durability aga

40 germinal centre (GC) kinetics of the primed primary immune response and on affinity maturation obser

41 Ag was the superior means of both inducing a primary immune response and priming the mice to respond

42 olving HIV-1-suppressive activity during the primary immune response and that this activity is compri

43 naive CD4+ T cell exposure to antigen in the primary immune response and the quality of the memory ce

44 ry T cells represent a small fraction of the primary immune response and, at early time points, their

45 ) T cells showed signs of aging during their primary immune responses and differentiated into tissue-

46 Studies showed that AM14 RF B cells can make primary immune responses and do not downregulate sIgM, i

47 G-protein-coupled receptors is necessary for primary immune responses and for homing of leukocytes to

48 tery tertiary lymphoid organs participate in primary immune responses and organize T- and B-cell auto

49 Nonetheless, primary immune responses and the GC reaction in these mi

50 t with IL-12, allowed to progress beyond the primary immune response, and challenged by i.p. injectio

51 hils contribute to larval killing during the primary immune response, and neutrophils are effector ce

52 function as natural adjuvants to stimulate a primary immune response, and they may represent the natu

53 sm that may operate during the initiation of primary immune responses, and may prove useful as a stra

54 The primary immune response appears first and is inhibited b

55 ntrast, the presence of CD4 cells during the primary immune response appears to play a significant ro

56 ing that otherwise redundant components of a primary immune response are important for durable protec

57 clones that have expanded massively during a primary immune response are more prone to die as a resul

58 -specific T and B cells participating in the primary immune response are rapidly eliminated, but some

59 Primary immune responses are thought to be induced by de

60 hat diverse effector cell types arise in the primary immune response as a result of heterogeneity in

61 does not control CD4+ T-cell entry into the primary immune response, as a diverse range in affinity

62 lec1b(fl/fl)PF4-Cre mice are able to sustain primary immune responses but show a defect in immune cel

63 resenting cells are unable to sensitize in a primary immune response, but actively induce antigenic t

64 d that IL-2 sometimes contributes to optimal primary immune responses, but it is not mandatory.

65 ot only exhibit the unique capacity to evoke primary immune responses, but may also acquire TLR-trigg

66 s are not only critical for the induction of primary immune responses, but may also be important for

67 s of inflammation to lymph nodes to initiate primary immune responses, but the molecular mechanisms b

68 Isolation was achieved during the primary immune response by surface staining and flow cyt

69 responses by an adoptive transfer assay and primary immune responses by in vivo treatment of influen

70 We examined the induction of primary immune responses by insoluble GLU polypeptide de

71 These studies suggest that induction of primary immune responses by rAd5 gut immunization and su

72 Secondary lymphoid organs (SLOs) promote primary immune responses by recruiting naive lymphocytes

73 During a primary immune response CD8(+) T cells experience divers

74 Despite their critical function as APCs for primary immune responses, dendritic cells (DC) and Lange

75 Due to their capacity to induce primary immune responses, dendritic cells (DC) are attra

76 a potential deleterious role for Axl during primary immune responses directed against A. fumigatus a

77 a potential deleterious role for CCR7 during primary immune responses directed against A. fumigatus.

78 These experiments show that primary immune responses disappear in the absence of a t

79 sory molecules in cytokine production during primary immune responses, Drosophila cell lines expressi

80 ucleatum and human antimicrobial peptides in primary immune responses elicited by oral epithelium.

81 Primary immune responses following vaccination are initi

82 These findings suggest that there may be a primary immune response generated within the allograft a

83 racellular kinase cascades rapidly activates primary immune response genes.

84 A robust primary immune response has been correlated with the pre

85 ae through an MBP-dependent mechanism in the primary immune response if other effector cells are abse

86 V transformation is associated with a marked primary immune response in cord blood samples predominat

87 nsion are already present at the peak of the primary immune response in mice.

88 erred 0 to 24 h postvaccination stimulated a primary immune response in naive recipients.

89 Lack of primary immune response in severe combined immunodeficie

90 ion of an anti-Gag and -Gag peptide cellular primary immune response in vitro.

91 Prematurity did not influence primary immune responses in the presence of maternal ant

92 ions are required for many Th2-cell mediated primary immune responses including the response that fol

93 that have an unequaled capacity to initiate primary immune responses, including tolerogenic response

94 fed transgenic HBsAg potato tubers showed a primary immune response (increases in HBsAg-specific ser

95 e observed during the expansion phase of the primary immune response, indicating early defects in Th

96 Immunoglobulin A (IgA) is the primary immune response induced in the intestine by rota

97 The primary immune response is referred to as PAMP-triggered

98 profoundly reduced naive B cell numbers and primary immune responses, it had a markedly smaller effe

99 results in a functional reprogramming of the primary immune response, marked by altered T cell homing

100 immunity in mice and that the quality of the primary immune response may be playing a hitherto unreco

101 nT) in T cells, and demonstrated that T cell primary immune responses mediated through interaction be

102 es of Ag-specific cells (5-12.5%) similar to primary immune responses observed in vivo in murine mode

103 CXCR4 and CCR5 isolates of HIV-1 during the primary immune response of human CD4+ T cells.

104 that a population of B cells that dominates primary immune responses of BALB/c mice to influenza vir

105 In blood donors, primary immune responses of low and/or high avidity were

106 econdary lymphoid tissue either as a site of primary immune response or as a cache for excess T cell

107 elopment, the impact of low-dose Rapa on the primary immune response, particularly as it relates to f

108 y T cells maintain their predominance as the primary immune response progresses, with no enhancement

109 play an important role in the development of primary immune responses protective against HSV-2.

110 f HIV-specific T cell clones involved in the primary immune response rapidly disappeared.

111 expression inhibits, but does not eliminate, primary immune responses, reducing survival and increasi

112 However, the role of IPCs/PDCs in initiating primary immune responses remains elusive.

113 surface signals directly into T cells during primary immune responses, resulting in intrinsic T cell

114 ted at LBD fragments several weeks after the primary immune response suggests intramolecular epitope

115 After a primary immune response, T cell memory occurs when a sub

116 During the primary immune response, the expansion and contraction o

117 During the primary immune response, the magnitude of the CD4 and CD

118 ses not only avoid elimination by the host's primary immune response, they also remain with the host

119 ntigen-specific T helper (TH) cells during a primary immune response to a protein antigen.

120 ic to unrelated viruses may alter the host's primary immune response to a second virus.

121 ion of alpha146-162 peptide in IFA after the primary immune response to AChR also significantly suppr

122 likelihood for a role of MCs in influencing primary immune response to allergens has grown.

123 al expansion of PS-specific B cells during a primary immune response to an intact bacterium, as well

124 inally, treatment with Chi220 suppressed the primary immune response to cytomegalovirus, resulting in

125 The primary immune response to Gag elicited by rVSV peaked 7

126 Qualitative differences in the primary immune response to HIV (i.e. mobilization of a r

127 nstrated that qualitative differences in the primary immune response to HIV, but not quantitative dif

128 Mice deficient in C3 or Cr2 had an impaired primary immune response to III-PS.

129 duced lower levels of CD8(+) CTLp during the primary immune response to LCMV than did wild-type contr

130 (NK) cells are an important component of the primary immune response to most virus infections.

131 unodominant epitopes are known to suppress a primary immune response to other antigenic determinants

132 Inasmuch as T15-Id+ Abs dominate the primary immune response to PC in normal mice, it was sur

133 quired for the adjuvant effect of C3d on the primary immune response to PPS14 but were necessary for

134 ormalities have no detectable effects on the primary immune response to protein antigens.

135 on immune effector cell function during the primary immune response to several acute infections.

136 In the first week of the primary immune response to the (4-hydroxy-3-nitrophenyl)

137 ulation of these cytokines suggests that the primary immune response to the live infective stage of t

138 r (GC) B cells and plasma cells (PCs) during primary immune responses to a T cell-dependent hapten-pr

139 Primary immune responses to adenoviral vectors and the a

140 ortant in the early cellular response during primary immune responses to allergens.

141 lergic inflammation correlated with enhanced primary immune responses to allergic sensitization and e

142 recent evidence for a MC role in modulating primary immune responses to pathogens, the likelihood fo

143 ng is associated with a reduced magnitude of primary immune responses to vaccination.

144 ion determined by histology, indicating that primary immune responses to VSA(CSA) may not be sufficie

145 The maximum primary immune response was elicited with <0.1 microg of

146 During the primary immune response, we show generation of CD8+ memo

147 T cell-dendritic cell (DC) encounters during primary immune responses, we found that CCL21 addition t

148 All primary immune responses were confirmed by immunoblottin

149 tity, even at relatively early stages of the primary immune response when somatic mutation and clonal

150 pups were not infected and generated normal primary immune responses when challenged as adults.

151 ctive vaccine adjuvants for eliciting strong primary immune responses with a viral protein in vivo, p

152 as concluded that there is redundancy in the primary immune response, with eosinophils killing the la

153 rtial activation of B lymphocytes during the primary immune response, with generation of splenic germ