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2 o LOW PRO (0.7 g . d(-1)) compared with HIGH PRO (1.5 g . d(-1)) augments the postprandial availabili
3 = 0.25). kg(-1) . d(-1)) compared with HIGH PRO (1.5 g . kg(-1) . d(-1)) augments the postprandial a
4 od was greater after LOW PRO than after HIGH PRO (61% +/- 1% compared with 56% +/- 2%, respectively;
6 cently, the tetrapetide N-acetyl-Ser-Asp-Lys-Pro (Ac-SDKP) has emerged as a potent antifibrotic agent
7 urrence of a cardiac event compared with Pro/Pro + Ala/Pro genotypes in multivariate analysis (odds r
9 nges between assessments in the clinical and PRO "anchor" variables were classified as improved, stab
10 embrane-bound TIMP-1 is the PMN receptor for pro- and active MMP-8 and -9 as shown by the following:
12 The inhibitory effects of amino acids on Pro- and Ala-stimulated R(N) were mitigated by inhibitio
13 (121), but binding kinetics of the other two pro- and all anti-angiogenic splice variants are not kno
14 entially modulate the expression of selected pro- and anti- inflammatory mediators such as IL-6 and I
17 ivity via B face, proposing a model that the pro- and anti-amyloidogenic activities of SAP are not mu
22 owever, SMAD1/5/8 signalling results in both pro- and anti-angiogenic outputs, highlighting a poor un
23 doglin modulates the crucial balance between pro- and anti-angiogenic signaling by activin receptor-l
24 al exon to produce two families of isoforms, pro- and anti-angiogenic, only the former of which is up
25 flow cytometry to analyze the expression of pro- and anti-apoptotic Bcl-2 family members in T cells
27 poptotic proteins, WM samples expressed both pro- and anti-apoptotic Bcl-2 proteins at low levels sim
28 , called mito-priming, uses co-expression of pro- and anti-apoptotic Bcl-2 proteins to engineer Bcl-2
37 Our method facilitates discovery of novel pro- and anti-fibrotic agents in 384-well plate format a
44 isms downstream of Trem2 in coordinating the pro- and anti-inflammatory balance of microglia, particu
46 mass spectrometry measurements of a panel of pro- and anti-inflammatory bioactive lipids, we measure
47 y mechanisms leading to an imbalance between pro- and anti-inflammatory components of the immune syst
49 wever, exposure of PMN to Mtb LAM did elicit pro- and anti-inflammatory cytokine production and relea
50 ammatory responses through the regulation of pro- and anti-inflammatory cytokine production, (ii) the
53 phology and function in hypertension, and on pro- and anti-inflammatory cytokines (PICs and AIC) and
54 rs in the untreated CLP group, comprising 14 pro- and anti-inflammatory cytokines and 8 chemokines, g
55 y increased serum concentrations of multiple pro- and anti-inflammatory cytokines and chemokines when
56 WT) Y. pestis results in significant loss of pro- and anti-inflammatory cytokines and chemokines, esp
57 STAT5 regulate the critical balance between pro- and anti-inflammatory cytokines and how common dise
58 ing threshold determines whether PRR-induced pro- and anti-inflammatory cytokines are reciprocally re
59 diatric acute respiratory distress syndrome, pro- and anti-inflammatory cytokines are strongly associ
60 d the circulating levels of a large panel of pro- and anti-inflammatory cytokines in asymptomatic, in
61 on activation; additionally, B cells produce pro- and anti-inflammatory cytokines in response to cert
63 is threshold; consequently, both PRR-induced pro- and anti-inflammatory cytokines were decreased.
64 we hypothesized that patients with elevated pro- and anti-inflammatory cytokines would have higher m
65 a comprehensive leukocytosis, elevated serum pro- and anti-inflammatory cytokines, and evidence of in
66 trations of pregnancy-associated hormones or pro- and anti-inflammatory cytokines, and it had minimal
71 od correlated not only with higher levels of pro- and anti-inflammatory cytokines/chemokines (CCL2, I
72 injury, expression of adhesion molecules and pro- and anti-inflammatory cytokines/chemokines, microgl
73 mitter known to trigger pathways involved in pro- and anti-inflammatory effects in a dose-dependent m
76 f much debate, presumably due to the complex pro- and anti-inflammatory effects of this cytokine.
78 The sympathetic nervous system also has both pro- and anti-inflammatory effects on immune tissues and
84 ceptor-specific and combinatorial control of pro- and anti-inflammatory eicosanoid biosynthesis, and
86 ogenic T cells, zymosan induced a mixture of pro- and anti-inflammatory factors and Tregs, both in vi
92 s mucosal barrier function and expression of pro- and anti-inflammatory genes by intestinal epithelia
93 trum of inflammatory proteins upregulated by pro- and anti-inflammatory IL-2C treatment and uncover a
95 difference in the macropinocytic ability of pro- and anti-inflammatory macrophages that correlates w
96 detailed analysis of the effect of NFAT5 in pro- and anti-inflammatory macrophages uncovered its abi
97 is maintained through an adequate balance of pro- and anti-inflammatory macrophages, we assessed the
99 We investigated region-specific changes in pro- and anti-inflammatory markers in the mesocorticolim
100 with reductions of the classically activated pro- and anti-inflammatory markers, yet less oxidative s
102 ll line: RAW264.7) were treated with various pro- and anti-inflammatory mediators (cytokines, LPS, un
103 but mechanistically distinct, regulation of pro- and anti-inflammatory mediators in TR APOE4/4 murin
104 ion of miR-155 in response to the respective pro- and anti-inflammatory mediators LPS and IL-10.
106 y potential of diet, based on a summation of pro- and anti-inflammatory nutrients, is associated with
107 homeostasis that can rapidly switch between pro- and anti-inflammatory or regulatory modes to respon
108 iene receptor BLT2 is a receptor involved in pro- and anti-inflammatory pathways and can be activated
109 cytes and found increased expression of both pro- and anti-inflammatory pathways in tumor infiltratin
110 xygenase (5-LO) metabolism can activate both pro- and anti-inflammatory pathways, but their role in w
116 IL6 is a pleiotropic cytokine with both pro- and anti-inflammatory properties, which acts direct
119 or H. pylori MV in the stimulation of innate pro- and anti-inflammatory responses and in the suppress
120 the human immune system requires controlled pro- and anti-inflammatory responses for host defence ag
122 al structures necessitates a fine balance of pro- and anti-inflammatory responses; well-timed, approp
123 e suggest that this balance between the dual pro- and anti-inflammatory roles of C5aR2 ultimately dic
125 stinct immune cell populations that can play pro- and anti-inflammatory roles, and thus the compositi
127 disintegrin and metalloprotease 17) controls pro- and anti-inflammatory signaling events by promoting
128 ceptor clustering; it also provides clues to pro- and anti-inflammatory signaling pathways branching
131 ted overlapping multilineage phenotypes with pro- and anti-inflammatory transcripts of T(H)1, T helpe
132 tions, as well as regulatory cytokines, both pro- and anti-inflammatory, that are not typically produ
134 ng elastic net, we make novel predictions of pro- and anti-longevity genes that are not currently in
136 n areas that are capable of carrying diverse pro- and anti-micturition signals, and whose activity mo
141 nal disruption of regulatory DNA to decouple pro- and anti-oncogenic functions of a dominant transcri
149 OPBP1(Dpb11) provides binding sites for both pro- and anti-resection factors at DSBs, providing insig
151 helps to rationalize conflicting reports of pro- and anti-tumor effects of antioxidant treatment.
155 transcription factor C/EBPdelta can exhibit pro- and anti-tumorigenic activities, but the mechanisms
157 he individual immune components that possess pro- and anti-tumorigenic functions in individual cancer
158 kinase C alpha (PKCalpha) can activate both pro- and anti-tumorigenic signaling depending upon cellu
165 le cell-based assay that responds to complex pro- and antiangiogenic soluble factors with an in vitro
167 The Bcl-2 protein family comprises both pro- and antiapoptotic members that control the permeabi
171 s and that disruption of the balance between pro- and antiatherogenic immune cell subsets may trigger
172 is review, we discuss the novel concept that pro- and antiatherogenic immune responses toward unknown
175 rothrombin complex concentrate contains both pro- and anticoagulant factors that offer an attractive
176 rs of hemostasis by expressing and releasing pro- and anticoagulant mediators into the circulation.
180 e-week mortality was associated with greater pro- and antiinflammatory alterations of the innate immu
181 imental properties appeared favorable in the pro- and antiinflammatory cytokine balance, 1,25-dihydro
187 culature is tightly regulated by a wealth of pro- and antioxidant systems that orchestrate region-spe
190 liver regeneration, and they define specific pro- and antiregenerative molecular targets whose regene
191 ripheral nervous system (PNS) and CNS is the pro- and antiregenerative responses of their glial cell
194 ide a formal likelihood function of actions (pro- and antisaccades) and reaction times based on previ
195 biology, focusing on relevant TLR-dependent pro- and antitumor pathways, and discuss clinical applic
199 microenvironment is complex, containing both pro- and antitumorigenic elements, and remains to be ful
202 SP), which has been postulated to carry both pro- and antitumorigenic properties depending on tissue
203 ic, and microscopic analyses reveal that the pro- and antiviral effects of CRABPs are mediated by mod
211 are identified, distinct differences between pro- and eukaryotic phosphosignalling systems become app
214 the two arm regions of the prodomain in the pro- and latent myostatin homodimers, suggesting a 1:1 (
215 dy binding induces conformational changes in pro- and latent myostatin that span the arm region, the
217 e novo protein synthesis, and the release of pro- and mature IL-1beta from infected primary monocytes
218 s and report that in Drosophila melanogaster pro- and mature neurotrophins are capable of inducing de
220 ot prevent pro-domain processing between the pro- and metalloprotease domain, but nevertheless, cause
226 by reappearance of the visual landmark or a pro-/anti-reach instruction), the parietofrontal network
228 e Ile-Gln-Ala (beta-CN f187-189) and Val-Glu-Pro (beta-CN f116-118) having ACE IC50 values of 32.9+/-
229 es and proteases, abrogated the formation of pro- but also anti-inflammatory eicosanoids, and restore
230 sue biopsies to measure the total (CD68(+)), pro- (CD14(+) = M1), and anti- (CD206(+) = M2) inflammat
232 bone marrow, all B cell progenitors-from pre-pro-/early pro-B cells to immature B cells-were dramatic
234 etectable in the effluent unless Gly-Pro-Arg-Pro (GPRP) was added to block fibrin polymerization.
235 ihydroxyphenylalanine, Arg > Val > Lys, Tyr, Pro > hydroxyproline > alpha-aminobutyric acid > Gln, Th
237 ng additional hydrogen-bonding capacity, the Pro-->2-Hyp conversion alters the active site and enhanc
238 orticosterone, and mRNA expression levels of pro- (IL-1beta, IL-6) and anti-inflammatory (IL-10) cyto
239 nd depression surveys and provided blood for pro- (IL-1beta, IL-6, IL-8, TNF-a, IFN-gamma) and anti-i
242 ay inflammation, yet increased production of pro- (LTE(4) , PGD(2) and 11-dehydro-TBX(2) ) was balanc
244 is study was to test the hypothesis that the pro- or anti-adipogenic activity of phytoestrogen chemic
245 er the question whether netrin-4 acts either pro- or anti-angiogenic, angiogenesis in the retina was
246 ite dysregulation, leading to the release of pro- or anti-apoptotic factors which mediate cell surviv
248 nalling pathways or of altered expression of pro- or anti-apoptotic proteins can thus be compared.
250 GM-MO) or M-CSF (M-MO), which do not release pro- or anti-inflammatory cytokines unless subjected to
252 erest based on its ability to possess either pro- or anti-inflammatory effects mediated through p35-p
253 tes to differentiate and to be primed toward pro- or anti-inflammatory Mvarphis upon culture with GM-
254 gm, in which MSCs can be polarized towards a pro- or anti-inflammatory phenotype depending on the Tol
258 t only in a subset of patients, represents a pro- or anti-inflammatory state, its association with pr
260 d that the effects of IFN were not uniformly pro- or anti-inflammatory, but highly gene-specific and
261 First, by classifying aging-related genes as pro- or anti-longevity, we define distinct pathways and
262 se data provide biological evidence that the pro- or anti-obesity effects of phytoestrogens are relat
263 outputs in distinct hormonal context, having pro- or anti-proliferative effects, depending on the est
264 employing lepb-linked sequences upstream of pro- or anti-regenerative factors controlled the efficac
265 a controversial debate whether MSCs exert a pro- or anti-tumor action, mathematical models such as t
269 ure supports the idea that Akt can be either pro- or antiangiogenic, possibly due to compensation by
270 ast, a high-dose of MAGL inhibitors produces pro- or antidepressant effects on acute stress- or chron
271 itivity of the peripheral immune system to a pro- or antidepressant state, bone marrow (BM) chimeras
272 rate due to the probability of a trial type (pro- or antisaccade) are best explained by faster or slo
276 Although some effectors and PTMs have clear pro- or antiviral functions, PTMs generally play regulat
277 FD sensors are potentially applicable to any pro- or eukaryotic high-affinity ligand transport proces
278 ets, and subsequently differentiated into M1 pro- or M2 anti-inflammatory macrophages on stimulation.
280 This rise was +0.9 +/- 2.3 mm Hg for Icare PRO (P = 0.01) and +0.7 +/- 1.8 mm Hg for Tono-Pen (P =
281 ading the neutrophil chemoattractant Pro-Gly-Pro (PGP) and rationalized that the failure of conventio
282 report that the matrikine acetylated Pro-Gly-Pro (PGP) stimulates vascular inflammation through activ
284 presses IL-7R/JAK/STAT signaling to restrict pro-/pre-B progenitor expansion and leukemia development
287 A conserved late domain motif, Pro-Thr-Ala-Pro (PTAP), located in the p6 region of Gag (p6(Gag)), p
288 e a switch from preferential cleavage of the pro-(R) to the pro-(S) carboxylate group in the CLG-IPL
289 dipeptides: Ala-Arg (AR), Arg-Ala (RA), Arg-Pro (RP), Arg-Glu (RE), and Glu-Arg (ER); and two non-ar
291 preferential cleavage of the pro-(R) to the pro-(S) carboxylate group in the CLG-IPL variant of AMDa
295 DR5 downregulation and an inverted ratio of pro- to antiapoptotic molecules, both of which were reve
296 an thirty fold increase in the ratio of BDNF pro- to mature-domains in the brains of individuals with
298 andomly assigned clusters (1:1) with MapInfo Pro (version 11.0) to either the control or intervention