ライフサイエンスコーパス: pro-oxidant

1 gain entrance into cells and function as a 'pro-oxidant'.

2 iferone (2) and scopoletin (3) were slightly pro-oxidant.

3 etabolically active ferrous form is a strong pro-oxidant.

4 agent that can function as both an anti- and pro-oxidant.

5 as well as treatment with CdCl(2), a potent pro-oxidant.

6 carried out with manganese (30 microM) as a pro-oxidant.

7 C lost its antioxidant properties and became pro-oxidant.

8 eased fibromodulin production in response to pro-oxidants.

9 NRF2 binding until it becomes inactivated by pro-oxidants.

10 en pro-oxidants and antioxidants in favor of pro-oxidants.

11 es in the levels of mitochondrial Ca(2+) and pro-oxidants.

12 endent modulation in activity in response to pro-oxidants.

13 ssing CYP2E1 against cytotoxicity induced by pro-oxidants.

14 ofiles in response to herbicide safeners and pro-oxidants.

15 ibiting their interaction with water-soluble pro-oxidants.

16 crease in periodontal inflammation and serum pro-oxidants.

17 nce of ascorbic acid or 6-hydroxydopamine as pro-oxidants.

18 H in the three assays and in the presence of pro-oxidants.

19 to the oxidative stress initiated by chronic pro-oxidant Abeta exposure.

20 by itself is a mild antimicrobial and has a pro-oxidant ability.

21 lyphenols (PFs) play a key role due to their pro-oxidant action modulated by metallic cations.

22 Thus, due to apparent pro-oxidant action of DEDTC, our data do not support its

23 effect on lipid peroxidation, inducing both pro-oxidant actions at low (5-20) micromolar concentrati

24 beta1 from the heart and the profibrotic and pro-oxidant actions of TGFbeta1 in the liver and emphasi

25 dings suggest that, despite 3-HK might exert pro-oxidant actions under certain conditions, these chan

26 sed for quantifying simultaneously anti- and pro-oxidant activities as function of concentration and

27 f trout and bovine hemoglobin (Hb) and their pro-oxidant activities in washed cod muscle mince (WCM)

28 we directly demonstrated that both anti- and pro-oxidant activities of etoposide are realized in cell

29 nvironmental particulate matter (PM) directs pro-oxidant activities that may alter DC function.

30 In conclusion, honey phenolics with pro-oxidant activities were necessary intermediates that

31 ) systems] as well as for the observation of pro-oxidant activities, with the measurements registerin

32 At low content, honey polyphenols exerted pro-oxidant activity damaging to DNA.

33 eltacta1, Deltagsh1 and Deltaoye2glr1, while pro-oxidant activity in Deltasod1 cells was seen.

34 been observed to exert both antioxidant and pro-oxidant activity in lipid foods, and factors that in

35 4h, EGCG (5-100 muM) was observed to exhibit pro-oxidant activity in low pH (pH 2-4) emulsions, as de

36 tudy suggests that pheomelanin's redox-based pro-oxidant activity may contribute to sustaining a chro

37 However, this pro-oxidant activity of alpha-tocopherol is prevented by

38 (EGCG), and matrix pH (2-7) on the net anti-/pro-oxidant activity of EGCG in flaxseed oil-in-water (o

39 MPO-dependent pro-oxidant activity of etoposide was directly demonstra

40 radical species formed show a potential for pro-oxidant activity of this compound.

41 an antioxidant, PDTC has been shown to exert pro-oxidant activity on proteins both in vitro and in vi

42 ated with necroinflammatory, fibrogenic, and pro-oxidant activity via the NADPH oxidase 4.

43 id peroxidation; however, kombucha exhibited pro-oxidant activity when evaluated in its natural form

44 cells, controls S1P1 expression through its pro-oxidant activity.

45 aHb) to maintain its structure and limit its pro-oxidant activity.

46 not converted to reactive intermediates with pro-oxidant activity.

47 ct had indeed antioxidant protection, and no pro-oxidant activity.

48 None of the tested metals showed a pro-oxidant activity.

49 ess and have decreased circulating levels of pro-oxidant advanced glycation end-products (AGEs).

50 ile overexpression enhances survival against pro-oxidant agents but not heat or reductive stress.

51 hat sustained exposure to the high levels of pro-oxidant AGEs in normal diets (Reg(AGE)) contributes

52 Serum iron, a potential pro-oxidant, also decreased by 45% with exercise from 15

53 osure of primary rat cortical neurons to the pro-oxidant amyloid beta peptide promotes nuclear accumu

54 otein O3] and SOD2) and higher expression of pro-oxidant and aging mitochondria proteins p66(Shc) and

55 anoceria; CNPs) have been found to have both pro-oxidant and anti-oxidant effects on different cell s

56 A series of pro-oxidant and antioxidant enzymes, such as the NADPH o

57 Angiotensin II (Ang II) is a pro-oxidant and fibrogenic cytokine.

58 However, any form of iron is a pro-oxidant and its addition will cause off-flavours and

59 ministration of Levodopa (l-DOPA) which is a pro-oxidant and may disrupt sulfhydryl homeostasis.

60 PKCbeta phosphorylation sites regulating the pro-oxidant and pro-apoptotic function of p66.

61 unction and be partially responsible for the pro-oxidant and pro-inflammatory effects of uric acid.

62 g HMGB1 were more activated, showed enhanced pro-oxidant and pro-inflammatory signatures, and reduced

63 an antioxidant for cells susceptible to the pro-oxidant and proapoptotic properties of vitamin C.

64 Taken together, our data demonstrate a novel pro-oxidant and proapoptotic role of Trx in anthracyclin

65 alveolar bone loss (ABL) and serum levels of pro-oxidants and antioxidant enzymes in rats with experi

66 ve stress is defined as an imbalance between pro-oxidants and antioxidants in favor of pro-oxidants.

67 ase (12/15LO) enzyme is the source of potent pro-oxidants and inflammatory lipid mediators.

68 ecies (ROS), were hypersensitive to iron and pro-oxidants, and accumulated oxidatively damaged lipids

69 le cells exhibit an increased sensitivity to pro-oxidants, and conversely, Stra13 overexpression prov

70 dence for a mechanistic link between Ca(2+), pro-oxidants, and inhibition of complex I utilizing mito

71 ity: use of antioxidant crowns, chelation of pro-oxidants, and varying plant content in hops.

72 hod revealed that several factors, including pro-oxidant-antioxidant balance (PAB), physical activity

73 indings represent a promising start toward a pro-oxidant approach for cancer therapy.

74 Pro-oxidants are considered as major constituents of veh

75 dized glutathione and steady-state levels of pro-oxidants as assayed using an oxidation-sensitive flu

76 pe fruit and bush pruning residues acting as pro-oxidants as measured by the hydroperoxides levels.

77 essary energy expense or the accumulation of pro-oxidant assembly modules.

78 Remarkably alpha-tocopherol acted as a pro-oxidant at 25 and 40 degrees C, in particular during

79 d dose-dependent duality-antioxidant at low, pro-oxidant at high-consistent with mitochondrial damage

80 e cod protein in the presence and absence of pro-oxidants at pH 8 and 36 degrees C to achieve 20% deg

81 contributing to the observed antioxidant and pro-oxidant behavior of the different tocopherols were i

82 ical levels, ascorbate (P-AscH(-)) acts as a pro-oxidant by generating H(2)O(2), depleting ATP in sen

83 gen peroxide and diamide, although these two pro-oxidants by themselves had opposing effects on JNK1

84 olox and PhC can exert either antioxidant or pro-oxidant capacities depending on their concentration,

85 ly those with quinoa flour, reduced the AAPH pro-oxidant capacity in co-culture cells.

86 HA-mac contained more iron, a pro-oxidant catalyst, but paradoxically had less oxidati

87 on TTB stability could be due to a possible pro-oxidant character.

88 lioblastoma (GBM) cells to ascorbate through pro-oxidant chemistry involving redox-active labile iron

89 een shown to have pro-oxidant potential, the pro-oxidant chemistry of dihydrolipoic acid has not been

90 is emerging as promising cancer therapy via pro-oxidant chemistry.

91 useful tool to follow the combined effect of pro-oxidant chlorophylls and the protective light filter

92 Pro-oxidant components of PM2.5 are capable of directly

93 ondrial toxin 3-nitropropionic acid, and the pro-oxidant compound iron sulfate.

94 without exogenous supplementation of excess pro-oxidant compounds in clinically relevant blood produ

95 We demonstrate that IH creates a pro-oxidant condition that reduces the Tbr2(+) neural pr

96 Exposure of cells to pro-oxidant conditions in culture led to a greater inhib

97 enase-1 (HO-1) is induced under a variety of pro-oxidant conditions such as those associated with isc

98 s shown that this stimulation is promoted by pro-oxidant conditions that result in increased hepatic

99 tro study suggested that aPL may derive from pro-oxidant conditions, we sought a relationship between

100 ows that CaMKII activity is also enhanced by pro-oxidant conditions.

101 or l-3,4-dihydroxyphenylalanine (DOPA) under pro-oxidant conditions.

102 NRF-1-Tfam binding was augmented under pro-oxidant conditions.

103 ene expression in 3T3 cells are inhibited by pro-oxidant conditions.

104 mixture of vehicle exhaust that comprised of pro-oxidant constituents of exhaust, namely, carbon diox

105 t hydrogen peroxide or the chemotherapy drug/pro-oxidant cyclophosphamide.

106 ethine into profibrotic pantothenic acid and pro-oxidant cystamine, we tested this pathway in the pat

107 rol (RSV) acts either as an antioxidant or a pro-oxidant depending on contexts.

108 Behavior is bimodal antioxidant/pro-oxidant depending on the concentration.

109 APDH at functional residues upon exposure to pro-oxidants diamide and H2O2 Here we hypothesize that r

110 cubation of the cells with azidothymidine, a pro-oxidant drug, significantly improves the limit of de

111 d major intracellular antioxidant, acts as a pro-oxidant during myeloperoxidase-catalyzed metabolism

112 les protects RP from the action of water and pro-oxidants during simmering.

113 atitis by production of nitric oxide-derived pro-oxidants (e.g., peroxynitrite).

114 h alpha-tocopherol levels showed a transient pro-oxidant effect at low temperatures but contributed t

115 cular weight fraction, our results support a pro-oxidant effect due to the catalytic formation of hyd

116 This pro-oxidant effect of antioxidants was, even in the abse

117 evidence that caspases partially mediate the pro-oxidant effect of Bax.

118 responding bell-shaped curves displaying the pro-oxidant effect of flavonols quercetin and kaempferol

119 (and GSH only partially) inhibited the weak pro-oxidant effect of peroxynitrite, which produced litt

120 uced hemolysis, but at high concentrations a pro-oxidant effect on erythrocyte morphology was observe

121 , with phytosterol oleogelators exhibiting a pro-oxidant effect.

122 while demonstrating that it had no perceived pro-oxidant effect.

123 In both assays, pro-oxidant effects at higher lioAW concentrations were

124 tivity toward thiols is a determinant of its pro-oxidant effects in HL-60 cells.

125 s strong antioxidant properties, it also has pro-oxidant effects in the presence of free transition m

126 nt effects, with the largest antioxidant and pro-oxidant effects observed at the higher EGCG concentr

127 re, to circumvent the extracellular in vitro pro-oxidant effects of AA, we loaded HL60, U266, and RPM

128 ASMC with Cu((II))ATSM protected against the pro-oxidant effects of angiotensin II (Ang II) by attenu

129 facts associated with the poor transport and pro-oxidant effects of ascorbic acid (AA).

130 In vitro results have been confounded by pro-oxidant effects of ascorbic acid and an overlapping

131 d, thereby avoiding transition metal-related pro-oxidant effects of ascorbic acid.

132 The proposed anti- and pro-oxidant effects of nitric oxide (NO) derivatives, su

133 Plausible mechanisms for the antioxidant and pro-oxidant effects of trolox and PhC on MP are discusse

134 cant roles in determining net antioxidant or pro-oxidant effects, with the largest antioxidant and pr

135 ther organs because of its bioreactivity and pro-oxidant effects.

136 ly deleterious transition metal ion-mediated pro-oxidant effects.

137 tract, while also considering their possible pro-oxidant effects.

138 ional groups of HD, and kill cancer cells by pro-oxidant effects.

139 reported to kill cancer cells with catalytic pro-oxidant effects.

140 We propose that renal accumulation of pro-oxidant elements such as arsenic and depletion of an

141 esult was mainly promoted by the presence of pro-oxidant elements such as salt, as well as greater he

142 icant metabolic challenge with exposure to a pro-oxidant environment and the increased energy demands

143 of diazoxide are mediated by generation of a pro-oxidant environment.

144 (ROS) through HIF-1-dependent activation of pro-oxidant enzyme genes in addition to reduced transcri

145 peroxidase, but also significantly decreased pro-oxidant enzyme levels, such as iNOS and gp91-phox, t

146 ve stress by favourably interacting with the pro-oxidant enzyme like xanthine oxidase.

147 ing the predominant pathological role of the pro-oxidant enzyme NADPH oxidase 5 (NOX5) in DKD, indepe

148 C to T substitution at position +242) of the pro-oxidant enzyme NADPH oxidase p22phox subunit gene an

149 K pathways, and suppresses the expression of pro-oxidant enzyme via AMPK pathway.

150 se, catalase, glutathione) while suppressing pro-oxidant enzymes (NADPH oxidase, lipoxygenase, cycloo

151 ved.O(2)(-), whereas the inhibitors of other pro-oxidant enzymes were ineffective.

152 ysregulations of the expression of anti- and pro-oxidant enzymes, mitochondrial biogenesis and functi

153 oxidant enzymes, and increased expression of pro-oxidant enzymes.

154 against a high dose of the chemotherapy drug/pro-oxidant etoposide.

155 and n-3 PUFAs), as well as adverse prenatal pro-oxidant exposures that might alter the risk of asthm

156 annot directly alkylate DNA, while retaining pro-oxidant features.

157 a feature of ARDS, and we hypothesized that pro-oxidant forces may contribute to the onset and progr

158 nd with extensive DNA damage, transactivates pro-oxidant genes that contribute to apoptosis.

159 f dsDNA structure towards OH radicals as the pro-oxidants has been utilized as the detection principl

160 Haptoglobin (Hp) binds free pro-oxidant Hb, thereby modulating its harmful effects.

161 o arise from the transient accumulation of a pro-oxidant heme A-Cox1 stalled intermediate.

162 Heme oxygenase (HO)-1 degrades the pro-oxidant heme and generates carbon monoxide and antio

163 in part through increased metabolism of the pro-oxidant heme but that higher levels of HO activity o

164 se (HO) isozymes are thought to detoxify the pro-oxidant heme to the potent antioxidant, bilirubin.

165 mal enzyme that catalyzes the degradation of pro-oxidant heme.

166 te limiting enzyme in the degradation of the pro-oxidant hemin/heme from blood, here we investigated

167 uronal loss due to prolonged exposure to the pro-oxidant hemoglobin, with complete protection at 10 m

168 To understand the efficacy of pro-oxidant hepatic perturbations in Wilson disease, we

169 pression increased after incubation with the pro-oxidant hydrogen peroxide (H(2)O(2)).

170 activation of JNK1 by PEITC was inhibited by pro-oxidants hydrogen peroxide and diamide, although the

171 sly reported that hydroquinone (HQ), a major pro-oxidant in cigarette smoke, foodstuff, and atmospher

172 Because ascorbic acid is a strong pro-oxidant in the presence of transition metals in vitr

173 bic acid, AA) can act as an antioxidant or a pro-oxidant in vitro, depending on the absence or the pr

174 ated monoterpenes (e.g. linalool) may act as pro-oxidants in essential oil.

175 t oxidative stress caused by three different pro-oxidants in normoglycemic conditions.

176 cture, thereby protecting quercetin from any pro-oxidants in the aqueous surroundings.

177 We hypothesized that prolonged exposure to pro-oxidants in vehicle emissions result in behavioral a

178 We observed that prolonged exposure to pro-oxidants in vehicle exhaust increased anxiety-and de

179 er cells were more susceptible to additional pro-oxidant injury through thyroid hormone, which accele

180 and even down regulated when insects face a pro-oxidant insult.

181 We report here that a mild pro-oxidant intracellular milieu induced by either pharm

182 In the absence of pro-oxidant ions in the aqueous phase, lipid oxidation o

183 se (PD) cases, which could contribute to the pro-oxidant iron accumulation that characterizes the pat

184 dent iron elevation in the tissue, increases pro-oxidant iron burden in AD.

185 rriprotoporphyrin IX), a potential source of pro-oxidant iron in bone marrow, on in vitro photodynami

186 manganese as an antioxidant in the midst of pro-oxidant iron.

187 The expression of hsp-16-2 induced by the pro-oxidant juglone and by heat shock was significantly

188 were isolated, and their HCV RNA synthesis, pro-oxidant levels, and resistance to oxidative injury w

189 poptosis might be positively associated with pro-oxidant macronutrients and negatively associated wit

190 lts, the variables were classified as either pro-oxidants (malic acid, p-coumaric acid, and caffeic a

191 t marker CAT and decreased expression of the pro-oxidant marker NOX-4.

192 ed iron storage and import genes, along with pro-oxidant markers such as Cybb, Nos2, and Hif1alpha.

193 g that iron accelerated thrombosis through a pro-oxidant mechanism.

194 dy of literature on the potential utility of pro-oxidant mechanisms in cancer therapy.

195 systematically elucidate the antioxidant and pro-oxidant mechanisms of the main BP scaffolds under ph

196 that both of the AP1 motifs are required for pro-oxidant-mediated activation of the ferritin H gene.

197 ynthesize hydroperoxyacids, which are potent pro-oxidant mediators.

198 Cysteinylglycine is a pro-oxidant metabolite of glutathione and a precursor of

199 Arsenic is a pro-oxidant metallic element.

200 These data underscore the role of a pro-oxidant milieu in chemoresistance of hematopoietic a

201 nes can interact to produce a Duox-dependent pro-oxidant milieu that could increase the pathologic po

202 ree heme in building up defense against this pro-oxidant milieu.

203 ical molecular switch in the transduction of pro-oxidant mitogenic signals.

204 The pro-oxidant molecular mechanisms of reducing sugars on t

205 However, heme is a pro-oxidant molecule capable of propagating reactions le

206 because sympathetic neurons contain several pro-oxidant molecules involved in noradrenaline metaboli

207 They act upstream of pro-oxidant NOX2 NADPH oxidase, ERK1/2 phosphorylation,

208 jor phytocompounds present in clove, acts as pro-oxidant or anti-oxidant depending on its concentrati

209 h can be suppressed either by treatment with pro-oxidants or by co-deletion of Yap.

210 leukemic cells from Eu-TCL1 mice lacking the pro-oxidant p66Shc adaptor, which develop an aggressive

211 rrelations, or the lack thereof, between the pro-oxidant parameters and the redox potentials, antioxi

212 e state of erythroid progenitor cells by the pro-oxidant Paraquat reversed the effect of UCP2 deficie

213 We concluded that pro-oxidant perturbations were uniquely effective for ce

214 MK-801 had a pronounced pro-oxidant potential, and when administered in combinat

215 xidants, in general, have been shown to have pro-oxidant potential, the pro-oxidant chemistry of dihy

216 atory shear causes a sustained activation of pro-oxidant processes resulting in redox-sensitive gene

217 hypothesized to be caused either by enhanced pro-oxidant production or decreased levels of antioxidan

218 xidized glutathione and a 3-fold increase in pro-oxidant production.

219 ells from cell killing as well as suppressed pro-oxidant production.

220 Low cholesterol efflux capacity values, pro-oxidant/proinflammatory HDL particles, and low HDL l

221 s, reduced macrophage parasite burden, while pro-oxidants promoted it.

222 However, ascorbic acid also has pro-oxidant properties and may cause apoptosis of lympho

223 d with oxidative stress, possibly due to the pro-oxidant properties of beta-amyloid present in the se

224 The pro-oxidant properties of ethanol may thus act independe

225 Ascorbic acid, known to potentiate the pro-oxidant properties of iron, was also capable of mark

226 carcinogenesis and implicated pheomelanin's pro-oxidant properties that act through the generation o

227 his gene therapy strategy exploits the toxic pro-oxidant property of methylselenol, which is released

228 However, whether pro-oxidants protect from PC remained unclear.

229 mutase 1 and catalase, and activation of the pro-oxidant protein kinase C isoform beta-II (PKCbetaII)

230 involving REDD1, an mTORC1 inhibitor and the pro-oxidant protein TXNIP.

231 iomarkers for assessing stress, toxicity and pro-oxidant quality of chemicals and aquatic environment

232 iomarkers for assessing stress, toxicity and pro-oxidant quality of chemicals and aquatic environment

233 complexes can catalyze both antioxidant and pro-oxidant reactions, whereby the disparate reactivity

234 s species correlate well (r=0.9946) with the pro-oxidant reactivity manifested by flavonoids in the p

235 An assay for the pro-oxidant reactivity of natural products is hence prop

236 on are due to the increasing contribution of pro-oxidant relative to the antioxidant reactions.

237 is type of surgery and represent a potential pro-oxidant risk for oxidative damage.

238 The GSEs play a dual antioxidant/pro-oxidant role in vivo according with the cellular ant

239 Due to the unique pro-oxidant role of ascorbate in tumor environments, AA-

240 posing these functions, it may also assume a pro-oxidant role under some conditions.

241 , we show that combining GLN starvation with pro-oxidants selectively kills GLN addicted cells.

242 These findings enhance our understanding of pro-oxidant selectivity and show how definition of the p

243 glucocorticoid receptor (GR) and downstream pro-oxidant signaling.

244 es an overproduction of pro-inflammatory and pro-oxidant signals.

245 Imexon, a pro-oxidant small molecule, has antitumor activity in pr

246 The pro-oxidants sodium arsenite, cadmium chloride, and hydr

247 in II type 1 (AT(1)) receptor antagonists on pro-oxidant species observed in the pathogenesis of athe

248 the enzyme myeloperoxidase that produces the pro-oxidant species, hypochlorous acid (HOCl).

249 Thus, depending on the pro-oxidant species, the level and duration of the oxida

250 nate the soft Cu(I) cation and thereby yield pro-oxidant species.

251 Puma, and Noxa) have been shown to induce a pro-oxidant state at mitochondria (1-4).

252 roteolysis is triggered during the renal I/R pro-oxidant state by a still unknown mechanism, which mi

253 vulnerable to oxidative stress owing to the pro-oxidant state generated during melanin synthesis, an

254 ligo is thought to be instigated by a highly pro-oxidant state in the epidermis.

255 Inducing a pro-oxidant state similar to that in NGF-deprived, wild-

256 by an arginine-deficient and highly specific pro-oxidant state, with elevated levels of methylated ar

257 w dose rate exhibited a shift towards a more pro-oxidant state.

258 Next, pro-oxidant stimulation of the cell wall integrity pathw

259 in its nuclear translocation in response to pro-oxidant stimuli and that the importin alpha-beta het

260 ubject to hyperlipidaemic, inflammatory, and pro-oxidant stressors.

261 ed with cardiovascular disease are linked to pro-oxidants such as advanced glycation end products (AG

262 an be induced in cultured cells treated with pro-oxidants such as tert-butylhydroquinone, 2,3-dimetho

263 As a pro-oxidant, tBHQ regulates the expression of cytoprotec

264 Treatment of KB cells with the lipid pro-oxidant tert-butyl hydroperoxide induced transient i

265 urposes, we also examined the effects of the pro-oxidant tert-butyl-hydroperoxide (TBHP) and of the d

266 Here, we report that the pro-oxidant, tert-butyl dihydroquinone (BHQ), modulates

267 use NOS enzymes produce nitric oxide (NO), a pro-oxidant that can damage neurons.

268 s a potent antioxidant and can also act as a pro-oxidant that induces oxidative stress on the vascula

269 may contribute to the role of ascorbate as a pro-oxidant that is potentially capable of loosening the

270 ere metabolised during storage, and acted as pro-oxidants that promoted lipid oxidation in both high

271 Overall, the study showed which pro-oxidants that should be inhibited or removed to succ

272 tion in combination with ascorbate and other pro-oxidant therapies.

273 While methylated spirits are already a known pro-oxidant, these data indicate that eucalyptus oil may

274 in albumin oxidation, and albumin acts as a pro-oxidant; this promotes oxidative stress and inflamma

275 n renders cells susceptible to hydroperoxide pro-oxidants, though this type of sensitivity is specifi

276 ld be used to trigger release of copper as a pro-oxidant to increase oxidative stress or as a tool to

277 pherol can act either as an antioxidant or a pro-oxidant to inhibit or facilitate, respectively, lipi

278 We next treated patient cells with pro-oxidants to mimic the oxidative stress associated wi

279 mestic cats appear to have greater levels of pro-oxidant trace elements, as compared to dogs and wild

280 so reports of dihydrolipoic acid acting as a pro-oxidant under certain circumstances.

281 herol (alpha-TOH) has been found to act as a pro-oxidant under many in vitro conditions.

282 In this work, we show that a pro-oxidant vitamin K precursor [menadione sodium bisulf

283 cent cells could help define new markers and pro-oxidant vulnerabilities, drawing analogy to what is

284 nsitivity of the mutant to exogenously added pro-oxidants, we infer that the reactive oxygen species

285 itin heavy chain (ferritin H) was induced by pro-oxidants, which is a part of cellular antioxidant re

286 lavonols, morin and rutin were progressively pro-oxidant, while 7-hydroxyflavone and hesperetin were

287 known regarding the response of aconitase to pro-oxidants within intact mitochondria.