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1 s, vector-borne diseases are complex 'wicked problems'.
2 ions; however, few data exist regarding this problem.
3  third-generation TKIs largely mitigate this problem.
4  analogous to solving the traveling salesman problem.
5  virus (HPV) infection is a growing clinical problem.
6 of the whole chromatin polymer is an inverse problem.
7 ies including bone loss remain a significant problem.
8  often depicted as one big dark conservation problem.
9 ate cervical cancer as a major public health problem.
10 uggesting eDNA method reliability is not the problem.
11  harsh treatments is an important industrial problem.
12 g a persistent cytochrome P450 3A4 induction problem.
13 g the evolution of complex traits is an open problem.
14 g is an effective strategy to alleviate this problem.
15 ion PCR, ePCR) allows the mitigation of this problem.
16 ood undernutrition, a pressing global health problem.
17  monolayers push on carbon fibers as a model problem.
18 PR technology seems likely to alleviate this problem.
19  was found to be a significant public health problem.
20 y appropriate for solving the authentication problem.
21 he key to completely addressing the clogging problem.
22 nal gradients in diversity can overcome this problem.
23 f statistical approaches for addressing this problem.
24 der the curve (AUC) of 0.95, for the 8-class problem.
25 st learning system that addresses the memory problem.
26 roximations to evaluate this solid mechanics problem.
27 icrobial resistance, a serious global health problem.
28          Male factor infertility is a common problem.
29 he maximum possible power for this inference problem.
30 han 13 nm in diameter, are the source of the problem.
31 software platforms have also exacerbated the problem.
32 t data across single-cell atlases is an open problem.
33 (Mtb) infection and is a major public health problem.
34  (STEMI) remains a significant global health problem.
35  matter with applications in grand-challenge problems.
36  as well as several other key stereochemical problems.
37 ometry is a promising solution to macroscale problems.
38 ogether to advance the field and solve these problems.
39 is correlated with psychiatric and cognitive problems.
40  to solve the resulting bilevel optimization problems.
41 tion of plant development for solving future problems.
42 d to whether or not the child has depressive problems.
43 hen confronted with "creeping" environmental problems.
44 in the associated incremental or decremental problems.
45 ting platforms to solve computationally hard problems.
46 ange multiplier optimization for constrained problems.
47 portance in addressing serious public health problems.
48 d microfluidics for single cell analysis met problems.
49 d with a risk of other associated ophthalmic problems.
50  systems and a total of 2,826 protein design problems.
51 temporary structure-electrochemical activity problems.
52 re of common interest in many health-related problems.
53 cheap oil, is creating serious environmental problems.
54 ial dysmorphisms, behavioral and psychiatric problems.
55 s tailored for patients with multiple health problems.
56 creening has the potential to mitigate these problems.
57 e problems, but weakly or not at all to code problems.
58 ability of real applications with large-size problems.
59 roach in such situations, but is not without problems.
60 order associated with physical and cognitive problems.
61 e robust classification of pediatric anxiety problems.
62 benefit of reducing potential immunogenicity problems.
63 ed with legal, interpersonal, and employment problems.
64 aft dysfunction constitute some of the major problems.
65 raction data are key to the solution of this problem, a solution that also will support the improveme
66 rasite Trypanosoma cruzi, is a public health problem affecting 6 to 8 million people, mainly in Latin
67  Acute kidney injury (AKI) is a major health problem affecting millions of patients globally.
68       Heart failure is a major public health problem affecting over 23 million people worldwide.
69                            DGF is a relevant problem after kidney transplantation; sufficient micrope
70                         Here we approach the problem analyzing the evolution of intracellular and ext
71 to study the oligonucleotide copy unevenness problem and show that the two paramount sources of bias
72 ize our problem as an integer linear program problem and solve it using the PuLP package and the stan
73 ed the problem as random variable estimation problem and studied the convergence of the estimator, de
74 raumatic stress disorder, mood disorders, GI problems and chronic fatigue.
75  Arabidopsis thaliana avoids these practical problems and has provided fundamental understanding of p
76  and cut-off scores to measure mental health problems and other common risk factors.
77 ecise weight updates can lead to convergence problems and slowdown of on-chip training.
78 ing' can explain the circumpolar 'Divergence Problem', and discuss implications on the terrestrial ca
79 ckin models that overcome the overexpression problem, and have generated high depth RNA-sequencing on
80 inical information, identify therapy-related problems, and develop therapy-related action plans.Propo
81 ncluding fair/poor oral health status, mouth problems, and teeth problems, compared to people without
82                                Mental health problems are common among caregivers, however, professio
83                                        These problems are compounded in the literature because studie
84                            Not all computing problems are created equal.
85                       However, an additional problem arises when the nature of the spectroscopic info
86                In addition, we formalize our problem as an integer linear program problem and solve i
87 oding will only worsen, we must reframe this problem as one that will disproportionately impact peopl
88                           Here we framed the problem as random variable estimation problem and studie
89 hraquinone dyes pose a serious environmental problem as their reinforced structure makes them difficu
90 l dication (UO(2)(2+)) remains a challenging problem, as few rational approaches are available for mo
91             The fossil record is key to this problem, as it provides data on repetitive trait evoluti
92          This review provides a refresher of problems associated with generating numbers that describ
93                       Out-of-pocket cost per problem-based visit rose by $9.4 (31.5%).
94 ttempted to solve Compound Remote Associates problems before, during and after stimulation.
95 arning has been applied to cell segmentation problems before, our approach is fundamentally innovativ
96 ave unique causal processes underlying their problem behavior and are at a particularly high risk for
97 ntional laboratories for a range of research problems beyond photocatalysis.
98        Cancer metastasis poses a challenging problem both clinically and scientifically, as the stoch
99 ased on this, we deduce that quantum control problems both for open and closed systems are in general
100  is intended to solve this collective action problem, but is likely insufficient.
101 ntrol via electric fields would resolve this problem, but previous methods(7-9) relied on transducing
102 o address therapeutic(3,4) and industrial(5) problems, but a substantial obstacle is the myriad of un
103 ologies have been developed to address these problems, but each possesses limitations that constrain
104 nguage system responded strongly to sentence problems, but weakly or not at all to code problems.
105                        Here we approach this problem by adapting the random-dot motion discrimination
106                We provide a solution to this problem by deriving formulae for the empirical curves th
107             This study seeks to address this problem by introducing new, to our knowledge, fluorescen
108 tem was used to overcome the Poisson loading problem by sorting for droplets containing a single red
109      We approximately solve high-dimensional problems by combining Lagrangian and Eulerian viewpoints
110 of miniature size can mitigate some of these problems, by coating it with biocompatible material for
111             It has long been known that this problem can be alleviated in vivo if proteins start fold
112                       Here we show that this problem can be circumvented by assembling a functional r
113                        We describe how these problems can be resolved with a slightly modified form o
114  suggests that species once considered major problems can decline over time.
115     Schistosomiasis is a major global health problem caused by blood-dwelling parasitic worms, which
116 ral health status, mouth problems, and teeth problems, compared to people without vision impairment.
117                         To explain how these problems develop, the neuroimmune network hypothesis sug
118 f corn rotation for mitigating Bt resistance problems did not differ significantly between crop-repor
119 s solve multiple reinforcement learning (RL) problems differing in structural or sensory properties.
120 eliminate cervical cancer as a public health problem during the 21st century.
121 s, slowness), and psychological or cognitive problems (eg, cognitive decline, depression, anxiety).
122                                         Many problems exist within the myriad of currently employed s
123   These results suggest that speech-in-noise problems experienced by older HI listeners are not neces
124 design (CPD) can address the inverse folding problem, exploring a large space of sequences and select
125 rch efforts towards one of the most pressing problems facing our planet.
126                             For this type of problem, fluorescence imaging is usually the primary too
127   This study develops two approaches to this problem for a critical floating tree-ring chronology fro
128 late the direct transmission inference (DTI) problem for inferring transmission trees that support mu
129 symmetric C-H oxidation a generally unsolved problem for nonenzymatic systems.
130  Age-related hearing loss (ARHL) is a common problem for older adults, leading to communication diffi
131 ching") under heat stress has become a major problem for reef-building corals worldwide.
132                                A fundamental problem for the evolution of pregnancy, the most special
133 de (nt) pose an architectural and logistical problem for the two domains to interact with their respe
134            This remains a particularly acute problem for triploids, which produce desirable seedless
135 azard can lead to physical and mental health problems for nurses and may also affect the nursing care
136 ver, the lack of robustness assessment poses problems for their application across institutions and f
137 te the stability of data results relative to problem formulation, data cleaning, modeling decisions,
138 at each step of its process: recognizing the problem, generating appropriate solutions, and the socia
139 ombination of painful conditions and alcohol problems had the largest effect size on mortality, with
140 ions of deep learning networks to real-world problems have become ubiquitous, our understanding of wh
141 as been successful, but residual significant problems have hindered the opportunity to take full adva
142 have emerged to address more diverse genetic problems, holding promise of boosting genetic research i
143 unction (neonatal bradycardia/apnea, feeding problems, hyperactive startle reflex), severe postnatal
144 pervisor stepped aside and workers discussed problems, ideas, and goals regarding their work (vs.
145                              The fundamental problem in axon growth and guidance is to understand how
146 espan and the rate of aging are set is a key problem in biology.
147  by clonal evolution is arguably the biggest problem in cancer therapy today.
148 ss (alopecia) (CIA) remains a major unsolved problem in clinical oncology.
149             Eye infection is a public health problem in developing countries including Ethiopia.
150 gulation of organ structure is a fundamental problem in developmental biology.
151 FDR) of spectral identification is a central problem in mass spectrometry-based proteomics.
152                      We have approached this problem in mouse retina by analysing the kinetic differe
153            This study addresses an important problem in neurology, distinguishing tremor and ataxia u
154 trointestinal symptoms are a common clinical problem in pediatrics.
155  infected (demographic) data is an important problem in population dynamics.
156 y of results, since repeatability has been a problem in studies utilizing functional magnetic resonan
157 medical implants and devices is a ubiquitous problem in the field.
158 standing swarm behavior to a decision-making problem in the mammalian immune system, namely effector
159                                     A common problem in this area is selection of the number of clust
160 ASM) problem to the single net routing (SNR) problem in VLSI chip layout.
161  because people seem capable of representing problems in an infinite number of ways.
162 o solve various quantitative and qualitative problems in analytical chemistry.
163 ics, the application of informatics to solve problems in chemistry, has increasingly influenced predi
164 hat brain structure is associated with sleep problems in children, and that this is related to whethe
165 nction estimation of arbitrary computational problems in gate-model quantum computers.
166 of microcephaly and associated developmental problems in infants born to women infected with ZIKV dur
167  one of the most fascinating and challenging problems in modern biology, and tracing the evolution of
168  AN loss is widely expected to cause hearing problems in noise, known as "hidden hearing loss," but e
169 ol may contribute to the prevalence of sleep problems in older age, particularly for men.
170 nds into a staple of eigenvalue and spectral problems in physics and chemistry.
171 ses will also exacerbate other environmental problems in temperature-sensitive ecosystems (e.g., cora
172 luid overload is one of the most challenging problems in the care of critically ill patients with oli
173 uberculosis (PTB) is one of the major health problems in the elderly population, causing significant
174  for simplicity)-developed and used to solve problems in the fields of chemistry, materials science,
175 mely, convolutional neural networks to solve problems in the initial steps of the common pipeline for
176  infant TL that predicts emerging behavioral problems in the next generations.
177 tion and inflammation all of which are major problems in tooth restoration.
178 s application is still limited to simplified problems in two dimensional space or straight motions.
179 t been considered to explain the 'Divergence Problem' in dendroclimatology; a decoupling of tree grow
180               Unfortunately, RAR causes many problems, including (1) bias from temporal trends, (2) i
181 eported 90%-150% greater odds of oral health problems, including fair/poor oral health status, mouth
182 s been employed in solving several important problems, including mapping epitopes, following protein
183 ces to target mobility and physical activity problems, individually prescribed by a physiotherapist a
184 uster synchronous solution by decoupling the problem into a number of independent blocks and assessin
185 m that maps the two-dimensional (2D) elastic problem into that of nonlinear interaction of elastic ch
186 lator is validated against several benchmark problems (involving, e.g., Fickian and Nernst-Planck dif
187       We find that this curve reconstruction problem is analogous to solving the traveling salesman p
188 research priorities to address the carbonate problem is essential if this technology is to become a v
189                                       Such a problem is extremely challenging because compound attrib
190 es are caused by genome rearrangements, this problem is often posed as minimization of the number of
191                                          The problem is particularly challenging for proteins with di
192                                 Herein, this problem is resolved by chemically installing extended pa
193                        One way to avoid this problem is to tailor windows according to a contrast tha
194 al background, one of the important unsolved problems is a direct experimental determination of the n
195 communication in the context of coordination problems is scarce.
196                 One means to avoid the above problems is using readily available native DNA.
197 e these operations to solve the mathematical problem Learning Parity with Noise (LPN).
198 as been undertaken with actigraphy, although problems may occur in classifying chronotype.
199 enefit with this type of resection, and many problems must still be solved.
200 nd mitigating the growing energy consumption problem, new building materials and technologies could p
201         For that, we solve the electrostatic problem of a conducting hyperboloid with an elliptical w
202 operative traits is a viable solution to the problem of antimicrobial resistance.
203 mer alphabet turns the notoriously difficult problem of assembling centromeres from reads (in the nuc
204 e nucleotide alphabet) into a more tractable problem of assembling centromeres from translated reads.
205                                          The problem of assessing associations between multiple omics
206 development of deep learning approaches, the problem of catheter assessment is far more solvable.
207 ter counter device design that overcomes the problem of constriction clogging while capable of operat
208 lthough research conducted online solves the problem of data collection, the paucity of internet acce
209 each subject, overcoming the intelligibility problem of deep-learning methods.
210 m (K) metal anodes suffer from a challenging problem of dendrite growth.
211 rs of chimpanzees (Pan troglodytes) solved a problem of dynamically coordinating their actions for ac
212 ransport in DNA molecules is a long-standing problem of fundamental importance across disciplines(1,2
213    Link prediction in a complex network is a problem of fundamental interest in network science and h
214 learning framework (Keras) is applied to the problem of image segmentation using a U-Net.
215 onstrate that in vivo k (cat)s can solve the problem of inconsistent and low-coverage parameterizatio
216       With food allergy being a major health problem of increasing concern, understanding the potenti
217                                          The problem of low Raman scattering was overcome by trapping
218 to be equivalent to those of the constrained problem of minimizing the loss subject to a unit norm co
219 e a globally optimal solution to the NP-hard problem of minimizing the total number of intra-group ne
220                               The escalating problem of obesity and its multiple metabolic and cardio
221 rithms and found all of them suffer from the problem of overfitting.
222 y limit their ability to address the broader problem of polysubstance use.
223 e strategy in proteomics that alleviates the problem of ratio distortion caused by peptide cofragment
224                                          The problem of single individual haplotyping (SIH) was first
225                    In this work, I study the problem of storing associations between analog signals i
226        Finally, the vibration and eigenvalue problem of the actuated nano-manipulator subjected to el
227 ry teams to solve the pressing public health problem of venous thromboembolism.
228 loss model that systematically addresses the problems of choosing event costs and selecting represent
229                              To mitigate the problems of crystallization of raisins during shipping,
230 otential impact of quantum computers on real problems of interest.
231  decomposition of a large-scale LIP into sub-problems of low complexity and the fusion of the sub-pro
232 re was a significant indirect effect of peer problems on adolescent depression through nucleus accumb
233  strategies for preventing and reducing this problem, perspectives differ, hindering the development
234                     Here, we solve this open problem, presenting a comprehensive theory of five ratio
235           Our findings solve a long-standing problem, providing a new insight into the physics of mag
236 y useful for a variety of library generation problems, ranging from protein engineering attempts that
237 eological mystery concerns the missing xenon problem, referring to the abnormally low concentration o
238  field of drug delivery have been related to problems regarding toxicity and immunogenicity, escalati
239 anoengineering successfully mitigate several problems related to volume expansion of alloying anodes.
240 , role limitations caused by physical health problems) remained statistically significant (P < 0.01).
241 t frequent IEIs sharing common main clinical problems requiring full attention during the transitiona
242 mputational resources to handle an oversized problem, security and privacy concerns, and the interest
243 he uncertainty space in phenotype prediction problems, since the probabilistic parameterization of th
244  of low complexity and the fusion of the sub-problem solutions to form the solution to the original L
245 lso sharpens our understanding of the design problems solved by evolution in nature.
246       To study this type of general physical problem solving, we introduce the Virtual Tools game.
247  other animal behaviors, which suggests that problem-solving is a stable, general trait in wild spott
248  wild-caught great tits (Parus major) with a problem-solving task and showed that performance was wea
249  labeling approaches combine to constitute a problem-solving toolbox that enables mass spectrometry a
250 In general, the estimates of reliability for problem-solving were comparable to estimates from the li
251 sted the causal role of this brain region in problem-solving, by applying High Definition Transcrania
252 his question in the context of collaborative problem-solving, which is central to a variety of domain
253 ee methods have been proposed to address the problem: sparse label-noise-robust logistic regression (
254                              To address this problem, ten healthy US military veterans (mean age = 32
255  is often faster and can handle more diverse problems than other methods for musculoskeletal simulati
256 se 2019 (COVID-19) is a global public health problem that has already caused more than 662,000 deaths
257 anizes its architecture when it divides is a problem that has fascinated researchers for almost 150 y
258    This task can be considered a text mining problem that requires reading a lot of academic document
259 ionally, the scientific issues and technical problems that hinder further development of these materi
260      The software can handle a wide range of problems that interest biomechanists, including motion t
261                             To minimize this problem, the imported cystine is rapidly reduced.
262                               To avoid these problems, this work attempts to introduce CsPbBr(3) into
263  distinct and more challenging computational problem-this is what the brain must actually accomplish
264                                We study this problem through the lens of normative, optimization-base
265 h care covers the most prevalent oral health problems through an agreed-on set of safe, quality, and
266 ed to solve other combinatorial optimization problems through polynomial-time mapping.
267 m that the model generalizes to a real-world problem, thus providing an important step toward underst
268 satisfied constraints and re-casts the given problem to a new Ising Hamiltonian.
269 cation where barriers are expected to pose a problem to efficient DNA bubble migration.
270 reduce the approximate string matching (ASM) problem to the single net routing (SNR) problem in VLSI
271                         Here we address this problem using an inorganic chemical approach, whereby mu
272                     Plants can mitigate both problems, via Se biofortification and phytoremediation.
273                               To remedy this problem, we attempt to disentangle confounders from true
274                              To address this problem, we describe a diversity of approaches to quanti
275                              To address this problem, we designed a highly sensitive sensor built on
276                              To address this problem, we designed a sensing platform based on poly(et
277                               To tackle this problem, we engineered an HA tag onto Cx26 or Cx30 subun
278                              To address this problem, we generalized such models by adopting a nonpar
279                             To overcome this problem, we have developed an automated and fast fractio
280 rtial confinement fusion (ICF) as a test-bed problem, we model a one-dimensional semianalytic numeric
281                               To address the problem, we propose a Boolean network inference algorith
282                                    For large problems, we also develop an approximate coarse-graining
283                             To address these problems, we propose a novel method, Met-predictor, to p
284 e is used to address the imbalanced learning problem when training the deep neural network.
285 nature, echolocating bats experience similar problems when searching for food, especially if their fo
286                                  This causes problems when the biosensor cannot be easily replaced (e
287 dynamics simulations and describe tricks and problems when using them in machine learning for excited
288 ations can be viewed as language recognition problems where both languages and automata recognizing t
289                               Tackling these problems will benefit from a more explicit and concerted
290                                Solving these problems will need additional work before efficacious pr
291                                      A major problem with such mouse models is that bnAb expression o
292 wever, recent work has highlighted potential problems with common approaches to evaluating and interp
293                There are serious theoretical problems with the free-energy principle model, which are
294 n of the PHI-base project, and some existing problems with the PHI-base curation process.
295 urces of systematic uncertainty and resolves problems with typical background-correction schemes.
296 viruses represent a widespread global health problem, with limited treatment options currently availa
297        In the Wireless Localization Matching Problem (WLMP) the challenge is to match pieces of equip
298               It is one of the public health problem worldwide and is the principal cause of parenter
299 CE HIV continues to be a major public health problem worldwide, with over 36 million people living wi
300                 A potential solution to this problem would be for an animal to learn the values for s

 
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