ライフサイエンスコーパス: problematic

1 ke the fuelling prior to northward departure problematic.

2 n a clinical microbiology laboratory remains problematic.

3 and the synthesis of its derivatives can be problematic.

4 but inconsequential "passenger" mutations is problematic.

5 y of matched donors and toxic effects can be problematic.

6 liest stages of test development can also be problematic.

7 a, so attributing observed changes to SST is problematic.

8 of potential stressors to species of concern problematic.

9 he diagnosis of pleural tuberculosis (TB) is problematic.

10 inferences on effective beta-lactam choices problematic.

11 the maintenance of genomic integrity appears problematic.

12 ut that early retention on treatment remains problematic.

13 the quantitative interpretation of TIRF data problematic.

14 tion, which philosophers of science consider problematic.

15 ical diagnosis of post-traumatic dementia is problematic.

16 using two-hybrid systems has therefore been problematic.

17 rt in small isolated populations may be more problematic.

18 nd, their installation and implementation is problematic.

19 nal or external validity in isolation may be problematic.

20 DR) control of some popular methods has been problematic.

21 entifying this characteristic as potentially problematic.

22 clinical use of GSK3 inhibitors potentially problematic.

23 size three-dimensional photonic crystals are problematic.

24 ions, and drug interactions are particularly problematic.

25 nt in simultaneous intracellular recordings, problematic.

26 tion and scan tolerance were not reported as problematic.

27 art failure guidelines to the NMD population problematic.

28 he meaning of "missing heritability" becomes problematic.

29 Early nonadherence is especially problematic.

30 imental timelines where blood degradation is problematic.

31 Yet truly quantitative TIRF remains problematic.

32 infection (LTBI) treatment regimens has been problematic.

33 tric studies using the Nicholson approach is problematic.

34 ssible mushroom body homolog in Brachyura as problematic.

35 after which a poor signal-to-noise ratio is problematic.

36 erpretation of rare genetic variants remains problematic.

37 rate and identify which scent-pollutants are problematic.

38 intravenous (18)F-FDG when venous access is problematic.

39 ene trees and species trees are persistently problematic.

40 torically it has been viewed as biologically problematic.

41 and time lag from sampling to results remain problematic.

42 processes that are otherwise inefficient or problematic.

43 proteins, and under-treatment is common and problematic.

44 extensive NANP and NVDP repeats, has proven problematic.

45 on of contaminants from the electrode is not problematic.

46 infectious and hematologic toxic effects are problematic.

47 rge depth interval, such mixing is even more problematic.

48 clared and illegal fisheries is persistently problematic.

49 CMV disease, specifically pneumonia, remains problematic.

50 roblematic, 8% were engaged and 32% were non-problematic.

51 porates a 1,2-cis-alpha-glycosidic bond; the problematic 1,2-trans-galactosidic bond, Gal-beta-(1 ->

52 s; 88.64% Male), 30% were addicted, 30% were problematic, 8% were engaged and 32% were non-problemati

53 r sexual risk taking, mental ill health, and problematic alcohol use (ORs of more than three to six),

54 Problematic alcohol use (PAU) is a leading cause of deat

55 mographics, current well-being and past-year problematic alcohol use of past-year ayahuasca users and

56 speaks to the profound impact of marriage on problematic alcohol use.

57 ults corroborate previous studies, reporting problematic and addicted gamers show poorer health outco

58 gamer types (i.e., non-problematic, engaged, problematic and addicted) and (3) the predictive power o

59 electrochemical reaction products is clearly problematic and bears further investigation.

60 to effectively resolve MG activation can be problematic and can lead to chronic inflammation, a cond

61 anslates into decision-making and policy are problematic and can lead to unintentional overexploitati

62 tifunctional sensors with these features are problematic and challenging to accomplish.

63 erologous expression in microbial systems is problematic and instability and aggregation of recombina

64 determining susceptibility to polymyxins is problematic and lengthy.

65 nical VTs during ablation procedures remains problematic and may be in part responsible for VT recurr

66 black students are more likely to be seen as problematic and more likely to be punished than white st

67 bacteria, however, the method has been more problematic and no consensus has emerged for how to best

68 dult neurons, in vitro or in vivo, have been problematic and not translatable to human patients.

69 ility to obtain sufficient tissue samples is problematic and requires invasive approaches that pose i

70 arching of isotopically labelled PTMs can be problematic and we frequently find that only one, or nei

71 chievement, however, has proved to be rather problematic, and current realizations display a number o

72 Consequently, peak overlap was problematic, and it was not always possible to integrate

73 t management in hemodialysis patients may be problematic, and no formal recommendations on hemodialys

74 e isolated feather's identification has been problematic, and the fossil was considered either a prim

75 ustainable workforce and service development problematic, and the unavailability of specialised cance

76 their proliferation, which might explain its problematic anti-neurogenic or cognitive side-effect.

77 We identify problematic areas throughout the Science, Technology, En

78 d systems, and multiple realizability are as problematic as claimed in the target article, and we pre

79 Hyperalgesia is particularly problematic as further opioid prescribing is largely fut

80 This is potentially problematic as most H3N2 viruses currently circulating i

81 This knowledge gap becomes more problematic as new approaches to modifying this ecosyste

82 PA1 (hTRPA1) protein in cells and tissues is problematic as rigorous antibody validation is lacking.

83 This can be problematic as the two species likely belong to differen

84 Furthermore, reaction scale up is often less problematic as this is addressed at the inception of the

85 orally neutral as toward insects or flowers, problematic as toward race or gender, or even simply ver

86 esence of blood during ophthalmic surgery is problematic, as it can obstruct a surgeon's view of the

87 This presentation is problematic, as many data distributions can lead to the

88 lopment, our approach can explain previously problematic aspects of large-scale forest mortality, suc

89 If these problematic assumptions were questioned, information the

90 Patients with problematic asthma follow distinct illness trajectories

91 Problematic asthma patients with unfavorable long-term d

92 ectories of severe exacerbation rates among "problematic asthma" patients and develop a risk score to

93 exacerbation rates over five years for 177 "problematic asthma" patients presenting to a specialist

94 comprehensive analysis of the literature is problematic because CE values of at least 99.7%, and pre

95 This is highly problematic because decision makers should only countena

96 So far this is problematic because established organometallic Ru precur

97 The long-enduring coding metaphor is deemed problematic because it imbues correlational evidence wit

98 However, relying on observers' reports is problematic because it is difficult to know whether the

99 explain experiences of aesthetic pleasure is problematic because it is founded on a mechanistic Enlig

100 y classical genetics, however, is inherently problematic because it is impossible to knock them out.

101 ng the roles of individual NSPs in humans is problematic because neutrophils are end-stage cells with

102 However, the use of relaxin is problematic because of a short half-life.

103 ls in countries such as India is potentially problematic because of high antibiotic use, overcrowding

104 ing of complex, heterogeneous systems may be problematic because of sampling hardware limitations, an

105 study of the formation of TCR repertoires is problematic because of the difficulty in performing inve

106 Such studies, however, are inherently problematic because of the discovery of excessive false

107 perform catalytic functions is particularly problematic because of the low efficiency of nonenzymati

108 environment, the presence of arsenic can be problematic because of the potential for increased mobil

109 pted this manifestly beneficial strategy and problematic because the comparative methods of evolution

110 This seems problematic because the reaction of CH4 and water to gen

111 predictors of coemitted pollutants, which is problematic because these pollutants may not be indicato

112 However, the no-report paradigm is problematic because, even in the absence of report, subj

113 Targeting Gq directly to test this is problematic, because cardiac myocytes have many Gq-coupl

114 Testing can be problematic, because the CLSI does not recommend the tes

115 form diagnostic classification of clinically problematic behavior and the clinical trajectories of di

116 tently identify different rates and types of problematic behavior in boys and girls, there has been l

117 nt vulnerability factor for the emergence of problematic behaviors and a range of psychopathologies.

118 criteria stated in the table and text boxes; problematic categorization and confounding of sexual ori

119 accumulation or disposal of in landfills is problematic, causing environmental issues.

120 8.6% of these cell lines were on the list of problematic cell lines, whereas only 3.3% of the cell li

121 rchers to cell lines that are on the list of problematic cell lines, which is maintained by the Inter

122 s is associated with a lower reported use of problematic cell lines.

123 I point to the problematic characterization of rationalization in tradi

124 f C. difficile infection in some of the most problematic clinical strains(3).

125 ectroscopy as a method for identification of problematic compounds and as a valuable aid toward revea

126 libraries, and identify and eliminate these problematic compounds.

127 for scores on items 4-10, which focus on the problematic consequences of drinking (AUDIT-P).

128 Fe(II) -catalyzed oxidation accomplished the problematic conversion of indole into 2-indolinone.

129 amide-derived nitrenoid precursors avoiding problematic Curtius-type rearrangements.

130 enhance efficiency and regioselectivity for problematic cyclopentanone substrates in the C-C activat

131 rticles due to post-publication detection of problematic data.

132 r well-being than comparison groups and less problematic drinking than classic psychedelic users.

133 s of PAU, combining alcohol use disorder and problematic drinking, in 435,563 European-ancestry indiv

134 f more than three to six), and strongest for problematic drug use and interpersonal and self-directed

135 ng of future rewards at age 14 also predicts problematic drug use at age 16, but the neural responses

136 uring reward anticipation at age 14 predicts problematic drug use at age 16.

137 in response to anticipated rewards predicts problematic drug use.

138 e-based molecular mechanisms of promising or problematic drugs have not been investigated at atomic s

139 d active duty soldiers, but diagnosis can be problematic due to biases in self-disclosure of symptoms

140 Deciphering the carbohydrate alphabet is problematic due to its unique complexity among biomolecu

141 scertained newly acquired phenotypes remains problematic due to low DNA recombination efficiency.

142 electronic devices, but their acquisition is problematic due to perceived limitations in atomic force

143 he pro-apoptotic histone H2AX but clinically problematic due to the drug's adverse effects.

144 this organism on a routine basis, which were problematic due to the fastidious nature of the bacteriu

145 interactions in the cellular environment are problematic due to the lack of suitable biophysical tool

146 long enough to encode catalytic functions is problematic due to the low efficiency of template copyin

147 concern, and antiviral chemotherapy remains problematic due to toxicity of available compounds and t

148 in repetitive or homologous regions, can be problematic due to uneven read coverage or genome refere

149 A comparison between studies is problematic, due to differences in the methods employed.

150 gery, pericardial adhesions are particularly problematic during reoperations, as surgeons must releas

151 unders, we observed positive associations of problematic eating attitudes at age 11.5 y with new-onse

152 Problematic eating attitudes in midchildhood seem to be

153 In response to the increasingly problematic emergence of antibiotic resistance, novel st

154 these conditions and gamer types (i.e., non-problematic, engaged, problematic and addicted) and (3)

155 to experimentally identify these potentially problematic entities.

156 isite geometrically defined enamides remains problematic, especially for highly substituted and Z-ena

157 Hg, and Pb), which can make the upstream use problematic, especially for mercury.

158 predictions of shoreline evolution are still problematic even in short-term scenarios (shorter than d

159 elieved to have been murdered and buried, is problematic, expensive in terms of human resource and cu

160 AN) is most often suspected as the cause for problematic fermentations and has major implications for

161 ghlighted the potential for treatment of the problematic fluoroquinolone-resistant MRSA, VRE, and S.

162 ence and evaluating impact on folding can be problematic for amyloid aggregates because a single sequ

163 ding humans, whose persistent infections are problematic for aquaculture and public health.

164 t of custom scripts and pipelines, making it problematic for biomedical researchers.

165 sh are not well defined and therefore remain problematic for cross-species comparisons.

166 Such tremor is especially problematic for dexterous hand movements, yet knowledge

167 s lack of a back and forth can be especially problematic for first-time submitters or those from outs

168 The residual background signals, which are problematic for in situ structural biology, contribute s

169 This is especially problematic for intact proteins, including antibodies, w

170 This is especially problematic for inversions, since there is typically no

171 This could be particularly problematic for metaanalysis where replicability across

172 This procedure is problematic for multisensory speech perception since aud

173 interest followed by complementation remains problematic for obligates and is a highly sought-after g

174 tient reviews posted on online sites appears problematic for periodontal practices, the author urges

175 onents and excessive antigen variability are problematic for pharmaceutical vaccine production.

176 ches from geographical distributions is most problematic for poorly dispersed and highly persistent s

177 line media than in acidic environment may be problematic for practical application.

178 quires expertise, is prone to errors, and is problematic for reproducibility.

179 tcomes, and treatment response has long been problematic for researchers aiming to identify biologica

180 However, shared temporal context may be problematic for selective retrieval of specific memories

181 x instead of a [Formula: see text] efflux is problematic for several reasons: First, the [Formula: se

182 These issues are particularly problematic for students and novice researchers.

183 G4 structures can be problematic for the essential processes of DNA replicati

184 preactivation, which has become particularly problematic for the study of large macromolecular protei

185 This is particularly problematic for thick electrodes and electrodes highly l

186 infections in high transmission settings is problematic for traditional genotyping approaches.

187 positive feedback mechanisms that can prove problematic for traditional probe positioning methods.

188 These definitions are problematic for two reasons.

189 The problematic fossil taxa Halkieria and Orthrozanclus (gro

190 how poorer health outcomes compared with non-problematic gamers.

191 es from increasing in prevalence or becoming problematic (general proactive approaches).

192 It is problematic given the nature of the patient-physician re

193 The monophyly of the so-called "problematic" Gonideinae taxa was supported by all the in

194 include echinoderms, hemichordates and more problematic groups such as vetulicolians and vetulocysti

195 formed DLS perturbations to curb intractably problematic habits.

196 heir delineation of the critical factors are problematic, however.

197 Obtaining crystalline 31 proved problematic, however; thus salt screening was performed

198 olidation provide opportunities to alleviate problematic human memories, we lack a detailed mechanist

199 Using generic language is especially problematic if authors overgeneralize from small or unre

200 d outcome, but this credit assignment may be problematic if stimuli differ on multiple dimensions and

201 HCPs can be problematic if they pose a significant metabolic demand,

202 Administering asparaginase has always been problematic in adults because most general oncologists w

203 We find that Glaser coupling is not problematic in ARGET-ATRP of alkyne-terminated polymers

204 gging and poaching), which become especially problematic in certain developing countries along tropic

205 on international normalized ratio, which is problematic in cirrhosis, and published experience in li

206 False positive tracts, which are especially problematic in clinical studies, have been reduced subst

207 This development is especially problematic in gram-negative bacteria due to the outer m

208 rug-resistant pathogens that are notoriously problematic in hospitals: Pseudomonas aeruginosa, Acinet

209 HAstV infection can be especially problematic in immunocompromised people and infants, whe

210 As a result, HCMV infections are highly problematic in individuals with weakened or underdevelop

211 They are especially problematic in low resource environments where non-fatal

212 imate change, yet its reconstruction remains problematic in many regions.

213 de electrodes during cycling, which is often problematic in mixed alkali cation systems such as K-Na

214 Access to pacemakers and defibrillators is problematic in places with limited resources.

215 This becomes problematic in samples containing (239)Pu, so our aim wa

216 atomic nuclear spins, which is particularly problematic in strained self-assembled dots.

217 This phenomenon is particularly problematic in the biotechnology industry, as production

218 quences in biopolymers, but this is somewhat problematic in the formation of synthetic polymers.

219 of pairwise distance estimates, which can be problematic in the presence of fragmentary sequences.

220 in applying and interpreting statistics are problematic in themselves, and they arguably reflect an

221 This is particularly problematic in ultrafast nanophotonics, including optica

222 g insect pests in soil that are increasingly problematic, in part due to the lack of effective manage

223 sial embryonic stem cells (ESCs) and somehow problematic induced pluripotent stem cells (iPSCs).

224 ive drug discovery for the treatment of such problematic infections is the combination therapy "antib

225 We conclude that a significant source of problematic interpretations in photobiomodulation report

226 ic analysis done by our group identified two problematic issues not coherently described before: (1)

227 e of APE2 is to reverse blocked 3' DNA ends, problematic lesions that preclude DNA synthesis.

228 electrolytes are considered able to inhibit problematic Li dendrites and build safe solid Li-metal b

229 e 634 papers that included RRIDs were on the problematic list.

230 n have many adverse effects, contributing to problematic long-term use.

231 Science fiction notions of altering problematic memories are starting to become reality as t

232 pharmacologically and behaviorally to impair problematic memories.

233 Problematic microfossils dominate the palaeontological r

234 Some problematic missing data methods such as complete case (

235 gand-centric approach taken here overcomes a problematic molecular redundancy of CspC and CspE that l

236 standardization of CMV quantitation remains problematic, mostly due to differences in qPCR amplicon

237 multiple decay processes converge to process problematic mRNAs in eukaryotic cells..

238 cts resulting from translation of damaged or problematic mRNAs.

239 es to be the imprecise, difficult, and often problematic nature of most methods used to measure cell

240 protocol does not require time-consuming and problematic off-chip probe conjugation and washing.

241 t can impart treatment resistance, and cause problematic off-target effects.

242 I propose an additional problematic omission: pride.

243 It unfortunately suffers from problematic operation stability due to CO poisoning on s

244 disturbed males may be at greatest risk for problematic opioid use.

245 long fragments are able to extend paths into problematic or repetitive regions.

246 These studies have revealed potentially problematic outcomes with some fluorinated motifs and ar

247 Yet few studies of decreasing problematic outlets and outlet density have been conduct

248 This limitation is problematic particularly for those compounds with DT50s

249 C6-CD(3)O redirected metabolism away from a problematic pathway, thereby circumventing the time-depe

250 Accordingly, partial 'un-scoring' of the problematic phylogenetic characters was proposed.

251 right deny any suitability of CUR due to its problematic physicochemical properties.

252 For some individuals, problematic pornography use (PPU) is a reason for seekin

253 s inhibitors for the adhesion protein of the problematic Pseudomonas aeruginosa pathogen.

254 sion products (99)Tc and (90)Sr are found as problematic radioactive contaminants in groundwater at n

255 ructure of xanthopterin included, however, a problematic repulsive interaction between C=O and N of t

256 Translation of problematic sequences in mRNAs leads to ribosome collisi

257 population structure in these studies can be problematic since both selection and neutral demographic

258 Ecosystem-dependent theories are problematic since properties unique to an ecosystem may

259 This is potentially problematic, since prior immunity to a scaffold may inhi

260 unately, as we demonstrate empirically, such problematic situations of correlated and linearly depend

261 Problematic sleep disproportionately affects women in po

262 yping array manifest file and can detect all problematic SNPs, including SNPs with wrong RS ID and SN

263 ge of science to lend false credibility to a problematic sociocultural discourse.

264 activation by UndA; these routes obviate the problematic steps of the earlier hypotheses that invoked

265 he blood-brain barrier, while others contain problematic structural moieties.

266 udied in clinical settings where it might be problematic, such as in people with autoimmune diseases.

267 genesis in the absence of lengthy, and often problematic, technical manipulations.

268 bs against glycan epitopes is generally more problematic than against proteins.

269 ent that the coding metaphor has become more problematic than helpful for theories of brain and cogni

270 Such morphing is problematic; the methodological approach used by the exp

271 But rather than these being a problematic time, we've seen synthetic biology blossom a

272 t recent work suggesting that R-loops can be problematic to cells as blocks to efficient transcriptio

273 esirable but are typically nonstructural and problematic to control.

274 CS is problematic to diagnose and may cause significant morbid

275 However, it has proven problematic to genotype STRs from high-throughput sequen

276 isease-causing variation, yet they have been problematic to resolve in reference genomes and genotype

277 However, it has been problematic to test this proposal in living cells becaus

278 onomic activity; however, the bycatch can be problematic to the environment.

279 berculosis, and Mycobacterium leprae, remain problematic today.

280 roots in the Industrial Revolution make it a problematic tool for telling the history of that period.

281 the genomes of four cacti in the especially problematic tribe Pachycereeae, which contains most of t

282 lopment of new clinical strategies to modify problematic trunk motion.

283 roach is time- and labor-consuming, which is problematic upon pandemic proliferation of previously un

284 One of the root causes lies in the problematic vaccine 'cold chain' distribution.

285 We argue that this problematic view, which we call "encodingism," is pernic

286 rapeutic options to provide alternatives for problematic VRE infections.

287 e identification of rare cell types is often problematic, we propose a transfer learning method to ut

288 Goosegrass is a problematic weed species in Florida vegetable plasticult

289 nal and global vegetation simulations can be problematic when analysis units to which parameters are

290 Lack of signal is especially problematic when classes are represented in an unbalance

291 structive analysis of a sample, which can be problematic when dealing with artefacts.

292 e preselection of specific limits but may be problematic when several experimental conditions are tes

293 oratories in the United States; this becomes problematic when the collective scientific effort needs

294 riable selection in inferential modelling is problematic when the number of variables is large relati

295 e of lithium metal batteries being even more problematic when there is no excess lithium in the cell.

296 Problematic with class modeling is determining which one

297 f nucleic acid targets at low copy number is problematic with the limit of detection at 95 percent co

298 Klebsiella pneumoniae (CR-Kp) are especially problematic, with a 50 % average survival rate.

299 itation following hemorrhagic shock is often problematic, with development of prolonged hypotension a

300 y of morphologically cryptic lineages can be problematic, yet may be crucial to understanding ecologi