ライフサイエンスコーパス: prodigiosin

1 ate) and a linear tripyrrole red antibiotic, prodigiosin.

2 sin ShlA and the biologically active pigment prodigiosin.

3 39006 produces the red-pigmented antibiotic prodigiosin.

4 -2-em-3-carboxylic acid and the red pigment, prodigiosin.

5 lved in the biosynthesis of the red pigment, prodigiosin.

6 n that produces a vibrant red pigment called prodigiosin.

7 es a greater than fivefold overproduction of prodigiosin.

8 first total synthesis of 2-(p-hydroxybenzyl)-prodigiosins (2-5), isoheptylprodigiosin (6), and geomet

9 S. marcescens expresses prodigiosin, a bright red and cell-associated pigment wh

10 Prodigiosin, a microbial pigment, was produced using Ser

11 In exhibiting this capability, prodigiosin and its analogue provide lead compounds to r

12 Prodigiosin and its structural analogue (compound R) ind

13 ) /Cl(-) symport activity similar to that of prodigiosin and most importantly demonstrates unpreceden

14 f mutant p53/p73 interaction was specific to prodigiosin and not related to mTOR inhibition.

15 Purified prodigiosin and ShlA from Escherichia coli further suppo

16 ugs [A bacteria-synthesized anticancer drug (prodigiosin) and paclitaxel] using single solvent evapor

17 gulation of GV formation, flotation, and the prodigiosin antibiotic, and downregulation of flagellar

18 g production of gas vesicles, carbapenem and prodigiosin antibiotics, and infection in Caenorhabditis

19 Production of gas vesicles, carbapenem and prodigiosin antibiotics, and motility are controlled by

20 Other possible functions for prodigiosin as a mediator of cell death at population st

21 -mediated cell death and reacts by producing prodigiosin as a stress response.

22 A positive control of transcriptional of the prodigiosin-associated pig operon by directly binding to

23 Finally, we describe a new prodigiosin-based bioassay for detection of some N-acyl

24 xpression of the pig cluster responsible for prodigiosin biosynthesis in two Serratia sp. In this art

25 Regulation of prodigiosin biosynthesis involves a complex hierarchy, w

26 ating, for the first time, that the complete prodigiosin biosynthetic gene cluster had been cloned an

27 Mutations in pigS reduced production of prodigiosin by decreasing the transcription of the biosy

28 here a kinetic model relating cell, ATP, and prodigiosin concentration changes for S. marcescens duri

29 e accompanied by large decreases in cellular prodigiosin concentration; low growth rates were associa

30 anomalous release kinetics of a cancer drug (prodigiosin) frompoly-n-isopropyl-acrylamide (P(NIPA))-b

31 Prodigiosin has implications in virulence of S. marcesce

32 er suggesting a negative regulatory role for prodigiosin in cell and energy production under aerobic

33 ll materials (5 % w/v) in water, mixing with prodigiosin in ethanol (1:1), and adding Tween 80 as an

34 phage treatments, and (ii) overproduction of prodigiosin in response to phage could be exploited for

35 Taking cues from previous studies on prodigiosin, including possible proapoptotic anticancer

36 Moreover, prodigiosin increased levels of the transcription factor

37 Mechanistic studies revealed that prodigiosin increased the levels of p73 and reduced leve

38 Consistently, prodigiosin induced activation of a p53-responsive lucif

39 Prodigiosin induced the expression of p73 and disrupted

40 [Aldefluor(+)] CRCSCs in vitro Furthermore, prodigiosin inhibited the growth of xenograft tumors ini

41 Prodigiosin is one of the most potent anion transporters

42 kdown or DeltaNp73 overexpression suppressed prodigiosin-mediated inhibition of colonosphere formatio

43 c-Jun knockdown attenuated prodigiosin-mediated p53-reporter activation, DeltaNp73

44 ical activity is distinct from other related prodigiosin natural and unnatural products and is even m

45 PigS-mediated control of prodigiosin occurred via binding directly to a short inv

46 Injections of LHRH-conjugated drugs (LHRH-prodigiosin or LHRH-paclitaxel) into groups of 4-week-ol

47 ts of an experimental study of cancer drugs (prodigiosin or paclitaxel) conjugated to Luteinizing Hor

48 Prodigiosin (PG) emerges from this study as a potent TGF

49 Prodigiosin (PG) is a naturally occurring polypyrrole re

50 squid pen powder (SPP)-containing medium on prodigiosin (PG) production by Serratia marcescens TKU01

51 we demonstrate a unique antiviral effect of prodigiosin (PG), a natural secondary metabolite produce

52 inizing Hormone-Releasing Hormone conjugated prodigiosin (PG-LHRH)] for the treatment and possible pr

53 ween LHRH molecular recognition units on the prodigiosin (PGS) and paclitaxel (PTX) drugs and overexp

54 zes several secondary metabolites, including prodigiosin (Pig) and a carbapenem antibiotic (Car).

55 The strain ATCC39006 makes the red pigment, prodigiosin (Pig), and the beta-lactam antibiotic carbap

56 3-carboxylic acid (Car) and the red pigment, prodigiosin (Pig).

57 beta-lactam) and a red pigmented antibiotic, prodigiosin (Pig; a tripyrrole), which are controlled by

58 ndary metabolites, carbapenem antibiotic and prodigiosin pigment, is under pheromone-mediated transcr

59 3 activation, on CRCSCs in vitro and in vivo Prodigiosin prevented colonosphere formation independent

60 tic pathway of the red-pigmented antibiotic, prodigiosin, produced by Serratia sp. is known to involv

61 Serratia marcescens is a red pigment (prodigiosin)-producing Gram-negative bacillus that is na

62 onal regulator of multiple genes involved in prodigiosin production.

63 etermined their importance in the control of prodigiosin production.

64 P) was shown to be equivalent to the rate of prodigiosin production.

65 (PKSs) found in the biosynthetic pathways of prodigiosin, pyoluteorin, mycosubtilin, nikkomycin, ente

66 e natural products, metacycloprodigiosin and prodigiosin R1.

67 f the literature, these results suggest that prodigiosin reduces ATP production by a process termed e

68 Prodigiosin restored p53 signaling in cancer cells harbo

69 e most effective wall material for improving prodigiosin stability and controlled release for food, p

70 re we named psrA, that positively controlled prodigiosin synthesis in S. marcescens.

71 However, compared to the natural product prodigiosin, synthetic anion transporters have low-to-mo

72 this study, we report the identification of prodigiosin that can reactivate p53 family-dependent tra

73 Prodigiosin was induced most strongly during limited gro

74 Purified prodigiosin was obtained from stationary phase bacteria

75 vestigated the effects of the small-molecule prodigiosin, which restores the p53 pathway in tumor cel