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1 ne regulation (eukaryotes) and host defense (prokaryotes).
2 en obtained via lateral gene transfer from a prokaryote.
3 se of sTeLIC, a pLGIC from another symbiotic prokaryote.
4 SPR-Cas systems provide acquired immunity in prokaryotes.
5 ukaryote world but has never been applied to prokaryotes.
6 ery little is known about membrane fusion in prokaryotes.
7 ionarily and ecologically important group of prokaryotes.
8 served presence and role in many and diverse prokaryotes.
9 amily, is the major Mg(2+)-influx pathway in prokaryotes.
10 immunity against selfish genetic elements in prokaryotes.
11 purposing for genome editing applications in prokaryotes.
12 nserved in eukaryotes and also found in some prokaryotes.
13 Oomycetes, but neither other eukaryotes nor prokaryotes.
14 and providing insight into the evolution of prokaryotes.
15 ity against mobile genetic elements (MGE) in prokaryotes.
16 ributed in eukaryotes but are not present in prokaryotes.
17 widely studied of all extremely acidophilic prokaryotes.
18 tion against invading phages and plasmids in prokaryotes.
19 tabolites synthesised by both eukaryotes and prokaryotes.
20 and genetic variation in both eukaryotes and prokaryotes.
21 lyze membrane transport of micronutrients in prokaryotes.
22 tes, including fungi, and, more recently, in prokaryotes.
23 e modules that are ubiquitous in free-living prokaryotes.
24 re thought to have originated as free-living prokaryotes.
25 tems preponderantly present in multicellular prokaryotes.
26 nt protein remodeling in both eukaryotes and prokaryotes.
27 eading to a disperse distribution pattern in prokaryotes.
28 tial human micronutrient made exclusively by prokaryotes.
29 eukaryotic cells evolved from endosymbiotic prokaryotes.
30 omic patterns of cis-regulatory evolution in prokaryotes.
31 m and could therefore be a common feature in prokaryotes.
32 covery of homologues of tubulin and actin in prokaryotes.
33 tured representative deep-sea methanotrophic prokaryotes.
34 e present in diverse cells of eukaryotes and prokaryotes.
35 ected glycerophospholipids in eukaryotes and prokaryotes.
36 nder polygenic lineage-specific selection in prokaryotes.
37 are no more bioenergetically efficient than prokaryotes.
38 widely used for orthology identification in prokaryotes.
39 ish an RNA-based adaptive immunity system in prokaryotes.
40 kable dynamic filaments nearly ubiquitous in prokaryotes.
41 thesis of adenosylcobalamin (AdoCbl) in many prokaryotes.
42 ever, such a mechanism remains unexplored in prokaryotes.
43 des a barrier to horizontal gene transfer in prokaryotes.
44 n into bioavailable ammonium in diazotrophic prokaryotes.
45 y microalgae acquire vitamin B12 from marine prokaryotes.
46 ing our knowledge across the whole domain of prokaryotes.
47 ve and inducible promoters in eukaryotes and prokaryotes.
48 the first documentation of this activity in prokaryotes.
49 nd fungi, but remain largely unidentified in prokaryotes.
50 mins as it is biosynthesized only by certain prokaryotes.
51 immunity against mobile genetic elements in prokaryotes.
52 t of how genetic information is organized in prokaryotes.
53 ons from organisms other than green algae or prokaryotes.
54 eflects the polycistronic arginine operon in prokaryotes.
55 most abundant toxin/antitoxin (TA) system in prokaryotes.
56 programmable gene editing in eukaryotes and prokaryotes.
57 ated Decay-like quality-control mechanism in prokaryotes.
58 sporters mediate import of micronutrients in prokaryotes.
59 that control the transcription initiation in prokaryotes.
60 204,938 nonredundant genomes from 4,644 gut prokaryotes.
61 ine genome-specific regulatory mechanisms in prokaryotes.
62 R array, establishing nucleic acid memory in prokaryotes.
63 igher organisms, single cell eukaryotes, and prokaryotes.
64 rRNAs are nearly twice as large as those of prokaryotes.
65 al system of self/non-self discrimination in prokaryotes [1], which protects hosts from exogenous DNA
67 d an analogous elemental milieu and harbored prokaryotes affiliated with fifty-nine phyla, among whic
72 PR) system, an immune system analog found in prokaryotes, allows a single-guide RNA to direct a CRISP
74 that bifurcates to favor direct tunneling in prokaryotes and a two-step hopping mechanism in eukaryot
76 there is a long-standing effort to search in prokaryotes and eukarya for proteins promoting HJ migrat
77 osed as part of defense systems that protect prokaryotes and eukaryotes against the proliferation of
78 llular aging as a general process, affecting prokaryotes and eukaryotes alike and according to simila
80 n evolutionarily conserved mechanism used by prokaryotes and eukaryotes alike to control cell fate an
83 from 9282 complete genome chromosomes of all prokaryotes and eukaryotes available at NCBI, we observe
84 th quorum sensing and 'community effects' in prokaryotes and eukaryotes can be drawn, arguing that a
85 mming from the earliest interactions between prokaryotes and eukaryotes have evolved to mediate micro
86 is a widespread lipophilic molecule in both prokaryotes and eukaryotes in which it primarily acts as
88 GyrI-like proteins are widely distributed in prokaryotes and eukaryotes, and recognized as small-mole
90 GABA) serves diverse biological functions in prokaryotes and eukaryotes, including neurotransmission
92 proteins that store copper in the cytosol of prokaryotes and eukaryotes, where this reactivity is als
105 common type of transcriptional regulators in prokaryotes and function by altering gene expression in
106 its metabolic capabilities uncharacterized, prokaryotes and fungi have the potential to act as mutua
108 he Fluc family of F(-) ion channels protects prokaryotes and lower eukaryotes from the toxicity of en
109 ystems are relevant protein machineries from prokaryotes and lower eukaryotes that enable cells to se
111 protein transport (Tat pathway) is found in prokaryotes and plant organelles and transports folded p
112 e metabolic networks have been used to study prokaryotes and protists and have proven valuable in ide
113 other HPP superfamilies known previously in prokaryotes and resembles myo-inositol monophosphatases
115 that is exclusive to oxygenic photosynthetic prokaryotes and that is based on the primary sequence th
116 d our understanding of the interplay between prokaryotes and their environment, and CRISPR-based mole
118 thologs have been found and characterized in prokaryotes and they display highly similar structure-fu
121 Filamentous inoviruses are pervasive across prokaryotes, and in particular, several Gram-negative ba
122 SSRs are found in eukaryotes as well as prokaryotes, and length variation in them occurs at freq
123 sequencing depth for RIBO-Seq experiments in prokaryotes, and studies vary significantly in total rea
124 re found ubiquitously in both eukaryotes and prokaryotes, and they comprise the largest of all of the
125 ersity and ubiquity of microbes (eukaryotes, prokaryotes, and viruses) associated with larger 'host'
127 sed to reveal genome replication dynamics in prokaryotes, archaea and a wide range of eukaryotes, inc
130 d, short palindromic repeat (CRISPR) loci in prokaryotes are composed of 30-40-base-pair repeats sepa
131 wo studies show that the DNA-free regions in prokaryotes are full of large biomolecules, which exclud
132 e terrestrial or aquatic environments, where prokaryotes are prevalent, the tropical airborne biomass
135 r identification of essential genes (EGs) in prokaryotes are usually expensive, time-consuming and so
137 Cyanobacteria, a group of photosynthetic prokaryotes, are attractive hosts for biotechnological a
138 Here, we show that fumarase of the model prokaryote Bacillus subtilis (Fum-bc) is induced upon DN
140 Cyanobacteria and eukaryotic microalgae) and prokaryotes (bacteria and archaea), 2 microbial groups t
141 fter a month of operation, the most-abundant prokaryote belonged to an uncharacterized clade of Chlor
142 lity of a wide range of organisms (including prokaryotes) beyond the reach of optoacoustic tools.
143 ne-regulatory mechanisms probably evolved in prokaryotes billions of years before the emergence of mo
146 are synthesized de novo by only a subset of prokaryotes, but some organisms encode partial biosynthe
147 espiratory electron transport system of some prokaryotes by shuttling electrons between membrane-boun
153 ltiple antiviral defense mechanisms found in prokaryotes, CRISPR-Cas systems stand out as the only kn
155 or alien organisms in nature, eukaryotes and prokaryotes developed various communication systems to c
157 advance our understanding of the strategies prokaryotes employ to regulate cellular processes relate
159 ors, and solved co-crystal structures of the prokaryote (Erwinia) channel ELIC bound either to a posi
160 sfer (HGT) is widespread in the evolution of prokaryotes, especially those associated with the human
162 a bacterial small RNA-mediated mechanism for prokaryote-eukaryote interaction and may pave the way fo
166 aryotes from the bioenergetic constraints on prokaryotes, facilitating the evolution of morphological
167 al primary step of the CRISPR-Cas pathway in prokaryotes for developing host immunity to mobile genet
169 oss of defense genes during the evolution of prokaryotes; formation of genomic defense islands; evolu
171 mic forms of life-5-methylcytosine separates prokaryotes from eukaryotes and 5-hydroxymethylcytosine
175 , previously studied pAgos from thermophilic prokaryotes function at elevated temperatures, which lim
178 s is explained in part by relatively compact prokaryote genomes that facilitate assembly and gene pre
180 stems(1-13), the application of scRNA-seq to prokaryotes has been hindered by their extremely low mRN
183 imal and plant P4Hs target peptidyl proline, prokaryotes have been known to use free l-proline as a p
185 tors are key transcriptional regulators that prokaryotes have evolved to respond to environmental cha
187 er chromatids during mitosis, eukaryotes and prokaryotes have structural maintenance of chromosome (S
190 ds, which are well-studied drivers of HGT in prokaryotes, have been reported previously in red algae
191 Almost all organisms, from eukaryotes to prokaryotes, have evolved enzymes to make and break thes
192 f acetylcholine receptors, ion channels from prokaryote homologs-Erwinia chrysanthemi ligand-gated io
193 s cost for the hosts; therefore, at least in prokaryotes, horizontal mobility of defence systems, med
195 DUF328 family proteins are present in many prokaryotes; however, their molecular activities are unk
196 The International Code of Nomenclature of Prokaryotes (ICNP) only recognizes cultures as 'type mat
197 of both chemolithotrophic and heterotrophic prokaryotes in an unusual ecosystem isolated from the su
198 ish the distinctive roles played by abundant prokaryotes in cobalamin-based microbial interdependenci
199 le for cyanobacteria, which lag behind other prokaryotes in synthetic biology despite their huge pote
201 similar to multicellular life, the traits of prokaryotes in their natural habitats are constrained by
203 een oxygen sensing and chemotaxis in diverse prokaryotes, including anaerobes of ancient origin.
205 ogues from humans, Trichoplax adhaerens, and prokaryotes, informing on differences in mobile elements
206 ial effects atrazine maybe having on mollusk-prokaryote interactions, we used 16S rRNA gene amplicons
209 d sequentially, suggesting that evolution in prokaryotes is governed by functional assembly patterns.
210 n eukaryotic organelles and their progenitor prokaryotes is regulated by a series of proteases includ
212 erax volcanii is, to our knowledge, the only prokaryote known to tolerate CRISPR-Cas-mediated damage
213 OP via an ATP-dependent 5-oxoprolinase; most prokaryotes lack homologs of this enzyme (and the gamma-
215 m, Local Distribution of Short Sequences for Prokaryotes (LDSS-P), to identify conserved short motifs
216 evidence suggested that actinonin inhibited prokaryote-like post-translational modification in the a
217 ions between NusG/Spt5 and RNA polymerase in prokaryotes, little is known about how the binding of eu
221 used in the presence of carotenoid esters in prokaryote microalgae, an event that has not been shown
222 tent and respiratory shield in other aerobic prokaryotes might be similar to those of E. coli and mit
225 ty against invasive mobile genetic elements, prokaryotes must first integrate fragments of foreign DN
227 ablished member of the higher eukaryotes and prokaryotes nucleotide-binding (HEPN) domain-containing
228 ty provided by the two Higher Eukaryotes and Prokaryotes Nucleotide-binding (HEPN) domains, is requir
237 uinone is a prominent redox cofactor in many prokaryotes, produced from a ribosomally synthesized and
238 s, function as an adaptive immune system for prokaryotes, protecting them against foreign invaders.
240 ant post-translational modification (PTM) in prokaryotes, regulates various microbial metabolic pathw
242 ate, only form of adaptive immunity found in prokaryotes, represents a flexible mechanism to recall p
243 ause rRNA constitutes the majority of RNA in prokaryotes, represents recently active organisms, and y
244 Understanding how the metabolic rates of prokaryotes respond to temperature is fundamental to our
249 lso proteins of unknown function, resembling prokaryote single-domain, voltage-gated Na(+) channels (
250 , bacteria have the ability to biosynthesize prokaryote-specific NulOs, of which there are several kn
252 s become limiting, we tested the efficacy of prokaryote-specific tRNA synthetase inhibitors, indolmyc
254 g has customarily been more widely used with prokaryotes than eukaryotes, because the method is thoug
256 l advances in genetic/genomic engineering of prokaryotes that have enabled upgrading of the utilities
257 share a close phylogenetic relationship with prokaryotes that live in similar habitats as the Cyanidi
259 mentous nanomachines virtually ubiquitous in prokaryotes that mediate a wide variety of functions.
260 ctionally versatile filaments, widespread in prokaryotes, that belong to a large class of filamentous
261 his temperature is central to the study of a prokaryote, the thermal stability and temperature depend
262 In contrast to the DNA-based viruses in prokaryotes, the emergence of eukaryotes provided the ne
264 mechanism affecting genome rearrangements in prokaryotes, the symmetrical inversions around the origi
267 ISPR-Cas adaptive immune systems are used by prokaryotes to defend against invaders like viruses and
268 egulates a myriad of cellular processes from prokaryotes to eukaryotes and has important implications
269 a direct, causal role in the transition from prokaryotes to eukaryotes and the subsequent explosive d
270 rminal domain (C-Ala) that is conserved from prokaryotes to humans but with a wide sequence divergenc
273 ental change in J-protein biology during the prokaryote-to-eukaryote transition allows for increased
275 ogether, all these findings indicate that in prokaryotes, translation start signals are subject to we
277 identity-defining step in PI biosynthesis in prokaryotes, unique to mycobacteria and few other bacter
279 e evolutionary impact of such constraints in prokaryotes, using probabilistic ancestral reconstructio
281 organisms and are synthesized by a subset of prokaryotes via distinct aerobic and anaerobic routes.
282 nts has bombarded nuclei since the ancestral prokaryotes were engulfed by a precursor of the nucleate
285 en a powerful tool for uncovering biology in prokaryotes, where whole-genome saturating screens have
286 nique glycosidic linkages, particularly from prokaryotes, which are resistant to enzymatic or chemica
287 t little is known of its influence on marine prokaryotes, which represent the largest living biomass
288 ong-standing importance of the Psp system in prokaryotes, while inter- and intra-phyla variations wit
289 ke up RNA-guided, adaptive immune systems in prokaryotes whose effector proteins have become powerful
290 comprise diverse adaptive immune systems in prokaryotes whose RNA-directed nucleases have been co-op
293 CRISPR-Cas adaptive immune systems provide prokaryotes with defense against viruses by degradation
294 ers to genomically circumscribe any group of prokaryotes with measurable DNA similarity and that uses
296 l code exist, particularly in organelles and prokaryotes with small genomes, they are limited in scop
297 annotation, facilitating the study of those prokaryotes without experimentally derived gene essentia
299 The corrinoid B(12) is synthesized only by prokaryotes yet is widely required by eukaryotes as an e
300 al to the development of both eukaryotes and prokaryotes, yet the mechanisms behind its formation are