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1 NA(Ala) by escaping from the intrinsic AlaRS proofreading activity.
2 ations, was effectively masked by nsp14-ExoN proofreading activity.
3 sion is improved to about [1/10(7)] by their proofreading activity.
4 g play important roles in controlling Pol II proofreading activity.
5 ain, a finding consistent with PolA1 lacking proofreading activity.
6 isplay a certain level of resistance to this proofreading activity.
7 letely block export, indicating an effective proofreading activity.
8 A polymerase III possesses 3'-exonucleolytic proofreading activity.
9 nucleotides by polymerase alpha, which lacks proofreading activity.
10 ly with pol beta, a polymerase lacking 3'-5' proofreading activity.
11 y, but it is error prone because it bears no proofreading activity.
12 is based on Pfu polymerase mix, which has a proofreading activity.
13 merases with high nucleotide selectivity and proofreading activity.
14 The yeast Pol(eta) lacked a nuclease or a proofreading activity.
15 erevisiae that possess 3' --> 5' exonuclease proofreading activity.
16 d is lost in the absence of DNA polymerase y proofreading activity.
17 g the pol3-01 mutation defective in Poldelta proofreading activity.
18 integration of RNA polymerase, capping, and proofreading activities.
19 nd as a consequence in different patterns of proofreading activities.
20 unlike in other aaRSs, this does not affect proofreading activity against the noncognate substrates
21 s characteristic low fidelity and absence of proofreading activity allow FMDV to rapidly mutate and a
22 site or a thymine-thymine dimer); a greater proofreading activity; an increased exonuclease/polymera
23 T) does not possess 3'- to 5'-exonucleolytic proofreading activity and because RT has been shown to b
24 mutations derive from defects in Polepsilon proofreading activity and not from the role of Polepsilo
25 by DNA polymerase-associated exonucleolytic proofreading activity and/or the postreplicative mismatc
26 on of DNA polymerase nucleotide selectivity, proofreading activity, and DNA mismatch repair (MMR).
28 DNA polymerase III epsilon subunit, and the proofreading activities associated with T4, varphi29, an
29 tases prevent mistranslation by relying upon proofreading activities at multiple stages of the aminoa
31 polymerase devoid of 3'-5' exonuclease, or "proofreading", activity blended with a small amount of a
32 enesis is to use a DNA polymerase that lacks proofreading activity but contributes to DNA replication
33 ion in DNA polymerase delta that reduces its proofreading activity but is not a mutator in the hetero
34 mutations result from defects in Polepsilon proofreading activity by analyzing their rate in Polepsi
35 otein synthesis machinery lacks the tyrosine proofreading activity characteristic of cytosolic transl
36 ification of primers and DNA polymerase with proofreading activity completely eliminated mismatch amp
37 al domain of Pol3, containing polymerase and proofreading activities, could be effectively replaced b
39 icative DNA polymerases present an intrinsic proofreading activity during which the DNA primer chain
40 -L82E/L82'E variant is predicted to maintain proofreading activity, exhibiting a similar reaction bar
41 uggests a possible role in BER for Ape1 as a proofreading activity for the relatively inaccurate DNA
45 rt the inefficiency of the exonuclease as a "proofreading" activity for m6G, since virtually all muta
51 repeats were destabilized, showing that the proofreading activity is essential for maintaining the i
52 yme DNA polymerase I Klenow fragment lacking proofreading activity, Kf (exo-), than deoxythymidine gl
53 has revealed that polymerases with intrinsic proofreading activity may cooperate with non-proofreadin
54 mutagenesis resulting from loss of Poldelta proofreading activity may in part be explained by enhanc
56 In addition, altering the processivity or proofreading activity of DNA polymerase delta shortened
58 early all mismatch correction depends on the proofreading activity of DNA polymerase-delta, although
61 corporated nucleotides that have escaped the proofreading activity of DNA polymerases, recognizing no
65 ds normally excluded from translation by the proofreading activity of phenylalanyl-tRNA synthetase (P
70 erichia coli and hs mt LeuRS reveal that the proofreading activity of the mt enzyme is disrupted by t
71 NA viral polymerases; and that for CoVs, the proofreading activity of the nsp14-ExoN is epistatic to
72 taumuDC) strains if the 3' to 5' exonuclease proofreading activity of the Pol III epsilon subunit was
73 of the Umu proteins if the 3'-5' exonuclease proofreading activity of the pol III epsilon-subunit als
77 yl-tRNA synthetase gene that compromises the proofreading activity of this enzyme during aminoacylati
79 in the center for editing that diminish the proofreading activity of valyl-tRNA synthetase (ValRS).
81 a nuclease activity, which differs from the proofreading activity often associated with DNA polymera
84 rom the polymerase's intrinsic catalytic and proofreading activities, processivity is typically attri
85 NA polymerase activity was unaffected, while proofreading activity ranged from 60% of the wild-type l
86 they use both a processivity factor and have proofreading activity reminiscent of DNA organisms in ad
87 found that this RNAP has very high intrinsic proofreading activity, resulting in nearly as low a leve
89 nuclease activity and severely decreased the proofreading activity than the wild-type, the bypass eff
90 xpressed (T1) and another (T2) with impaired proofreading activity that also generates mischarged Ser
91 despite having an associated 3'-exonuclease proofreading activity that preferentially degrades AT-ri
92 r, in vitro and ex vivo analyses reveal that proofreading activity to hydrolyze Tyr-tRNA(Phe) is incr
93 mutation that is defective in signal peptide proofreading activity were employed to distinguish betwe
94 that harbor or lack 3' --> 5'-exonucleolytic proofreading activity were purified from Escherichia col
95 moves the 3'-slipped hairpin using its 3'-5' proofreading activity when the hairpin contains no immed
96 hysiologically significant, and furthermore, proofreading activity with an RNA template was also obse
97 am+ Pol C, which contains the polymerase and proofreading activities within the same polypeptide chai