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1 ly to be important for optimizing functional protein biosynthesis.
2 olved in gametogenesis while down-regulating protein biosynthesis.
3 ment, cell invasion, antigenic variation and protein biosynthesis.
4 oacyl-tRNAs (aa-tRNAs) onto the ribosome for protein biosynthesis.
5 the main target for antibiotics that inhibit protein biosynthesis.
6 at is dependent on TNF signaling and de novo protein biosynthesis.
7 ntegration at the translocon during membrane protein biosynthesis.
8 t dissociate into subunits in order to begin protein biosynthesis.
9 havior of incomplete chains generated during protein biosynthesis.
10 eins, and enzymes involved in amino acid and protein biosynthesis.
11 nce of molecular chaperones participating in protein biosynthesis.
12 lised by the cell to optimise the outcome of protein biosynthesis.
13 into cellular responses to impaired plastid protein biosynthesis.
14 ting can modulate mRNA function and rates of protein biosynthesis.
15 l hemoglobin, far more than they require for protein biosynthesis.
16 mechanisms to ensure quality control during protein biosynthesis.
17 he other route to this essential compound in protein biosynthesis.
18 has been shown to block translocation during protein biosynthesis.
19 in the ribosome is a fundamental step during protein biosynthesis.
20 st suggests that organisms minimize costs of protein biosynthesis.
21 cyl groups mimic a chemistry found in modern protein biosynthesis.
22 RF through which DENR acts to regulate CLOCK protein biosynthesis.
23 ll cycle progression and on nucleic acid and protein biosynthesis.
24 lidinones are potent inhibitors of bacterial protein biosynthesis.
25 lationship between amino-acid metabolism and protein biosynthesis.
26 ons with mRNA, tRNA and other ligands during protein biosynthesis.
27 ptidyl-tRNA hydrolysis during termination of protein biosynthesis.
28 llular accumulation of DOX and inhibition of protein biosynthesis.
29 onment during 2 h of inhibition of host cell protein biosynthesis.
30 genes proposed to be involved in iron-sulfur protein biosynthesis.
31 d suggest a role for ubiquitination early in protein biosynthesis.
32 receptor chimaera in the absence of de novo protein biosynthesis.
33 ource of GTP for translational elongation in protein biosynthesis.
34 ognate amino acid and provide substrates for protein biosynthesis.
35 thways related to mitochondrial function and protein biosynthesis.
36 ve understanding of productive and erroneous protein biosynthesis.
37 and organoids, NLE1 was limiting for de novo protein biosynthesis.
38 airing nucleolar protein quality control and protein biosynthesis.
39 binding to the ribosome and interfering with protein biosynthesis.
40 ns but are typically not incorporated during protein biosynthesis.
41 govern ribosome biogenesis and to fine-tune protein biosynthesis.
42 Ribosomes are the workplace for protein biosynthesis.
43 t into its functioning during suppression of protein biosynthesis.
44 changed cell geometry or upon inhibition of protein biosynthesis.
45 at must be resolved to explain the origin of protein biosynthesis.
46 ting conserved molecular mechanisms, such as protein biosynthesis.
47 slation elongation is a crucial phase during protein biosynthesis.
48 d genetic code with up to 256 new codons for protein biosynthesis.
49 ant life employs the same 20 amino acids for protein biosynthesis.
50 metabolism and cell wall, nucleic acid, and protein biosynthesis.
51 may selectively and differentially modulate protein biosynthesis.
52 for efficient translation initiation during protein biosynthesis.
53 ion of proteins involved in cytoskeleton and protein biosynthesis.
54 ty of the TFEB protein and altered lysosomal protein biosynthesis.
55 al subunits, and reduced activity of plastid protein biosynthesis.
56 here they served as precursors for bacterial protein biosynthesis.
57 conserved process for secretory and membrane protein biosynthesis.
58 and the second, more potent as inhibitors of protein biosynthesis.
59 otein S6 was also modulated by inhibition of protein biosynthesis.
60 eIF3 plays a key role in protein biosynthesis.
61 so activated by reduction in the accuracy of protein biosynthesis.
62 the E1 molecule and then utilize tyrosine in protein biosynthesis.
63 r a spring between these two proteins during protein biosynthesis.
64 ative activity, and amino acid transport and protein biosynthesis.
65 nsensitive to cycloheximide, an inhibitor of protein biosynthesis.
66 some of which encode proteins that modulate protein biosynthesis.
67 0 inhibition because of their high amount of protein biosynthesis.
68 ly linked to ribosomes and are implicated in protein biosynthesis.
69 lterations delimit the cellular capacity for protein biosynthesis, accelerate growth and drive diseas
72 that post-translational modifications during protein biosynthesis along secretory pathways play criti
73 ddition to their essential catalytic role in protein biosynthesis, aminoacyl-tRNA synthetases partici
75 by upregulation of enzymes involved in both protein biosynthesis and biosynthetic pathways, as well
78 gh its highly context-specific regulation of protein biosynthesis and classifies PLAG1 among a rare s
79 amino acids are the basic building blocks of protein biosynthesis and contribute to many other metabo
80 ng quality control processes associated with protein biosynthesis and cotranslational folding (CTF).
83 is maintained and regulated by the rates of protein biosynthesis and degradation in living systems.
84 olved in signal transduction, transcription, protein biosynthesis and degradation, and cell motility,
86 assessed by measuring adhesive strength, and protein biosynthesis and deposition were determined by i
88 ks-1/S6 kinase or in ife-2/eIF4E also reduce protein biosynthesis and extend lifespan, but only rsks-
92 onine (HHT) is a first-in-class inhibitor of protein biosynthesis and is FDA-approved for the treatme
96 ncentrate iron in iron-oxy minerals for iron-protein biosynthesis and protection against oxy radical
97 egulation of genes involved in all stages of protein biosynthesis and ribosome biogenesis during both
99 nificant over-representation of genes in the protein biosynthesis and stress response categories.
100 he roles of tRNA(Glu) at the intersection of protein biosynthesis and tetrapyrrole biosynthesis.
101 o the Kozak consensus sequence for mammalian protein biosynthesis and the 3'-UTR demonstrated three c
102 fficient mRNA splicing is a prerequisite for protein biosynthesis and the eukaryotic splicing machine
103 thesis of aromatic amino acids essential for protein biosynthesis and the production of a wide array
105 ted functions were over-represented in loopy proteins, biosynthesis and energy metabolism were under-
106 g the kinases PIM2 and DYRK3, which regulate protein biosynthesis, and a number of genes in cilium bi
109 ntral metabolism, including gluconeogenesis, protein biosynthesis, and purine/pyrimidine synthesis wa
112 he UPR activation, and attenuation of myelin protein biosynthesis; and resulted in late-onset, progre
113 ve effect of CHES1, indicating that PIM2 and protein biosynthesis are important targets of the antipr
114 ses like DNA replication, RNA synthesis, and protein biosynthesis are located inside the "cytoplasm"
115 e proteins (SvsR) is presumed to function in protein biosynthesis, because it exhibits a high degree
116 bit bacterial growth and cell-free ribosomal protein biosynthesis but also harbors an orthogonal func
117 t affected by cycloheximide, an inhibitor of protein biosynthesis, but is affected by proteasome inhi
119 icrobial peptides (PrAMPs) inhibit bacterial protein biosynthesis by binding to the polypeptide exit
120 he A-tRNA entrance corridor, thus inhibiting protein biosynthesis by blocking the binding site of the
121 minoacyl-tRNA synthetases play a key role in protein biosynthesis by catalyzing the specific aminoacy
122 y activates GADD34, which promotes ER client protein biosynthesis by dephosphorylating phospho-Ser 51
123 ropose that oxazolidinones inhibit bacterial protein biosynthesis by interfering with the binding of
124 transport particle, and may control storage protein biosynthesis by regulating one or more processes
126 ossibility that small molecules can regulate protein biosynthesis by selectively binding to mRNA.
127 These findings suggest that inhibition of protein biosynthesis can alter degradation of some prote
129 and cellular growth, indicating that reduced protein biosynthesis can confer a suppressive effect on
131 ism, ion homeostasis, gene transcription and protein biosynthesis, compatible solute production, horm
132 on of Cox2 levels, a proxy for mitochondrial protein biosynthesis, coupled with the accumulation of t
135 dulin), we outline the general principles of protein biosynthesis, delineate the recognition and degr
136 ipts proved time-, dose-, nitric oxide-, and protein biosynthesis-dependent but glucose independent.
137 e the first committed step in O-glycosylated protein biosynthesis, determine sites of O-glycosylation
138 ghly significant number of genes involved in protein biosynthesis displayed an increase in transcript
139 critical transitions in progression include protein biosynthesis, E26 transformation-specific (ETS)
141 n separate submaps, with pathways related to protein biosynthesis, endoplasmic reticulum retention, e
142 tics to identify genes co-occurring with the protein biosynthesis enzyme SepCysS, which converts phos
143 idant defense enzymes, molecular chaperones, protein biosynthesis enzymes, and trafficking and degrad
144 th conditions of mammalian mRNAs that encode protein biosynthesis factors and contain hallmark 5'-ter
146 for physiological disorders associated with protein biosynthesis, folding, trafficking, and membrane
147 work of molecular interactions that balances protein biosynthesis, folding, translocation, assembly/d
148 romolecular assembly that is responsible for protein biosynthesis following genetic instructions in a
149 nE gene, which has been reported to uncouple protein biosynthesis from tetrapyrrole biosynthesis in c
150 lta strains and that the stress response and protein biosynthesis gene categories were coordinately r
151 lthough correct tRNA 3' ends are crucial for protein biosynthesis, generation of mature tRNA 3' ends
154 1, lamin B1, vimentin, and beta-actin) or in protein biosynthesis (glutamyl-prolyl-transfer RNA synth
155 ion in one or more of the steps that control protein biosynthesis has been associated with alteration
156 ing the process of molecular translation, or protein biosynthesis, has emerged as a major opportunity
158 lation system execute gene transcription and protein biosynthesis in a timely and programmable fashio
159 ity of large cells to scale nucleic acid and protein biosynthesis in accordance with cell volume incr
161 esis in the panicle of adult plants, whereas protein biosynthesis in adult leaves was 8-fold lower th
162 somes, the essential organelles required for protein biosynthesis in all cells, cause tissue-specific
163 Despite the broad requirement of GlyRS for protein biosynthesis in all cells, mutations in this gen
170 expression elicits a sustained repression of protein biosynthesis in cells responding to stress.
172 cific RNA structures that regulate ribosomal protein biosynthesis in E. coli are narrowly distributed
173 r, these studies have shown that acute phase protein biosynthesis in enterocytes is regulated by infl
175 Inhibition was observed without effects on protein biosynthesis in general or PrP-sen biosynthesis
176 inactivation reversed attenuation of myelin protein biosynthesis in oligodendrocytes and restored my
177 e study of interactions between DNA, RNA and protein biosynthesis in order to develop a more comprehe
180 defense system in the plant kingdom, wherein protein biosynthesis in short, procumbent glandular tric
181 folded or surplus proteins or by-products of protein biosynthesis in the ER and delivers them to 26S
182 ependent increase in myocardial TNF mRNA and protein biosynthesis in the heart as well as in cultured
184 hanism mediated by ERs, and de novo mRNA and protein biosynthesis, in a sex- and region-dependent man
185 gth, taken as models for different stages of protein biosynthesis, in the absence and presence of the
186 air one or more steps of tRNA maturation and protein biosynthesis including 5'-end-processing, post-t
187 n the Sec translocon and its role in nascent protein biosynthesis, including the correct folding and
188 acterial metabolism as well as mitochondrial protein biosynthesis, induce neutrophil chemotaxis, the
189 In this study, we found that inhibition of protein biosynthesis induced phosphorylation/activation
192 activates cell death only in the presence of protein biosynthesis inhibitors, which presumably block
196 imulation methods to explore Sec-facilitated protein biosynthesis is hindered by the large system siz
199 vents, indicating that, while the process of protein biosynthesis is orthologous, its constituents ar
201 talytic competency of the ribosome in extant protein biosynthesis is thought to arise primarily from
202 veals that RNA-based regulation of ribosomal protein biosynthesis is used in nearly all eubacterial p
203 (aa-tRNA) formation, an essential process in protein biosynthesis, is generally achieved by direct at
204 in a predicted C-terminal helical region for protein biosynthesis, localization, and interaction with
206 growth arrest, and suggest that restraining protein biosynthesis may be important in the prevention
211 ), matrix formation (n = 25), metabolism and protein biosynthesis (n = 27), cell signaling (n = 21),
212 enzymes that catalyze the first reaction in protein biosynthesis, namely the charging of transfer RN
213 anobacteria, plastids (chloroplasts) perform protein biosynthesis on bacterial-type 70S ribosomes.
216 oes not interfere with receptor binding or F protein biosynthesis or transport but prevents F protein
218 d several molecular 'programs' implicated in protein biosynthesis, oxidative-stress responses and NF-
219 n mechanisms that exist at every step of the protein biosynthesis pathway, such as alternative splici
220 l understanding of lipid synthesis, membrane protein biosynthesis, phospholipid and membrane protein
221 cellular transport, phospholipid metabolism, protein biosynthesis, protein localization, protein meta
223 ree-dimensional mRNA structure and regulates protein biosynthesis rates raises the possibility that s
224 limits of our knowledge regarding ribosomal protein biosynthesis regulation outside of E. coli, and
228 cell line up-regulated processes, including protein biosynthesis, responses to stress and responses
229 to quantitative or qualitative alteration of protein biosynthesis, secretion, activity, or clearance.
230 ing study, we show that H-MM is defined by a protein biosynthesis signature that is primarily driven
231 m that Aze is misincorporated for Pro during protein biosynthesis, specifically on cytosolically tran
232 into two broad categories; those that affect protein biosynthesis/stability and traffic to the cell s
234 The alpha-helical motif was not required for protein biosynthesis, tetrameric subunit assembly, tetra
237 is proteolytically processed by furin during protein biosynthesis, the S2' site is cleaved upon viral
239 id residues are bound to the ribosome during protein biosynthesis, these small proteins do not fold u
241 entails the manipulation of essential HIV-1 protein biosynthesis through unnatural amino acid (UAA*)
243 now possible to employ in vitro and in vivo protein biosynthesis to elaborate proteins containing a
245 egradation and calls for caution in blocking protein biosynthesis to study the half-life of proteins.
248 e proteins for methoxymalonyl-S-acyl carrier protein biosynthesis (Ttm-ABCDE), eight proteins for dia
249 sduction, vesicular and molecular transport, protein biosynthesis, ubiquitination, and neuronal survi
250 mportant for bacterial growth and functional protein biosynthesis under certain conditions and is qui
252 s in ubiquitin-dependent protein catabolism, protein biosynthesis, vesicle trafficking and the respon
253 this transporter (and other factors) in heme protein biosynthesis, we developed plasmids that produce
255 r necrosis factor-alpha (TNF-alpha) mRNA and protein biosynthesis were examined in adult feline myoca
259 In addition, other proteins involved in protein biosynthesis were shown to be associated with ri
260 ould represent an early intermediate in MoFe protein biosynthesis where the P-cluster precursors have
262 gy is regulated by processes occurring after protein biosynthesis, which are critical for both channe
263 thionine by methionyl-tRNA synthetase during protein biosynthesis, which results in the formation of
264 metabolism accommodated different levels of protein biosynthesis while maintaining a consistent rate
266 many studies have correlated deregulation of protein biosynthesis with cancer, it remains to be estab
267 r corroborated by showing that inhibition of protein biosynthesis with cycloheximide prior to 3-AP an
268 have a long history of providing probes into protein biosynthesis, with many of these compounds servi