ライフサイエンスコーパス: protein kinase C-epsilon

1 quency-dependent activation of PKC(epsilon) (protein kinase C epsilon).

2 andin E(2), emergence of novel dependence on protein kinase C epsilon.

3 hrome b561, glutathione s-transferase a4 and protein kinase C-epsilon.

4 noprecipitated from smooth muscle cells with protein kinase C-epsilon.

5 Because neutrophils do not express protein kinase C epsilon, a molecule recently reported a

6 These observations support protein kinase C epsilon activation as an essential comp

7 Protein kinase C epsilon activation in cardiac myocytes

8 lowering hepatic diacylglycerol content and protein kinase C epsilon activation through decreased SR

9 t-induced hepatic insulin resistance through protein kinase C epsilon activation, we next sought to u

10 sistance was accompanied by elevated hepatic protein kinase C-epsilon activation and blunted insulin-

11 targets of miR-143 (PDGF receptor alpha and protein kinase C epsilon) and miR-145 (fascin).

12 me when mitogen-activated protein kinase and protein kinase C-epsilon are targeted to the plasmalemma

13 um pathway and promotes translocation of the protein kinase C epsilon (epsilonPKC) isozyme and whethe

14 ptake of 125I-labeled calmodulin and a 20-kD protein kinase C epsilon fragment into the cells.

15 However, it is unclear whether protein kinase C epsilon function is required for normal

16 Targeted disruption of the protein kinase C epsilon gene blocked cardioprotection c

17 We examined hearts from protein kinase C epsilon knock-out mice under physiologi

18 otein kinase C delta activation increased in protein kinase C epsilon knock-out myocytes without alte

19 Protein kinase C epsilon may be one of the mediators con

20 ncentration, green fluorescent protein (GFP)-protein kinase C-epsilon mutants were tracked during pha

21 Protein kinase C epsilon, normally localized apically, w

22 lpha in subcutaneous tumors but not those of protein kinase C epsilon or protein kinase C zeta.

23 TnI was replaced with cTnI phosphorylated by protein kinase C-epsilon or mutated to cTnI-S43E/S45E/T1

24 protein kinase C-alpha and -zeta, but not of protein kinase C-epsilon, overexpressed in insect cells.

25 Protein kinase C epsilon (PKC epsilon ) acts as an antia

26 se require eicosanoid-mediated activation of protein kinase C epsilon (PKC epsilon) and that the majo

27 Recently, protein kinase C epsilon (PKC epsilon) has been identifi

28 metastatic squamous cell carcinoma (mSCC) in protein kinase C epsilon (PKC epsilon) transgenic mice w

29 Protein kinase C epsilon (PKC epsilon), a member of a fa

30 Protein kinase C-epsilon (PKC-epsilon) contains a putati

31 Protein kinase C-epsilon (PKC-epsilon) has been shown to

32 Protein kinase C-epsilon (PKC-epsilon) plays a central r

33 Protein kinase C-epsilon (PKC-epsilon) translocates to p

34 ith a blockade within hematopoietic cells of protein kinase C-epsilon (PKC-epsilon) up-regulation and

35 Protein kinase C-epsilon (PKC-epsilon) was previously im

36 e selective down-regulation in K562 cells of protein kinase C-epsilon (PKC-epsilon), which has recent

37 We have shown that protein kinase C(epsilon) (PKC(epsilon)), a Ca(2+)-indep

38 We identified protein kinase C epsilon (PKCepsilon encoded by the PRKC

39 ApoE3 also induced expression of protein kinase C epsilon (PKCepsilon) and PKCepsilon ret

40 Protein kinase C epsilon (PKCepsilon) AS-ODN also preven

41 Mice lacking protein kinase C epsilon (PKCepsilon) consume less alcoh

42 Here we show that protein kinase C epsilon (PKCepsilon) cooperates with th

43 stress to the fetus and results in decreased protein kinase C epsilon (PKCepsilon) expression in the

44 An essential role for protein kinase C epsilon (PKCepsilon) has been shown in

45 Protein kinase C epsilon (PKCepsilon) has emerged as an

46 oll-like receptor 4 (TLR4) and signaling via protein kinase C epsilon (PKCepsilon) in common, whereas

47 Protein kinase C epsilon (PKCepsilon) is emerging as a p

48 y pull-down assays, we found that myocardial protein kinase C epsilon (PKCepsilon) is physically asso

49 c increase in mRNA and protein levels of the protein kinase C epsilon (PKCepsilon) isozyme in primary

50 Previous results using protein kinase C epsilon (PKCepsilon) knockout mice, RNA

51 To determine the role that protein kinase C epsilon (PKCepsilon) may play in skin g

52 enhanced capsaicin-evoked responses involve protein kinase C epsilon (PKCepsilon) or phosphatidylino

53 We have previously shown that mice lacking protein kinase C epsilon (PKCepsilon) show decreased eth

54 We have previously shown that protein Kinase C epsilon (PKCepsilon) transgenic mice on

55 ere we demonstrated that mutant mice lacking protein kinase C epsilon (PKCepsilon) were more sensitiv

56 We found that protein kinase C epsilon (PKCepsilon), a member of the p

57 Protein kinase C epsilon (PKCepsilon), a novel PKC isofo

58 To explore the involvement of protein kinase C epsilon (PKCepsilon), a second messenge

59 (PKA) alone or through a combination of PKA, protein kinase C epsilon (PKCepsilon), and extracellular

60 duced by agonists at receptors that activate protein kinase C epsilon (PKCepsilon), occurs in male bu

61 D9 revealed a fragment of the gene, encoding protein kinase C epsilon (PKCepsilon), that was then sho

62 d to determine whether SIRT5 is activated by protein kinase C epsilon (PKCepsilon)-mediated increases

63 1,4,5-trisphosphate (IP(3)) receptors and/or protein kinase C epsilon (PKCepsilon).

64 xplored the sensitizing effects of epidermal protein kinase C epsilon (PKCepsilon)expression in the h

65 ycerol-mediated (DAG-mediated) activation of protein kinase C-epsilon (PKCepsilon) and the consequent

66 tabotropic glutamate receptor-5 (mGluR5) and protein kinase C-epsilon (PKCepsilon) expression in the

67 atrial fibrillation (AF), is mediated via a protein kinase C-epsilon (PKCepsilon)-dependent mechanis

68 Protein kinase C epsilon (PKCvarepsilon), a novel calciu

69 nes (SKH-1 hairless mice, wild-type FVB, and protein kinase C epsilon (PKCvarepsilon)-overexpressing

70 IgE-induced adhesion and spreading, whereas protein kinase C epsilon plays a negative role.

71 ing the locus containing the gene coding for protein kinase C-epsilon, previously implicated in model

72 d because of its phosphorylation mediated by protein kinase C epsilon (PRKCE) and ATM serine/threonin

73 nerated that overexpressed an epitope-tagged protein kinase C epsilon (T7-PKCepsilon) in their epider

74 press (approximately 18-fold) epitope-tagged protein kinase C-epsilon (T7-PKCepsilon) protein in the

75 phosphates and induces the translocation of protein kinase C epsilon to the myocyte membrane, consis

76 ting of mitogen-activated protein kinase and protein kinase C-epsilon to the surface membrane.

77 on, direct activation of protein kinase A or protein kinase C epsilon, two pathways that mediate infl