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1                     DAG activates RasGRP and protein kinase C theta.
2 of TAK1 and the CBM complex, but not IKK, to protein kinase C-theta.
3 cells and to the consequent stabilization of protein kinase C theta activation, resulting in the stim
4 ly impaired, the stimulation of Ras, ERK and protein kinase C-theta activities, as well as the mobili
5  This is paralleled by increased myocellular protein kinase C theta activity and serum fetuin A level
6 ctivation of NF-kappaB or phosphorylation of protein kinase C-theta, although T cell survival and pat
7 iated with relocalization of both NF-ATc and protein kinase C-theta among individual cells.
8 e necessary for efficient binding of PDK1 to protein kinase C-theta and the adaptor CARMA1 and thus f
9 tion of phosphoinosotide-dependent kinase 1, protein kinase C theta, and glycogen synthase kinase 3be
10 lation of ZAP70, phospholipase C-gamma1, and protein kinase C-theta, and impaired nuclear translocati
11 diminished expression of the Src kinase Lck, protein kinase C-theta, and NF-kappaB, key mediators of
12 vation that was dependent on Lck and/or Fyn, protein kinase C-theta, and RasGRP1.
13 ical model demonstrated that neuroendocrine, protein kinase C-theta, and triggering receptor expresse
14                      Because both RasGRP and protein kinase C theta are essential for thymocyte and T
15 requisite tyrosine kinases and Hck, Btk, and protein kinase C theta as contributory kinases in HC IgE
16 tory T cells has identified sequestration of protein kinase C theta away from the immune synapse as c
17  activity; TNFalpha exposure interferes with protein kinase C theta compartmentalisation, explaining
18 he antigen-specific T cell receptor involves protein kinase C-theta-dependent assembly of the CARMA1-
19                    The unique requirement of protein kinase C theta implies that signals emanating fr
20 storation of the IL-2 signaling cascade, via protein kinase C-theta overexpression, did.
21 osphoinhibition of GIV-GEF by the fatty acid/protein kinase C-theta pathway triggers IR.
22 arma1 in lipid rafts, which in turn recruits protein kinase C theta (PKC theta) and Bcl10 to the micr
23                                              Protein kinase C theta (PKC theta) is unique among PKC i
24                                          The protein kinase C theta (PKC theta) serine/threonine kina
25         Activation of T lymphocytes requires protein kinase C theta (PKC-theta) and an appropriately
26 , like antibodies to CD28, to synergize with protein kinase C theta (PKC-theta) in the induction of R
27 ly, T cell receptor (TCR) signaling molecule protein kinase C theta (PKC-theta)-mediated phosphorylat
28                                              Protein kinase C-theta (PKC-theta) is essential for matu
29                                              Protein kinase C-theta (PKC-theta) plays important roles
30                                              Protein kinase C-theta (PKC-theta) recruitment to the im
31                                              Protein kinase C-theta (PKC-theta) translocates to the c
32                             We now show that protein kinase C-theta (PKC-theta), a novel PKC isoform,
33 CARMA1-deficient T cells, the recruitment of protein kinase C-theta (PKC-theta), Bcl10, and IkappaB k
34 y activate a serine kinase cascade involving protein kinase C-theta (PKC-theta), leading to defects i
35 n this study, we show that in the absence of protein kinase C-theta (PKC-theta), superantigen (staphy
36                                     Although protein kinase C-theta (PKC-theta)-deficient mice are re
37 hosphatidylinositol 3-kinase (PI3-K)/Akt and protein kinase C-theta (PKC-theta).
38 he expression of a dominant active mutant of protein kinase C theta(PKC theta) induced strong SMRT-re
39 ological inhibition and genetic knockdown of protein kinase C theta (PKCo) inhibited signal transduce
40 nteractions triggered CD28 signaling through protein kinase C theta (PKCtheta) and promoted CD8(+) T
41                                              Protein kinase C theta (PKCtheta) has a central role in
42                  We investigated the role of protein kinase C theta (PKCtheta) in the activation of t
43 ological inhibition and genetic knockdown of protein kinase C theta (PKCtheta) inhibited signal trans
44    We report that the signaling intermediate protein kinase C theta (PKCtheta) is a diagnostic marker
45                                              Protein kinase C theta (PKCtheta) is a member of the nov
46                                              Protein kinase C theta (PKCtheta) is a novel Ca(2+)-inde
47         Previous reports have suggested that protein kinase C theta (PKCtheta) is essential for T-cel
48                                 In contrast, protein kinase C theta (PKCtheta) is not essential for e
49 MKK7) phosphorylation and recruitment to the protein kinase C theta (PKCtheta) signalosome and subseq
50 a lead from a high-throughput screen against protein kinase C theta (PKCtheta) through a series of op
51 bes treated with palmitate or overexpressing protein kinase C theta (PKCtheta), a kinase that has bee
52                                              Protein kinase C theta (PKCtheta), a member of the Ca(2+
53                                              Protein kinase C theta (PKCtheta)-deficient T cells also
54                                              Protein kinase C-theta (PKCtheta) is a Ca(2+)-independen
55                                              Protein kinase C-theta (PKCtheta) is a Ca(2+)-independen
56                  We reported previously that protein kinase C-theta (PKCtheta) is activated in GIST,
57                                              Protein kinase C-theta (PKCtheta) is an important compon
58                                              Protein kinase C-theta (PKCtheta) is critical for TCR-in
59                                              Protein kinase C-theta (PKCtheta) mediates critical T-ce
60                                              Protein kinase C-theta (PKCtheta) plays an important rol
61                      TBKBP1 recruits TBK1 to protein kinase C-theta (PKCtheta) through a scaffold pro
62 g through PI3K results in the recruitment of protein kinase C-theta (PKCtheta) to the cSMAC, activati
63                                We found that protein kinase C-theta (PKCtheta), a key signaling molec
64  T cells from TCR-transgenic mice crossed to protein kinase C-theta (PKCtheta)-deficient mice, we rep
65 oduct englerin A (EA) binds to and activates protein kinase C-theta (PKCtheta).
66 -APC contact area, where it colocalized with protein kinase C-theta (PKCtheta).
67 nregulated expression of the GIST biomarker, protein kinase C-theta (PRKCQ).
68 ut persists in cytolytic interactions, where protein kinase C-theta;, Src homology 2 domain-containin
69 vation of AP-1 and NF-kappaB is dependent on protein kinase C theta, suggesting the existence of a co
70 apse organization based upon localization of protein kinase C-theta, talin, and phospho-ZAP70.
71 h linker for activation of T cells (LAT) and protein kinase C-theta to the immunological synapse, i.e
72 site disrupts the ability of CD28 to recruit protein kinase C-theta; to the central supramolecular ac
73 tional iNKT cells requires signaling through protein kinase C theta, which is dispensable for convent
74 ansmigration of neutrophils by inhibition of protein kinase C-theta while not affecting selectin-medi
75 rough endothelial cells by inhibition of the protein kinase C-theta while not affecting the selectin-
76  dense arrays of ILPs (each enriched in TCR, protein kinase C-theta, ZAP70, phosphotyrosine, and HS1)