ライフサイエンスコーパス: protein motif

1 ed amino acids within the aldose 1-epimerase protein motif.

2 nction of both proteins and may define a new protein motif.

3 nsitive and assigned to a penicillin-binding protein motif.

4 t represents a multifunctional intracellular protein motif.

5 tanding of the major forces maintaining this protein motif.

6 ts that this PxxP segment can bind to an SH3 protein motif.

7 mino-acid units that lacks homology to known protein motifs.

8 f (RRM) is one of the most common eukaryotic protein motifs.

9 he two sequences and patterns of DNA-binding protein motifs.

10 ctions correspond to junctions of individual protein motifs.

11 AcMNPV)-induced bulk phosphorylation of S/TQ protein motifs.

12 approach to revealing biologically important protein motifs.

13 structures, phylogenetic relationships, and protein motifs.

14 es previously unrecognized rearrangements of protein motifs.

15 n in AHI1 is found in a region with no known protein motifs.

16 ed or decreased frequencies of particular SR protein motifs.

17 de sequence known as a PIP (PCNA interacting protein) motif.

18 From protein motifs(1) to black holes(2), topological soliton

19 deletion proteins, we now show that the Jak2 protein motif (231)YRFRR is required for the co-associat

20 Addition of the C2 protein motif (a structural domain found in proteins imp

21 encodes a polypeptide with two recognizable protein motifs: a RING domain near the N terminus and tw

22 informatics to identify cellular DNA-binding protein motifs adjacent to either latent or reactivation

23 on kinetics and RNA release suggest that the protein motifs affected by them have multiple roles in t

24 Specific protein motifs also point to a degree of homology with m

25 Phylogenetic and protein motif analyses mapped SpMae1(p) and AcDct(p) int

26 Transcriptome and protein motif analyses showed that approximately one-hal

27 Gene expression, protein motif and intron number were examined.

28 a robust multidomain scaffold with different protein motifs and activities contributing differentiall

29 ed in regulatory regions associated with MYC protein motifs and affect gene expression.

30 he course of this analysis, highly conserved protein motifs and domains within each of the AARS loci

31 Naturally occurring protein motifs and domains, including WWEs, PBZs, and ma

32 We also applied RABIT on RNA-binding protein motifs and found that some alternative splicing

33 nterpretation ability to analyze RNA-binding protein motifs and key signals on mRNAs for subcellular

34 t signatures in 3'UTR variation, RNA-binding protein motifs and miRNA expression associated with tran

35 loss by testing the importance of different protein motifs and partners in the developing CNS, where

36 sorghum (Sorghum bicolor), their phylogeny, protein motifs and promoter analysis.

37 D At A also contains protein motifs and protein similarities derived from sea

38 We deciphered the protein motifs and the machinery that regulates the LE t

39 These findings define a specific protein motif, and cellular condensates, that promote ta

40 ins, transforming growth factor-beta binding protein motifs, and two RGD binding sites.

41 paradigms attribute functions to particular proteins, motifs, and amino acids.

42 ated from the order in which the conserved G protein motifs appear in the sequence, the GTPase domain

43 These protein motifs appeared to be the regions where TnI-TnT

44 These protein motifs are derived from 7697 sequence alignments

45 A number of helix-rich protein motifs are involved in a variety of critical pro

46 Several proteins and protein motifs are known to be required for PtdSer trans

47 These protein motifs are suggested to mediate protein-protein

48 a database of protein families and conserved protein motifs) as well as manually adjusted multiple al

49 e molecular recognition of conserved RNA and protein motifs, as well as interactions that are crucial

50 nosoma cruzi and Leishmania major identified protein motifs associated with catalysis and protein or

51 d amino acid compositions and for particular protein motifs associated with known HRGPs.

52 lity with the design target, a betabetaalpha protein motif based on the polypeptide backbone structur

53 analysis helps to clarify how non-symmetric protein motifs bind to the double helix of DNA through t

54 ein, termed BCL7A, exhibited no recognizable protein motifs but showed homology with the actin-bindin

55 A protein motif called a PDZ domain is important in the ta

56 rates by interacting with a conserved target protein motif called the destruction box.

57 NC domain which closely resembles a cellular protein motif called the F-box domain.

58 of zinc finger proteins containing a unique protein motif called the positive regulatory (PR) domain

59 orithm is generally applicable to any DNA or protein motifs, can produce highly stable and biological

60 The FYVE domain is a conserved protein motif characterized by its ability to bind with

61 main is a largely uncharacterized tripartite protein motif conserved among eukaryotic proteins.

62 ns one double-stranded RNA-binding domain, a protein motif conserved among many double-stranded RNA-b

63 We identified a novel basic protein motif consisting of a cluster of three dibasic r

64 rombospondin type-1 repeats (TSRs) are small protein motifs containing six conserved cysteines formin

65 RHIM of RIPK3 is an intrinsically disordered protein motif, contrary to prediction, and that exchange

66 riants will help us determine which inversin protein motifs contribute to left-right asymmetry and ki

67 pears that the AT-hook motif is an auxiliary protein motif cooperating with other DNA-binding activit

68 ovel molecular basis for how a single, short protein motif could greatly modulate pathogen host tropi

69 side this conserved domain and no identified protein motifs could be deduced.

70 conserved domain database (CDD) and PROSITE protein-motif database improves COBALT's alignment quali

71 e basic region-leucine zipper (B-ZIP) (bZIP) protein motif dimerizes to bind specific DNA sequences.

72 re, we introduce this representation through protein motif discovery and protein sequence embedding.

73 NestedMICA, an open source protein motif discovery tool written in Java, is driven

74 ssification, sequence-function relationship, protein motif discovery, pathway interactions, and intri

75 As an archetype for protein motif-driven regulation of cell function, the AP

76 e regulatory elements, including RNA-binding protein motifs, eCLIP peaks, and microRNA sites, are up

77 The Slp1 protein contains a protein motif (EH1) which mediates binding to the transc

78 iting, nuclear pore composition, RNA-binding protein motif enrichment, and RNA secondary structure.

79 These basic protein motifs exhibit weak but physiologically relevant

80 tself to be a robust and sensitive ab initio protein motif finder, even for relatively short motifs t

81 ompared its performance with another popular protein motif finder, MEME.

82 In order to assess NestedMICA as a protein motif finder, we have tested it on synthetic dat

83 PRINTS is a compendium of protein motif 'fingerprints' derived from the OWL compos

84 Unlike ZFNs and TALENs that use protein motifs for DNA sequence recognition, CRISPR-Cas9

85 tial importance of lineage-specific genes or protein motifs for understanding traits shared across an

86 inger domain is a novel zinc-binding Cys-His protein motif found in a growing number of proteins invo

87 The dsRBM is a conserved protein motif found in many proteins from most organisms

88 ely 100 amino acid residues are a functional protein motif found in many signal-transducing and cytos

89 FF domains are poorly understood protein motifs found in all eukaryotes but in a very sma

90 dly, this work elucidates the role of common protein motifs found in carbohydrate-active enzymes that

91 oth deduced proteins contain three conserved protein motifs found in the active site of all eubacteri

92 In the present study, we combine protein motifs from several orthologs to engineer two va

93 ther proteins remain largely unknown, and no protein motifs have been identified as plasmodesmal targ

94 physiologically relevant occurrences of any protein motif identified in a eukaryotic proteome.

95 ces encoding the sterol-sensing domain (SSD) protein motif identified two sets of DNA sequences with

96 acids that couple RNA and ATP binding to the protein (Motif III).

97 0 amino acids consisting of three functional protein motifs implicated in vesicle transport and prote

98 y MHC molecules during natural processing of proteins, motifs important for selection of processed pe

99 pic interaction motif (RHIM) is an essential protein motif in inflammatory signaling and certain cell

100 The C2H2 zinc finger is the most prevalent protein motif in the mammalian proteome.

101 gen triple helix is one of the most abundant protein motifs in animals.

102 Amongst the most common protein motifs in eukaryotes are zinc fingers (ZFs), whi

103 of substrates and are one of the most common protein motifs in nature.

104 ene coregulated by 16E6 and NFX1-123 and the protein motifs in NFX1-123 that are important for this e

105 y has revealed the presence of two conserved protein motifs in the middle of the lumenal catalytic do

106 organization of exons which encode specific protein motifs in the mOST-PTP molecule.

107 We have examined conserved protein motifs in the non-coding, intergenic regions ("p

108 y method and evaluate the method for finding protein motifs in three different settings: (1) comparis

109 essing flexible paratopes that can recognize protein motifs inaccessible to classical antibodies, VNA

110 MRG15 contains several predicted protein motifs, including a nuclear localization signal,

111 Exon skips cause loss of inversin protein motifs, including ankyrin repeats, IQ domains, d

112 This work highlights universal membrane protein motifs, including lipid-protein interactions, do

113 rch against the BLOCKS database of conserved protein motifs indicates that Psdr1 retains features ess

114 ntains 289 motif classes and 3523 individual protein motif instances manually curated from 3467 scien

115 Moreover, a small protein motif interacts with five of these determinants,

116 the N-terminus of nNOS, which contains a PDZ protein motif, interacts with similar motifs in postsyna

117 complex contain tetratricopeptide repeats, a protein motif involved in protein/protein interactions.

118 ork describes a simple approach for studying protein motifs involved in the conversion of monomeric s

119 The highest probability matches were for protein motifs involved in transmembrane transport and e

120 The function of this protein motif is dependent on stretches of rare codons,

121 f pol eta, which contains a PCNA-Interacting Protein motif is required for pol eta to function in lag

122 that the Poleta C-terminal PCNA-interacting protein motif is required for the exchange process.

123 The versatile coiled-coil protein motif is widely used to induce and control macro

124 tructure can be recognized by many different protein motifs, it is not surprising that apparently unr

125 novel combination of a paired domain-related protein motif juxtaposed to a leucine zipper-like domain

126 -V-V) conforms to a sequence that binds to a protein motif known as the PDZ domain.

127 Encapsulation is mediated by specific cargo protein motifs known as targeting peptides (TPs), though

128 on the largest family of HEGs (encoding the protein motif, LAGLIDADG) to understand how HEGs and int

129 rwise highly conserved intermediate filament protein motif LNDR.

130 A protein motif located at the border of the SMAD-binding

131 Thus, this shared protein motif may play an analogous role in mediating th

132 A protein motif (MIN, for MRN inhibitor) inhibits MRN at b

133 We describe the use of Pfam protein motif models and the HMMER program to predict wh

134 MotifProp is based on a protein-motif network, in which edges connect proteins a

135 Despite the complex structure of the protein-motif network, MotifProp can be easily interpret

136 fied recombinant mosaic AGPases derived from protein motifs normally expressed in the maize (Zea mays

137 n a genetic pathway, and san and vtn contain protein motifs, NPxY and PTB domain, respectively, known

138 CT domain (for BRCA1 carboxyl terminus) is a protein motif of unknown function, comprising approximat

139 WW domains are conserved protein motifs of 38-40 amino acids found in a broad spe

140 uman sequences reveals that the recognizable protein motifs of BARD1 are well conserved, including th

141 adenovirus E4 ORF1 proteins lacked conserved protein motifs of dUTPase enzymes or detectable enzymati

142 tagenesis studies, we further identified the protein motifs on TOB and PABPC1 that are necessary for

143 rine, and 6% methionine, but no recognizable protein motifs or significant homologies to any other kn

144 (formerly thought exclusively nuclear); this protein motif organization is unprecedented.

145 The F-box represents a protein motif originally identified as a conserved amino

146 terminal domain binds lipids through a novel protein motif, permitting complexin to inhibit spontaneo

147 TMEM189 proteins contain a conserved protein motif (pfam10520) with eight conserved histidine

148 oliferating-cell-nuclear-antigen-interacting protein motif (PIP-box) and the KEN-box (recognized by t

149 m-designed Cyanorak Roles as well as several protein motif predictions.

150 erminal domain, individual cullins bind to a protein motif present in multiple proteins to recruit sp

151 as found to be induced by the leucine zipper protein motif, rather than structural distortions of DNA

152 emerging family of proteins sharing a set of protein motifs referred to as PET-LIM domains.

153 Protein motifs represent highly conserved regions within

154 cterized Rbf1 turnover in Drosophila and the protein motifs required for its destabilization.

155 A search for functionally significant protein motifs revealed consensus sequences for N-glycos

156 ligand domain involving both sialic acid and protein motif(s).

157 We have combined protein motif search and gene finding methods to identif

158 ncy similarity search by using BLASTN, and a protein motif search of the human ORFeome by using hidde

159 bidopsis genomic sequences and new Blast and protein motif search results.

160 ents of inferred protein sequences, DNA, and protein motif searches and protein secondary structure p

161 searches of pre-computed BLAST results, and protein motif searches.

162 ntified 18 ULK1-specific and 7 ULK2-specific protein motifs serving as different interaction interfac

163 was identified with a potential RNA binding protein motif similar to sex lethal that appears to have

164 We report that multiple short linear protein motifs (SLiMs) within intrinsically disordered r

165 most of the short (3-9 amino acid long) test protein motifs spiked into a test set of sequences at di

166 dered a likely candidate on the basis of its protein motif structure and expressed-sequence-tag repre

167 Analysis of protein motif structure of the Dof paralogs and their an

168 c domains of Ets proteins interact with many protein motifs such as bHLH, bZipper and Paired domain.

169 hlights the flexibility of core cytoskeletal protein motifs, such that one type of cytoskeletal eleme

170 ar expression of Ma proteins and analysis of protein motifs suggest that these proteins play roles in

171 to protease trafficking and suggests that a protein motif targeting signal for lysosomal proteases a

172 We identified a novel conserved protein motif, termed the "leucine latch," at the N term

173 trate the use of Suns to interactively build protein motifs, tertiary interactions, and to identify s

174 e alpha-helical coiled coil (CC) is a common protein motif that because of the simplicity of its sequ

175 oreover, the widely utilized TIR domain is a protein motif that can possess enzymatic activity.

176 The PR domain is a newly recognized protein motif that characterizes a subfamily of Kruppel-

177 These findings define a novel protein motif that functions in intracellular calcium si

178 be explained by their possession of a common protein motif that interacts with a binding site on prot

179 ins the nuclear matrix targeting signal, the protein motif that is necessary and sufficient to target

180 stablish the nucleosomal binding domain as a protein motif that is present in other than just the ubi

181 genetic approach, we have uncovered a novel protein motif that limits the transcriptional synergy of

182 sequence, creating a regulatable RNA-binding protein motif that retains its functional activity.

183 Motif III is one of the seven protein motifs that are characteristic of superfamily I

184 The active site is composed of six protein motifs that are conserved in order and spacing a

185 their PDX1 counterparts but contain several protein motifs that are conserved throughout all PDX2 pr

186 dent eEF1A mutations localize close to the G-protein motifs that are crucial for nucleotide binding.

187 e and other ABC transporters reveals several protein motifs that are highly conserved both in sequenc

188 ave examined the expression of 20 genes with protein motifs that are strongly conserved within the Sp

189 e (EGF) repeats are also small cysteine-rich protein motifs that can be O-glycosylated by several ER-

190 that Notch-like EGF and discoidin/C domains, protein motifs that facilitate a variety of cellular int

191 We identified a protein motif, the DWD box (DDB1-binding WD40 protein),

192 Here, we describe a protein motif, the GTB motif (for G1/S transcription fac

193 es respect neither functional nor structural protein motifs, the introns appear to be relatively rece

194 mino acid propensities for another important protein motif: the collagen triple-helix conformation wi

195 f mediating specific pairing of a widespread protein motif: the parallel, dimeric, alpha-helical coil

196 We analyze a variety of repeating protein motifs, TIM barrels, propellor blades, coiled co

197 representations, automatically detecting key protein motifs to provide meaningful interpretations.

198 yrosine-rich protein (FYRP), both containing protein motifs typically found on chromatin proteins.

199 Through inclusion of a photocleavable protein motif, we further establish that visible light c

200 Drosophila Ftz proteins with mutated protein motifs were expressed under the control of a neu

201 Models for three cadherin protein motifs were generated from over 100 already anno

202 Three conserved protein motifs were identified by aligning the VP3 and V

203 The AT-hook is a small DNA-binding protein motif which was first described in the high mobi

204 the evolutionary origins of this ubiquitous protein motif, which is found soluble exclusively as an

205 Cpk proteins do not contain any recognizable protein motif, while the C termini contain "C2 domains,"

206 cible domain, a small, genetically encodable protein motif whose structure is dependent on its tyrosi

207 Protein motifs with established functions found in CRTs

208 maize NBS1 orthologues that share conserved protein motifs with human NBS1.

209 Previous work demonstrated a beta-hairpin protein motif within this region to be responsible for D