ライフサイエンスコーパス: protein phosphatase

1 in reduces ERK activity via recruitment of a protein phosphatase.

2 was identified as an enzyme regulating sperm protein phosphatase.

3 pagation, little is known about the relevant protein phosphatases.

4 TPase activation by inhibiting PP2C.D family protein phosphatases.

5 Nuclear inhibitor of protein phosphatase 1 (NIPP1) is a ubiquitously expresse

6 ysis of the Plasmodium falciparum homolog of Protein Phosphatase 1 (PfPP1), a universally conserved c

7 trin homology domain and leucine-rich repeat protein phosphatase 1 (PHLPP1) as a regulatory phosphata

8 gene encoding PH domain Leucine-rich repeat Protein Phosphatase 1 (PHLPP1) protects mice from lethal

9 homology (PH) domain and leucine-rich repeat protein phosphatase 1 (Phlpp1) regulates protein kinase

10 la border cell migration model, we find that Protein phosphatase 1 (Pp1) activity controls collective

11 these events that we show are underpinned by protein phosphatase 1 (PP1) activity, the inhibition of

12 Evidence suggests that protein phosphatase 1 (PP1) and other protein phosphatas

13 cAMP-dependent protein kinase (PKA) and the protein phosphatase 1 (PP1) and/or PP2A.

14 We found that RIF1 mutants that block Protein Phosphatase 1 (PP1) binding activated telomeric

15 The serine-threonine protein phosphatase 1 (PP1) deactivates this pathway whe

16 acid, implicating PDGF-induced activation of protein phosphatase 1 (PP1) in CRMP2 regulation.

17 Here we show in vitro and in Drosophila that Protein Phosphatase 1 (PP1) inactivates Mps1 by dephosph

18 regulatory subunit 1A (PPP1R1A) is a potent protein phosphatase 1 (PP1) inhibitor; however, its role

19 In particular, protein phosphatase 1 (PP1) is recruited to a DSB-mimick

20 Protein phosphatase 1 (PP1) limits steady-state phosphor

21 ly, pharmacological or genetic inhibition of protein phosphatase 1 (PP1) prevented HTTex1 aggregation

22 Repo-Man is a protein phosphatase 1 (PP1) targeting subunit that regul

23 ctr1, an actin-binding protein that recruits protein phosphatase 1 (PP1) to certain phosphoprotein su

24 he mitotic chromosome periphery and recruits protein phosphatase 1 (PP1) to chromatin at anaphase ons

25 Biochemically, Dok3 recruited protein phosphatase 1 (PP1) to dephosphorylate Card9, an

26 The Ska1 C-terminal domain (CTD) recruits protein phosphatase 1 (PP1) to kinetochores to promote t

27 etaphase II due to premature localization of protein phosphatase 1 (PP1) to kinetochores, which antag

28 ew study, we investigated the interaction of protein phosphatase 1 (PP1) with the SR protein splicing

29 this study we show that Gwl associates with protein phosphatase 1 (PP1), particularly PP1gamma, whic

30 The metalloenzyme protein phosphatase 1 (PP1), which is responsible for >=

31 C and error correction are both regulated by protein phosphatase 1 (PP1), which silences the SAC and

32 osphatase 2 phosphatase activator (PP2A) and protein phosphatase 1 (PP1).

33 ylation-mediated decrease in the activity of protein phosphatase 1 (PP1).

34 found that this motif is sufficient to bind protein phosphatase 1 (PP1)alpha, a ubiquitously express

35 (TTN) is highly selective for a single PPP, protein phosphatase 1 (PP1/PPP1C).

36 rate specificity of the catalytic subunit of protein phosphatase 1 (PP1c) is dictated by PP1c-interac

37 by inhibition of the catecholamine-sensitive protein phosphatase 1 and decreased by beta-blocker pret

38 h reductions in G-protein receptor kinase 2, protein phosphatase 1 and protein phosphatase 2 A abunda

39 Pi04314 interacts with three host protein phosphatase 1 catalytic (PP1c) isoforms, causing

40 oduct of which recruits the alpha-isoform of protein phosphatase 1 catalytic subunit (PP1alpha) and e

41 lls to isolate NACA complexes and identified protein phosphatase 1 catalytic subunit alpha (PP1A) as

42 Furthermore, we identified protein phosphatase 1 catalytic subunit gamma (PPP1CC) a

43 ch is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2

44 MBS85), paxillin and CPI-17 (PKC-potentiated protein phosphatase 1 inhibitor protein of 17 kDa) phosp

45 est whether a DCT-enriched inhibitor of PP1, protein phosphatase 1 inhibitor-1 (I1), mediates cAMP's

46 etermined the expression and localization of protein phosphatase 1 regulatory inhibitor subunit 11 (P

47 tic cancer cells had increased expression of protein phosphatase 1 regulatory inhibitor subunit 1B (P

48 Protein phosphatase 1 regulatory subunit 1A (PPP1R1A) is

49 Protein phosphatase 1 regulatory subunit 1B(+) BLA pyram

50 Expression patterns were confirmed for protein phosphatase 1 regulatory subunit 36 (PPP1R36) an

51 ction closest to the mapped region, PPP1R3B (protein phosphatase 1 regulatory subunit 3B), encodes a

52 The MYPTs preferentially bind the catalytic protein phosphatase 1 subunit PP1cbeta, forming myosin p

53 -ASPP2 was dependent on its interaction with protein phosphatase 1, but not on t-ASPP2-induced YAP ac

54 se 5 (Cdk5), glycogen synthase kinase 3beta, protein phosphatase 1, or protein phosphatase 2A, but re

55 h de novo loss-of-function (LoF) variants in protein phosphatase 1, regulatory subunit 12a (PPP1R12A)

56 between TIBC and a variant near the gene for protein phosphatase 1, regulatory subunit 3B (PPP1R3B; r

57 s dephosphorylation by kinetochore-localized protein phosphatase 1, which allows Cdc20 to activate th

58 h differential activity of eIF2B mediated by protein phosphatase 1.

59 sphorylation-dependent mechanism mediated by protein phosphatase-1 (PP1) and dual specificity phospha

60 evelopment of a photoreleasable version of a protein phosphatase-1 (PP1)-disrupting peptide (PDP-Nal)

61 s mediated at least in part by inhibition of protein phosphatase-1 (PP1c) via persulfidation at Cys-1

62 )-disrupting peptide (PDP-Nal) that triggers protein phosphatase-1 activity.

63 coded by the PPP1R1B gene is an inhibitor of protein phosphatase-1 and protein kinase A.

64 in phosphatase (MP) holoenzyme consisting of protein phosphatase-1 catalytic subunit (PP1c) and MP ta

65 Increased protein phosphatase-1 in heart failure (HF) induces mole

66 Inhibiting protein phosphatase-1 through the overexpression of a co

67 c were determined to be potent inhibitors of protein phosphatase-1 with similar activity.

68 at involves the phosphatases calcineurin and protein phosphatase-1, as well the serine/threonine kina

69 e isolation membrane, and by redirecting the protein phosphatase 1alpha (PP1alpha) to dephosphorylate

70 We show that AR recruits protein phosphatase 1alpha (PP1alpha), resulting in P-TE

71 ted after PTH stimulation, and we found that protein phosphatase 1alpha (PP1alpha), which binds NHERF

72 t mortalin can regulate MEK/ERK activity via protein phosphatase 1alpha (PP1alpha).

73 Protein phosphatase 1alpha interacts with a novel ciliar

74 opsis (Arabidopsis thaliana) Shewanella-like protein phosphatase 2 (AtSLP2) is a bona fide Ser/Thr pr

75 uppressor PPP2R2A, a B regulatory subunit of protein phosphatase 2 (PP2A), determines sensitivity to

76 t, and mass spectrometry analysis identified protein phosphatase 2 A (PP2A) as one of the top ATG-int

77 how the potential of LB100, a small-molecule protein phosphatase 2 A (PP2A) inhibitor, as a monothera

78 'gamma) subunit of an essential host enzyme, protein phosphatase 2 A (PP2A), is repurposed as an inte

79 rylating Tau at AD specific phospho-sites is protein phosphatase 2 A (PP2A).

80 receptor kinase 2, protein phosphatase 1 and protein phosphatase 2 A abundance following phosphodiest

81 e B56gamma subunit of its human host factor, protein phosphatase 2 A.

82 f REGgamma increases the stability of PP2Ac (protein phosphatase 2 catalytic subunit) in vitro and in

83 ll cycle arrest, and DNA damage and inhibits protein phosphatase 2 phosphatase activator (PP2A) and p

84 Protein phosphatase 2 phosphatase activator (PP2A) and p

85 ng from our previous observations that PP2A (protein phosphatase 2) regulates the HIF (hypoxia-induci

86 ine on relaxation rate and the expression of protein phosphatase 2.

87 d by proteins such as cancerous inhibitor of protein phosphatase 2A (CIP2A), protein phosphatase meth

88 endometrial cancers harbor mutations in the protein phosphatase 2A (PP2A) Aalpha scaffold subunit en

89 Somatic missense mutations in the Ser/Thr protein phosphatase 2A (PP2A) Aalpha scaffold subunit ge

90 Somatic mutation of the protein phosphatase 2A (PP2A) Aalpha-subunit gene PPP2R1

91 Furthermore, we found that a lower protein phosphatase 2A (PP2A) activity, a phosphatase re

92 A-depleted cells was the result of increased protein phosphatase 2A (PP2A) activity.

93 Here, we show that protein phosphatase 2A (PP2A) acts as opsin phosphatase

94 Here we show that cytoplasm-localized protein phosphatase 2A (PP2A) B' regulatory subunits int

95 Protein phosphatase 2A (PP2A) complexes counteract many

96 Protein phosphatase 2A (PP2A) critically regulates cell

97 Protein phosphatase 2A (PP2A) dephosphorylates several t

98 kinase 1 (RACK1) as the regulatory subunit, protein phosphatase 2A (PP2A) dephosphorylates threonine

99 Protein phosphatase 2A (PP2A) enzymes can suppress tumor

100 Observed deficits in protein phosphatase 2A (PP2A) function in a variety of h

101 The serine/threonine Protein Phosphatase 2A (PP2A) functions as a tumor suppr

102 ivation chaperones control the biogenesis of protein phosphatase 2A (PP2A) holoenzymes that contain a

103 the role of the receptor and its associated protein phosphatase 2A (PP2A) in macrophage activation.

104 rectly assessed the contribution of CD25 and protein phosphatase 2A (PP2A) in promoting IL-2R signali

105 Protein Phosphatase 2A (PP2A) is a heterotrimer composed

106 Protein phosphatase 2A (PP2A) is a key signaling compone

107 Protein phosphatase 2A (PP2A) is a large enzyme family r

108 Protein phosphatase 2A (PP2A) is a member of the intrace

109 Protein phosphatase 2A (PP2A) is a serine/threonine phos

110 The tumor suppressor protein phosphatase 2A (PP2A) is a serine/threonine phos

111 Herein, cellular serine/threonine protein phosphatase 2A (PP2A) is identified as a functio

112 The recruitment of substrates by the ser/thr protein phosphatase 2A (PP2A) is poorly understood, limi

113 cer of zeste, trithorax (SET)/inhibitor 2 of protein phosphatase 2A (PP2A) oncoprotein binds and inhi

114 termed "targeted chemotherapy" by depleting protein phosphatase 2A (PP2A) or its inhibition using a

115 Protein phosphatase 2A (PP2A) plays important roles in c

116 Protein phosphatase 2A (PP2A) presents unique opportunit

117 We identify Bbeta2, a mitochondria-localized protein phosphatase 2A (PP2A) regulatory subunit, as a n

118 Protein phosphatase 2A (PP2A) represses many oncogenic s

119 Since MID1 ubiquitinates protein phosphatase 2A (PP2A), a negative regulator of m

120 ated that activation of the tumor suppressor protein phosphatase 2A (PP2A), a negative regulator of m

121 tors that could synergize with activation of protein phosphatase 2A (PP2A), a tumor suppressor phosph

122 f key regulators of hepatic gluconeogenesis, protein phosphatase 2A (PP2A), AMP-activated protein kin

123 xes that appear to act through regulation of protein phosphatase 2A (PP2A), but their functions in ma

124 Mechanistically, PI3Kgamma sequesters protein phosphatase 2A (PP2A), disrupting ERK-PP2A inter

125 a protein complex containing Aldob, Akt, and protein phosphatase 2A (PP2A), leading to inhibition of

126 suppression of protein phosphatases, such as protein phosphatase 2A (PP2A), that normally counteract

127 Protein phosphatase 2A (PP2A), YAP, Src family tyrosine

128 Here we report that MEF2 induces a Protein phosphatase 2A (PP2A)-mediated dephosphorylation

129 ifications, make it a nanomolar inhibitor of protein phosphatase 2A (PP2A).

130 repression and required for association with protein phosphatase 2A (PP2A).

131 Gcn4 is dephosphorylated by the protein phosphatase 2A (PP2A); our data show that when m

132 otic entry biochemical regulators, including protein phosphatase 2A (PP2A-B55/SUR-6), biophysical reg

133 tors of IRF3 and STAT1 activities, including protein phosphatase 2A (PPP2CA) and tripartite motif-con

134 P levels and attenuates protein kinase A and protein phosphatase 2A activities.

135 comprised of the southern hemisphere against protein phosphatase 2A are described.

136 vity through the androgen receptor-STK4/MST1-protein phosphatase 2A axis, which may have important im

137 yeasts to be mediated by recruitment of the protein phosphatase 2A B' (PP2A B').

138 t, Cdr2-T166 phosphorylation is regulated by protein phosphatase 2A but not by the Sds23-PP6 pathway.

139 Furthermore, we noted that protein phosphatase 2A can interact with TET2 and dephos

140 as driven by dysfunction of serine/threonine protein phosphatase 2A in the nerve terminals.

141 Protein phosphatase 2A mediated the reduction in NF-kapp

142 on was conferred by Pak2 inhibition of PP2A (protein phosphatase 2A) activity.

143 re administered chemical modulators of PP2A (protein phosphatase 2A) activity.

144 3 (p90 ribosomal S6 kinase type 3) and PP2A (protein phosphatase 2A) at signalosomes organized by the

145 (armadillo/huntingtin, elongation factor 3, protein phosphatase 2A, and the yeast kinase TOR1) or BE

146 /MST1) signaling, stimulates the activity of protein phosphatase 2A, and thereby attenuates the phosp

147 hase kinase 3beta, protein phosphatase 1, or protein phosphatase 2A, but reduces p35 subunit of Cdk5.

148 ties of tau kinases and phosphatases such as protein phosphatase 2A, irrespective of fisetin treatmen

149 strate that B55beta, a regulatory subunit of protein phosphatase 2A, represents a molecular link betw

150 ctivity of the serine/threonine phosphatase, protein phosphatase 2A, which operates at the intersecti

151 ice lacking the Bbeta2 regulatory subunit of protein phosphatase 2A, which we have shown previously a

152 itory effect was caused by BTK inhibition of protein phosphatase 2A-mediated (PP2A-mediated) dephosph

153 ) sensor calmodulin, protein kinase CK2, and protein phosphatase 2A.

154 up a CAR surface, allowing interaction with protein phosphatase 2A.

155 key regulatory subunit (B56alpha) of the PP (protein phosphatase) 2A holoenzyme displayed aberrant ac

156 Protein phosphatase-2A (PP2A) is an abundant serine/thre

157 in protein kinase A dependent activation of protein phosphatase-2A (PP2A).

158 lance of CaMKII-mediated phosphorylation and protein phosphatase 2B (PP2B)-mediated dephosphorylation

159 in the non-miR-185 targets serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform,

160 , together with a plant-specific subclade of protein phosphatase 2C (PP2C), form functional holorecep

161 prising a PYRABACTIN RESISTANCE 1-like (PYL)-PROTEIN PHOSPHATASE 2C (PP2C)-SNF1-RELATED PROTEIN KINAS

162 26 is modulated by GSK3-like kinase BIN2 and protein phosphatase 2C ABI1.

163 The clade A protein phosphatase 2C Highly ABA-Induced 1 (HAI1) plays

164 ors, which alleviates negative regulation by protein phosphatases 2C (PP2Cs) of the protein kinase OP

165 eventing its inhibitory dephosphorylation by protein phosphatase-2C rather than inducing de novo kina

166 mitogen-activated protein kinase 6, probable protein phosphatase 2C1, probable trehalose-phosphate ph

167 Protein phosphatase 4 (PP4) dephosphorylates 53BP1 in la

168 gular sites along chromosomes while ablating Protein Phosphatase 4 had the opposite effect.

169 uces an increase in calcium, which activates protein phosphatase 4 that in turn dephosphorylates HDAC

170 al differentially expressed proteins, namely protein phosphatase 5 (PP5), formyl peptide receptor 2,

171 nt LATS interaction with and inactivation by protein phosphatase 5.

172 In addition, protein phosphatase-5 (PP5) increased its association wi

173 1), in conjunction with the serine/threonine protein phosphatase 5C (PPP5C), inhibits I(SOC) .

174 and this phosphosite is dephosphorylated by protein phosphatase 6.

175 Two of them belong to clade A of type 2C protein phosphatases: ABA-HYPERSENSITIVE GERMINATION 1 (

176 When the ABA signal terminates, protein phosphatases ABI1/2 promote rapid degradation of

177 indirect inhibition of any one of three PP2C protein phosphatases (ABI2, PP2CA, HAB1) by cytosolic Ca

178 e ABA signaling pathway in which A-type PP2C protein phosphatases act as central negative modulators.

179 hree Clade E Growth-Regulating (EGR) Type 2C protein phosphatases act as negative growth regulators t

180 Further, Fig4 is also a protein phosphatase acting on PIKfyve to stimulate its l

181 hosphatase activity or both PTEN's lipid and protein phosphatase activities.

182 N function in ICL repair is dependent on its protein phosphatase activity and ability to be SUMOylate

183 d concomitant with a significant increase in protein phosphatase activity for two colon cancer cell l

184 lipid phosphatase activity, a role for PTEN protein phosphatase activity in cell cycle regulation ha

185 tophosphorylation in its activation and PTEN protein phosphatase activity in governing glycolysis and

186 In this study, we demonstrate that PTEN's protein phosphatase activity is required for epiblast ep

187 The protein phosphatase activity of PTEN dephosphorylates an

188 iety of PTEN mutant constructs, we show that protein phosphatase activity of PTEN targets PTK6, with

189 PTEN protein has lipid phosphatase and protein phosphatase activity, as well as other functions

190 transcriptional coactivators with intrinsic protein phosphatase activity.

191 racterized, the biological relevance of PTEN protein-phosphatase activity remains undefined.

192 R) levels, which are rescued by loss of PTEN protein-phosphatase activity to restrain cell survival.

193 y tumorigenesis, the additional loss of PTEN protein-phosphatase activity triggered an extensive cell

194 ence that DOG1 can interact with the type 2C protein phosphatases AHG1 and AHG3 and that this represe

195 Y68 frame shift, leading to the loss of PTEN protein phosphatase and lipid phosphatase activities.

196 lated Pah1 was a substrate for the Nem1-Spo7 protein phosphatase and was degraded by the 20S proteaso

197 nsisting of PYR/PYL/RCAR ABA receptors, PP2C protein phosphatases and SnRK2 protein kinases has led t

198 tes, but how these multiple protein kinases, protein phosphatases, and ubiquitin ligases are coordina

199 ely, suppressor of cytokine signaling (SOCS) proteins, phosphatases, and protein inhibitor of activat

200 Protein phosphatases are involved in embryonic developme

201 st via involvement of the Aup1 mitochondrial protein phosphatase, as well as 2 known matrix-localized

202 Noting that Ca2+/CaM and protein phosphatases bind CaMKII at nearby or overlappin

203 effector for the Ca(2+)/calmodulin-dependent protein phosphatase calcineurin (CaN, PP2B, and PPP3).

204 strongly associated with proteolysis of the protein phosphatase calcineurin (CN) and the elevated ex

205 Finally, we show that the calcium-activated protein phosphatase calcineurin dephosphorylates Hoxb13

206 gesting that inhibitors against the upstream protein phosphatase calcineurin should be effective for

207 including the molecular chaperone Hsp90, the protein phosphatase calcineurin, and the small GTPase Ra

208 n increase in the expression/activity of the protein phosphatase calcineurin.

209 The calcium-dependent protein phosphatase, calcineurin (CaN), has been implica

210 We demonstrate that the NE protein phosphatase, CNEP-1/CTDNEP1, controls de novo gl

211 ted this specificity and found that distinct protein phosphatases counteract Ssp1 activity toward its

212 ompare model scenarios in which Ca2+/CaM and protein phosphatase do or do not structurally exclude ea

213 show that CREMalpha induces dual specificity protein phosphatase (DUSP) 4 in effector CD4(+) T cells

214 qPCR) was used to determine dual specificity protein phosphatase (Dusp)-1 mRNA induction by Auranofin

215 Overall, our data define Pptc7 as a protein phosphatase essential for proper mitochondrial f

216 obe binding of calcineurin (CN), a conserved protein phosphatase essential for the immune response an

217 Cell detachment induces several protein phosphatases, five of which - DUSP6, PPTC7, PTPN

218 on of Gadd34 (Ppp1r15A),which targets type 1 protein phosphatase for dephosphorylation of eIF2alpha-P

219 Overexpression of the poplar PP2C protein phosphatase gene PtrHAB2 resulted in increased t

220 n factor, HSF-1, disrupts the JUN kinase and protein phosphatase I equilibrium which increases ACT-5

221 e characterize a mitochondrial IMS-localized protein phosphatase identified in photosynthetic eukaryo

222 vidence supports an involvement of activated protein phosphatase in executing the dephosphorylation d

223 entify a novel role of PTPRF as an oncogenic protein phosphatase in supporting the activation of Wnt

224 us on comprehensively identifying and naming protein phosphatases in available apicomplexan genomes,

225 Impairment of protein phosphatases, including the family of serine/thr

226 that silencing of GhDsPTP3a, which encodes a protein phosphatase, increases cotton tolerance to salt

227 presence of micromolar concentrations of the protein phosphatase inhibitor okadaic acid, implicating

228 Protein phosphatase inhibitors are often considered as t

229 The Highly ABA-Induced 1 (HAI1) protein phosphatase is a central component of drought-re

230 also inhibited the increase, implying that a protein phosphatase is involved.

231 In a previous study, we showed that the protein phosphatase is subject to phosphorylation by pro

232 contacts through the receptor-type tyrosine-protein phosphatases kappa led to acquisition of a full

233 B15, belonging to the clade A PP2C family of protein phosphatases known to regulate abscisic acid (AB

234 inhibitor of protein phosphatase 2A (CIP2A), protein phosphatase methylesterase 1 (PME-1), and SET nu

235 The common rs1440581 T allele in the protein phosphatase Mg2+/Mn2+ dependent 1K (PPM1K) gene

236 s that protein phosphatase 1 (PP1) and other protein phosphatases modulate NCC phosphorylation, but l

237 disrupts binding to MKP3, a dual-specificity protein phosphatase negatively regulating ERK function.

238 e investigate the oncogenic role of PPM1D, a protein phosphatase often found truncated in pediatric g

239 he phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP) downstream of PTEN is highly

240 onstrated that PH domain leucine-rich repeat protein phosphatase (PHLPP), a novel family of Ser/Thr p

241 eins via hyperactivation of the Mn-dependent protein phosphatase PhpP, a key enzyme involved in the r

242 The data imply that an allosteric SR protein-phosphatase platform balances phosphorylation le

243 Cdc14 protein phosphatases play an important role in plant inf

244 osphatase (PHLPP), a novel family of Ser/Thr protein phosphatases, plays an important role in regulat

245 A activity, whereas dephosphorylation by the protein phosphatases PP-1 and PP-2B (calcineurin) revers

246 hanges in the levels of the serine/threonine-protein phosphatase PP1-alpha catalytic subunit or prote

247 phosphorylation by allosterically inhibiting protein phosphatase PP1:PPP1R15A.

248 the spindle assembly checkpoint involves two protein phosphatases, PP1 and PP2A-B56, that are thought

249 The conserved heterotrimeric protein phosphatase PP2A controls the timing of events i

250 hat KAP1 (KRAB-associated protein 1) and the protein phosphatase PP2A interact with URI.

251 ARPP-16, ARPP-19, and ENSA are inhibitors of protein phosphatase PP2A.

252 caffolding A subunit of the serine/threonine protein phosphatase, PP2A, and that phosphorylation of A

253 tor of certain forms of the serine/threonine protein phosphatase, PP2A, when phosphorylated by the ki

254 rylation is counteracted by the main cardiac protein phosphatases, PP2A and PP1.

255 Type 2A protein phosphatases (PP2As) are highly expressed in the

256 RNA (SAUR) proteins inhibit D-CLADE TYPE 2C PROTEIN PHOSPHATASE (PP2C.D) activity, thereby trapping

257 vated by ABA-triggered inhibition of type-2C protein-phosphatases (PP2Cs).

258 ys were used to assess the expression of the protein phosphatase PP5 in endobronchial biopsies and AS

259 Ppz Ser/Thr protein phosphatases (PPases) are found only in fungi an

260 of the magnesium-dependent serine/threonine protein phosphatase (PPM) family and is induced by P53 i

261 phosphatases revealed that a poorly studied protein phosphatase, PPM1H, counteracts LRRK2 signaling

262 ase domain related to the eukaryotic phospho-protein phosphatase (PPP) family.

263 I-mediated signaling, consisting of WHIP and protein phosphatase PPP6C.

264 Protein phosphatases (PPs) also regulate DAT activity, b

265 While it is known that Ser/Thr protein phosphatases prefer pThr over pSer, we show that

266 port that Sds23, an inhibitor of PP2A family protein phosphatases, promotes the symmetric division of

267 tochondrial targeting of protein kinases and protein phosphatases provides a means to locally control

268 Protein phosphatase PstP is conserved throughout the Act

269 Unlike kinases, protein phosphatases remain understudied and less charac

270 x in the yeast Saccharomyces cerevisiae is a protein phosphatase required for the nuclear/endoplasmic

271 An siRNA screen of all human protein phosphatases revealed that a poorly studied prot

272 tive HCO(3)(-)-sensor receptor-type tyrosine-protein phosphatase RPTPgamma, which enhances endothelia

273 EMENT In the present study, we show that the protein phosphatase Shp2 is an important mediator of oli

274 Very little is known about how Ser/Thr protein phosphatases specifically recruit and dephosphor

275 In cancer, suppression of protein phosphatases, such as protein phosphatase 2A (PP

276 ed in photosynthetic eukaryotes as well as a protein phosphatase target of the highly conserved eukar

277 lancing the expression levels of an unstable protein phosphatase that antagonizes phosphorylation of

278 x in the yeast Saccharomyces cerevisiae is a protein phosphatase that catalyzes the dephosphory-latio

279 Fcp1 is a protein phosphatase that facilitates transcription elong

280 (Cn) is a calcium-activated serine/threonine protein phosphatase that is broadly implicated in divers

281 dc55) is a highly conserved serine-threonine protein phosphatase that is involved in diverse cellular

282 hosphatase 2 (AtSLP2) is a bona fide Ser/Thr protein phosphatase that is targeted to the mitochondria

283 on CFTR dephosphorylation by calcineurin, a protein phosphatase that is upregulated by CS.

284 m- and calmodulin-dependent serine/threonine protein phosphatase that plays a role in a wide range of

285 osine phosphatase (STEP) is a brain-specific protein phosphatase that regulates a variety of synaptic

286 PP2A is an essential protein phosphatase that regulates most cellular process

287 In this study, we focused on the five protein phosphatases that are predicted to be membrane-a

288 protein function, but equally important are protein phosphatases that balance their actions, their c

289 y establish a functional precedent for CDC25 protein phosphatases that lies outside of their canonica

290 report the development of a light-activated protein phosphatase, the dual specificity phosphatase 6

291 ofiles across all tissues, including type 2C protein phosphatases, the LATE EMBRYOGENESIS ABUNDANT PR

292 ancy pathways converge at clade A of type 2C protein phosphatases.The DOG1 protein is a major regulat

293 ia it is the sole annotated serine threonine protein phosphatase to counter the activity of multiple

294 tly reported that EYA1 functions as a unique protein phosphatase to dephosphorylate Myc at pT58 to re

295 Small Auxin Up RNA (SAUR) proteins regulate protein phosphatases to control H(+)-ATPase activity.

296 -specific SIRT inhibition; and activation of protein phosphatase type-2C.

297 The serine/threonine protein phosphatases type 2A (PP2A) are implicated in se

298 ligase Parkin, the cochaperone Bag6, and the protein phosphatase UBLCP1-stimulated peptide hydrolysis

299 ations is suppressed by inactivation of PhpP protein phosphatase, which concomitantly restores protei

300 PGAM5 is a mitochondrial protein phosphatase whose genetic ablation in mice resul