ライフサイエンスコーパス: protein-serine-threonine kinase

1 mbrane-spanning domain, and an intracellular protein-serine/threonine kinase.

2 through phosphorylation at Ser133 by various protein serine/threonine kinases.

3 s to consensus amino acid sequences of human protein-serine/threonine kinases.

4 richment of GO terms protein kinase activity/protein serine threonine kinase activity, response to he

5 ogical pathways, including the regulation of protein serine/threonine kinase activity.

6 se (PI3-kinase) and the PI3-kinase-dependent protein serine/threonine kinase Akt.

7 The protein serine/threonine kinase Akt/protein kinase B has

8 some of its downstream targets, such as the protein-serine/threonine kinases Akt and p70 S6 kinase (

9 The roles of the protein-serine/threonine kinase, Akt1, in signaling path

10 tains the conserved subdomains common to all protein-serine/threonine kinases and three "kinase inser

11 f the ataxia telangiectasia and Rad3-related protein serine/threonine kinase (ATR; also known as FRAP

12 intracellular signaling mechanism whereby a protein serine-threonine kinase (CaMKIV) is regulated by

13 Human prk encodes a novel protein serine/threonine kinase capable of strongly phos

14 Akt2 encodes a protein-serine/threonine kinase containing a pleckstrin

15 The AKT2 oncogene encodes a protein-serine/threonine kinase containing a pleckstrin

16 e products of at least three genes: fused (a protein-serine/threonine kinase), cubitus interruptus (a

17 ein possessing two GEF domains, as well as a protein serine/threonine kinase domain, and trio-like ge

18 significant homology with previously cloned protein serine/threonine kinase encoding genes Ip11 from

19 ne named BTAK, encoding a putative member of protein serine/threonine kinase family localized on chro

20 cancers, is a member of the conserved Aurora protein serine/threonine kinase family that is implicate

21 DMPK belongs to a novel protein serine/threonine kinase family, but its regulati

22 eins comigrated with the membrane-associated protein-serine/threonine kinase from S. solfataricus, wh

23 Mutations of the BRAF protein serine/threonine kinase gene have recently been

24 Raf-1 protein serine/threonine kinase has been implicated in g

25 Whereas the protein serine-threonine kinases have been well studied

26 Among the protein serine/threonine kinases identified to date, the

27 -6 gene and find that it encodes a predicted protein-serine/threonine kinase in the casein kinase 1 f

28 k activity), staurosporine (a broad-spectrum protein serine-threonine kinase inhibitor), PD98059 (an

29 prk encodes a protein serine/threonine kinase involved in regulating M

30 g to the activation of the mitogen-activated protein serine/threonine kinases JNK, p38, PKC and ERK,

31 The protein serine/threonine kinase, Mps1, is a critical com

32 me domains: two functional GEF domains and a protein serine/threonine kinase (PSK) domain.

33 Pioneering work on bacterial protein serine threonine kinases (PSTKs) has been perfor

34 previously identified a WD domain-containing protein, serine-threonine kinase receptor-associated pro

35 Pkn2 is a putative transmembrane protein serine/threonine kinase required for normal deve

36 tumour-suppressor SMAD proteins by receptor protein serine/threonine kinases (RS/TKs), leading to th

37 ogenitor kinase 1 (HPK1), a novel Ste20-like protein serine/threonine kinase, serves as an upstream m

38 We have cloned and characterized a putative protein serine/threonine kinase termed prk through a com

39 Bub1 is a protein serine-threonine kinase that plays multiple role

40 MEK kinase 2 (MEKK2) is a 70-kDa protein serine/threonine kinase that has been shown to f

41 in kinase (DNA-PKcs) is an enormous, 470-kDa protein serine/threonine kinase that has homology with m

42 multifunctional second messenger-independent protein serine/threonine kinase that phosphorylates many

43 sia mutated (ATM) is a high molecular weight protein serine/threonine kinase that plays a central rol

44 alpha (PKCalpha) is a phospholipid-dependent protein-serine/threonine kinase that plays a major role

45 AKT1/protein kinase Balpha is a protein-serine/threonine kinase that regulates multiple

46 nd WAG2 genes of Arabidopsis thaliana encode protein-serine/threonine kinases that are closely relate

47 ase domain of PR5K is related to a family of protein-serine/threonine kinases that are involved in th

48 ar putative CRDs are present in a variety of protein serine-threonine kinases, the data suggest that

49 n this study, we examine the STE20 family of protein serine-threonine kinases to investigate basic me

50 The Tpl-2 protein serine/threonine kinase was originally identifie

51 af family proto-oncogenes encode cytoplasmic protein serine/threonine kinases which play a critical r

52 d in this screen, designated MNK1, encodes a protein-serine/threonine kinase, which is most similar t

53 PK3 and PsPK5 genes of the garden pea encode protein-serine/threonine kinases whose catalytic domains

54 a mitogen-activated protein kinase-regulated protein serine-threonine kinase with a novel substrate s

55 WNK1 (with no lysine (K) 1) is a protein-serine/threonine kinase with a unique catalytic