ライフサイエンスコーパス: prothymosin

1 We identified Thymosin B4 (TMSB4) and Prothymosin a (PTMA) as main paracrine factors released

2 ic, high-mobility group-like nuclear protein prothymosin alpha (ProT(alpha)) and the transcriptional

3 his study, we investigate how BETT regulates prothymosin alpha (ProT), a nuclear protein previously s

4 have shown the strong anti-HIV-1 activity of prothymosin alpha (ProTalpha) derived from CD8(+) T cell

5 ve shown that EBNA3C interacts with p300 and prothymosin alpha (ProTalpha) in EBV-infected cells and

6 Prothymosin alpha (ProTalpha), a cellular molecule known

7 critical for immortalization interacts with prothymosin alpha (ProTalpha), a cellular protein previo

8 In this study we report that prothymosin alpha (ProTalpha), a protein found in the ce

9 t mRNAs complexing with HuR is that encoding prothymosin alpha (ProTalpha), an inhibitor of the apopt

10 and its highly negatively charged chaperone, prothymosin alpha (ProTalpha).

11 Prothymosin alpha (PTalpha) is a small highly acidic pro

12 We find that prothymosin alpha (PTalpha) selectively enhances transcr

13 ogenetic factors thymosin beta-4 (TMSB4) and prothymosin alpha (PTMA).

14 direct relationship between the function of prothymosin alpha and the phosphorylation of eEF-2.

15 the negatively charged and fully disordered prothymosin alpha and the positively charged and folded

16 Our results identify prothymosin alpha as a host factor that restricts HIV-1

17 ecently, Vega et al. proposed that exogenous prothymosin alpha can specifically increase the phosphor

18 Human and monkey prothymosin alpha contain activated carbonyl groups on g

19 r laboratory has recently shown that primate prothymosin alpha contains stoichiometric amounts of pho

20 1) Prothymosin alpha continued to be metabolically labeled

21 dride showed that: 1) phosphate recovered on prothymosin alpha decreased 8-fold when lysates were tre

22 protein, and a histidine-tagged recombinant prothymosin alpha expressed either in bacteria or in COS

23 Overexpression of prothymosin alpha in vitro confirmed that this cellular

24 mine the half-life of the acyl phosphates on prothymosin alpha in vivo by pulse-labeling HeLa cells w

25 Our data suggest that the "activity" of prothymosin alpha involves the turnover of its acyl phos

26 Prothymosin alpha is a small, acidic, essential nuclear

27 Prothymosin alpha is a small, highly acidic, abundant, n

28 Our data demonstrate that prothymosin alpha is energy-rich by virtue of stoichiome

29 The ability of cells to phosphorylate old prothymosin alpha molecules was established by demonstra

30 curves of metabolically labeled native [32P]prothymosin alpha or a [32P]histidine-tagged variant res

31 ely charged and disordered histone chaperone prothymosin alpha to efficiently invade the H1-nucleosom

32 Our data indicate that most of prothymosin alpha's phosphates are subject instantaneous

33 ystem biology analysis identified ProTalpha (prothymosin alpha) as a protein associated with RHVD.

34 hemistry for one of the identified proteins, prothymosin alpha, demonstrated prominent nuclear staini

35 n, and sonication) and three preparations of prothymosin alpha, one of which was purified by gentle m

36 .0 and its chaperone, the negatively charged prothymosin alpha.

37 lmodulin, and calcium was also unaffected by prothymosin alpha.

38 he sole site of phosphate in purified bovine prothymosin alpha.

39 h expression of the gene PTMA, which encodes prothymosin alpha.

40 RT-PCR, as well as immunohistochemistry for prothymosin alpha.

41 R-associated proteins (PHAP) and oncoprotein prothymosin-alpha (ProT).

42 Prothymosin-alpha (ProTalpha), a small acidic protein pr

43 ity purification we recently discovered that prothymosin-alpha (ProTalpha), a small highly acidic pro

44 in zero, mitogen-activated protein kinase 3, prothymosin beta 4, and brain lipid-binding protein.

45 enes ornithine decarboxylase (ODC) and alpha prothymosin (pT).