ライフサイエンスコーパス: pseudorabies virus

1 ique long region similar to that observed in pseudorabies virus.

2 ase of infection in Vero cells infected with pseudorabies virus.

3 c recombinant strains (PRV-152 and BaBlu) of pseudorabies virus.

4 sport of two recombinant isogenic strains of pseudorabies virus.

5 o infections by unrelated pathogens, such as pseudorabies virus.

6 scles, were injected with Bartha's strain of pseudorabies virus.

7 to infer the proximity of several strains of pseudorabies virus.

8 hed from studies of herpes simplex virus and pseudorabies virus.

9 imilar to the phenotype previously shown for pseudorabies virus.

10 g after inoculation of the stomach wall with pseudorabies virus 152, a viral label that reports enhan

11 rebral injections of an attenuated strain of pseudorabies virus, a neurotropic alpha herpesvirus that

12 s in the spinal cord, was characterized with pseudorabies virus, a retrograde transynaptic tracer.

13 Using pseudorabies virus, a transsynaptic tracer, in anestheti

14 e poliovirus, herpesvirus, rabies virus, and pseudorabies virus all utilize neuronal retrograde trans

15 Pseudorabies virus, an alpha-herpesvirus, is capable of

16 tructure of the N-terminal half of UL37 from pseudorabies virus, an alphaherpesvirus closely related

17 following infection with the closely related pseudorabies virus and observed similar perimeters of gl

18 ynaptically labeled from the distal colon by pseudorabies virus and several of these were also retrog

19 a subunit, Fluoro-Gold, the Bartha strain of pseudorabies virus, and biotinylated dextran amine.

20 simplex virus types 1 and 2 (HSV-1 and -2), pseudorabies virus, and bovine herpesvirus 1.

21 phaherpesviruses herpes simplex virus (HSV), pseudorabies virus, and bovine herpesvirus type 1.

22 ctures of gH/gL from herpes simplex virus 2, pseudorabies virus, and Epstein-Barr virus revealed dist

23 Cytomegalovirus, pseudorabies virus, and Sindbis virus all evoked a 2-log

24 ilar mutant of the related alphaherpesvirus, pseudorabies virus, and suggests that the glycoprotein r

25 lycoproteins of herpes simplex virus type 1, pseudorabies virus, and varicella-zoster virus, BHV-1 gI

26 fork movement in vivo during replication of pseudorabies virus, another herpesvirus.

27 The glycoproteins I and E of pseudorabies virus are important mediators of cell-to-ce

28 s simplex virus, varicella zoster virus, and pseudorabies virus are neurotropic pathogens of the Alph

29 Using pseudorabies virus as a model, we infected neuron cell b

30 In this report, we have used pseudorabies virus as a neuroanatomical tract tracer in

31 Here, using herpes simplex virus type I and pseudorabies virus as model alphaherpesviruses, we show

32 ame animals by injection of a recombinant of pseudorabies virus Bartha (PRV) into the contralateral v

33 he transsynaptic retrograde transport of the pseudorabies virus Bartha (PRV-Bartha) strain has become

34 Pseudorabies virus, Bartha's K strain, was injected into

35 ry associated with the hippocampus using the pseudorabies virus-Bartha strain (PRV-Bartha) tracer in

36 virus 1 (EHV-1), varicella-zoster virus, and pseudorabies virus, but very little is known about the p

37 pesviruses, such as herpes simplex virus and pseudorabies virus, cause a broad range of diseases in h

38 labeling of the phrenic motoneuron pool with pseudorabies virus demonstrated a substantial number of

39 Pseudorabies virus encodes a membrane protein (Us9) that

40 ine herpesvirus 1, equine herpesvirus 4, and pseudorabies virus, establish a quiescent/latent infecti

41 By using pseudorabies virus expressing green fluorescence protein

42 rions, epithelial cells infected by HSV-1 or pseudorabies virus following ADS express fewer than two

43 milarities and differences between HSV-1 and pseudorabies virus gE.

44 icial chromosome (BAC) containing the 142-kb pseudorabies virus genome was constructed such that the

45 d using green fluorescent protein expressing pseudorabies virus (GFP-PRV) to (1) characterize age-dep

46 sons with homologous HSV-2 gH/gL and partial pseudorabies virus gH structures support the domain boun

47 Recently, a pseudorabies virus glycoprotein D (gD)-green fluorescent

48 The Bartha strain of pseudorabies virus has several recognized mutations, inc

49 naptic labeling from the adrenal gland using pseudorabies virus identified presympathetic GABAergic n

50 ficking, we analyzed the axonal transport of pseudorabies virus in the presence and absence of pUS9.

51 tween HSV1 and the related alphaherpesvirus, pseudorabies virus, in which the homologues of all three

52 al afferent pathways can be identified after pseudorabies virus infection of the kidney.

53 sitive neurones in the LH were labelled with pseudorabies virus injected into the liver of parasympat

54 erebral cortex were identified in rats after pseudorabies virus injections were made in functionally

55 Pseudorabies virus inoculated into the distal femoral me

56 Injection of pseudorabies virus into different regions of the MD or r

57 nsneuronally infected following injection of pseudorabies virus into rectus abdominis or transversus

58 injected the retrograde transynaptic tracer pseudorabies virus into single tensor tympani (TT) muscl

59 Injection of conditional pseudorabies virus into the brain of an LHRH::CRE mouse

60 By injecting pseudorabies virus into the diaphragm and using c-Fos ac

61 injected a retrograde-specific strain of the pseudorabies virus into the rat OB and piriform cortex.

62 Fluorogold or green fluorescent pseudorabies virus labeled postganglionic neurons in the

63 We used transsynaptic anterograde pseudorabies virus labeling of fungiform taste papillae

64 The stability of interneuronal pseudorabies virus labeling patterns following lateral c

65 Pseudorabies virus-labelled cells were also seen in the

66 and bladder body injections, the majority of pseudorabies virus-labelled cells were found in the late

67 Very few pseudorabies virus-labelled cells were found rostral to

68 resembles in many respects the phenotype of pseudorabies virus lacking glycoproteins gM, gE, and gI.

69 Mutant pseudorabies virus lacking U(L)3.5 is deficient in viral

70 demonstrate that the pUL31 component of the pseudorabies virus nuclear egress complex is a condition

71 remotor interneurons with the trans-synaptic pseudorabies virus PRV-152 revealed the presence of burs

72 re retrogradely labelled (prior injection of pseudorabies virus PRV-152) and whole-cell, patch clamp

73 A strain of pseudorabies virus (PRV 152) isogenic with the Bartha st

74 itreal injection of the attenuated strain of pseudorabies virus (PRV Bartha) results in transneuronal

75 ntraocular injection of the Bartha strain of pseudorabies virus (PRV Bartha) results in transsynaptic

76 rus (HSV), varicella-zoster virus (VZV), and pseudorabies virus (PRV) all utilize a complex of two gl

77 well as for the animal herpesviruses porcine pseudorabies virus (PRV) and bovine herpesvirus 1 (BHV-1

78 entified by immunohistochemical detection of pseudorabies virus (PRV) and corticotropin-releasing fac

79 ative to the model alphaherpesvirus pathogen pseudorabies virus (PRV) and demonstrate that this criti

80 are the most widely used method to visualize pseudorabies virus (PRV) and herpes simplex virus (HSV)

81 he gD glycoprotein of the alphaherpesviruses pseudorabies virus (PRV) and herpes simplex virus 2 (HSV

82 Pseudorabies virus (PRV) and herpes simplex virus type 1

83 9p and the glycoprotein heterodimer gE/gI of pseudorabies virus (PRV) and herpes simplex virus type 1

84 Both Pseudorabies virus (PRV) and human Herpes simplex virus

85 3 in herpes simplex virus type 1 (HSV-1) and pseudorabies virus (PRV) and ORF66 in varicella-zoster v

86 ane proteins encoded by the alphaherpesvirus pseudorabies virus (PRV) are internalized after reaching

87 The membrane proteins gI and gE of Pseudorabies virus (PRV) are required for viral invasion

88 Using pseudorabies virus (PRV) as model virus, we performed ch

89 The structure of pseudorabies virus (PRV) capsids isolated from the nucle

90 the viral transcriptional activator, VP16 on pseudorabies virus (PRV) escape from genome silencing.

91 The alphaherpesvirus pseudorabies virus (PrV) establishes latency primarily i

92 Like other alphaherpesviruses, pseudorabies virus (PrV) exhibits restricted gene expres

93 d PSPMNs by using recombinant strains of the pseudorabies virus (PRV) for trans-synaptic tract tracin

94 d PSPMNs by using recombinant strains of the pseudorabies virus (PRV) for transsynaptic tract-tracing

95 pothesis, we used recombinant strains of the pseudorabies virus (PRV) for transsynaptic tract-tracing

96 rograde transport of an attenuated strain of pseudorabies virus (PRV) from the nucleus accumbens was

97 endent retrograde transneuronal transport of pseudorabies virus (PRV) from the stomach wall.

98 determine the role of internalization of the pseudorabies virus (PRV) gE and gI proteins, we construc

99 The pseudorabies virus (PRV) gE gene encodes a multifunction

100 A full-length clone of the 142-kb pseudorabies virus (PRV) genome was constructed as a sta

101 nabled the escape from silencing of incoming pseudorabies virus (PRV) genomes.

102 Pseudorabies virus (PRV) glycoprotein E (gE) is a type I

103 ynaptic tracing with peripheral injection of pseudorabies virus (PRV) has been extensively characteri

104 K in herpes simplex virus type 1 (HSV-1) and pseudorabies virus (PRV) have been well studied.

105 using transneuronal retrograde transport of pseudorabies virus (PRV) in normal animals and in animal

106 ction of the transneuronal retrograde tracer pseudorabies virus (PRV) in rats, we previously localize

107 s, was mapped using the transneuronal tracer pseudorabies virus (PRV) in the ferret.

108 esviruses herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV) in the infected cell cytoplasm

109 cellular virions and axonal assemblies after pseudorabies virus (PRV) infection of cultured neurons.

110 After pseudorabies virus (PRV) infection of murine L929 cells,

111 the host gene expression profile after acute pseudorabies virus (PRV) infection of the CNS using Affy

112 models of viral egress from neurons by using pseudorabies virus (PRV) infection of the rat retina: do

113 nal spread of herpes simplex virus (HSV) and pseudorabies virus (PRV) infection, a culture system con

114 nduced after herpes simplex virus type 1 and pseudorabies virus (PRV) infections of rat embryonic fib

115 When the swine alphaherpesvirus pseudorabies virus (PRV) infects the rat retina, it repl

116 ed by retrograde trans-synaptic migration of pseudorabies virus (PRV) injected into the adrenal gland

117 Using the retrograde, transsynaptic tracer pseudorabies virus (PRV) injected into the BAT of mice,

118 astric nerves transected, were infected with pseudorabies virus (PRV) injected into the external uret

119 ia the transsynaptic retrograde transport of pseudorabies virus (PRV) injected into the kidneys of ra

120 ted neurons in the preoptic region following pseudorabies virus (PRV) injections into either the supe

121 Pseudorabies virus (PRV) injections were made into the l

122 sneuronal tracing studies using injection of pseudorabies virus (PRV) into either the diaphragm or re

123 studied after injecting the Bartha strain of pseudorabies virus (PRV) into the sciatic nerve to provi

124 epithelial cells, alphaherpesviruses such as pseudorabies virus (PRV) invade axons of peripheral nerv

125 Pseudorabies virus (PRV) is a broad host range, swine al

126 Transneuronal spread of pseudorabies virus (PRV) is a multistep process that req

127 Pseudorabies virus (PRV) is a porcine alphaherpesvirus t

128 Pseudorabies virus (PRV) is a useful tracer that is retr

129 mal degradation of KIF1A in axons.IMPORTANCE Pseudorabies virus (PRV) is an alphaherpesvirus related

130 Pseudorabies virus (PRV) is an alphaherpesvirus related

131 Glycoprotein E (gE) gene of pseudorabies virus (PRV) is conserved among diverse alph

132 The alphaherpesvirus pseudorabies virus (PRV) is the causative agent of pseud

133 Pseudorabies virus (PRV) mutants lacking the Us9 gene ca

134 Retrograde infection by pseudorabies virus (PRV) of neuronal populations neighbo

135 by inoculating the ventral stomach wall with pseudorabies virus (PRV) on postnatal day 1 (P1), P4, or

136 simplex virus (HSV) entry activity, but not pseudorabies virus (PRV) or bovine herpesvirus 1 (BHV-1)

137 d the retrograde transneuronal tracer Bartha-pseudorabies virus (PRV) or the retrograde marker choler

138 ane protein present in the lipid envelope of pseudorabies virus (PRV) particles in a unique tail-anch

139 Toward this end, we generated a novel pseudorabies virus (PrV) recombinant in which a 282-bp r

140 In this report, we describe construction of pseudorabies virus (PRV) recombinants that efficiently e

141 escape from latency by the alphaherpesvirus pseudorabies virus (PRV) relies on a structural viral te

142 ial cells infected with the alphaherpesvirus pseudorabies virus (PRV) results in activation of the ha

143 Here, we refine this map using pseudorabies virus (PRV) retrograde tracing, indicating

144 Notably, retrograde tracing using pseudorabies virus (PRV) revealed that both dorsal and v

145 rted methods we solved the structures of (i) Pseudorabies virus (PRV) RNA G-quadruplex and ligand com

146 stem, we have discovered a novel role of the pseudorabies virus (PRV) serine/threonine kinase US3 in

147 The attenuated pseudorabies virus (PRV) strain Bartha contains several

148 After intraocular injection of the virulent pseudorabies virus (PRV) strain Becker into late-stage c

149 To accomplish this, we have constructed pseudorabies virus (PRV) strains in which viral propagat

150 , but partial deletions generated in HSV and pseudorabies virus (PrV) suggest an additional function

151 egulates interferon (IFN) induction and that pseudorabies virus (PRV) targets PRDX1 to evade IFN indu

152 axonally delivered genomes is facilitated by pseudorabies virus (PRV) tegument proteins.

153 ly(A) fraction of the lytic transcriptome of pseudorabies virus (PRV) throughout a 12-hour interval o

154 This study used the transneuronal tracer pseudorabies virus (PRV) to investigate the CNS network

155 ns were identified by immunogold labeling of pseudorabies virus (PRV) transported retrogradely and tr

156 UL13 protein kinase of the alphaherpesvirus pseudorabies virus (PRV) triggers phosphorylation of FTO

157 The subcellular distribution of the pseudorabies virus (PRV) UL28 protein was examined by in

158 The pseudorabies virus (PRV) UL54 homologs are important mul

159 We demonstrate here that the pseudorabies virus (PRV) Us2 protein is synthesized earl

160 The pseudorabies virus (PRV) Us3 gene is conserved among the

161 The protein product of the pseudorabies virus (PRV) Us9 gene is a phosphorylated, t

162 Pseudorabies virus (PRV) Us9 is a small, tail-anchored (

163 In this report, we demonstrate that the pseudorabies virus (PRV) Us9 protein is present in infec

164 s simplex virus (HSV) and, as reported here, pseudorabies virus (PRV) utilize the ESCRT apparatus to

165 nal sorting and transport of fully assembled pseudorabies virus (PRV) virions is dependent on the vir

166 e provide an initial characterization of the pseudorabies virus (PRV) VP22 homologue.

167 ingly, entry of the porcine alphaherpesvirus pseudorabies virus (PRV) was inhibited by sphingomyelin-

168 Pseudorabies virus (PRV) was injected into the pancreas

169 tracing experiments were performed in which pseudorabies virus (PRV) was injected into the stellate

170 riments, the retrograde transneuronal tracer pseudorabies virus (PRV) was microinjected into the CEAm

171 A replication-competent gL-null pseudorabies virus (PrV) was shown to express a gDgH hyb

172 ade tract tracing, using isogenic strains of pseudorabies virus (PRV) with distinct fluorescent repor

173 dies, we compared gH of the alphaherpesvirus pseudorabies virus (PrV) with gH of the gammaherpesvirus

174 Pseudorabies virus (PRV), a broad host range alphaherpes

175 Pseudorabies virus (PRV), a member of the Alphaherpesvir

176 Pseudorabies virus (PRV), a neurotropic swine alpha herp

177 brane glycoproteins gE and gI are encoded by pseudorabies virus (PRV), a neurotropic, broad-host-rang

178 lenic function was accomplished by injecting pseudorabies virus (PRV), a retrograde transynaptic trac

179 that the amino-terminal one-third of gC from pseudorabies virus (PRV), a swine herpesvirus, includes

180 Pseudorabies virus (PRV), a swine neurotropic alphaherpe

181 g vesicular stomatitis (VSV), Sindbis virus, pseudorabies virus (PRV), adeno-associated virus (AAV),

182 Using pseudorabies virus (PRV), an alphaherpesvirus capable of

183 Pseudorabies virus (PRV), an alphaherpesvirus related to

184 Previous studies showed that proteins from pseudorabies virus (PRV), an alphaherpesvirus, localize

185 work reports that the UL13 protein kinase of pseudorabies virus (PRV), an alphaherpesvirus, mediates

186 erpes simplex viruses (HSV) 1 and 2, porcine pseudorabies virus (PRV), and bovine herpesvirus 1 (BHV-

187 (BHV-1), equine herpesvirus type 1 (EHV-1), pseudorabies virus (PRV), and varicella-zoster virus (VZ

188 pesviruses, such as herpes simplex virus and pseudorabies virus (PRV), are neuroinvasive dsDNA viruse

189 Alphaherpesviruses, including pseudorabies virus (PRV), are neuroinvasive pathogens th

190 including herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), are pathogens of the nervous s

191 U(S)11c119.3 cells are fully susceptible to pseudorabies virus (PRV), as shown by single-step growth

192 The related animal herpesvirus, pseudorabies virus (PRV), encodes a homologous set of gl

193 sviruses, herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), have suggested that UL37 plays

194 pes viruses: herpes simplex virus (HSV1) and pseudorabies virus (PrV), human immunodeficiency virus t

195 peroxidase conjugated to colloidal gold, or pseudorabies virus (PRV), into the nuclear core of the r

196 st commonly varicella-zoster virus (VZV) and pseudorabies virus (PRV), may cause cranial nerve disord

197 In the swine pathogen pseudorabies virus (PRV), mutant viruses with internal d

198 ls also showed enhanced fusion activity with pseudorabies virus (PRV), paramyxovirus, and rhabdovirus

199 Alphaherpesviruses, including pseudorabies virus (PRV), spread directionally within th

200 Live attenuated vaccine strains of pseudorabies virus (PRV), such as PRV Bartha, are among

201 lex virus 1 (HSV-1), HSV-2, and veterinarian pseudorabies virus (PRV), that infect the peripheral ner

202 In pseudorabies virus (PRV), the Us9 protein is a 98-amino-

203 ished retrograde transneuronal viral tracer, pseudorabies virus (PRV), was injected into the ventral

204 The transneuronal tracer, pseudorabies virus (PRV), was used to identify pathways

205 Using a viral transneuronal tract tracer, pseudorabies virus (PRV), we also tested whether the com

206 Using pseudorabies virus (PRV), we have previously shown that

207 Using the neuroinvasive herpesvirus, pseudorabies virus (PRV), we show that the viral protein

208 cle-specific injection of an mRFP-expressing pseudorabies virus (PRV), which acts as a transsynaptic

209 including herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), within neurons is poorly under

210 Pseudorabies virus (PRV)-a retrograde transneuronal trac

211 s study were to identify the mechanism(s) of pseudorabies virus (PrV)-induced down-regulation of porc

212 nervous system, alphaherpesviruses-including pseudorabies virus (PRV)-use retrograde axonal transport

213 tion with virulent and attenuated strains of pseudorabies virus (PRV).

214 athways in rats using recombinant strains of pseudorabies virus (PRV).

215 te entry of herpes simplex viruses (HSV) and pseudorabies virus (PRV).

216 of gD (for example, HSV-1/Rid), and porcine pseudorabies virus (PRV).

217 following infection of the left kidney with pseudorabies virus (PRV).

218 a receptor for the porcine alphaherpesvirus pseudorabies virus (PRV).

219 es, such as herpes simplex virus 1 (HSV1) or pseudorabies virus (PRV).

220 el to study neuronal spread and virulence of pseudorabies virus (PRV).

221 -1), HSV-2, and the related alphaherpesvirus pseudorabies virus (PRV).

222 an alpha-herpes virus, the Bartha strain of pseudorabies virus (PRV).

223 DMV neurons projecting to the stomach using pseudorabies virus (PRV).

224 DA), and retrograde tracing with fluorescent pseudorabies virus (PRV).

225 onserved in varicella-zoster virus (VZV) and pseudorabies virus (PRV).

226 of two neurotropic herpesviruses: HSV-1 and pseudorabies virus (PRV).

227 emale Sprague-Dawley rats were infected with pseudorabies virus (PRV, Bartha's K-strain) by injection

228 nstructing a replication-competent strain of pseudorabies virus (PRV-263) that changes the profile of

229 were transsynaptically labeled by injecting pseudorabies virus (PRV-614) into the kidney, indicating

230 train of the retrograde transneuronal tracer pseudorabies virus (PRV-Ba) was injected into rat choroi

231 e transneuronal tracer, the Bartha strain of pseudorabies virus (PRV-Ba), were injected into the uppe

232 tract tracing using an attenuated strain of pseudorabies virus (PRV-Bartha) was combined with immuno

233 hway with those of other alphaherpesviruses (pseudorabies virus [PRV] and herpes simplex virus 1 [HSV

234 ions of the SCN using the swine herpesvirus (pseudorabies virus, PRV) as a tool for transynaptic anal

235 S-specific transneuronal viral tract tracer, pseudorabies virus (PRV152) and demonstrated the sensory

236 , to identify GG premotoneurons, we injected pseudorabies virus (PRV152) into the GG muscle.

237 n tracing using a sympathetic nerve-specific pseudorabies virus, PRV152.

238 ed fluorophore expression from a recombinant pseudorabies virus (PRV263) carrying a Brainbow cassette

239 tructed a panel of Cre recombinase-activated pseudorabies viruses (PRVs) that enabled retrograde trac

240 Specifically, we injected the conditional pseudorabies virus recombinant (BA2001) that can replica

241 Dual-labeling studies with pseudorabies virus recombinants also showed prephrenic i

242 The first method uses HSV-1 and pseudorabies virus recombinants that express one of thre

243 Combined with pseudorabies virus retrograde tracing from the iWAT, we

244 ransneuronal retrograde pathway tracing with pseudorabies virus revealed connectivity between MnPO VG

245 We constructed a pseudorabies virus strain that expressed Us9-GFP and tes

246 liver and epididymal white fat in mice using pseudorabies virus strains expressing different reporter

247 Two immunohistochemically distinct pseudorabies virus strains were injected into male Sprag

248 omplemented prior herpes simplex virus 1 and pseudorabies virus studies investigating two other inhib

249 riments with ICP4 homologs revealed that the pseudorabies virus TAD is a potent activator of the gD p

250 Despite being a major component of the pseudorabies virus tegument, VP22 is not required for PR

251 We report the development of a pseudorabies virus that can be used for retrograde traci

252 Starting with derivatives of pseudorabies virus that encode a fluorescent protein fus

253 ell imaging, we made a series of recombinant pseudorabies viruses that encoded green fluorescent prot

254 Here, the spread of pseudorabies virus through renal sensory pathways was ex

255 vulgaris leucoagglutinin (anterograde), and pseudorabies virus (transneuronal retrograde) tract-trac

256 n subunit b retrograde tracing from rRPa and pseudorabies virus transynaptic retrograde tracing from

257 The large DNA viruses, herpes simplex and pseudorabies viruses, use ubiquitous nectins 1 and 2.

258 The resistance to pseudorabies virus was CD4(+) T cell dependent, because

259 Pseudorabies virus was injected into the wall of the ven

260 pathway, a retrograde transsynaptic tracer (pseudorabies virus) was injected into the orbicularis oc

261 r the retrograde transneuronal viral tracer, pseudorabies virus, was injected into the stellate sympa

262 an infectious clone of the alphaherpesvirus pseudorabies virus, we have made a collection of truncat

263 paring HSV-1 to a related alpha herpesvirus, pseudorabies virus, we show that this preferential exocy

264 ntral nervous system neurons infected with a pseudorabies virus were examined in vitro by using whole

265 /Cas9 and Cre/Lox system against re-emerging Pseudorabies virus, which caused the recent devastating