ライフサイエンスコーパス: pulsatility

1 reproduces femoral artery flow waveforms and pulsatility.

2 ctrochemical analysis system to determine LH pulsatility.

3 increased +18+/-2% (P:<0.0001) with enhanced pulsatility.

4 osine-coronary flow response curve at higher pulsatility.

5 ly during the late diastolic phase with less pulsatility.

6 analyze serial LH measurements to assess LH pulsatility.

7 and 4D flow MRI to assess cerebral arterial pulsatility.

8 ervals (e.g., 10 minutely) to assess GnRH/LH pulsatility.

9 ents with increased luteinizing hormone (LH) pulsatility.

10 the effect of age and sex on blood flow and pulsatility.

11 glymphatic clearance by regulating arterial pulsatility.

12 halorhodopsin were found to reset ongoing LH pulsatility.

13 hite matter integrity or brain microvascular pulsatility.

14 ith archaerhodopsin for 30 min suppressed LH pulsatility.

15 rmful effects of excessive pressure and flow pulsatility.

16 9 versus 0.48 mm Hg/mL; P<0.001), greater LA pulsatility (19 versus 13 mm Hg; P<0.001), and higher wa

17 n 3% and 7%), leukocyte speed 14% lower, and pulsatility 25% higher, but none of these differences wa

18 n microscopy revealed that cerebral arterial pulsatility, a major driver of the glymphatic system, wa

19 locities, velocity time integral, resistive, pulsatility, acceleration indices (RI, PI, AI), and flow

20 ers as activated by static pressure, whereas pulsatility activated extracellular Na(+)-dependent Cl(-

21 ronary vasculature encounters a reduction in pulsatility after implementing durable continuous-flow l

22 entricular systolic load; excessive pressure pulsatility also decreases diastolic pressure, necessary

23 e performance of the widely employed hormone pulsatility analysis program Cluster.

24 ugh residual myocardial function to maintain pulsatility and aortic root ejection and to maintain, wi

25 Restoring pulsatility and decreasing left ventricular afterload wi

26 Increased aortic pressure wave pulsatility and greater decrease in pulsatility on treat

27 ith ghrelin's property as an amplifier of GH pulsatility and its speculated role in establishing an i

28 l cushioning function, which limits arterial pulsatility and protects the microvasculature from poten

29 ic and mean blood flow velocities as well as pulsatility and resistance (RI) indices were measured.

30 were impaired in CHD women (umbilical artery pulsatility and resistance index at 32 weeks in CHD vers

31 Pulsatility and resistance indexes and cerebral oxygen e

32 were found in cerebral blood velocities and pulsatility and resistance indexes in the overall popula

33 ues that are caused by cardiac motion, blood pulsatility, and any muscle activity.

34 duct, blood plasma volume fraction, vascular pulsatility, and CVR (in response to CO(2)) scans.

35 permeability surface area product), vascular pulsatility, and decreased cerebrovascular reactivity (C

36 The magnitude, pulsatility, and directional characteristics of FSS are

37 f estrogen, lacks other ovarian hormones and pulsatility, and is not responsive to feedback regulatio

38 gh PS would be associated with high arterial pulsatility, and that links to cognition would be specif

39 ents had a significant effect on venous flow pulsatility, and the ratio of respiration-dependent to t

40 rmal aortic stiffness and increased pressure pulsatility are associated with blunted microvascular re

41 ile (ultradian), the genomic effects of this pulsatility are poorly understood.

42 Vascular stiffness and blood pressure pulsatility are related; however, temporal relationships

43 campus, and provide no evidence of excessive pulsatility as a trigger of BBB disruption.

44 B leakage is triggered by excessive vascular pulsatility, as suggested by animal studies, remains unk

45 as well as LH responses to kisspeptin and LH pulsatility, as surrogate marker of GnRH secretion.

46 sed to regulate real-time physiological flow pulsatility at constant mean pressure.

47 sociation with greater beat-to-beat cerebral pulsatility (average DeltaMCA-PI vs HR/DBP/SBP unadjuste

48 Luteinizing hormone (LH) pulsatility, body weight, ovarian variables, and hormone

49 Sildenafil did not reduce pulsatility but increased cerebrovascular reactivity and

50 t thrombus growth rate is enhanced by modest pulsatility but less so when pulsations are amplified in

51 ee measures of aortic stiffness and pressure pulsatility (carotid-femoral pulse wave velocity, centra

52 herapy displayed higher aortic pressure wave pulsatility (central pulse pressure [PP], reflected pres

53 is a highly accurate method to detect brain pulsatility changes related to cerebrovascular functioni

54 ease in lean and obese subjects with similar pulsatility characteristics.

55 ts also suggest that energy-based indices of pulsatility combining pressure and flow data are more se

56 s and mechanisms of pH(i) modulation by flow pulsatility, comparing pressurized steady versus pulse-f

57 Because high pulsatility could represent prodromal cerebrovascular ch

58 ncreased aortic stiffness and excessive flow pulsatility damage the microcirculation, leading to quan

59 measures of vascular stiffness and pressure pulsatility derived from arterial tonometry (carotid-fem

60 ect linear models) on middle cerebral artery pulsatility, derived from peak systolic and end-diastoli

61 ication of mean flow by adenosine and higher pulsatility, despite being administered at doses matchin

62 Increasing pulsatility elevated mean coronary flow +11.5 +/- 1.7 %

63 Pulsatility emerges at intermediate dissociation rates,

64 trategies to provide some degree of arterial pulsatility, even in continuous flow LVADs may be necess

65 f MyoII dynamics that underlie stability and pulsatility: exchange kinetics governed by phosphorylati

66 Reduced pulsatility has been implicated as a contributing cause.

67 We used tissue pulsatility imaging (TPI), a novel ultrasound (US) neuro

68 state fMRI, and BTP, using ultrasound Tissue Pulsatility Imaging, were compared before and rapidly af

69 In a separate pilot study we compared leptin pulsatility in 414 plasma samples collected every 7 minu

70 how that these parameters can distinguish LH pulsatility in different clinical contexts including in

71 Reduced pulsatility in patients supported with the continuous-fl

72 Low HR is associated with greater cerebral pulsatility in patients with SVD, potentially mediated b

73 lained most variance in CADASIL and arterial pulsatility in sporadic SVD, but similar main variance s

74 trogen to restrain kisspeptin (KISS1)-neuron pulsatility in the arcuate hypothalamic nucleus, while a

75 dysfunction, related in some part to lack of pulsatility in the pulmonary circulation because of alte

76 investigate the mechanistic role of vascular pulsatility in this context.

77 Spectrum Analysis is applied to determine LH pulsatility in three distinct patient cohorts.

78 y serve as a regulator of endogenous insulin pulsatility in vivo.

79 Pulmonary artery pulsatility increased in two of three locations (main +2

80 heart rate STV (CTG STV), early DV changes (pulsatility index >95th percentile; DV p95), or late DV

81 Among hemodynamic parameters, an aortic pulsatility index <1.5 emerged as a robust predictor of

82 A low aortic pulsatility index (<1.5) and the cold/wet hemodynamic pr

83 3]; P = 0.016), and lower pulmonary arterial pulsatility index (1.66 [1.27-2.50] vs 2.52 [1.63-3.82];

84 index (2.4-2.8 L/[min.m2]), pulmonary artery pulsatility index (1.73-2.13), and right ventricle cardi

85 sus 82.2%, P<0.001), higher pulmonary artery pulsatility index (2.14 versus 1.51, P<0.01), lower card

86 een aortic stiffness and GFR was mediated by pulsatility index (95% confidence interval of indirect e

87 offered as mediators downstream from higher pulsatility index (95% confidence interval of indirect e

88 ysfunction, including lower pulmonary artery pulsatility index (beta, -0.23; SE, 0.01; P<0.001), high

89 ips between HR, blood pressure and Gosling's pulsatility index (MCA-PI) are reported as beta-coeffici

90 ac power output (CPO) and pulmonary arterial pulsatility index (PAPi) were measured at baseline and 2

91 The pulmonary artery pulsatility index (PAPi), calculated from the ratio of t

92 was evaluated by means of the LVAD parameter pulsatility index (PI) and by the echocardiographic asse

93 artery resistive index (RI), hepatic artery pulsatility index (PI) and hepatic artery flow volume.

94 lic velocity (EDV), resistive index (RI) and pulsatility index (PI) of ophthalmic artery (OA), poster

95 ad DVT and compared them with respect to the pulsatility index (PI) value of the popliteal artery.

96 Pulsatility index (PI) values of DA, RPA, LPA, and DPA w

97 Use of TTF probes to assess graft flow and pulsatility index (PI) values.

98 Tissue thicknesses and pulsatility index (PI) were analyzed with independent sa

99 High cerebral arterial pulsatility index (PI), white matter lesions (WMLs), enl

100 CD) on the middle cerebral artery (MCA): MCA pulsatility index (PIa) and an estimator based on diasto

101 lsatility was quantified by using the venous pulsatility index (VPI), the venous equivalent of resist

102 centile] and a high umbilical artery Doppler pulsatility index [>95th percentile]).

103 Carotid pulse pressure, pulsatility index and carotid-femoral pulse wave velocit

104 Our hypothesis is that the aortic pulsatility index and hemodynamic profiling utilizing in

105 s and/or kidneys in 12 healthy subjects, the pulsatility index and resistive index were estimated fro

106 Pulsatility index and resistive index were mapped with c

107 Uterine artery pulsatility index and serum placental growth factor and

108 Umbilical artery pulsatility index and uterine artery resistance index an

109 At 23 to 25 weeks, uterine artery pulsatility index correlated with serum soluble endoglin

110 k velocity in the LCCA (p = 0.04) and higher pulsatility index of both the RCCA and LCCA (p = 0.006 a

111 In contrast, the pulsatility index of the middle cerebral artery was a po

112 We used a higher umbilical/cerebral artery pulsatility index ratio as an indicator of preferential

113 with SCA also had lower resistive index and pulsatility index values compared with healthy controls

114 ablish reference intracranial blood flow and pulsatility index values in a large cross-sectional samp

115 /s) versus 29 cm/s (23-35 cm/s) (p = 0.004), pulsatility index was 1.10 (0.97-1.18) versus 0.94 (0.89

116 Pulsatility index was associated with lower memory score

117 Pulsatility index was associated with lower whole brain

118 Carotid flow pulsatility index was negatively related to the aorta-ca

119 showed lower blood flow velocity and higher pulsatility index within perforating arteries of the cen

120 The pulsatility index within the dorsalis pedis artery decre

121 (t-test scores of p < .001) better than PI (pulsatility index) and RI (Doppler calculated in the ute

122 vealed that the new predictors PPI (pressure pulsatility index) and RI (resistance index) calculated

123 s pulmonary capillary wedge pressure, aortic pulsatility index, and cardiac index.

124 flow velocity in the middle cerebral artery, pulsatility index, and jugular bulb oxygenation between

125 or left ventricular end-diastolic dimension, pulsatility index, and power were calculated.

126 ernal mean arterial pressure, uterine artery pulsatility index, brachial artery flow-mediated dilatat

127 s, various temporal waveform metrics such as pulsatility index, percent time in systole and diastole,

128 potential mediators, including renal artery pulsatility index, renal vascular resistance, and arteri

129 feature, including intranodular vascularity, pulsatility index, resistive index, or peak-systolic vel

130 artery resistance index and umbilical artery pulsatility index, respectively.

131 indices of RV dysfunction (pulmonary artery pulsatility index, right atrial pressure:pulmonary capil

132 After accounting for pulsatility index, the relation between aortic stiffness

133 he intensity of trophic skin changes and the pulsatility index.

134 ater risk of mortality (eg, pulmonary artery pulsatility index:hazard ratio, 1.11 per 1-SD increase [

135 entile, or abnormal umbilical/uterine artery pulsatility index; and 2) non-severe IUGR without any of

136 es (mean, total, mean/RR interval; Gosling's pulsatility index; and cerebrovascular resistance [mean

137 Resistive and pulsatility indexes and peak systolic velocity were docu

138 Blood flow rates and pulsatility indexes from 13 major arteries and four veno

139 reased stiffness than using flow or pressure pulsatility indices in isolation.

140 id and aorta, transmission of excessive flow pulsatility into the brain, microvascular structural bra

141 Transmission of excessive flow pulsatility into the low-impedance renal microvasculatur

142 to lower GFR by transferring excessive flow pulsatility into the susceptible renal microvasculature,

143 Furthermore, GnRH pulsatility is altered in common reproductive disorders

144 Assessment of LH pulsatility is important for the clinical diagnosis of r

145 dinated adrenocorticotropic hormone-cortisol pulsatility is maintained.

146 uring acute stress, cortisol levels rise and pulsatility is maintained.

147 Notably, pulsatility is not an outcome of an upstream Rho1 pacema

148 l for proper liver utilization and perturbed pulsatility is observed in type 2 diabetes.

149 This pulsatility is orchestrated by a network of neurons that

150 Evidence exists that appropriate pulsatility is required to maintain endothelial cell hom

151 stasis, but the mechanism behind coordinated pulsatility is still under investigation.

152 Cerebral pulsatility is strongly associated with cerebral small v

153 onary flow elevation from enhanced perfusion pulsatility is synergistically amplified by adenosine.

154 e compared the maximum and mean brain tissue pulsatility (MaxBTP and MeanBTP), as identified by TPI,

155 vascular function and whether modulation of pulsatility may improve vascular remodeling and long-ter

156 creased BTP related to the mean global brain pulsatility (MeanBTP) and no change related to large ves

157 levels of all aortic stiffness and pressure pulsatility measures (beta per SD = 0.40-0.92; P = .001-

158 ficients were greater than 0.90 for flow and pulsatility measures across all vessels.

159 nd interobserver reproducibility of flow and pulsatility measures was assessed in 30 patients.

160 Aortic stiffness and pressure pulsatility measures were not associated with amygdala,

161 n Normal reference values for blood flow and pulsatility obtained using four-dimensional flow MRI sho

162 Ultradian pulsatility of both adrenocorticotropic hormone and cort

163 Coordinated pulsatility of individual islets enhances the first-phas

164 A 27% reduction in the vessel wall pulsatility of intracortical arterioles and widespread l

165 ed good sensitivity to detect changes in the pulsatility of small brain volumes, to identify early an

166 effects of continuous blood flow and reduced pulsatility on major organ function have not been studie

167 rate, pH, hypoxia, venous pressure, and flow pulsatility on NOe were determined.

168 o assess the effects of different degrees of pulsatility on the incidence of nonsurgical bleeding.

169 ure wave pulsatility and greater decrease in pulsatility on treatment are associated with functional

170 evidence of detrimental effects from reduced pulsatility over a 6-month time period.

171 bitrary unit (au) average annual increase in pulsatility over all vessels (age beta = 0.011 au per ye

172 Pulsatility over the cardiac cycle was evaluated by send

173 Further analysis demonstrated that the pulsatility parameters recovered by AutoDecon were indis

174 pulse height; all concentration-independent pulsatility parameters were almost identical in the two

175 ht, as leptin levels rose to their peak, the pulsatility profiles of LH changed significantly and bec

176 bral blood flow and vessel-specific flow and pulsatility, respectively.

177 Aortic pressure pulsatility significantly decreased in subjects with fun

178 Thus, adenosine and perfusion pulsatility specifically interact to enhance coronary fl

179 (+)(Ca) activation and NO comodulate in vivo pulsatility-stimulated coronary flow, supporting an impo

180 Leptin pulsatility therefore can be preserved in the obese.

181 duced changes in thyroid-stimulating hormone pulsatility, thyroid and IGF-1 hormone levels, hypothala

182 ect of aortic arch stiffening on transmitted pulsatility to cerebral vasculature, employing a computa

183 opose that impedance pumping allows arterial pulsatility to drive CSF in the same direction as blood

184 , modulating the amount of pressure and flow pulsatility transmitted into the cerebral microcirculati

185 e increased flow demand and higher perfusion pulsatility typically co-exist.

186 ions between diodicity, early turbulence and pulsatility uncovered here can inform applications in fl

187 e perforating artery blood flow velocity and pulsatility, vascular reactivity to a visual stimulus in

188 ic modulation of the artery, allowing cyclic pulsatility, vasomotion, and adaptative remodelling, by

189 Average blood flow pulsatility was 6% higher in subjects with AMD (0.71 +/-

190 hort, 4D flow MRI data for cerebral arterial pulsatility was collected for 159 participants at baseli

191 Pulsatility was evaluated by means of the LVAD parameter

192 min per male patient +/- 1.77; P = .37), but pulsatility was higher in female patients (sex beta = -0

193 of injection was unaffected, and subsequent pulsatility was inhibited.

194 Pulsatility was introduced using a programmable pneumati

195 Flow augmentation with pulsatility was not linked to higher regional oxygen con

196 spiration-dependent to the cardiac-dependent pulsatility was positively associated with the retrograd

197 Cardiac pulsatility was quantified by using the venous pulsatili

198 The cardiac pulsatility was recorded with a cardiac signal monitor.

199 nstant mean pressure, and physiological flow pulsatility was set at 40 or 100 mm Hg by computer servo

200 e) with valid primary outcome data, cerebral pulsatility was unchanged on sildenafil versus placebo (

201 Pulsatility was unrelated to PS for all regions (p > 0.1

202 Pulsatility was varied between 40 and 100 mmHg.

203 al (Oxford Haemodynamic Adaptation to Reduce Pulsatility) was a double-blind, randomized, placebo-con

204 ffects of 5 microM muscimol to increase GnRH pulsatility were blocked by co-exposure to the GABAA rec

205 e statistics (mean +/- SD) of blood flow and pulsatility were tabulated for the entire group and by a

206 l vessel disease is associated with cerebral pulsatility, white matter hypoperfusion, and reduced cer

207 nsibilitvy, women develop a higher degree of pulsatility with aging, as compared with men.

208 t can potentially benefit from lowering GnRH pulsatility with consequent diminished levels of plasma

209 oduced rapid inhibition of ACTH and cortisol pulsatility within 30 min in the morning and afternoon.

210 null mice restores estrous cyclicity and LH pulsatility without reducing their obese phenotype.