ライフサイエンスコーパス: pup

1 d communication (ultrasonic vocalizations in pups).

2 remained elevated during slower decay at low Pup.

3 cleavage of the isopeptide bond formed with Pup.

4 sing tissue sections from a whole-body mouse pup.

5 of E25s was higher in male than females and pup.

6 st building induces maternal maltreatment of pups.

7 This was already observable in 2-week-old pups.

8 mory and learning ability in OPN(-) OPN(+/+) pups.

9 b specimen cultures or C. muridarum-positive pups.

10 lk-derived OPN on brain development of mouse pups.

11 ctose and for normal growth rates of nursing pups.

12 rol pups but more high frequency calls in MS pups.

13 ed and antibody-probed milk OPN in brains of pups.

14 neovascularization was reduced in Casp-8ECKO pups.

15 as tissues were collected from the remaining pups.

16 n brain and/or lymph nodes of fetuses and/or pups.

17 mber and sex ratios of subsequent litters of pups.

18 dings from calyceal terminals in newborn rat pups.

19 was similar between UPI/OIR and control/OIR pups.

20 tages of development in living, unrestrained pups.

21 n the P0 Mapt(-/-) , but not the Mapt(+/-) , pups.

22 ause any major effect on the survival of the pups.

23 nduced by sodium selenite in male Wistar rat pups.

24 cytic marker GFAP in the cortex of 7-day old pups.

25 GEs were comparable between preterm and term pups.

26 0, but not in D7 preterm relative to D4 term pups.

27 l and the growth of m(+)/p(DeltaS-U) newborn pups.

28 ing lactation as well as the weaning mass of pups.

29 mically and caused a rapid, fatal disease in pups.

30 stinal permeability, were evaluated in these pups.

31 n normal pups receiving NK cells from WT DEP pups.

32 ding females, and the survival and growth of pups.

33 rotection against enterotoxigenic E. coli in pups.

34 n when females were later allowed to produce pups.

35 ere compared between the control and PNE rat pups: 1) the 5-HT content in bronchoalveolar lavage flui

36 7-DHC were observed in the brain of newborn pups 14 days after drug exposure.

37 e average diastolic [Ca] nadir to 200 nM (at Pup = 24 mM/s).

38 fected females delivered significantly fewer pups (3.8 +/- 3.2/mouse) than control females (6.3 +/- 1

39 in juveniles, which had similar body mass to pups (~3-4 months).

40 odendrocytes in the brain of OPN(+) OPN(+/+) pups, accompanied by increased activation of ERK-1/2 and

41 Crucially, pups accumulate certain compounds to levels that are dra

42 ehaviour of control and MS mothers modulated pup acoustic characteristics in opposite directions; hig

43 the uniquely short lactations of true seals, pups acquire a greater proportion of maternal body resou

44 D)6 and continuing with direct dosing of the pups after birth.

45 ethomorph and observed shortened AGD in male pups after gestational exposure.

46 and become pregnant but did not suckle their pups after giving birth (NL), and 3) rats that were allo

47 al antibodies from vaccinated dams protected pups against post-natal ZIKV challenge.

48 Infected IL-27Ralpha(-/-) pups also exhibited improved weight gain and reduced mor

49 maternal retrieval behavior when exposed to pups, an effect linked to disruption of parvalbumin-expr

50 y rearing her pup, by ensuring that both her pup and herself have sufficient energy during this 'ener

51 e 021 (P021), rescued developmental delay in pups and AD-like hippocampus-dependent memory impairment

52 and compared their migratory strategies with pups and adults.

53 intestinal epithelial cells in both suckling pups and adults.

54 Experimental NEC in rat pups and Caco-2 cells had increased permeability compare

55 Tissues from E17.5 embryos, pups and dams were collected for choline/methyl metaboli

56 in size in founder pups and genotype offspring in established transgenic mi

57 of reproductive and metabolic development in pups and has a persistent effect on their subsequent sen

58 then formed in situ preparations from these pups and recorded their 'fictive' patterns from respirat

59 ith certain genetic background yields viable pups, and knockout of the MCU in adult heart does not ca

60 sufficient to cause the apneas in Necdin-KO pups, and that fluoxetine may offer therapeutic benefits

61 Larger wild dog packs produced more pups, and their members experienced higher survival than

62 hoerus grypus) are typical capital breeders; pups are abandoned on the natal site after a brief suckl

63 Moreover, pups are born through natural mating and thrive through

64 New research shows that pups are identified using a combination of generic and '

65 We show that young pups are not constrained to these relations and that new

66 re also more numerous in the LGEs of preterm pups at D3 compared with term rabbits at D0.

67 Across all three sites, packs which reared pups at high ambient temperatures produced fewer recruit

68 Both wildtype and Keap1(f/f) pups at PND1 were exposed to hyperoxia for 72 h and then

69 llowing outcomes between control and PNE rat pups at postnatal days 11-14: 1) the cardiorespiratory r

70 t microbiome composition in both mothers and pups at several different time points.

71 Tissues were collected from pups at week 5 (W5), and their littermates at week 39 (W

72 In this study, we used PND1 pups bearing bearing hypomorphic Keap1 floxed alleles (K

73 not colonization, is strongly age dependent; pups become progressively less susceptible to infection

74 NEC was induced in mouse pups between postnatal day (P) 5 and 9.

75 tero and lactational SSRI exposure on C57BL6 pup bone microarchitecture.

76 Pups born after cPAF and (+)-naltrexone treatment exhibi

77 Consistent with these anatomical deficits, pups born to CB-treated dams exhibited compromised CCK-I

78 following a P. berghei challenge compared to pups born to control dams.

79 Pups born to control mouse dams were suckled from birth

80 strongest effect on the brain of Dhcr7(+/-) pups born to Dhcr7(+/-) dams.

81 In 3 trials, pups born to PbSEA-1-vaccinated dams had significantly l

82 Gestational Delta9-THC exposure resulted in pups born with symmetrical fetal growth restriction, wit

83 FASD pup brains showed evidence of altered acetylcholine avai

84 ted with more low frequency calls in control pups but more high frequency calls in MS pups.

85 ecays to resting Ca levels (<100 nM) at high Pup, but remained elevated during slower decay at low Pu

86 ostnatal day 0 (P0) heterozygous (Mapt(+/-)) pups, but not a complete loss of tau in the Mapt(-/-) li

87 Release propagation is facilitated at higher Pup by a larger LCR amplitude, whereas at low Pup by hig

88 up by a larger LCR amplitude, whereas at low Pup by higher background Ca.

89 mize her chances of successfully rearing her pup, by ensuring that both her pup and herself have suff

90 nd we show that they adapt their response to pup calls during maternal learning in nonmutants, but no

91 o USVs in TeA, improving discriminability of pup calls in mothers compared with naive females.

92 These include compounds that pups cannot synthesise themselves, such as pyridoxine/vi

93 EC-specific Casp-8-KO pups (Casp-8ECKO) showed reduced retina angiogenesis, as

94 were quantitated in sera of individual PND 3 pups collected 1 hr postexposure utilizing ultra-high-pr

95 PCFs) and prolongs PCF-mediated apnea in rat pups, contributing to the pathogenesis of sudden infant

96 We show that during adversity, pup cortical LFP dynamic range decreased during nurturin

97 ed adversity as a benchmark, we assessed rat pup cortical local field potentials (LFPs) and behaviors

98 plays a key role in encoding and perceiving pup cries during motherhood.

99 average rates of maternal daily mass loss or pup daily mass gain between proactive and reactive mothe

100 the sample mean for maternal daily mass and pup daily mass gain than proactive mothers.

101 mass loss rate to indicate expenditure, and pup daily mass gain to indicate within season fitness ou

102 no significant increase in birth defects or pup deaths resulting from prenatal apigenin treatment.

103 defects and deliver only 2% of the number of pups delivered by control females.

104 Full-term pups developed in room air (RA) or an oxygen-induced ret

105 compared to the first isolation, whereas MS pups did the opposite.

106 Consequently, neonatal pups died at birth due to respiratory insufficiency.

107 key node in the neural circuitry underlying pup-directed behaviors and provide important insight int

108 that LB male, but not female preweaning rat pups display increased BLA neuron spine density parallel

109 rgin females do not recognize the meaning of pup distress calls, but retrieve isolated pups to the ne

110 care behavior performed in response to their pups' distress cries.

111 e efficiency of mass transfer from mother to pup during lactation as well as the weaning mass of pups

112 NRF2 loss impaired survival of SCD pups during gestation and in the first 2 months of life.

113 mucus layer but, in contrast to P9 wild-type pups, enabled E. coli K1 bacteria to gain access to epit

114 doses of peanut extract were administered to pups every day for 2 weeks before peanut sensitization a

115 mmunity than direct immunization in 5-wk-old pups (ex vivo assay of pup splenocytes).

116 LCRs at higher Pup exhibit larger amplitudes and faster propagation wit

117 nic cells using the Meox2-Cre driver, female pups exhibit no morbidity or mortality despite partial X

118 t 2, using an experimental BPD-PH model, rat pups exposed to room air or hyperoxia (85% O(2)) were ra

119 Finally, pups exposed to the odor in the presence of the conditio

120 Moreover, pups exposed to WIN in utero lacked constitutive CB1R-me

121 glucose tolerance as early as 5 wk of age in pups fed a Western diet, ultimately causing diabetes.

122 at which group sizes change, referred to as pup flow, is predicted at the critical temperature of th

123 ence failed to block threat learning at PN14 pups following abuse, and mesolimbic dopamine engagement

124 dopaminergic (DA) neurons of the VTA in rat pups following perinatal alcohol and joint nicotine-alco

125 o mate and become pregnant and suckled their pups for 21 days before weaning (L).

126 cessed brain sections from seal and sea lion pups for Nissl substance, cytochrome oxidase, and vesicu

127 tometry on spleens and thymi from 3-week-old pups for T- and B-cell subsets and epithelial cells did

128 resulted in serotype-specific protection of pups from a lethal challenge with GBS.

129 esterol ratio is the highest in Dhcr7(+/)(-) pups from Dhcr7(+/)(-) mothers exposed to ARI, underscor

130 were bred in-house and both male and female pups from multiple litters were injected with lipopolysa

131 cts of daily maternal separation (MS) of rat pups from postnatal days 2-10 (PND2-10) on neurobehaviou

132 Pups from two parity cycles were included in this study.

133 and dive data from recently-weaned grey seal pups from two regions of the United Kingdom (the North S

134 Heterozygous TLR2(+/-) pups from wild-type (WT) or TLR2(-/-) dams were fed eith

135 Here we show that pup gathering behaviour and associated auditory cortical

136 Pup growth and survival are also reduced during periods

137 N-S-LYS and N-S-DHA pups had a less permeable mucus barrier relative to N-S

138 at developed normally for over a year, 9V;C* pups had a lethal skin defect as did 0S;C* mice resemble

139 ry pattern of the sham rat pups, injured rat pups had increased fR and predictability.

140 Furthermore, sodium selenite- injected rat pups had significantly higher levels of malondialdehyde,

141 dial PFC (mPFC) of maternally separated (MS) pups identified an increased expression of myelin-relate

142 oduced fewer recruits than did those rearing pups in cooler weather; at the non-seasonal Kenya site s

143 egative for wild-type virus, unlike those of pups in the control group, with GPCMV transmission being

144 The target organs of pups in the vaccine group were negative for wild-type vi

145 Postnatal growth restriction occurred in pups in UPI/RA, but not in UPI/OIR.

146 l age but the efficiency of mass transfer to pups increases, suggestive of selective disappearance of

147 Feeding high doses of peanut to pups induced tolerance to peanut protein.

148 with the ventilatory pattern of the sham rat pups, injured rat pups had increased fR and predictabili

149 allows for active pup protection and mother-pup interactions crucial for pup threat learning.

150 the transient formation of a phosphorylated Pup-intermediate.

151 (DMT1) and ferroportin were not affected by pup iron status at 10 d of age but were strongly affecte

152 This mummified wolf pup is important to the local Tr'ondek Hwech'in people,

153 e the same vocalization deficit in 8-day-old pup isolation calls and do not affect other nonvocal beh

154 However, unlike widely-dispersed pups, juvenile male and female NFS dispersed in differen

155 nd molecular analyses indicate that hSRY(ON) pups lack innate suckling activities, and develop fatty

156 Unlike neonatal pups, late gestation fetuses proved to be resistant to r

157 While at low Pup LCRs show smaller amplitudes, their larger durations

158 Furthermore, the Pup ligase PafA and the depupylase Dop share close struc

159 During this isolation, control pups made longer and louder low frequency calls compared

160 Moreover, pups may undergo a period of development after weaning d

161 A phosphorylation were demonstrated in a rat pup model of NEC.

162 tested this hypothesis using an in vivo rat pup model, an in vitro model of experimental NEC, and hu

163 AMA mice (38-41 weeks) at E17.5 had fewer pups, more late fetal deaths, reduced fetal weight, incr

164 The wolf pup mummy was recovered along a small tributary of Last

165 Subsequently, pups (n = 4 . time(-1)) were killed at 13 different time

166 In mice, pup-naive virgin females do not recognize the meaning of

167 ght and viability at term and a reduction in pup number at weaning, but does not influence postnatal

168 nuria, lower maternal and pup weights, lower pup number, renal injury, and a larger heart compared to

169 in birth weights of UPI/OIR vs. control/OIR pups occurred.

170 of KCC2, thereby delaying the GABA switch in pups of both sexes.

171 erebellar external granule layer of P2 mouse pups of both sexes.

172 environment, we reciprocally cross-fostered pups of both species.

173 Pups of FASD mothers displayed short-term memory impairm

174 aracteristic of the microbiome of unfostered pups of the same genotype within 2 months.

175 programming of WAT progenitors isolated from pups on the postnatal day (PND) 1 and 21.

176 d of week 2 (postpartum day 14) when the rat pups opened their eyes.

177 ut (KO) dams producing OPN(-) milk nursed WT pups (OPN(+/+)), yielding 2 pup treatment groups, OPN(+)

178 and significantly fewer Klotho heterozygous pups originated from gcKL knockdown mice than would be e

179 stered prenatally to the dams and fed to the pups over their lifetimes.

180 ned the serum metabolomes of five mother and pup pairs of Atlantic grey seals, Halichoerus grypus, fr

181 ation used congenic/syngeneic dam and foster pup pairs.

182 stockpiling of critical metabolites in their pups, potentially depleting their own reserves and promp

183 nalysis of hippocampi isolated from neonatal pups prenatally exposed to BPA was conducted and reveale

184 Skipping breeding increased subsequent pupping probability substantially for low mass females.

185 However, in the second isolation, MS pups produced a greater proportion of high (~60 kHz) vs

186 robenzene sulfonate (TNBS) in 10-d-old mouse pups produces an acute necrotizing ileocolitis resemblin

187 wever, 35% of the variability in NZ sea lion pup production is explained by latent by-catch, and the

188 Scottish breeding colonies with contrasting pup production trends.

189 marginally greater at IM (increasing/stable pup production) than at NR (decreasing).

190 t self-defense suppression allows for active pup protection and mother-pup interactions crucial for p

191 , especially during the energetically costly pup-rearing period.

192 es to brief isolation at PND12 compared with pups receiving controlled handling without MS.

193 Relative to wild-type pups receiving high perinatal n-6/n-3 ratios, subcutaneo

194 neous adipose tissue in 14-day-old wild-type pups receiving low n-6/n-3 ratios had more adipocytes th

195 at lacked NK cells and was induced in normal pups receiving NK cells from WT DEP pups.

196 Pups receiving the C57BL/6J or BALB/cJ mitochondrial gen

197 es, revealing an unexpected logic underlying pup recognition and ensuing infanticide.

198 from postnatal day 1: MS180) whilst control pups remained unhandled.

199 C57BL/6 mouse pups rendered anemic by timed phlebotomy and then given

200 Transmission from nasally colonized pups required high levels of bacterial shedding in nasal

201 rog/ml CSC neonatally had increased rates of pup resorption.

202 onal transfer to nonimmunized BALB/cJ foster pups resulted in much greater immunity than direct immun

203 rhesus rotavirus (RRV) infection of newborn pups results in a cholangiopathy paralleling human BA an

204 atterns of the in situ preparations from ALI pups retained these characteristics despite removing the

205 (ISIs) from 75 to 375 milliseconds elicited pup retrieval, and cortical responses were generalized a

206 irs auditory-driven maternal preference in a pup-retrieval assay.

207 nusual paternal care in rats, as measured by pup-retrieval tests.

208 apnea by prenatal nicotinic exposure in rat pups: role of 5-HT(3) receptors.

209 dam immunogen are the product of the foster pup's thymus.

210 elative reserves allocated by a mother and a pup's weaning mass but that the efficiency of mass trans

211 urturing handling by examining its impact on pup separation-reunion with the mother.

212 During reunion, adversity-experiencing pups showed aberrant interactions with mother and blunte

213 ocytes derived from XLalphas knockout (XLKO) pups showed enhanced transferrin internalization.

214 All Has2(f/f);Hand2-Cre pups showed reduced mandible size and about 50% of them

215 ock conditioning in postnatal day (PN)14 rat pups showed that maternal presence blocked fear learning

216 All mothers abandoned their pups, showing that prolactin action on MPOA neurons is n

217 rgin male mice naturally kill another male's pups so they can sire their own offspring.

218 ied carcass of an ancient wolf (Canis lupus) pup (specimen YG 648.1) was discovered in thawing permaf

219 ge, 82% of immunogen-responding cells in the pup spleen were produced through maternal educational im

220 Depletion of maternal Foxp3(+) cells from pup splenocytes illustrated a substantial role for lacta

221 unization in 5-wk-old pups (ex vivo assay of pup splenocytes).

222 Blocking pup stress hormone during either adversity or reunion re

223 Unfortunately, nearly all RRV-infected pups succumb by day of life 14.

224 permeable mucus layer relative to 21 day old pups, suggesting immaturity may contribute to exposure o

225 duction strategy without adversely affecting pup survival and well-being, and housing of adult mice a

226 + LF(-) significantly increased livebirths, pup survival, and litter size compared to LPS alone.

227 arization was remarkably lower in Keap1(f/f) pups than in wildtype counterparts (28.9% vs 2.4%, wildt

228 or preventing NEC in a mouse model, in which pups that are reared by IgA-deficient mothers are suscep

229 predisposition to AAD did not develop in DEP pups that lacked NK cells and was induced in normal pups

230 of status epilepticus in postnatal day 7 rat pups that results in widespread neuronal injury, we foun

231 Heterozygous TLR2(+/-) pups that were born to and nursed by TLR2(-/-) dams exhi

232 By challenging pups that were fostered by either maternal antibody-suff

233 amined LCR regulation by SR Ca pumping rate (Pup) that provides a major contribution to fight-or-flig

234 e end of breeding were less likely to bear a pup the following year.

235 In Necdin-KO pups, the genetic deletion of Slc6a4 or treatment with F

236 tion and mother-pup interactions crucial for pup threat learning.

237 periments were performed on whole-body mouse pup tissue demonstrating the separation of closely isoba

238 chment of prokaryotic ubiquitin-like protein Pup to lysine side chains of the target protein via an i

239 To address this, we exposed mouse pups to a prototypical general anesthetic, isoflurane (I

240 ndromic repeats (CRISPR)-Cas9, sensitized P9 pups to E. coli K1 bacteremia.

241 d in a more naturalistic context by exposing pups to interactions with the mother treating them rough

242 of pup distress calls, but retrieve isolated pups to the nest after having been co-housed with a moth

243 ress avoidance, and support approach towards pups, to promote maternal care?

244 ) milk nursed WT pups (OPN(+/+)), yielding 2 pup treatment groups, OPN(+) OPN(+/+) and OPN(-) OPN(+/+

245 Sprague Dawley rat pups underwent 14 days of postnatal maternal separation

246 Pups used the neonatal Fc receptor to transfer IgG from

247 recorded the ventilatory pattern of the rat pups using flow-through plethysmography, then formed in

248 ing, increased social dominance, and reduced pup USV.

249 g mice drives primary myelination in newborn pups via secretion in breast milk, whereas genetically b

250 ut also inhibited delivery while maintaining pup viability in a noninflammatory model of preterm part

251 2020) target neurons activated by ultrasonic pup vocalizations and discover a functional synaptic net

252 neurons further exhibit sharpened tuning for pup vocalizations following maternal experience.

253 that is selective for behaviorally relevant pup vocalizations.

254 Lack of hypoalveolarization in Keap1(f/f) pups was accompanied by increased levels of expression o

255 Direct contact between pups was not required for transmission indicating the im

256 In rat pups, we intratracheally injected either bleomycin to in

257 ivo calcium imaging in un-anesthetized mouse pups, we show that spatially segregated functional assem

258 f-function and reconstitution experiments in pups, we showed that NK cells and granzyme B were requir

259 sociated with proportion mass allocation and pup weaning mass, but mass transfer efficiency was predi

260 to weight, we included a genetic analysis of pup weight at birth and weaning.

261 Pup weights and serum and mRNA of liver and kidney VEGF,

262 Milk yield and pup weights were recorded throughout lactation.

263 Litters from ERKdko females and pup weights were reduced coincident with delayed parturi

264 Alveolar morphology, milk yield, and pup weights were similar.

265 od pressure, proteinuria, lower maternal and pup weights, lower pup number, renal injury, and a large

266 everity and intestinal microbiome changes in pups were also associated with significantly decreased c

267 vaccinated 3 weeks apart with DeltagD-2, and pups were challenged at different times postnatally with

268 Protection was reduced when pups were challenged on Day 1 of life, and this was asso

269 aamniotic injection at Embryonic Day 20, and pups were delivered by cesarean section at Embryonic Day

270 Pups were delivered by cesarean section at Embryonic Day

271 C57BL/6J mouse pups were exposed to 85% oxygen or room air from P2-P14.

272 Rat pups were exposed to an Adversity-Scarcity model from po

273 males and two females, whereas the remaining pups were fed either a high- or low-fat diet until PND10

274 In addition, Dhcr7(+/)(-) pups were more vulnerable to maternal ARI exposure than

275 Thus, NEC-stressed (N-S) rat pups were orally dosed with breastmilk components lysozy

276 an odor, froze when tested alone, whereas if pups were present, they remained in close contact with t

277 Likewise, Keap1(f/f) pups were protected against prolonged (96 h) hyperoxia-i

278 s of maltreatment-induced vulnerability, rat pups were reared from postnatal day 8 (PN8) with a maltr

279 After breeding male turnover, fewer female pups were recruited in the new males' litters.

280 Furthermore, neonatal pups were rendered resistant to RRV-mediated liver injur

281 On postnatal day 15 pups were sacrificed and skulls underwent micro-computed

282 Mutant pups were severely stunted during the suckling period, b

283 P23H rat pups were treated with 830 nm light (180 s; 25 mW/cm(2);

284 Therefore, aralar-KO pups were treated without distinction of gender with dai

285 Mass measurements of 531 mothers and pups were used with Bayesian hierarchical models to expl

286 predicted to produce a shortened AGD in male pups, whereas two (lambda-cyhalothrin, pyrimethanil) wer

287 munized dams transfer maternal antibodies to pups, which protect neonates against ZIKV infection.

288 less permeable mucus barrier relative to N-S pups, which suggests the potential of these factors to s

289 experiments of wild-type pups with Nod2(-/-) pups, which then acquired altered cutaneous bacteria and

290 proportions of their body reserves to their pups, which they then abruptly wean.

291 iation of oligodendrocytes similar to the MS pups, while chemogenetic activation normalised it in the

292 inal (GI) colonization of 2-day-old (P2) rat pups with Escherichia coli K1 results in translocation o

293 Pups with hSRY activated (hSRY(ON)) are born of similar

294 ge compartment in wild-type mice, but not in pups with IKKbeta deletion in Lysm(+) cells.

295 Furthermore, pups with Lysm-IKKbeta deletion had improved survival an

296 Chronic treatment of homozygous mouse pups with NMDA receptor antagonists significantly delaye

297 in cross-fostering experiments of wild-type pups with Nod2(-/-) pups, which then acquired altered cu

298 th PbSEA-1, mated them, and challenged their pups with P. berghei ANKA parasites to assess the impact

299 anges with time were particularly evident in pups, with indications of strain in the fat and energy m

300 ZIKV was stochastic, in that not all fetuses/pups within the same dam had detectable virus and infect