ライフサイエンスコーパス: purified protein derivative

1 or Quil-A did not sensitize mice to M. bovis purified protein derivative.

2 e stimulated with DEP and M. tuberculosis or purified protein derivative.

3 zyme-linked immunospot responses against BCG purified protein derivative.

4 in greater numbers than T cells reactive to purified protein derivative.

5 red to responses induced by M. bovis-derived purified protein derivative.

6 following restimulation with M. tuberculosis purified protein derivative.

7 call antigen response by PBMCs to tuberculin purified protein derivative.

8 However, 48 h after tuberculin purified protein derivative administration in the ipsila

9 to MOG-35-55 peptide, and to a lesser degree purified protein derivative and Con A, but had no inhibi

10 L-2 production after both Mycobacteria bovis purified protein derivative and Schistosoma mansoni egg

11 +-T-cell activation than the soluble antigen purified protein derivative and that these cells are act

12 gamma release was significantly reduced when purified protein derivative- and Ag85B-specific CD4(+) T

13 d toward the rESAT-6-CFP10 fusion protein or purified protein derivative are comparable and that reca

14 uate its potential to replace tuberculin, or purified protein derivative, as the rapid diagnostic of

15 predictors of survival were found: anergy to purified protein derivative, atypical chest roentgenogra

16 This relationship was restricted to purified protein derivative because maternal infection s

17 NP-modified autologous melanoma cells and to purified protein derivative developed in almost all pati

18 Purified protein derivative-driven T cell IFN-gamma prod

19 Purified protein derivative ELISPOT responses increased

20 in skin test, and (4) Battey skin test using purified protein derivative from the Battey bacillus.

21 memory cells specific for tetanus toxoid and purified protein derivative in 18 healthy individuals an

22 onse to bead-immobilized Mycobacterium bovis-purified protein derivative in aged mice.

23 When exposed to purified protein derivative in vitro, young and old CD11

24 gens can overcome specificity limitations of purified protein derivatives in the detection of bovine

25 Interestingly, whereas purified protein derivative induced such cells in both L

26 the expression of I kappa B-alpha mRNA, and purified protein derivative induced the activation of NF

27 Further, M. tuberculosis and its tuberculin, purified protein derivative, induced the degradation of

28 Conversely, purified protein derivative-induced (but not concanavali

29 The production of M. tuberculosis and purified protein derivative-induced IFN-gamma, TNF-alpha

30 gamma response to Mycobacterium tuberculosis purified protein derivative (Mtb PPD) in UK adolescents,

31 Compared with those in tuberculin (purified protein derivative)-negative control subjects,

32 T cells were expanded from purified protein derivative-negative controls, persons w

33 ,300 compared with 1/16,000 +/- 7,000 in six purified protein derivative-negative controls.

34 nonuclear cells from 15/26 sarcoidosis, 1/24 purified-protein-derivative-negative (PPD-) (P < 0.0001,

35 ng 10 tuberculosis (TB)-infected subjects, 8 purified-protein-derivative-negative subjects, and 7 pur

36 The induction of TNF-alpha and IL-1 by purified protein derivative of M. tuberculosis was signi

37 Upon stimulation with purified protein derivative of M. tuberculosis, CD4+ T c

38 antigen and the level is as high as that to purified protein derivative of M. tuberculosis.

39 nylate cyclase of Bordetella pertussis), and purified protein derivative of M. tuberculosis.

40 ssociated with a reduced Mantoux response to purified protein derivative of M. tuberculosis: 60% of t

41 CBA mice by embolization of beads coupled to purified protein derivative of Mycobacteria tuberculosis

42 by embolizing Sepharose beads coupled to the purified protein derivative of Mycobacterium bovis or so

43 production of IFN-gamma after challenge with purified protein derivative of Mycobacterium bovis.

44 cells), much weaker than the response to the purified protein derivative of Mycobacterium tuberculosi

45 increased the in vitro cytokine responses to purified protein derivative of Mycobacterium tuberculosi

46 ayed-type hypersensitivity (DTH) response to purified protein derivative of tuberculin (PPD), the exp

47 cells specific for 2 other common antigens: purified protein derivative of tuberculin and Candida al

48 Polyclonal and purified protein derivative of tuburculin-specific T-cel

49 igated by T cell proliferation to tuberculin purified protein derivative or allogeneic responses to F

50 as induced by bead-immobilized mycobacterial purified protein derivative or Schistosoma mansoni egg a

51 nge of primed mice with either mycobacterial purified protein derivative or schistosomal egg Ag-coate

52 , unlike the mouse system, supernatants from purified protein derivative- or concanavalin A-stimulate

53 ensitized CBA/J mice with Mycobacteria bovis purified protein derivative- or Schistosoma mansoni egg

54 .v. challenge with either Mycobacteria bovis purified protein derivative- or Schistosoma mansoni egg

55 n in response to BCG lux (P < 0.0001) and to purified protein derivative (P = 0.0001).

56 ure filtrate protein-10 (CFP10) are found in purified protein derivative positive donors, suggesting

57 absence of anti-LipC antibodies in sera from purified protein derivative-positive (PPD+) healthy subj

58 heral blood mononuclear cells of a number of purified protein derivative-positive (PPD+) human donors

59 cited pluripotent CD4 and CD8 T responses in purified protein derivative-positive donor PBMCs.

60 this is the immunodominant response for this purified protein derivative-positive donor.

61 in the context of host responses in healthy purified protein derivative-positive donors and infected

62 les for their ability to stimulate PBMC from purified protein derivative-positive healthy individuals

63 cited strong Th1 T cell responses in healthy purified protein derivative-positive human PBMC and in m

64 peripheral blood mononuclear cells in 70% of purified protein derivative-positive individuals without

65 In one purified protein derivative-positive subject, 192 clones

66 e effector cell frequency among five healthy purified protein derivative-positive subjects was 1/7,60

67 ) TB(+) patients tested but not in sera from purified-protein derivative-positive healthy controls, s

68 Nonadherent cells of purified-protein-derivative-positive donors mediated equ

69 a pigs were frequently identified in healthy purified-protein-derivative-positive or BCG-vaccinated i

70 -protein-derivative-negative subjects, and 7 purified-protein-derivative-positive subjects.

71 y peripheral blood leukocytes after M. avium purified protein derivative PPD antigen stimulation show

72 with the stability of skin test responses to purified protein derivative (PPD) and candida antigens i

73 /chemokine microenvironment before and after purified protein derivative (PPD) and mannosilated lipoa

74 Whole-blood samples were stimulated with purified protein derivative (PPD) and phytohemagglutinin

75 pathogen antigens (Ags), Mycobacteria bovis purified protein derivative (PPD) and Schistosoma manson

76 dritic cells infected with TB or pulsed with purified protein derivative (PPD) but did not respond to

77 aradoxical responses and received tuberculin purified protein derivative (PPD) in Group 1 had their t

78 lar lavage (BAL) fluid after incubation with purified protein derivative (PPD) in human immunodeficie

79 T cell blastogenesis in response to purified protein derivative (PPD) in PBMCs of TB patient

80 Brugia malayi antigen (BMA) or mycobacterial purified protein derivative (PPD) in the presence of neu

81 e examined in response to concanavalin A and purified protein derivative (PPD) in vitro.

82 roliferate in response to concanavalin A and purified protein derivative (PPD) in vitro.

83 To investigate this, we injected tuberculin purified protein derivative (PPD) into the skin of immun

84 Purified protein derivative (PPD) is a widely used reage

85 ) HIV-seronegative patients had reactions to purified protein derivative (PPD) of > or = 2 mm (OR = 0

86 ranulomas were elicited by beads coated with purified protein derivative (PPD) of Mycobacteria bovis

87 ced by embolizing Sepharose beads coupled to purified protein derivative (PPD) of Mycobacterium bovis

88 d mice by embolization with beads coupled to purified protein derivative (PPD) of Mycobacterium bovis

89 We have used human CD4+ T cells specific for purified protein derivative (PPD) of Mycobacterium tuber

90 r delayed-type hypersensitivity responses to purified protein derivative (PPD) of tuberculin.

91 -vaccinated guinea pigs were stimulated with purified protein derivative (PPD) or M. tuberculosis H37

92 nfected cattle were stimulated with M. bovis purified protein derivative (PPD) or pokeweed mitogen (P

93 m HIV-infected individuals with a history of purified protein derivative (PPD) positivity but not in

94 s were cocultured with autologous T-Regs and purified protein derivative (PPD) preprimed T-Reg-deplet

95 tive therapy trial in Uganda with an initial purified protein derivative (PPD) response < 5 mm comple

96 tality while inducing more BCG reactions and purified protein derivative (PPD) responses (secondary o

97 tality while inducing more BCG reactions and Purified Protein Derivative (PPD) responses (secondary o

98 accination may induce persistent and booster purified protein derivative (PPD) responses that complic

99 11 (17%) of 66 with a history of a positive purified protein derivative (PPD) skin test acquired M.

100 The purified protein derivative (PPD) skin test has been use

101 Purified protein derivative (PPD) skin testing is used t

102 ination, laboratory evaluation, and standard purified protein derivative (PPD) testing (Mantoux metho

103 Delayed hypersensitivity response to purified protein derivative (PPD) tuberculin and mumps a

104 cobacterium avium sensitin (MAS) RS 10/2 and purified protein derivative (PPD) was conducted on patie

105 human experimental system whereby tuberculin purified protein derivative (PPD) was injected into the

106 respectively, in response to MTB (H37Ra) or purified protein derivative (PPD) was investigated.

107 l myristate acetate (PMA) plus ionomycin, or purified protein derivative (PPD) was studied in vitro.

108 une response, elicited by Mycobacteria bovis purified protein derivative (PPD) was unaffected by CCR8

109 Recently, M. tuberculosis and purified protein derivative (PPD) were demonstrated to i

110 lin skin tests (induration, > or =5 mm) with purified protein derivative (PPD) were randomly assigned

111 because of the antigenic cross-reactivity of purified protein derivative (PPD) with M bovis BCG vacci

112 and interferon gamma production from healthy purified protein derivative (PPD)(+) donors.

113 coidosis patients compared with 0 of 11 (0%) purified protein derivative (PPD)(-) (P = 0.0059) and 4

114 In the present study, Th1 (purified protein derivative (PPD)) and Th2 (schistosome

115 (DM), diphencyprone (DPCP), nickel (Ni), and purified protein derivative (PPD)) to the backs of 40 he

116 have long been detected by skin testing with purified protein derivative (PPD), a complex mix of part

117 TH to vaccine (P =.0001) but not with DTH to purified protein derivative (PPD), a control antigen.

118 Phytohemagglutinin (PHA), purified protein derivative (PPD), and T cell epitope pe

119 ed in response to the mycobacterial antigens purified protein derivative (PPD), antigen 85, and manno

120 igens, including lipoarabinomannan (LAM) and purified protein derivative (PPD), in HIV-negative adult

121 osis of both active and latent tuberculosis, purified protein derivative (PPD), lacks specificity and

122 pment of pulmonary granulomas in response to purified protein derivative (PPD), mice presensitized to

123 une competence was assessed by skin tests to purified protein derivative (PPD), mumps, and candida.

124 Purified protein derivative (PPD), nickel, diphencyprone

125 overnight in separate wells with tuberculin purified protein derivative (PPD), saline, and mitogen c

126 y (DTH) reaction to intradermal injection of purified protein derivative (PPD), we investigated the e

127 ic IgG, bulk Fc domain, bulk Fab domain, and purified protein derivative (PPD)- and Ag85A-specific Ig

128 significantly augment the mycobacterial Ag, purified protein derivative (PPD)-driven lymphocyte prol

129 nocyte-derived macrophages co-incubated with purified protein derivative (PPD)-driven peripheral bloo

130 In addition, neither sera from purified protein derivative (PPD)-negative (0 of 29) nor

131 d HIV-positive, TB-positive patients but not purified protein derivative (PPD)-negative or PPD-positi

132 In contrast, nonadherent cells (NAC) from purified protein derivative (PPD)-positive and PPD-negat

133 th MDRTB were compared with those of healthy purified protein derivative (PPD)-positive and PPD-negat

134 Natural killer (NK) cells isolated from both purified protein derivative (PPD)-positive and PPD-negat

135 In purified protein derivative (PPD)-positive donors, PPD-s

136 ted for their ability to stimulate PBMC from purified protein derivative (PPD)-positive healthy donor

137 y approximately 50% when compared to healthy purified protein derivative (PPD)-positive household con

138 blood mononuclear cells (PBMC) from healthy purified protein derivative (PPD)-positive individuals o

139 Purified protein derivative (PPD)-specific immune recove

140 isease coincided with the restoration of BCG purified protein derivative (PPD)-specific T-cell immune

141 At the time of diagnosis, purified protein derivative (PPD)-stimulated production

142 o Toll-like receptor (TLR)-2, -4 or -7/8, or purified protein derivative (PPD).

143 heir lack of dermal reactivity to tuberculin purified protein derivative (PPD).

144 ulosis (TB) diagnosis using bovine and avian purified protein derivatives (PPD-B and PPD-A).

145 uring both the 2-wk immunization period with purified protein-derivative (PPD) and the subsequent lun

146 77 years, HIV-1 seropositive, had a positive purified-protein derivative (PPD) skin test reaction of

147 ntigen and 2 tuberculosis-specific antigens (purified protein derivative [PPD] and ESAT-6/CFP10), fol

148 isease, and (iii) M. tuberculosis infection (purified protein derivative [PPD] positive) and no infec

149 Tuberculin (purified protein derivative [PPD])-induced lymphoprolife

150 soluble protein antigens of M. tuberculosis (purified protein derivative [PPD]).

151 Tuberculin Purified Protein Derivatives (PPDs) exhibit multiple lim

152 ely dependent on the skin test that utilizes purified protein derivatives (PPDs) of tuberculin.

153 Tetanus toxoid reactive clones and a purified protein derivative reactive line failed to resp

154 In a study of 114 healthy purified protein derivative-reactive subjects and 89 pat

155 en both vaccines were administered together, purified protein derivative responses were enhanced in f

156 cells from healthy donors who had a positive purified protein derivative skin test but not from tuber

157 Immunization with BCG generated low purified protein derivative-specific CD4 T cell response

158 We observed that purified protein derivative-specific human CD4(+) T lymp

159 cells coincided with increases in numbers of purified protein derivative-specific interferon- gamma -

160 Cellular responses to purified protein derivative stimulation did not differ b

161 g a basal activation state in the absence of purified protein derivative stimulation, defined in part

162 criptional responses were observed following purified protein derivative stimulation.

163 Adjusted rates of purified protein derivative testing and Papanicolaou sme

164 f IFN-gamma ELISPOT responses to recall Ags (purified protein derivative, Tetanus toxoid, or flu/EBV/

165 ovirus during the sensitization phase of the purified protein derivative Th1-type model significantly

166 and IL-12 were significantly reduced in the purified protein derivative Th1-type response, whereas I

167 more IFN-gamma in response to mycobacterial purified protein derivative than children of helminth-in

168 r recall Ags (influenza, n = 43, p < 0.0001; purified protein derivative tuberculin, n = 6, p = 0.029

169 d immune responses to mycobacterial antigen (purified protein derivative) were assayed using splenocy

170 enic target 6 (ESAT6) protein or tuberculin (purified protein derivative) with interferon-gamma ELISP