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1 nd 21 years, during which lung volume nearly quadruples.
2 seroconversion (a Vi IgG level that at least quadrupled 28 days after vaccination) was 99% in the TCV
5 1 undergoes constitutive degradation in pp2c quadruple abi1/abi2/hab1/pp2ca mutant plants, revealing
6 generated a recombinant PEDV, KDKE(4A), with quadruple alanine substitutions in the catalytic tetrad
8 ndem mass spectrometry analysis using triple quadruple analyser and operated in the multiple reaction
10 performance liquid chromatography coupled to quadruple and time-of-flight mass spectrometers (UPLC-QT
11 tra high pressure chromatography (UPLC) with quadruple and time-of-flight mass spectrometry (Q/TOF, T
14 Concurrent mutation of the four genes in a quadruple Arabidopsis mutant resulted in increased defen
19 ly opposite barrels of a laser-pulled quartz quadruple-barreled pipet and filling the open channels w
22 ANP, E5R, and Nac1 (BEN) domain 3 (BEND3), a quadruple BEN domain-containing protein, localizes in nu
23 pyrenes were synthesized through a double or quadruple benzannulation reaction of alkynes promoted by
24 ates of opioid overdose in the United States quadrupled between 1999 and 2017, reaching a staggering
25 ur delocalized Au-H-Au bonds, similar to the quadruple bond first discovered in the [Re(2) Cl(8) ](2-
27 1 and 3 that lack the quadruply bonded M(A)[quadruple bond]M(A) groups, though the magnitude of the
28 tal atom positions such that the linear M(A)[quadruple bond]M(A)...M(B) array for a given molecule in
30 xcited states of the compounds containing MM quadruple bonds trans-M(2)(T(i)PB)(2)(O(2)CC(6)H(4)-4-CN
31 ue of the satellite industry would more than quadruple by 2040-increasing from around $600 billion un
32 s study that modification of Gs within the G quadruple by 7-deaza-guanine or 7-deaza-2'-O-methyl-guan
33 imated to be 1245 million and is expected to quadruple by the end of the century, necessitating the b
34 in response to increases in [Ca(2+)](i), the quadruple Ca(2+)-ligand mutant does not bind Ca(2+) but
35 ty of Ca(V)2.3 was nearly abolished with the quadruple Ca(V)beta3 Leu mutant L200G/L303G/L337G/L342G.
36 A-containing phases in double-, triple-, and quadruple-cation lead halides in bulk and in a thin film
37 quadrastable, which enables direct study of quadruple cell fate determination on an engineered lands
41 ted physical mixtures of double, triple, and quadruple combinations of neutralizing MAbs targeting fo
42 mine whether a 5-day levofloxacin-containing quadruple concomitant regimen was as safe and effective
55 he annual number of KAH recipients more than quadrupled during the study period from 24 in 1995 to 99
61 GPa and 165 degrees C (where it exists in a quadruple equilibrium, together with an aqueous fluid an
62 (HMONs) with mono, double, triple, and even quadruple framework hybridization of diverse organic moi
63 s the "4X cell", for signal detection at the quadruple frequency multiple was implemented and charact
65 e-adjusted prevalence of atrial fibrillation quadrupled from 20.4 to 96.2 cases per 1000 person-years
66 endonucleases across the 20 NCLDV was nearly quadrupled from 36 to 132, covering much of the structur
67 ated to the symmetry of the particle, and a "quadruple-gear-like" interlocking pattern is observed.
71 with a risk of graft loss that was more than quadrupled (hazard ratio, 4.78; 95% confidence interval
72 Q, IRT1H156Q, IRT1H158Q, IRT1H160Q, IRT14HQ (quadruple His mutant), IRT1K146R, IRT1K171R, and a doubl
75 on regarding their association via triple or quadruple hydrogen bonding, which is controlled by the c
76 e, we computationally studied two tautomeric quadruple hydrogen-bonded systems, DDAA-AADD and DADA-AD
77 , we describe a readily accessible AAAA-DDDD quadruple hydrogen-bonding array that exhibits exception
80 agents based on high-affinity, high-fidelity quadruple hydrogen-bonding units (e.g., DAN.DeUG, Kassoc
81 hondrial protein levels, we have developed a quadruple immunofluorescence method to accurately quanti
83 bnormalities in disease, we have developed a quadruple immunofluorescent technique enabling the quant
84 ed in primary rat hippocampal neurons, using quadruple immunolocalization against endogenous proteins
87 atric donors after cardiac death (PDCD) have quadrupled in the past 9 years, but little data exist on
92 to 2g, effectively doubling body weight and quadrupling induced power requirements; (2) increase fla
97 ll (RF) and throughfall (TF) together with a quadruple isotope approach, which combines delta(18) O,
105 2 construct into hsfa1a/hsfa1b/hsfa1d/hsfa1e quadruple knockout (QK) and wild-type (Wt) backgrounds t
107 enerated two independent pal1 pal2 pal3 pal4 quadruple knockout mutants, which are stunted and steril
111 DTs and used to generate double, triple, and quadruple knockouts (KOs) in different combinations.
112 ants was reduced approximately 10-fold, with quadruple knockouts showing morphological abnormalities.
114 atography (LC) electrospray ionization (ESI)-quadruple linear ion trap (Q-LIT) mass spectrometry (MS)
115 erated an Arabidopsis (Arabidopsis thaliana) quadruple loss-of-function mutant affecting p24 genes fr
116 this study, we generated double, triple, and quadruple loss-of-function mutants of all four members o
117 ralizing activities of double-, triple-, and quadruple-MAb combinations targeting four distinct epito
118 tion by gas chromatography coupled to single quadruple mass spectrometers (GC-SQ/MS) was used for the
119 hy coupled to electrospray ionization triple quadruple mass spectrometry (LC-ESI-MS/MS) was developed
120 r to liquid chromatography coupled to triple quadruple mass spectrometry (LC-MS/MS) analysis of targe
122 As determined by gas chromatography-triple quadruple mass spectrometry, the mean PCB level in mater
123 s localized to the apicoplast, a specialized quadruple membrane organelle, suggesting that separate a
124 s in FcgammaRI/II/III/IV-deficient (FcgammaR quadruple(-/-)) mice, and the cross-presentation ability
130 the Tiam2 PSD-95/Dlg/ZO-1 (PDZ) domain and a quadruple mutant (QM), engineered by swapping the identi
131 l 12 mismatches using an engineered RB69 pol quadruple mutant (qm, L415A/L561A/S565G/Y567A) that enab
133 a previous study, direct administration of a quadruple mutant albumin-fused butyrylcholinesterase tha
135 k and round prey peptidoglycan, results in a quadruple mutant Bdellovibrio which leaves prey-shaped g
137 function-based purification of wild-type and quadruple mutant capsid proteins, which relies on the in
140 ation in vitro; however, specific triple and quadruple mutant combinations were constructed that prom
142 ry high drug dosages that the most resistant quadruple mutant DHFR allele is favored by selection.
143 s generate severely dwarfed plants, with the quadruple mutant displaying reproductive lethality.
144 he mouse Mesp2 mutant, in the zebrafish Mesp quadruple mutant embryos the positions of somite boundar
147 ed in a phytochrome interacting factor (pif) quadruple mutant in the dark and increased in a phytochr
148 when dormancy is induced, we used a nced2569 quadruple mutant in which ABA deficiency is mostly restr
152 In a dga1Deltalro1Deltaare1Deltaare2Delta quadruple mutant lacking all four triacylglycerol- and s
154 ng a human fH binding region on PorB2 of the quadruple mutant of strain 4243 with a chimeric protein
155 he five-residue H chimera with the CDV F-ODP quadruple mutant partially restores activity, indicating
156 hogenic phenotypes of cop1-6 pif1 and of the quadruple mutant pifq both in the dark and in far-red li
157 he PYR/PYLs, we analysed pyr1/pyl1/pyl2/pyl4 quadruple mutant plants and found strong insensitivities
160 type, and histochemical analysis of the rwa quadruple mutant stem indicates defects in cell differen
162 verall degree of wall acetylation in the rwa quadruple mutant was reduced by 63% compared with the wi
166 , yfnI, yqgS and yvgJ single, triple and the quadruple mutant, showed that LTA production was only ab
167 loss of ATS activity in the ats cna phb phv quadruple mutant, showing that CNA/PHB/PHV act in concer
168 defects could only be observed in the family quadruple mutant, which also showed the strongest change
176 ion of the gas was detected in a hydrogenase quadruple-mutant strain containing deletions in the hya,
177 ed in its virulence characteristics, and the quadruple-mutant strain had the same (greatly attenuated
178 collection of 30 simple, double, triple, and quadruple mutants affected in SAD-coding genes and there
179 ess, selected pme single, double, triple and quadruple mutants allowed significantly more growth of P
184 Genetic analysis of double, triple, and quadruple mutants confirmed that XLGs and Gbg functional
187 of gibberellin (GA) or by introducing della quadruple mutants in the nfl background, suggesting that
188 atty acid desaturase3-2 (fad3-2) fad7-2 fad8 quadruple mutants prevents increased lipid peroxidation
189 polymerase chain reaction data performed in quadruple mutants revealed altered phosphoinositide leve
191 d all four of the above-mentioned molecules (quadruple mutants), we recently identified a role for Po
197 f monomeric IgG for C1q by introduction of a quadruple mutation at the C1q binding site or via genera
199 the histidine-aspartate acid (HD) domain (a quadruple mutation) or in the GGDD motif of the Cmr-2alp
202 monly use 193 nm excimer or 266 nm frequency-quadrupled Nd:YAG lasers to ablate and ionize particles
203 of the species Camponotus pennsylvanicus by quadrupling nest space and by manually tracking 6.9 mill
204 Neurons from triple neurexin-1/2/3 or from quadruple neuroligin-1/2/3/4 conditional KO mice that la
205 re of a previously reported extremely strong quadruple NH...N AAAA-DDDD hydrogen-bond array [5.4] (K(
209 stigate this question by comparing a typical quadrupling-of-CO2 experiment with a simulation driven b
210 and NFH with and without alpha-internexin in quadruple- or quintuple-transfected SW13vim(-) cells.
211 erformance liquid chromatography-linear trap quadruple-Orbitrap-mass spectrometry (HPLC LTQ-Orbitrap
215 electric dipoles by light hole doping of the quadruple perovskite BiMn(7)O(12) In analogy with magnet
216 Here we show that an A- and B-site-ordered quadruple perovskite oxide, CaCu3Fe2Re2O12, has spin-pol
217 Optimization of CaCu3Fe2Re2O12 and related quadruple perovskite phases is expected to produce a new
220 AP share unique purine-binding geometry with quadruple pi-stacking interactions between adjacent aden
222 factor genes act downstream of SFPS, as the quadruple pif mutant pifq suppresses defects of sfps mut
226 ndles multiple junctions, triple points, and quadruple points in two dimensions, as well as triple li
227 SnRK1 repression is abrogated in double and quadruple pp2c knockout mutants, provoking, similarly to
229 However, compared with wild-type triple and quadruple pten knockouts, caulonemal cells grew faster,
230 aba1-6 mutant, or in ABA signaling, like the quadruple pyr/pyl mutant (pyr1pyl1pyl2pyl4), were more r
231 overlap between electrons in a semiconductor quadruple quantum dot array, we generate a series of coh
233 le mutant plants, but not other analyzed cpk quadruple/quintuple mutants, were defective in high CO(2
234 etrahydrocyclohepta[b]indoles, and a one-pot quadruple reaction sequence of the enynols generates dih
236 efficacy of 2 different optimized nonbismuth quadruple regimens in areas of high resistance to antimi
241 ition, exhibits dual-, triple-, and at least quadruple-shape memory effects, all highly tunable witho
243 ty in children and adolescents worldwide has quadrupled since 1975 and is a key predictor of obesity
244 of data available for querying has more than quadrupled since it went into production and OLS functio
246 ic core, an intraprotein hydrogen bond and a quadruple stacking interaction between U1A and U1hpII.
248 est pair will form a bound binary, while the quadruple stellar system itself is bound but unstable on
249 Guanine-rich oligonucleotides can fold into quadruple-stranded helical structures known as G-quadrup
251 tion (greater than 1,000 astronomical units) quadruple system composed of a young protostar and three
252 plified by polymerase chain reaction using a quadruple-tagging set of primers specific for E. coli ea
254 they had a second trimester screening test (Quadruple test) and treated as positive only if this wer
256 The maternal mortality ratio in Ragh was quadruple that in Kabul (713 per 100 000 livebirths, 95%
258 nce interval [CI]: 16% to 28%) was more than quadruple the 5% average worldwide background rate of PE
261 week warning sign for ED influx of triple or quadruple the number of influenza cases compared to the
263 s study in African Americans, XPEB more than quadrupled the discoveries from the conventional approac
264 ) and time-dependent exposure to carbapenems quadrupled the hazard (hazard ratio, 4.087; 95% CI, 1.87
266 S613 with the liaF allele from isolate R712 quadrupled the MIC of daptomycin, whereas replacement of
267 of 150 mum ATP into female rat sciatic nerve quadrupled the number of axons growing into a lesion epi
268 Although the Haber-Bosch process more than quadrupled the productivity of agricultural crops, chemi
271 otagmin, inclusion of both Munc13 and Munc18 quadruples the Ca(2+)-triggered amplitude and achieves C
273 cytic glutamate uptake using TFB-TBOA nearly quadruples the duration of SD in layers 2-3 of visual co
274 identifies nearly 300 novel EBV transcripts, quadrupling the size of the annotated viral transcriptom
275 hyroid hormone-dependent glycolytic rate and quadrupling the transcription of thyroid hormone target
276 an macrophages to TSE for 20 hours more than quadrupled their production of MMP14-positive MVs (contr
277 ithromycin and Levofloxacin-based sequential quadruple therapies as first-line treatment options and
279 arithromycin [PAMC]) and traditional bismuth quadruple therapy (PPI + bismuth + metronidazole + tetra
280 ne strategies include concomitant nonbismuth quadruple therapy (proton pump inhibitor [PPI] + amoxici
283 Second-line therapies should be bismuth quadruple therapy or levofloxacin triple therapy, depend
286 matography (LC) nano electrospray ionization quadruple time-of-flight (nano-ESI-Q-TOF) mass spectrome
288 sing ultra-performance liquid chromatography-quadruple time-of-flight high-sensitivity mass spectrome
289 uid chromatography coupled with electrospray quadruple time-of-flight mass spectrometry (IPRP-UPLC ES
290 ultra-high-performance liquid chromatography quadruple time-of-flight mass spectrometry method in 648
292 detector and an ultrahigh resolution hybrid quadruple-time-of-flight mass spectrometer with ESI sour
298 time illustrates the relevance of the larger quadruple VirB6 paralogs by demonstrating the protein ex
299 sults suggest that E. chaffeensis VirB9, the quadruple VirB6 proteins, and the VirB6-2 80-kDa fragmen
300 no connections were discovered [15], we used quadruple whole-cell recordings to screen connectivity w