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1  the developing rat optic nerve, raising the question of why 2As do not normally develop in the optic
2 made receptor kinases redundant, raising the question of why a more complex two-step mechanism (recep
3                              This raises the question of why a particular circuit architecture is sel
4 e sequence does not provide an answer to the question of why a protein binds only to a small subset o
5  rule is often not optimal, which raises the question of why a rule with such properties should have
6 e one important explanation for the puzzling question of why addicted individuals continue drug consu
7 o, Italy, June 2015, focused entirely on the question of why advanced cancer cure is so uncommon desp
8  rapid eye movement sleep (REM), raising the question of why and how specialized sleep evolved.
9 both within and between species, raising the questions of why and how some vocal behaviors evolve.
10 ortant practical implications but also raise questions of why and how this strategy would benefit tra
11 f coding sequences in some cases, raises the question of why bacteria need so many GGDEF enzymes.
12 fers a potential answer to the long-standing question of why bioremediation frequently stalls at cis-
13 ly dominate over sensitive ones, raising the question of why both antagonistic and nonantagonistic mi
14 sponse to different RNA viruses, raising the question of why cells need to limit PKR activity.
15                                          The question of why certain products of the reaction are sta
16 owever, we have no answer to the fundamental question of why certain proteins are allergens, while ot
17 dings provide insight into the long-standing questions of why CNVs at different genomic loci increase
18        This raises the important and general question of why CO2 is not formed directly.
19 was not rescued by healthy rods, raising the question of why cones are not protected by the rod-deriv
20                              This raises the question of why Darwin puts natural selection first and
21 eover, her account provides no answer to the question of why direct active teaching seems to be a uni
22  genetically sensitive design to address the question of why educational achievement is so highly her
23          The latter observation resolves the question of why eukaryotes are insensitive to the antibi
24 ip, our findings serve to inform the related question of why eye contact is deferentially avoided in
25  small marsupial has thrown new light on the question of why females typically mate with several male
26 ent through clonal anergy has long posed the question of why fill the circulating B cell repertoire w
27 n nucleosomes and resolves the long-standing question of why H3K4me3 levels are coupled with H3 acety
28       Before modeling OTCD, we addressed the question of why hiPSC-Heps generally secrete less urea t
29                       This result raises the question of why home health care services did not produc
30  work suggests an answer to the longstanding question of why humans make "irrational" economic choice
31 his emotion into account, we can address the question of why humans seek to learn, teach, and innovat
32                              This raised the question of why IL-4 alone failed to produce PKCd phosph
33                  The disparity brings up the question of why improvements in hypertension control app
34                    This raises the important questions of why, in such regimes, the Kolmogorov spectr
35 charomyces cerevisiae raises the fundamental question of why introns have been retained in approximat
36 ng Regnase-1 in memory, but leaving open the question of why it is downregulated during sleep-depende
37                         However, the central question of why it took these populations approximately
38 ction of either L- or D-enantiomers, and the question of why living systems on the Earth consist of L
39 provide a new perspective on the fundamental question of why long-term conflicts are so difficult to
40 ous other developmental processes raises the question of why mammals would have evolved a different w
41 e present-day rate, resolves a long-standing question of why many cratons were stabilized in the Neoa
42             Our work recasts the theoretical question of why memory transformation occurs, shifting t
43                               To address the question of why mice deficient in gammadelta T cells res
44 cations of these findings in relation to the question of why mitochondria, more so than plastids and
45 obalamin biosynthetic pathway and raises the question of why most PLP-dependent decarboxylases are co
46  geranylation pathway, as well as answer the question of why nature uses such a hydrophobic modificat
47 thus providing insight into the longstanding question of why nerves are required for axolotl limb reg
48       These findings lead to the interesting question of why NMD factors evolved; are they for RNA-qu
49             We also answer the long-standing question of why NSUN4, but not its enzymatic activity, i
50 ch-policymaker engagement, framed around the questions of why, on what, with whom, when, where and ho
51 while others are not is addressed, as is the question of why only select alpha-ethereal hydrogen atom
52                                          The question of why our conceptions of space and time are in
53 The 'flip' mechanism has thrown light on the question of why partial agonists are not efficacious at
54 icle, we address this puzzle and the related question of why pathogens often have diversity at multip
55 guide protein folding and raises the broader question of why proteins have charged residues on their
56 hich proteases activate this channel and the question of why proteolysis has evolved as a mechanism o
57                                To pursue the question of why Rpo41, which resembles the single polype
58  In essence, this Review addresses the broad question of why seizures occur when they occur.
59                              This raises the question of why severe ketosis is accompanied by acidosi
60 er non-filter-feeding cetaceans, raising the question of why smaller animals do not utilize this fora
61 ltiple 3'-->5' exoribonucleases, raising the question of why so many activities are present in the co
62 ical castes in social insects, including the question of why soldiers appear to be so much rarer in b
63 e and criticism and offered insight into the question of why some individuals fare better than others
64          Extant research is evaluated on the questions of why (some) people are (more) susceptible to
65  deceptively simple, yet inherently complex, question of why species richness is lower in secondary f
66  not produce amylose revives a long-standing question of why starch granules contain amylose, rather
67 A, and can activate transcription, raising a question of why Stat1 is required.
68                            This leads to the question of why subordinate males help in the absence of
69 ers are seriously hampered by the unanswered question of why such outbreaks occur.
70  appropriate DNA binding domain, raising the question of why Tat has been directed to the RNA.
71                               To address the question of why Tau is GDP-tubulin-biased, we tested whe
72 e, they do not address the equally important question of why the complex systems of life would have e
73 es are most likely correct, which raises the question of why the computational methods, while sometim
74 red to the wild-type.(2) This has led to the question of why the efficacy of the NA inhibitors is red
75                 These experiments raised the question of why the Gol region of the incipient head pro
76                         Here, we address the question of why the influenza A virus hemagglutinin (HA)
77 rance of diminishing returns but raising the question of why the input prices of academic R&D are ris
78 6 in the canonical conformation, raising the question of why the intermediate between these two struc
79                    These studies address the question of why the last two reactions in pyrimidine nuc
80  results shed new light on the long-standing question of why the major groups of parasitic lice are n
81 inance modifiers between them, and raise the question of why the non-recombining regions of some sex
82                             We addressed the question of why the promoter that regulates GL epsilon t
83 draining lymph nodes to directly address the question of why the smaller droplets were less effective
84  FP, and also investigated the long-standing question of why the sugar content of this sap is ~30-fol
85     We have begun to address the fundamental question of why the TdT promoter contains an Inr rather
86 ovide insight into the unsolved evolutionary question of why the three domains of life each carry the
87 of the EDM is also intimately related to the question of why the Universe has so little antimatter.
88                  These findings generate the question of why the virus targets two major autophagy ad
89  efficacy in a different phylum, raising the question of why these genes have not spread more widely.
90                     This paper addresses the question of why these rotational barriers, which at the
91  equivalent, naturally leading us to ask the question of why these self-supervised objectives are bet
92 tial for catalytic activity which raises the question of why they are conserved.
93 ous bacterial phenotype, but the fundamental question of why they are shaped this way remains unanswe
94                               We address the question of why they have such a complex structure and a
95                       By asking the ultimate question of "why" this process evolved in multicellular
96 hypothesis for the cochlea, leaving open the question of why two neurotrophins are required for prope
97 ration in the cerebellum in SCA17 raises the question of why ubiquitously expressed polyQ proteins ca
98 anistic explanation to the nearly 100-yr-old question of why vitamin A deficiency causes so many path
99                   These observations beg the question of why vitreal PDGFs fail to activate PDGFRalph
100 ished from ageing to take us from the common question of why we age to a more revealing question that